Barriers to healthcare predict reduced health-related quality of life in autistic adults without intellectual disability / Nicole DAVID ; Pascal Rahlff ; Hannah König ; Sophia Dückert ; Petia Gewohn ; Frank Erik ; Kai VOGELEY ; Daniel SCHOTTLE ; Alexander Konnopka ; Holger Schulz ; Judith Peth in Autism, 29-2 (February 2025)  

Public ISBD [article]  inAutism > 29-2 (February 2025) . - p.476-489 Titre : Barriers to healthcare predict reduced health-related quality of life in autistic adults without intellectual disability : Autism Type de document : Texte imprimé et/ou numérique Auteurs : Nicole DAVID, Auteur ; Pascal Rahlff, Auteur ; Hannah König, Auteur ; Sophia Dückert, Auteur ; Petia Gewohn, Auteur ; Frank Erik, Auteur ; Kai VOGELEY, Auteur ; Daniel SCHOTTLE, Auteur ; Alexander Konnopka, Auteur ; Holger Schulz, Auteur ; Judith Peth, Auteur Article en page(s) : p.476-489 Langues : Anglais (eng) Mots-clés : adults  autism spectrum disorders  health services  quality of life Index. décimale : PER Périodiques Résumé : Autistic adults frequently show increased physical or mental health conditions and impairments in social, occupational, and other life domains. Accordingly, they often report reduced health-related quality of life. Yet, numerous barriers prevent effective healthcare for autistic adults. To date, the impact of healthcare barriers on health-related quality of life in autism has not been investigated. We, thus, sought to investigate the health-related quality of life of autistic adults without intellectual disability in Germany and analyze previously reported and novel predictors of health-related quality of life including healthcare barriers using multiple linear regression. Within a nationwide online survey, 311 autistic adults completed the Short-Form Health Survey and the Barriers to Healthcare Checklist. Demographic, clinical, and healthcare-related predictors were also assessed. Participants showed below-average mental and significantly reduced physical health-related quality of life compared to a German normative sample. Several independent variables differentially predicted mental and physical health-related quality of life. Healthcare barriers resulted as the only predictor, which explained variations in both domains: the more barriers autistic adults experienced, the lower their mental and physical health-related quality of life. Barriers emerged as the strongest predictor for mental health-related quality of life. Our results raise awareness for the barriers autistic adults experience in getting appropriate healthcare and the possible consequences for the individual. Improved healthcare access might contribute to better health-related quality of life in autism. Lay abstract Health-related quality of life reflects a person?s perspective on their well-being in physical, mental, social, work-related, and other aspects of health or life. Autistic adults typically report difficulties in many or all of these domains and, thus, often experience their health-related quality of life being reduced. Nonetheless, they do not obtain the professional support they need and report barriers to accessing or receiving appropriate healthcare. We know little about the impact of barriers to healthcare on health-related quality of life in autistic adults. In the present study, 311 autistic adults without intellectual disability in Germany completed an online survey on their current health-related quality of life and the number of barriers to healthcare they experience. In addition, they were asked about their personal and clinical background as well as about the amount of healthcare and support they recently received. We investigated how this information and, particularly, barriers to healthcare explained variations in individual levels of health-related quality of life. We found that barriers to healthcare, compared to most other variables, were a strong predictor of health-related quality of life: The more barriers autistic adults reported, the lower their experienced psychological and physical well-being. To our knowledge, this is the first paper to examine the relationship between barriers to healthcare and health-related quality of life in autism. Our results suggest that healthcare providers need to become aware of the barriers individuals with autism have in seeking and getting healthcare. Improved access to services might contribute to better health-related quality of life in autistic adults. En ligne : https://dx.doi.org/10.1177/13623613241275406 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=547 [article] Barriers to healthcare predict reduced health-related quality of life in autistic adults without intellectual disability : Autism [Texte imprimé et/ou numérique] / Nicole DAVID, Auteur ; Pascal Rahlff, Auteur ; Hannah König, Auteur ; Sophia Dückert, Auteur ; Petia Gewohn, Auteur ; Frank Erik, Auteur ; Kai VOGELEY, Auteur ; Daniel SCHOTTLE, Auteur ; Alexander Konnopka, Auteur ; Holger Schulz, Auteur ; Judith Peth, Auteur . - p.476-489. Langues : Anglais (eng) in Autism > 29-2 (February 2025) . - p.476-489 Mots-clés : adults  autism spectrum disorders  health services  quality of life Index. décimale : PER Périodiques Résumé : Autistic adults frequently show increased physical or mental health conditions and impairments in social, occupational, and other life domains. Accordingly, they often report reduced health-related quality of life. Yet, numerous barriers prevent effective healthcare for autistic adults. To date, the impact of healthcare barriers on health-related quality of life in autism has not been investigated. We, thus, sought to investigate the health-related quality of life of autistic adults without intellectual disability in Germany and analyze previously reported and novel predictors of health-related quality of life including healthcare barriers using multiple linear regression. Within a nationwide online survey, 311 autistic adults completed the Short-Form Health Survey and the Barriers to Healthcare Checklist. Demographic, clinical, and healthcare-related predictors were also assessed. Participants showed below-average mental and significantly reduced physical health-related quality of life compared to a German normative sample. Several independent variables differentially predicted mental and physical health-related quality of life. Healthcare barriers resulted as the only predictor, which explained variations in both domains: the more barriers autistic adults experienced, the lower their mental and physical health-related quality of life. Barriers emerged as the strongest predictor for mental health-related quality of life. Our results raise awareness for the barriers autistic adults experience in getting appropriate healthcare and the possible consequences for the individual. Improved healthcare access might contribute to better health-related quality of life in autism. Lay abstract Health-related quality of life reflects a person?s perspective on their well-being in physical, mental, social, work-related, and other aspects of health or life. Autistic adults typically report difficulties in many or all of these domains and, thus, often experience their health-related quality of life being reduced. Nonetheless, they do not obtain the professional support they need and report barriers to accessing or receiving appropriate healthcare. We know little about the impact of barriers to healthcare on health-related quality of life in autistic adults. In the present study, 311 autistic adults without intellectual disability in Germany completed an online survey on their current health-related quality of life and the number of barriers to healthcare they experience. In addition, they were asked about their personal and clinical background as well as about the amount of healthcare and support they recently received. We investigated how this information and, particularly, barriers to healthcare explained variations in individual levels of health-related quality of life. We found that barriers to healthcare, compared to most other variables, were a strong predictor of health-related quality of life: The more barriers autistic adults reported, the lower their experienced psychological and physical well-being. To our knowledge, this is the first paper to examine the relationship between barriers to healthcare and health-related quality of life in autism. Our results suggest that healthcare providers need to become aware of the barriers individuals with autism have in seeking and getting healthcare. Improved access to services might contribute to better health-related quality of life in autistic adults. En ligne : https://dx.doi.org/10.1177/13623613241275406 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=547

Mirror me: Imitative responses in adults with autism / Odette SCHUNKE in Autism, 20-2 (February 2016)  

Public ISBD [article]  inAutism > 20-2 (February 2016) . - p.134-144 Titre : Mirror me: Imitative responses in adults with autism Type de document : Texte imprimé et/ou numérique Auteurs : Odette SCHUNKE, Auteur ; Daniel SCHOTTLE, Auteur ; Eik VETTORAZZI, Auteur ; Valerie BRANDT, Auteur ; Ursula KAHL, Auteur ; Tobias BÄUMER, Auteur ; Christos GANOS, Auteur ; Nicole DAVID, Auteur ; Ina PEIKER, Auteur ; Andreas K ENGEL, Auteur ; Marcel BRASS, Auteur ; Alexander MUNCHAU, Auteur Article en page(s) : p.134-144 Langues : Anglais (eng) Mots-clés : autism  imitation  interference  mirror neurons  reaction times Index. décimale : PER Périodiques Résumé : Dysfunctions of the human mirror neuron system have been postulated to underlie some deficits in autism spectrum disorders including poor imitative performance and impaired social skills. Using three reaction time experiments addressing mirror neuron system functions under simple and complex conditions, we examined 20 adult autism spectrum disorder participants and 20 healthy controls matched for age, gender and education. Participants performed simple finger-lifting movements in response to (1) biological finger and non-biological dot movement stimuli, (2) acoustic stimuli and (3) combined visual-acoustic stimuli with different contextual (compatible/incompatible) and temporal (simultaneous/asynchronous) relation. Mixed model analyses revealed slower reaction times in autism spectrum disorder. Both groups responded faster to biological compared to non-biological stimuli (Experiment 1) implying intact processing advantage for biological stimuli in autism spectrum disorder. In Experiment 3, both groups had similar ‘interference effects’ when stimuli were presented simultaneously. However, autism spectrum disorder participants had abnormally slow responses particularly when incompatible stimuli were presented consecutively. Our results suggest imitative control deficits rather than global imitative system impairments. En ligne : http://dx.doi.org/10.1177/1362361315571757 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278 [article] Mirror me: Imitative responses in adults with autism [Texte imprimé et/ou numérique] / Odette SCHUNKE, Auteur ; Daniel SCHOTTLE, Auteur ; Eik VETTORAZZI, Auteur ; Valerie BRANDT, Auteur ; Ursula KAHL, Auteur ; Tobias BÄUMER, Auteur ; Christos GANOS, Auteur ; Nicole DAVID, Auteur ; Ina PEIKER, Auteur ; Andreas K ENGEL, Auteur ; Marcel BRASS, Auteur ; Alexander MUNCHAU, Auteur . - p.134-144. Langues : Anglais (eng) in Autism > 20-2 (February 2016) . - p.134-144 Mots-clés : autism  imitation  interference  mirror neurons  reaction times Index. décimale : PER Périodiques Résumé : Dysfunctions of the human mirror neuron system have been postulated to underlie some deficits in autism spectrum disorders including poor imitative performance and impaired social skills. Using three reaction time experiments addressing mirror neuron system functions under simple and complex conditions, we examined 20 adult autism spectrum disorder participants and 20 healthy controls matched for age, gender and education. Participants performed simple finger-lifting movements in response to (1) biological finger and non-biological dot movement stimuli, (2) acoustic stimuli and (3) combined visual-acoustic stimuli with different contextual (compatible/incompatible) and temporal (simultaneous/asynchronous) relation. Mixed model analyses revealed slower reaction times in autism spectrum disorder. Both groups responded faster to biological compared to non-biological stimuli (Experiment 1) implying intact processing advantage for biological stimuli in autism spectrum disorder. In Experiment 3, both groups had similar ‘interference effects’ when stimuli were presented simultaneously. However, autism spectrum disorder participants had abnormally slow responses particularly when incompatible stimuli were presented consecutively. Our results suggest imitative control deficits rather than global imitative system impairments. En ligne : http://dx.doi.org/10.1177/1362361315571757 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278

Quantitative Sensory Testing in adults with Autism Spectrum Disorders / Odette FRÜNDT in Journal of Autism and Developmental Disorders, 47-4 (April 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-4 (April 2017) . - p.1183-1192 Titre : Quantitative Sensory Testing in adults with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Odette FRÜNDT, Auteur ; Wiebke GRASHORN, Auteur ; Daniel SCHOTTLE, Auteur ; Ina PEIKER, Auteur ; Nicole DAVID, Auteur ; Andreas K. ENGEL, Auteur ; Katarina FORKMANN, Auteur ; Nathalie WROBEL, Auteur ; Alexander MUNCHAU, Auteur ; Ulrike BINGEL, Auteur Article en page(s) : p.1183-1192 Langues : Anglais (eng) Mots-clés : Autism  Quantitative sensory testing  Sensory thresholds  Hyposensitivity  Hypersensitivity Index. décimale : PER Périodiques Résumé : Altered sensory perception has been found in patients with autism spectrum disorders (ASD) and might be related to aberrant sensory perception thresholds. We used the well-established, standardized Quantitative sensory testing (QST) protocol of the German Research Network on Neuropathic Pain to investigate 13 somatosensory parameters including thermal and tactile detection and pain thresholds in 13 ASD adults and 13 matched healthy controls with normal IQ values. There were no group differences between somatosensory detection and pain thresholds. Two ASD patients showed paradoxical heat sensations and another two ASD subjects presented dynamic mechanical allodynia; somatosensory features that were absent in controls. These findings suggest that central mechanisms during complex stimulus integration rather than peripheral dysfunctions probably determine somatosensory alterations in ASD. En ligne : http://dx.doi.org/10.1007/s10803-017-3041-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=304 [article] Quantitative Sensory Testing in adults with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Odette FRÜNDT, Auteur ; Wiebke GRASHORN, Auteur ; Daniel SCHOTTLE, Auteur ; Ina PEIKER, Auteur ; Nicole DAVID, Auteur ; Andreas K. ENGEL, Auteur ; Katarina FORKMANN, Auteur ; Nathalie WROBEL, Auteur ; Alexander MUNCHAU, Auteur ; Ulrike BINGEL, Auteur . - p.1183-1192. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-4 (April 2017) . - p.1183-1192 Mots-clés : Autism  Quantitative sensory testing  Sensory thresholds  Hyposensitivity  Hypersensitivity Index. décimale : PER Périodiques Résumé : Altered sensory perception has been found in patients with autism spectrum disorders (ASD) and might be related to aberrant sensory perception thresholds. We used the well-established, standardized Quantitative sensory testing (QST) protocol of the German Research Network on Neuropathic Pain to investigate 13 somatosensory parameters including thermal and tactile detection and pain thresholds in 13 ASD adults and 13 matched healthy controls with normal IQ values. There were no group differences between somatosensory detection and pain thresholds. Two ASD patients showed paradoxical heat sensations and another two ASD subjects presented dynamic mechanical allodynia; somatosensory features that were absent in controls. These findings suggest that central mechanisms during complex stimulus integration rather than peripheral dysfunctions probably determine somatosensory alterations in ASD. En ligne : http://dx.doi.org/10.1007/s10803-017-3041-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=304

Right Temporoparietal Gray Matter Predicts Accuracy of Social Perception in the Autism Spectrum / Nicole DAVID in Journal of Autism and Developmental Disorders, 44-6 (June 2014)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 44-6 (June 2014) . - p.1433-1446 Titre : Right Temporoparietal Gray Matter Predicts Accuracy of Social Perception in the Autism Spectrum Type de document : Texte imprimé et/ou numérique Auteurs : Nicole DAVID, Auteur ; Johannes SCHULTZ, Auteur ; Elizabeth MILNE, Auteur ; Odette SCHUNKE, Auteur ; Daniel SCHOTTLE, Auteur ; Alexander MUNCHAU, Auteur ; Markus SIEGEL, Auteur ; Kai VOGELEY, Auteur ; Andreas K. ENGEL, Auteur Article en page(s) : p.1433-1446 Langues : Anglais (eng) Mots-clés : Autism  Asperger syndrome  Motion coherence  Animacy  Social perception  Voxel-based morphometry Index. décimale : PER Périodiques Résumé : Individuals with an autism spectrum disorder (ASD) show hallmark deficits in social perception. These difficulties might also reflect fundamental deficits in integrating visual signals. We contrasted predictions of a social perception and a spatial–temporal integration deficit account. Participants with ASD and matched controls performed two tasks: the first required spatiotemporal integration of global motion signals without social meaning, the second required processing of socially relevant local motion. The ASD group only showed differences to controls in social motion evaluation. In addition, gray matter volume in the temporal–parietal junction correlated positively with accuracy in social motion perception in the ASD group. Our findings suggest that social–perceptual difficulties in ASD cannot be reduced to deficits in spatial–temporal integration. En ligne : http://dx.doi.org/10.1007/s10803-013-2008-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=233 [article] Right Temporoparietal Gray Matter Predicts Accuracy of Social Perception in the Autism Spectrum [Texte imprimé et/ou numérique] / Nicole DAVID, Auteur ; Johannes SCHULTZ, Auteur ; Elizabeth MILNE, Auteur ; Odette SCHUNKE, Auteur ; Daniel SCHOTTLE, Auteur ; Alexander MUNCHAU, Auteur ; Markus SIEGEL, Auteur ; Kai VOGELEY, Auteur ; Andreas K. ENGEL, Auteur . - p.1433-1446. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 44-6 (June 2014) . - p.1433-1446 Mots-clés : Autism  Asperger syndrome  Motion coherence  Animacy  Social perception  Voxel-based morphometry Index. décimale : PER Périodiques Résumé : Individuals with an autism spectrum disorder (ASD) show hallmark deficits in social perception. These difficulties might also reflect fundamental deficits in integrating visual signals. We contrasted predictions of a social perception and a spatial–temporal integration deficit account. Participants with ASD and matched controls performed two tasks: the first required spatiotemporal integration of global motion signals without social meaning, the second required processing of socially relevant local motion. The ASD group only showed differences to controls in social motion evaluation. In addition, gray matter volume in the temporal–parietal junction correlated positively with accuracy in social motion perception in the ASD group. Our findings suggest that social–perceptual difficulties in ASD cannot be reduced to deficits in spatial–temporal integration. En ligne : http://dx.doi.org/10.1007/s10803-013-2008-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=233

---

1 (1 - 4 / 4)