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31 recherche sur le mot-clé 'MRI'




Incidental brain MRI findings in an autism twin study / Julio C. MONTERREY in Autism Research, 10-1 (January 2017)
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[article]
Titre : Incidental brain MRI findings in an autism twin study Type de document : Texte imprimé et/ou numérique Auteurs : Julio C. MONTERREY, Auteur ; Jennifer PHILIPS, Auteur ; Sue CLEVELAND, Auteur ; Serena TANAKA, Auteur ; Patrick BARNES, Auteur ; Joachim F. HALLMAYER, Auteur ; Alan L. REISS, Auteur ; Laura C. LAZZERONI, Auteur ; Antonio Y. HARDAN, Auteur Article en page(s) : p.113-120 Langues : Anglais (eng) Mots-clés : autism incidental findings neuroimaging MRI twins Index. décimale : PER Périodiques Résumé : Brain magnetic resonance imaging (MRI) studies suggest the prevalence of asymptomatic “incidental” findings (IF) in autism spectrum disorder (ASD) is similar to that of neurotypically developing (NT) controls. However, given the causes of IF may include both genetic and environmental factors, a twin study would facilitate comparing brain IF between ASD and NT subjects. MRI scans were examined to assess the prevalence of brain IF in twin “case pairs” (at least one twin with diagnosis of ASD) and twin “control pairs” (NT). Fifty case pairs and thirty-two control pairs were analyzed. IF were found in 68% of subjects with ASD, 71% of unaffected ASD siblings, and in 58% of control subjects (P?=?0.4). IF requiring clinical follow-up occurred more frequently in subjects with ASD compared to NT controls (17% vs. 5%, respectively; P?=?0.02). The concordance rate of IF in twins was 83%. A mixed effects model found younger age, male sex, and “family environment” to be significantly associated with IF. There was no difference in the prevalence rate of IF between ASD subjects and NT controls. More IF required clinical follow-up in ASD subjects compared to NT controls. The prevalence rate of IF observed in this twin study was higher than rates previously reported in singleton studies. Our results suggest the shared environment of twins – perhaps in utero – increases the risk of brain IF. Brain MRI in the initial work-up of ASD may be indicated in twins, especially in males. En ligne : http://dx.doi.org/10.1002/aur.1720 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=303
in Autism Research > 10-1 (January 2017) . - p.113-120[article] Incidental brain MRI findings in an autism twin study [Texte imprimé et/ou numérique] / Julio C. MONTERREY, Auteur ; Jennifer PHILIPS, Auteur ; Sue CLEVELAND, Auteur ; Serena TANAKA, Auteur ; Patrick BARNES, Auteur ; Joachim F. HALLMAYER, Auteur ; Alan L. REISS, Auteur ; Laura C. LAZZERONI, Auteur ; Antonio Y. HARDAN, Auteur . - p.113-120.
Langues : Anglais (eng)
in Autism Research > 10-1 (January 2017) . - p.113-120
Mots-clés : autism incidental findings neuroimaging MRI twins Index. décimale : PER Périodiques Résumé : Brain magnetic resonance imaging (MRI) studies suggest the prevalence of asymptomatic “incidental” findings (IF) in autism spectrum disorder (ASD) is similar to that of neurotypically developing (NT) controls. However, given the causes of IF may include both genetic and environmental factors, a twin study would facilitate comparing brain IF between ASD and NT subjects. MRI scans were examined to assess the prevalence of brain IF in twin “case pairs” (at least one twin with diagnosis of ASD) and twin “control pairs” (NT). Fifty case pairs and thirty-two control pairs were analyzed. IF were found in 68% of subjects with ASD, 71% of unaffected ASD siblings, and in 58% of control subjects (P?=?0.4). IF requiring clinical follow-up occurred more frequently in subjects with ASD compared to NT controls (17% vs. 5%, respectively; P?=?0.02). The concordance rate of IF in twins was 83%. A mixed effects model found younger age, male sex, and “family environment” to be significantly associated with IF. There was no difference in the prevalence rate of IF between ASD subjects and NT controls. More IF required clinical follow-up in ASD subjects compared to NT controls. The prevalence rate of IF observed in this twin study was higher than rates previously reported in singleton studies. Our results suggest the shared environment of twins – perhaps in utero – increases the risk of brain IF. Brain MRI in the initial work-up of ASD may be indicated in twins, especially in males. En ligne : http://dx.doi.org/10.1002/aur.1720 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=303 Methods for acquiring MRI data in children with autism spectrum disorder and intellectual impairment without the use of sedation / Christine W. NORDAHL in Journal of Neurodevelopmental Disorders, 8-1 (December 2016)
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Titre : Methods for acquiring MRI data in children with autism spectrum disorder and intellectual impairment without the use of sedation Type de document : Texte imprimé et/ou numérique Auteurs : Christine W. NORDAHL, Auteur ; M. MELLO, Auteur ; A. M. SHEN, Auteur ; M. D. SHEN, Auteur ; Laurie A. VISMARA, Auteur ; D. LI, Auteur ; K. HARRINGTON, Auteur ; C. TANASE, Auteur ; Beth GOODLIN-JONES, Auteur ; S. ROGERS, Auteur ; Leonard ABBEDUTO, Auteur ; David G. AMARAL, Auteur Article en page(s) : p.20 Langues : Anglais (eng) Mots-clés : Applied behavior analysis Brain Compliance Intellectual disability Low-functioning autism Mri Neurodevelopment Index. décimale : PER Périodiques Résumé : BACKGROUND: Magnetic resonance imaging (MRI) has been widely used in studies evaluating the neuropathology of autism spectrum disorder (ASD). Studies are often limited, however, to higher functioning individuals with ASD. MRI studies of individuals with ASD and comorbid intellectual disability (ID) are lacking, due in part to the challenges of acquiring images without the use of sedation. METHODS: Utilizing principles of applied behavior analysis (ABA), we developed a protocol for acquiring structural MRI scans in school-aged children with ASD and intellectual impairment. Board certified behavior analysts worked closely with each child and their parent(s), utilizing behavior change techniques such as pairing, shaping, desensitization, and positive reinforcement, through a series of mock scanner visits to prepare the child for the MRI scan. An objective, quantitative assessment of motion artifact in T1- and diffusion-weighted scans was implemented to ensure that high-quality images were acquired. RESULTS: The sample consisted of 17 children with ASD who are participants in the UC Davis Autism Phenome Project, a longitudinal MRI study aimed at evaluating brain developmental trajectories from early to middle childhood. At the time of their initial scan (2-3.5 years), all 17 children had a diagnosis of ASD and development quotient (DQ) <70. At the time of the current scan (9-13 years), 13 participants continued to have IQs in the range of ID (mean IQ = 54.1, sd = 12.1), and four participants had IQs in the normal range (mean = 102.2, sd = 7.5). The success rate in acquiring T1-weighted images that met quality assurance for acceptable motion artifact was 100 %. The success rate for acquiring high-quality diffusion-weighted images was 94 %. CONCLUSIONS: By using principles of ABA in a research MRI setting, it is feasible to acquire high-quality images in school-aged children with ASD and intellectual impairment without the use of sedation. This is especially critical to ensure that ongoing longitudinal studies of brain development can extend from infancy and early childhood into middle childhood in children with ASD at all levels of functioning, including those with comorbid ID. En ligne : http://dx.doi.org/10.1186/s11689-016-9154-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=348
in Journal of Neurodevelopmental Disorders > 8-1 (December 2016) . - p.20[article] Methods for acquiring MRI data in children with autism spectrum disorder and intellectual impairment without the use of sedation [Texte imprimé et/ou numérique] / Christine W. NORDAHL, Auteur ; M. MELLO, Auteur ; A. M. SHEN, Auteur ; M. D. SHEN, Auteur ; Laurie A. VISMARA, Auteur ; D. LI, Auteur ; K. HARRINGTON, Auteur ; C. TANASE, Auteur ; Beth GOODLIN-JONES, Auteur ; S. ROGERS, Auteur ; Leonard ABBEDUTO, Auteur ; David G. AMARAL, Auteur . - p.20.
Langues : Anglais (eng)
in Journal of Neurodevelopmental Disorders > 8-1 (December 2016) . - p.20
Mots-clés : Applied behavior analysis Brain Compliance Intellectual disability Low-functioning autism Mri Neurodevelopment Index. décimale : PER Périodiques Résumé : BACKGROUND: Magnetic resonance imaging (MRI) has been widely used in studies evaluating the neuropathology of autism spectrum disorder (ASD). Studies are often limited, however, to higher functioning individuals with ASD. MRI studies of individuals with ASD and comorbid intellectual disability (ID) are lacking, due in part to the challenges of acquiring images without the use of sedation. METHODS: Utilizing principles of applied behavior analysis (ABA), we developed a protocol for acquiring structural MRI scans in school-aged children with ASD and intellectual impairment. Board certified behavior analysts worked closely with each child and their parent(s), utilizing behavior change techniques such as pairing, shaping, desensitization, and positive reinforcement, through a series of mock scanner visits to prepare the child for the MRI scan. An objective, quantitative assessment of motion artifact in T1- and diffusion-weighted scans was implemented to ensure that high-quality images were acquired. RESULTS: The sample consisted of 17 children with ASD who are participants in the UC Davis Autism Phenome Project, a longitudinal MRI study aimed at evaluating brain developmental trajectories from early to middle childhood. At the time of their initial scan (2-3.5 years), all 17 children had a diagnosis of ASD and development quotient (DQ) <70. At the time of the current scan (9-13 years), 13 participants continued to have IQs in the range of ID (mean IQ = 54.1, sd = 12.1), and four participants had IQs in the normal range (mean = 102.2, sd = 7.5). The success rate in acquiring T1-weighted images that met quality assurance for acceptable motion artifact was 100 %. The success rate for acquiring high-quality diffusion-weighted images was 94 %. CONCLUSIONS: By using principles of ABA in a research MRI setting, it is feasible to acquire high-quality images in school-aged children with ASD and intellectual impairment without the use of sedation. This is especially critical to ensure that ongoing longitudinal studies of brain development can extend from infancy and early childhood into middle childhood in children with ASD at all levels of functioning, including those with comorbid ID. En ligne : http://dx.doi.org/10.1186/s11689-016-9154-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=348 Proton Magnetic Resonance Spectroscopy and MRI Reveal No Evidence for Brain Mitochondrial Dysfunction in Children with Autism Spectrum Disorder / Neva M. CORRIGAN in Journal of Autism and Developmental Disorders, 42-1 (January 2012)
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Titre : Proton Magnetic Resonance Spectroscopy and MRI Reveal No Evidence for Brain Mitochondrial Dysfunction in Children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Neva M. CORRIGAN, Auteur ; Dennis W.W. SHAW, Auteur ; Todd RICHARDS, Auteur ; Annette ESTES, Auteur ; Seth D. FRIEDMAN, Auteur ; Helen PETROPOULOS, Auteur ; Alan ARTRU, Auteur ; Stephen R. DAGER, Auteur Année de publication : 2012 Article en page(s) : p.105-115 Langues : Anglais (eng) Mots-clés : Autism Developmental disorders MRS MRI Mitochondrial disorders Brain metabolism Lactate Index. décimale : PER Périodiques Résumé : Brain mitochondrial dysfunction has been proposed as an etiologic factor in autism spectrum disorder (ASD). Proton magnetic resonance spectroscopic imaging ( 1 HMRS) and MRI were used to assess for evidence of brain mitochondrial dysfunction in longitudinal samples of children with ASD or developmental delay (DD), and cross-sectionally in typically developing (TD) children at 3–4, 6–7 and 9–10 years-of-age. A total of 239 studies from 130 unique participants (54ASD, 22DD, 54TD) were acquired. 1 HMRS and MRI revealed no evidence for brain mitochondrial dysfunction in the children with ASD. Findings do not support a substantive role for brain mitochondrial abnormalities in the etiology or symptom expression of ASD, nor the widespread use of hyperbaric oxygen treatment that has been advocated on the basis of this proposed relationship. En ligne : http://dx.doi.org/10.1007/s10803-011-1216-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=151
in Journal of Autism and Developmental Disorders > 42-1 (January 2012) . - p.105-115[article] Proton Magnetic Resonance Spectroscopy and MRI Reveal No Evidence for Brain Mitochondrial Dysfunction in Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Neva M. CORRIGAN, Auteur ; Dennis W.W. SHAW, Auteur ; Todd RICHARDS, Auteur ; Annette ESTES, Auteur ; Seth D. FRIEDMAN, Auteur ; Helen PETROPOULOS, Auteur ; Alan ARTRU, Auteur ; Stephen R. DAGER, Auteur . - 2012 . - p.105-115.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-1 (January 2012) . - p.105-115
Mots-clés : Autism Developmental disorders MRS MRI Mitochondrial disorders Brain metabolism Lactate Index. décimale : PER Périodiques Résumé : Brain mitochondrial dysfunction has been proposed as an etiologic factor in autism spectrum disorder (ASD). Proton magnetic resonance spectroscopic imaging ( 1 HMRS) and MRI were used to assess for evidence of brain mitochondrial dysfunction in longitudinal samples of children with ASD or developmental delay (DD), and cross-sectionally in typically developing (TD) children at 3–4, 6–7 and 9–10 years-of-age. A total of 239 studies from 130 unique participants (54ASD, 22DD, 54TD) were acquired. 1 HMRS and MRI revealed no evidence for brain mitochondrial dysfunction in the children with ASD. Findings do not support a substantive role for brain mitochondrial abnormalities in the etiology or symptom expression of ASD, nor the widespread use of hyperbaric oxygen treatment that has been advocated on the basis of this proposed relationship. En ligne : http://dx.doi.org/10.1007/s10803-011-1216-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=151 A systematic review of brain MRI findings in monogenic disorders strongly associated with autism spectrum disorder / V. FREWER in Journal of Child Psychology and Psychiatry, 62-11 (November 2021)
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Titre : A systematic review of brain MRI findings in monogenic disorders strongly associated with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : V. FREWER, Auteur ; C. P. GILCHRIST, Auteur ; S. E. COLLINS, Auteur ; K. WILLIAMS, Auteur ; M. L. SEAL, Auteur ; R. J. LEVENTER, Auteur ; D. J. AMOR, Auteur Article en page(s) : p.1339-1352 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnostic imaging/genetics Autistic Disorder Brain/diagnostic imaging Humans Magnetic Resonance Imaging Neuroimaging Autism spectrum disorder Mri magnetic resonance imaging monogenic disorders Index. décimale : PER Périodiques Résumé : BACKGROUND: Research on monogenic forms of autism spectrum disorder (autism) can inform our understanding of genetic contributions to the autism phenotype; yet, there is much to be learned about the pathways from gene to brain structure to behavior. This systematic review summarizes and evaluates research on brain magnetic resonance imaging (MRI) findings in monogenic conditions that have strong association with autism. This will improve understanding of the impact of genetic variability on brain structure and related behavioral traits in autism. METHODS: The search strategy for this systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Risk of bias (ROB) assessment was completed on included studies using the Newcastle-Ottawa Scales. RESULTS: Of 4,287 studies screened, 69 were included pertaining to 13 of the top 20 genes with the strongest association with autism. The greatest number of studies related to individuals with PTEN variants and autism. Brain MRI abnormalities were reported for 12 of the 13 genes studied, and in 51.7% of participants across all 13 genes, including 100% of participants with ARID1B variants. Specific MRI findings were highly variable, with no clear patterns emerging within or between the 13 genes, although white matter abnormalities were the most common. Few studies reported specific details about methods for acquisition and processing of brain MRI, and descriptors for brain abnormalities were variable. ROB assessment indicated high ROB for all studies, largely due to small sample sizes and lack of comparison groups. CONCLUSIONS: Brain abnormalities are common in this population of individuals, in particular, children; however, a range of different brain abnormalities were reported within and between genes. Directions for future neuroimaging research in monogenic autism are suggested. En ligne : http://dx.doi.org/10.1111/jcpp.13510 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456
in Journal of Child Psychology and Psychiatry > 62-11 (November 2021) . - p.1339-1352[article] A systematic review of brain MRI findings in monogenic disorders strongly associated with autism spectrum disorder [Texte imprimé et/ou numérique] / V. FREWER, Auteur ; C. P. GILCHRIST, Auteur ; S. E. COLLINS, Auteur ; K. WILLIAMS, Auteur ; M. L. SEAL, Auteur ; R. J. LEVENTER, Auteur ; D. J. AMOR, Auteur . - p.1339-1352.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 62-11 (November 2021) . - p.1339-1352
Mots-clés : Autism Spectrum Disorder/diagnostic imaging/genetics Autistic Disorder Brain/diagnostic imaging Humans Magnetic Resonance Imaging Neuroimaging Autism spectrum disorder Mri magnetic resonance imaging monogenic disorders Index. décimale : PER Périodiques Résumé : BACKGROUND: Research on monogenic forms of autism spectrum disorder (autism) can inform our understanding of genetic contributions to the autism phenotype; yet, there is much to be learned about the pathways from gene to brain structure to behavior. This systematic review summarizes and evaluates research on brain magnetic resonance imaging (MRI) findings in monogenic conditions that have strong association with autism. This will improve understanding of the impact of genetic variability on brain structure and related behavioral traits in autism. METHODS: The search strategy for this systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Risk of bias (ROB) assessment was completed on included studies using the Newcastle-Ottawa Scales. RESULTS: Of 4,287 studies screened, 69 were included pertaining to 13 of the top 20 genes with the strongest association with autism. The greatest number of studies related to individuals with PTEN variants and autism. Brain MRI abnormalities were reported for 12 of the 13 genes studied, and in 51.7% of participants across all 13 genes, including 100% of participants with ARID1B variants. Specific MRI findings were highly variable, with no clear patterns emerging within or between the 13 genes, although white matter abnormalities were the most common. Few studies reported specific details about methods for acquisition and processing of brain MRI, and descriptors for brain abnormalities were variable. ROB assessment indicated high ROB for all studies, largely due to small sample sizes and lack of comparison groups. CONCLUSIONS: Brain abnormalities are common in this population of individuals, in particular, children; however, a range of different brain abnormalities were reported within and between genes. Directions for future neuroimaging research in monogenic autism are suggested. En ligne : http://dx.doi.org/10.1111/jcpp.13510 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 Arterial spin labeling provides a reliable neurobiological marker of autism spectrum disorder / B. E. YERYS in Journal of Neurodevelopmental Disorders, 10-1 (December 2018)
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Titre : Arterial spin labeling provides a reliable neurobiological marker of autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : B. E. YERYS, Auteur ; J. D. HERRINGTON, Auteur ; G. K. BARTLEY, Auteur ; H. S. LIU, Auteur ; J. A. DETRE, Auteur ; Robert T. SCHULTZ, Auteur Année de publication : 2018 Article en page(s) : 32 p. Langues : Anglais (eng) Mots-clés : Autism Blood flow Faces Mri Social cognition Social perception Index. décimale : PER Périodiques Résumé : BACKGROUND: Research on neurobiological markers of autism spectrum disorder (ASD) has been elusive. However, radionuclide studies of cerebral blood flow (CBF) have shown decreased blood flow (hypoperfusion) in the temporal lobes of individuals with ASD across ages and intelligence. This observation fits with current neuroscientific models that implicate temporal regions in social perception and social cognition. Arterial spin labeled perfusion MRI allows noninvasive quantification of regional CBF as part of a multimodal MRI protocol. This method is almost entirely absent from ASD research to date. Our a priori hypothesis was that children with ASD would present with hypoperfusion in the temporal lobes-most notably the fusiform gyrus (given its prominent role in ASD social perception deficits). We also sought to examine the reproducibility of CBF measures, and their relationship to individual differences in facial recognition and ASD symptoms. METHODS: A total of 58 males (33 with ASD) between the ages of 12 and 17 years participated in the study. All children completed two arterial spin labeling and structural (T1) scans using a 3 T Siemens Verio scanner approximately 8 weeks apart, as well as behavioral testing at time 1 that included diagnostic measures and the Benton Facial Recognition Test. CBF was the key dependent variable, as was facial recognition performance, and ASD symptoms. The two scans were used for reliability analyses. RESULTS: The ASD group showed hypoperfusion in the bilateral fusiform gyrus and in right inferior temporal gyrus. Intra-class correlations showed moderate to good reliability across time within both groups, and no diagnostic group x time interactions. CBF in the left fusiform gyrus was significantly positively correlated with facial recognition. No significant correlations were observed with core ASD symptoms. CONCLUSIONS: Arterial spin labeling revealed hypoperfusion in children with ASD in regions critical to social perception and cognition. The left fusiform gyrus plays an important role in facial recognition, and greater CBF in this region was correlated with more normative facial recognition performance in children with ASD. This study takes an important first step in establishing CBF of the temporal lobes as a reliable marker of ASD. En ligne : http://dx.doi.org/10.1186/s11689-018-9250-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386
in Journal of Neurodevelopmental Disorders > 10-1 (December 2018) . - 32 p.[article] Arterial spin labeling provides a reliable neurobiological marker of autism spectrum disorder [Texte imprimé et/ou numérique] / B. E. YERYS, Auteur ; J. D. HERRINGTON, Auteur ; G. K. BARTLEY, Auteur ; H. S. LIU, Auteur ; J. A. DETRE, Auteur ; Robert T. SCHULTZ, Auteur . - 2018 . - 32 p.
Langues : Anglais (eng)
in Journal of Neurodevelopmental Disorders > 10-1 (December 2018) . - 32 p.
Mots-clés : Autism Blood flow Faces Mri Social cognition Social perception Index. décimale : PER Périodiques Résumé : BACKGROUND: Research on neurobiological markers of autism spectrum disorder (ASD) has been elusive. However, radionuclide studies of cerebral blood flow (CBF) have shown decreased blood flow (hypoperfusion) in the temporal lobes of individuals with ASD across ages and intelligence. This observation fits with current neuroscientific models that implicate temporal regions in social perception and social cognition. Arterial spin labeled perfusion MRI allows noninvasive quantification of regional CBF as part of a multimodal MRI protocol. This method is almost entirely absent from ASD research to date. Our a priori hypothesis was that children with ASD would present with hypoperfusion in the temporal lobes-most notably the fusiform gyrus (given its prominent role in ASD social perception deficits). We also sought to examine the reproducibility of CBF measures, and their relationship to individual differences in facial recognition and ASD symptoms. METHODS: A total of 58 males (33 with ASD) between the ages of 12 and 17 years participated in the study. All children completed two arterial spin labeling and structural (T1) scans using a 3 T Siemens Verio scanner approximately 8 weeks apart, as well as behavioral testing at time 1 that included diagnostic measures and the Benton Facial Recognition Test. CBF was the key dependent variable, as was facial recognition performance, and ASD symptoms. The two scans were used for reliability analyses. RESULTS: The ASD group showed hypoperfusion in the bilateral fusiform gyrus and in right inferior temporal gyrus. Intra-class correlations showed moderate to good reliability across time within both groups, and no diagnostic group x time interactions. CBF in the left fusiform gyrus was significantly positively correlated with facial recognition. No significant correlations were observed with core ASD symptoms. CONCLUSIONS: Arterial spin labeling revealed hypoperfusion in children with ASD in regions critical to social perception and cognition. The left fusiform gyrus plays an important role in facial recognition, and greater CBF in this region was correlated with more normative facial recognition performance in children with ASD. This study takes an important first step in establishing CBF of the temporal lobes as a reliable marker of ASD. En ligne : http://dx.doi.org/10.1186/s11689-018-9250-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386 Differences in age-related effects on brain volume in Down syndrome as compared to Williams syndrome and typical development / M. E. KORAN in Journal of Neurodevelopmental Disorders, 6-1 (December 2014)
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PermalinkEmerging depression in adolescence coincides with accelerated frontal cortical thinning / Marieke G. N. BOS in Journal of Child Psychology and Psychiatry, 59-9 (September 2018)
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PermalinkEvidence against the "normalization" prediction of the early brain overgrowth hypothesis of autism / Lisa D. YANKOWITZ in Molecular Autism, 11 (2020)
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PermalinkFear Potentiated Startle in Children With Autism Spectrum Disorder: Association With Anxiety Symptoms and Amygdala Volume / David HESSL in Autism Research, 14-3 (March 2021)
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PermalinkFurther Commentary on Mitochondrial Dysfunction in Autism Spectrum Disorder: Assessment and Treatment Considerations / Stephen R. DAGER in Journal of Autism and Developmental Disorders, 42-4 (April 2012)
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