Emerging depression in adolescence coincides with accelerated frontal cortical thinning / Marieke G. N. BOS in Journal of Child Psychology and Psychiatry, 59-9 (September 2018)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 59-9 (September 2018) . - p.994-1002 Titre : Emerging depression in adolescence coincides with accelerated frontal cortical thinning Type de document : Texte imprimé et/ou numérique Auteurs : Marieke G. N. BOS, Auteur ; Sabine PETERS, Auteur ; Ferdi C. KAMP, Auteur ; Eveline A. CRONE, Auteur ; Christian K. TAMNES, Auteur Article en page(s) : p.994-1002 Langues : Anglais (eng) Mots-clés : Adolescence  brain development  longitudinal  depression  MRI  cerebral cortex Index. décimale : PER Périodiques Résumé : Background Adolescence is a transition period characterized by heightened emotional reactivity, which for some sets the stage for emerging depressive symptoms. Prior studies suggest that adolescent depression is associated with deviant cortical and subcortical brain structure. Longitudinal studies are, however, currently scarce, but critical to detect which adolescents are at risk for developing depressive symptoms. Methods In this longitudinal study, a community sample of 205 participants underwent magnetic resonance imaging (MRI) in three biennial waves (522 scans) spanning 5 years across ages 8?25 years. Depressive symptomatology was assessed using self-report at the third time point. Mixed models were used to examine the relations between structural brain development, specifically regional change in cortical thickness, surface area and subcortical volumes (hippocampus and amygdala), and depressive symptoms. Results Accelerated frontal lobe cortical thinning was observed in adolescents who developed depressive symptoms at the third time point. This effect remained after controlling for parent-reported affective problems at the first time point. Moreover, the effect was driven by specific lateral orbitofrontal and precentral regions. In addition, differential developmental trajectories of parietal cortical thickness and surface area in several regions were found for participants reporting higher depressive symptomatology, but these results did not survive correction for multiple comparisons. Volumes or developmental volume changes in hippocampus or amygdala were not related to depressive symptoms. Conclusions This study showed that emerging depression is associated with cortical thinning in frontal regions within individuals. These findings move beyond detecting cross-sectional correlations and set the stage for early detection, which may inform future intervention. En ligne : https://doi.org/10.1111/jcpp.12895 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 [article] Emerging depression in adolescence coincides with accelerated frontal cortical thinning [Texte imprimé et/ou numérique] / Marieke G. N. BOS, Auteur ; Sabine PETERS, Auteur ; Ferdi C. KAMP, Auteur ; Eveline A. CRONE, Auteur ; Christian K. TAMNES, Auteur . - p.994-1002. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 59-9 (September 2018) . - p.994-1002 Mots-clés : Adolescence  brain development  longitudinal  depression  MRI  cerebral cortex Index. décimale : PER Périodiques Résumé : Background Adolescence is a transition period characterized by heightened emotional reactivity, which for some sets the stage for emerging depressive symptoms. Prior studies suggest that adolescent depression is associated with deviant cortical and subcortical brain structure. Longitudinal studies are, however, currently scarce, but critical to detect which adolescents are at risk for developing depressive symptoms. Methods In this longitudinal study, a community sample of 205 participants underwent magnetic resonance imaging (MRI) in three biennial waves (522 scans) spanning 5 years across ages 8?25 years. Depressive symptomatology was assessed using self-report at the third time point. Mixed models were used to examine the relations between structural brain development, specifically regional change in cortical thickness, surface area and subcortical volumes (hippocampus and amygdala), and depressive symptoms. Results Accelerated frontal lobe cortical thinning was observed in adolescents who developed depressive symptoms at the third time point. This effect remained after controlling for parent-reported affective problems at the first time point. Moreover, the effect was driven by specific lateral orbitofrontal and precentral regions. In addition, differential developmental trajectories of parietal cortical thickness and surface area in several regions were found for participants reporting higher depressive symptomatology, but these results did not survive correction for multiple comparisons. Volumes or developmental volume changes in hippocampus or amygdala were not related to depressive symptoms. Conclusions This study showed that emerging depression is associated with cortical thinning in frontal regions within individuals. These findings move beyond detecting cross-sectional correlations and set the stage for early detection, which may inform future intervention. En ligne : https://doi.org/10.1111/jcpp.12895 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368

Emotion Control Predicts Internalizing and Externalizing Behavior Problems in Boys With and Without an Autism Spectrum Disorder / Marieke G. N. BOS in Journal of Autism and Developmental Disorders, 48-8 (August 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-8 (August 2018) . - p.2727-2739 Titre : Emotion Control Predicts Internalizing and Externalizing Behavior Problems in Boys With and Without an Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Marieke G. N. BOS, Auteur ; S. DIAMANTOPOULOU, Auteur ; L. STOCKMANN, Auteur ; Sander BEGEER, Auteur ; C. RIEFFE, Auteur Article en page(s) : p.2727-2739 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorders (ASD)  Comorbid psychopathology  Emotion regulation  Emotional control  Longitudinal study Index. décimale : PER Périodiques Résumé : Children and adolescents with Autism Spectrum Disorder (ASD) often show comorbid emotional and behavior problems. The aim of this longitudinal study is to examine the relation between emotion control (i.e., negative emotionality, emotion awareness, and worry/rumination) and the development of internalizing and externalizing problems. Boys with and without ASD (N = 157; age 9-15) were followed over a period of 1.5 years (3 waves). We found that baseline levels of worry/rumination was a specific predictor of later externalizing problems for boys with ASD. Furthermore, the developmental trajectory of worry/rumination predicted the development of internalizing and externalizing problems in both groups. Our findings suggest that worry/rumination may constitute a transdiagnostic factor underlying both internalizing and externalizing problems in boys with and without ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-3519-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=367 [article] Emotion Control Predicts Internalizing and Externalizing Behavior Problems in Boys With and Without an Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Marieke G. N. BOS, Auteur ; S. DIAMANTOPOULOU, Auteur ; L. STOCKMANN, Auteur ; Sander BEGEER, Auteur ; C. RIEFFE, Auteur . - p.2727-2739. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-8 (August 2018) . - p.2727-2739 Mots-clés : Autism Spectrum Disorders (ASD)  Comorbid psychopathology  Emotion regulation  Emotional control  Longitudinal study Index. décimale : PER Périodiques Résumé : Children and adolescents with Autism Spectrum Disorder (ASD) often show comorbid emotional and behavior problems. The aim of this longitudinal study is to examine the relation between emotion control (i.e., negative emotionality, emotion awareness, and worry/rumination) and the development of internalizing and externalizing problems. Boys with and without ASD (N = 157; age 9-15) were followed over a period of 1.5 years (3 waves). We found that baseline levels of worry/rumination was a specific predictor of later externalizing problems for boys with ASD. Furthermore, the developmental trajectory of worry/rumination predicted the development of internalizing and externalizing problems in both groups. Our findings suggest that worry/rumination may constitute a transdiagnostic factor underlying both internalizing and externalizing problems in boys with and without ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-3519-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=367

Emotional functioning and the development of internalizing and externalizing problems in young boys with and without autism spectrum disorder / B. LI in Autism, 24-1 (January 2020)  

Public ISBD [article]  inAutism > 24-1 (January 2020) . - p.200-210 Titre : Emotional functioning and the development of internalizing and externalizing problems in young boys with and without autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : B. LI, Auteur ; Marieke G. N. BOS, Auteur ; L. STOCKMANN, Auteur ; C. RIEFFE, Auteur Article en page(s) : p.200-210 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  comorbid psychopathology  emotion control  emotion recognition  emotion vocabulary  longitudinal study  preschool Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder are at risk of developing internalizing and externalizing problems. However, information on early development of behavior problems and the contributing role of emotional functioning in preschool children with autism spectrum disorder is scarce. This study collected data of boys with and without autism spectrum disorder (N = 156; age: 2-6 years) over three consecutive years (three waves), about their internalizing and externalizing symptoms and emotional functioning (i.e. emotion control, recognition, and vocabulary), using parent-report questionnaires. No age effect was found on internalizing or externalizing problems for boys with and without autism spectrum disorder. Boys with autism spectrum disorder displayed more behavior problems than their typically developing peers and showed lower levels of emotional functioning. Better emotion control and improved emotion recognition were associated with a decrease in problem behaviors for boys with and without autism spectrum disorder, whereas improved emotion vocabulary was uniquely related to a decrease in externalizing problems in boys with autism spectrum disorder. Our findings suggest that boys with and without autism spectrum disorder showed similar developmental courses of internalizing and externalizing problems. However, lower levels of emotional functioning were already more pronounced in boys with autism spectrum disorder at a young age. This contributes to higher levels of behavior problems. En ligne : http://dx.doi.org/10.1177/1362361319874644 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=414 [article] Emotional functioning and the development of internalizing and externalizing problems in young boys with and without autism spectrum disorder [Texte imprimé et/ou numérique] / B. LI, Auteur ; Marieke G. N. BOS, Auteur ; L. STOCKMANN, Auteur ; C. RIEFFE, Auteur . - p.200-210. Langues : Anglais (eng) in Autism > 24-1 (January 2020) . - p.200-210 Mots-clés : autism spectrum disorder  comorbid psychopathology  emotion control  emotion recognition  emotion vocabulary  longitudinal study  preschool Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder are at risk of developing internalizing and externalizing problems. However, information on early development of behavior problems and the contributing role of emotional functioning in preschool children with autism spectrum disorder is scarce. This study collected data of boys with and without autism spectrum disorder (N = 156; age: 2-6 years) over three consecutive years (three waves), about their internalizing and externalizing symptoms and emotional functioning (i.e. emotion control, recognition, and vocabulary), using parent-report questionnaires. No age effect was found on internalizing or externalizing problems for boys with and without autism spectrum disorder. Boys with autism spectrum disorder displayed more behavior problems than their typically developing peers and showed lower levels of emotional functioning. Better emotion control and improved emotion recognition were associated with a decrease in problem behaviors for boys with and without autism spectrum disorder, whereas improved emotion vocabulary was uniquely related to a decrease in externalizing problems in boys with autism spectrum disorder. Our findings suggest that boys with and without autism spectrum disorder showed similar developmental courses of internalizing and externalizing problems. However, lower levels of emotional functioning were already more pronounced in boys with autism spectrum disorder at a young age. This contributes to higher levels of behavior problems. En ligne : http://dx.doi.org/10.1177/1362361319874644 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=414

Longitudinal structural brain development and externalizing behavior in adolescence / Marieke G. N. BOS in Journal of Child Psychology and Psychiatry, 59-10 (October 2018)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 59-10 (October 2018) . - p.1061-1072 Titre : Longitudinal structural brain development and externalizing behavior in adolescence Type de document : Texte imprimé et/ou numérique Auteurs : Marieke G. N. BOS, Auteur ; L. M. WIERENGA, Auteur ; N. E. BLANKENSTEIN, Auteur ; E. SCHREUDERS, Auteur ; C. K. TAMNES, Auteur ; E. A. CRONE, Auteur Article en page(s) : p.1061-1072 Langues : Anglais (eng) Mots-clés : Externalizing behavior adolescence aggression longitudinal design structural MRI Index. décimale : PER Périodiques Résumé : BACKGROUND: Cross-sectional studies report relations between externalizing behavior and structural abnormalities in cortical thickness of prefrontal regions and volume reductions in subcortical regions. To understand how these associations emerge and develop, longitudinal designs are pivotal. METHOD: In the current longitudinal study, a community sample of children, adolescents and young adults (N = 271) underwent magnetic resonance imaging (MRI) in three biennial waves (680 scans). At each wave, aspects of externalizing behavior were assessed with parent-reported aggression and rule-breaking scores (Child Behavior Checklist), and self-reported aggression scores (Buss-Perry Aggression Questionnaire). Regions of interest (ROIs) were selected based on prior research: dorsolateral prefrontal (dlPFC), orbitofrontal (OFC), anterior cingulate cortex (ACC), insula, and parahippocampal cortex, as well as subcortical regions. Linear mixed models were used to assess the longitudinal relation between externalizing behavior and structural brain development. Structural covariance analyses were employed to identify whether longitudinal relations between ROIs (maturational coupling) were associated with externalizing behavior. RESULTS: Linear mixed model analyses showed a negative relation between parent-reported aggression and right hippocampal volume. Moreover, this longitudinal relation was driven by change in hippocampal volume and not initial volume of hippocampus at time point 1. Exploratory analyses showed that stronger maturational coupling between prefrontal regions, the limbic system, and striatum was associated with both low and high externalizing behavior. CONCLUSIONS: Together, these findings reinforce the hypothesis that altered structural brain development coincides with development of more externalizing behavior. These findings may guide future research on normative and deviant development of externalizing behavior. En ligne : http://dx.doi.org/10.1111/jcpp.12972 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369 [article] Longitudinal structural brain development and externalizing behavior in adolescence [Texte imprimé et/ou numérique] / Marieke G. N. BOS, Auteur ; L. M. WIERENGA, Auteur ; N. E. BLANKENSTEIN, Auteur ; E. SCHREUDERS, Auteur ; C. K. TAMNES, Auteur ; E. A. CRONE, Auteur . - p.1061-1072. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 59-10 (October 2018) . - p.1061-1072 Mots-clés : Externalizing behavior adolescence aggression longitudinal design structural MRI Index. décimale : PER Périodiques Résumé : BACKGROUND: Cross-sectional studies report relations between externalizing behavior and structural abnormalities in cortical thickness of prefrontal regions and volume reductions in subcortical regions. To understand how these associations emerge and develop, longitudinal designs are pivotal. METHOD: In the current longitudinal study, a community sample of children, adolescents and young adults (N = 271) underwent magnetic resonance imaging (MRI) in three biennial waves (680 scans). At each wave, aspects of externalizing behavior were assessed with parent-reported aggression and rule-breaking scores (Child Behavior Checklist), and self-reported aggression scores (Buss-Perry Aggression Questionnaire). Regions of interest (ROIs) were selected based on prior research: dorsolateral prefrontal (dlPFC), orbitofrontal (OFC), anterior cingulate cortex (ACC), insula, and parahippocampal cortex, as well as subcortical regions. Linear mixed models were used to assess the longitudinal relation between externalizing behavior and structural brain development. Structural covariance analyses were employed to identify whether longitudinal relations between ROIs (maturational coupling) were associated with externalizing behavior. RESULTS: Linear mixed model analyses showed a negative relation between parent-reported aggression and right hippocampal volume. Moreover, this longitudinal relation was driven by change in hippocampal volume and not initial volume of hippocampus at time point 1. Exploratory analyses showed that stronger maturational coupling between prefrontal regions, the limbic system, and striatum was associated with both low and high externalizing behavior. CONCLUSIONS: Together, these findings reinforce the hypothesis that altered structural brain development coincides with development of more externalizing behavior. These findings may guide future research on normative and deviant development of externalizing behavior. En ligne : http://dx.doi.org/10.1111/jcpp.12972 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369

The Understanding of Intentions, Desires and Beliefs in Young Children with Autism Spectrum Disorder / Evelien BROEKHOF in Journal of Autism and Developmental Disorders, 45-7 (July 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-7 (July 2015) . - p.2035-2045 Titre : The Understanding of Intentions, Desires and Beliefs in Young Children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Evelien BROEKHOF, Auteur ; Lizet KETELAAR, Auteur ; Lex STOCKMANN, Auteur ; Annette VAN ZIJP, Auteur ; Marieke G. N. BOS, Auteur ; Carolien RIEFFE, Auteur Année de publication : 2015 Article en page(s) : p.2035-2045 Langues : Anglais (eng) Mots-clés : Motivation  Pre-school children  Social behavior  Social cognition Index. décimale : PER Périodiques Résumé : This study provides a comprehensive picture of three core elements (Intentions, Desires, Beliefs) of Theory of Mind (ToM) in young children with autism spectrum disorder (ASD, n = 63, Mage = 55 months) and typically developing children (TD, n = 69, Mage = 54 months). Outcomes showed that ASD and TD children understood intentional actions equally well. Yet, children with ASD lacked the social interest to share intentions. Additionally, children with ASD had more difficulties in understanding others’ desires and beliefs compared to their TD peers. It is discussed whether the ToM delay seen in children with ASD is a motivational or a conceptual problem. En ligne : http://dx.doi.org/10.1007/s10803-015-2363-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=261 [article] The Understanding of Intentions, Desires and Beliefs in Young Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Evelien BROEKHOF, Auteur ; Lizet KETELAAR, Auteur ; Lex STOCKMANN, Auteur ; Annette VAN ZIJP, Auteur ; Marieke G. N. BOS, Auteur ; Carolien RIEFFE, Auteur . - 2015 . - p.2035-2045. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-7 (July 2015) . - p.2035-2045 Mots-clés : Motivation  Pre-school children  Social behavior  Social cognition Index. décimale : PER Périodiques Résumé : This study provides a comprehensive picture of three core elements (Intentions, Desires, Beliefs) of Theory of Mind (ToM) in young children with autism spectrum disorder (ASD, n = 63, Mage = 55 months) and typically developing children (TD, n = 69, Mage = 54 months). Outcomes showed that ASD and TD children understood intentional actions equally well. Yet, children with ASD lacked the social interest to share intentions. Additionally, children with ASD had more difficulties in understanding others’ desires and beliefs compared to their TD peers. It is discussed whether the ToM delay seen in children with ASD is a motivational or a conceptual problem. En ligne : http://dx.doi.org/10.1007/s10803-015-2363-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=261

---

1 (1 - 5 / 5)