Using a developmental perspective to examine the moderating effects of marriage on heavy episodic drinking in a young adult sample enriched for risk / Seung Bin CHO in Development and Psychopathology, 33-3 (August 2021)  

Public ISBD [article]  inDevelopment and Psychopathology > 33-3 (August 2021) . - p.1097-1106 Titre : Using a developmental perspective to examine the moderating effects of marriage on heavy episodic drinking in a young adult sample enriched for risk Type de document : Texte imprimé et/ou numérique Auteurs : Seung Bin CHO, Auteur ; Rebecca L. SMITH, Auteur ; Kathleen K. BUCHOLZ, Auteur ; Grace F. C. CHAN, Auteur ; Howard J. EDENBERG, Auteur ; Victor HESSELBROCK, Auteur ; John KRAMER, Auteur ; Vivia V. MCCUTCHEON, Auteur ; John NURNBERGER, Auteur ; Marc SCHUCKIT, Auteur ; Yong ZANG, Auteur ; Danielle M. DICK, Auteur ; Jessica E. SALVATORE, Auteur Article en page(s) : p.1097-1106 Langues : Anglais (eng) Mots-clés : alcohol  development  genetics  marital status  young adults Index. décimale : PER Périodiques Résumé : Many studies demonstrate that marriage protects against risky alcohol use and moderates genetic influences on alcohol outcomes; however, previous work has not considered these effects from a developmental perspective or in high-risk individuals. These represent important gaps, as it cannot be assumed that marriage has uniform effects across development or in high-risk samples. We took a longitudinal developmental approach to examine whether marital status was associated with heavy episodic drinking (HED), and whether marital status moderated polygenic influences on HED. Our sample included 937 individuals (53.25% female) from the Collaborative Study on the Genetics of Alcoholism who reported their HED and marital status biennially between the ages of 21 and 25. Polygenic risk scores (PRS) were derived from a genome-wide association study of alcohol consumption. Marital status was not associated with HED; however, we observed pathogenic gene-by-environment effects that changed across young adulthood. Among those who married young (age 21), individuals with higher PRS reported more HED; however, these effects decayed over time. The same pattern was found in supplementary analyses using parental history of alcohol use disorder as the index of genetic liability. Our findings indicate that early marriage may exacerbate risk for those with higher polygenic load. En ligne : http://dx.doi.org/10.1017/S0954579420000371 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457 [article] Using a developmental perspective to examine the moderating effects of marriage on heavy episodic drinking in a young adult sample enriched for risk [Texte imprimé et/ou numérique] / Seung Bin CHO, Auteur ; Rebecca L. SMITH, Auteur ; Kathleen K. BUCHOLZ, Auteur ; Grace F. C. CHAN, Auteur ; Howard J. EDENBERG, Auteur ; Victor HESSELBROCK, Auteur ; John KRAMER, Auteur ; Vivia V. MCCUTCHEON, Auteur ; John NURNBERGER, Auteur ; Marc SCHUCKIT, Auteur ; Yong ZANG, Auteur ; Danielle M. DICK, Auteur ; Jessica E. SALVATORE, Auteur . - p.1097-1106. Langues : Anglais (eng) in Development and Psychopathology > 33-3 (August 2021) . - p.1097-1106 Mots-clés : alcohol  development  genetics  marital status  young adults Index. décimale : PER Périodiques Résumé : Many studies demonstrate that marriage protects against risky alcohol use and moderates genetic influences on alcohol outcomes; however, previous work has not considered these effects from a developmental perspective or in high-risk individuals. These represent important gaps, as it cannot be assumed that marriage has uniform effects across development or in high-risk samples. We took a longitudinal developmental approach to examine whether marital status was associated with heavy episodic drinking (HED), and whether marital status moderated polygenic influences on HED. Our sample included 937 individuals (53.25% female) from the Collaborative Study on the Genetics of Alcoholism who reported their HED and marital status biennially between the ages of 21 and 25. Polygenic risk scores (PRS) were derived from a genome-wide association study of alcohol consumption. Marital status was not associated with HED; however, we observed pathogenic gene-by-environment effects that changed across young adulthood. Among those who married young (age 21), individuals with higher PRS reported more HED; however, these effects decayed over time. The same pattern was found in supplementary analyses using parental history of alcohol use disorder as the index of genetic liability. Our findings indicate that early marriage may exacerbate risk for those with higher polygenic load. En ligne : http://dx.doi.org/10.1017/S0954579420000371 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457

Validation of the Developmental, Dimensional and Diagnostic Interview (3Di) Among Chinese Children in a Child Psychiatry Clinic in Hong Kong / Kelly Y. C. LAI in Journal of Autism and Developmental Disorders, 45-5 (May 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-5 (May 2015) . - p.1230-1237 Titre : Validation of the Developmental, Dimensional and Diagnostic Interview (3Di) Among Chinese Children in a Child Psychiatry Clinic in Hong Kong Type de document : Texte imprimé et/ou numérique Auteurs : Kelly Y. C. LAI, Auteur ; Patrick W. L. LEUNG, Auteur ; Flora Y. M. MO, Auteur ; Marshall M. C. LEE, Auteur ; Caroline K. S. SHEA, Auteur ; Grace F. C. CHAN, Auteur ; Kiti K. I. CHE, Auteur ; Ernest S. L. LUK, Auteur ; Arthur D. P. MAK, Auteur ; Richard WARRINGTON, Auteur ; David SKUSE, Auteur Article en page(s) : p.1230-1237 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  3Di  Chinese  Validation Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a disorder with high levels of co-morbidities. The Developmental, Dimensional and Diagnostic Interview (3Di) is a relatively new instrument designed to provide dimensional as well as categorical assessment of autistic behaviours among children with normal intelligence. Its sound psychometric properties and relatively short administration time make it a versatile instrument. The 3Di was translated into Chinese (Cantonese) and its applicability among 194 clinic children was examined. Results found excellent reliability and validity, and achieved a sensitivity of 95 % and specificity of 77 %. It was able to capture the diagnosis of ASD among children presenting with attention deficit hyperactivity disorder. However, although the disorder of ASD is considered universal, the use of a western instrument in a Chinese context should also take note of cultural influences that may impact on the manifestation of its symptoms. En ligne : http://dx.doi.org/10.1007/s10803-014-2284-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259 [article] Validation of the Developmental, Dimensional and Diagnostic Interview (3Di) Among Chinese Children in a Child Psychiatry Clinic in Hong Kong [Texte imprimé et/ou numérique] / Kelly Y. C. LAI, Auteur ; Patrick W. L. LEUNG, Auteur ; Flora Y. M. MO, Auteur ; Marshall M. C. LEE, Auteur ; Caroline K. S. SHEA, Auteur ; Grace F. C. CHAN, Auteur ; Kiti K. I. CHE, Auteur ; Ernest S. L. LUK, Auteur ; Arthur D. P. MAK, Auteur ; Richard WARRINGTON, Auteur ; David SKUSE, Auteur . - p.1230-1237. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-5 (May 2015) . - p.1230-1237 Mots-clés : Autism spectrum disorder  3Di  Chinese  Validation Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a disorder with high levels of co-morbidities. The Developmental, Dimensional and Diagnostic Interview (3Di) is a relatively new instrument designed to provide dimensional as well as categorical assessment of autistic behaviours among children with normal intelligence. Its sound psychometric properties and relatively short administration time make it a versatile instrument. The 3Di was translated into Chinese (Cantonese) and its applicability among 194 clinic children was examined. Results found excellent reliability and validity, and achieved a sensitivity of 95 % and specificity of 77 %. It was able to capture the diagnosis of ASD among children presenting with attention deficit hyperactivity disorder. However, although the disorder of ASD is considered universal, the use of a western instrument in a Chinese context should also take note of cultural influences that may impact on the manifestation of its symptoms. En ligne : http://dx.doi.org/10.1007/s10803-014-2284-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259

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