Typical and Atypical Neurodevelopment for Face Specialization: An fMRI Study / Jane E. JOSEPH in Journal of Autism and Developmental Disorders, 45-6 (June 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-6 (June 2015) . - p.1725-1741 Titre : Typical and Atypical Neurodevelopment for Face Specialization: An fMRI Study Type de document : Texte imprimé et/ou numérique Auteurs : Jane E. JOSEPH, Auteur ; Xun ZHU, Auteur ; Andrew GUNDRAN, Auteur ; Faraday DAVIES, Auteur ; Jonathan D. CLARK, Auteur ; Lisa RUBLE, Auteur ; Paul GLASER, Auteur ; Ramesh S. BHATT, Auteur Article en page(s) : p.1725-1741 Langues : Anglais (eng) Mots-clés : Face processing  Typical development  Autism spectrum disorder  Undiagnosed siblings  fMRI Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorder (ASD) and their relatives process faces differently from typically developed (TD) individuals. In an fMRI face-viewing task, TD and undiagnosed sibling (SIB) children (5–18 years) showed face specialization in the right amygdala and ventromedial prefrontal cortex, with left fusiform and right amygdala face specialization increasing with age in TD subjects. SIBs showed extensive antero-medial temporal lobe activation for faces that was not present in any other group, suggesting a potential compensatory mechanism. In ASD, face specialization was minimal but increased with age in the right fusiform and decreased with age in the left amygdala, suggesting atypical development of a frontal–amygdala–fusiform system which is strongly linked to detecting salience and processing facial information. En ligne : http://dx.doi.org/10.1007/s10803-014-2330-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259 [article] Typical and Atypical Neurodevelopment for Face Specialization: An fMRI Study [Texte imprimé et/ou numérique] / Jane E. JOSEPH, Auteur ; Xun ZHU, Auteur ; Andrew GUNDRAN, Auteur ; Faraday DAVIES, Auteur ; Jonathan D. CLARK, Auteur ; Lisa RUBLE, Auteur ; Paul GLASER, Auteur ; Ramesh S. BHATT, Auteur . - p.1725-1741. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-6 (June 2015) . - p.1725-1741 Mots-clés : Face processing  Typical development  Autism spectrum disorder  Undiagnosed siblings  fMRI Index. décimale : PER Périodiques Résumé : Individuals with autism spectrum disorder (ASD) and their relatives process faces differently from typically developed (TD) individuals. In an fMRI face-viewing task, TD and undiagnosed sibling (SIB) children (5–18 years) showed face specialization in the right amygdala and ventromedial prefrontal cortex, with left fusiform and right amygdala face specialization increasing with age in TD subjects. SIBs showed extensive antero-medial temporal lobe activation for faces that was not present in any other group, suggesting a potential compensatory mechanism. In ASD, face specialization was minimal but increased with age in the right fusiform and decreased with age in the left amygdala, suggesting atypical development of a frontal–amygdala–fusiform system which is strongly linked to detecting salience and processing facial information. En ligne : http://dx.doi.org/10.1007/s10803-014-2330-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259

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