[article]
Titre : |
Higher autism in children of women with psychiatric diagnoses |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
Bridget M. WIECKOWSKI, Auteur ; Yelda MUKHTAR, Auteur ; John J. LEE, Auteur ; Guibo XING, Auteur ; Cheryl K. WALKER, Auteur |
Article en page(s) : |
p.10-20 |
Langues : |
Anglais (eng) |
Mots-clés : |
ASD Epidemiology Women Depression Pregnancy |
Index. décimale : |
PER Périodiques |
Résumé : |
To determine the extent to which medical record history of maternal psychiatric diagnoses was associated with offspring autism risk in a large, socio-demographically diverse birth cohort. This retrospective cohort study linked hospital discharge records for 8,951,763 California singleton births occurring 1/1/91-12/31/08 from the Office of Statewide Health Planning and Development with diagnostic and service records from the Department of Developmental Services. Medical records documenting maternal mood and anxiety disorders and schizophrenia ICD-9-CM codes were identified, and 42,423 children were categorized with a DSM-IV diagnosis of ‘autistic disorder’. Log-linear Poisson models explored the relationships between maternal psychiatric disorders and autism, adjusting for maternal education, race, country of birth, and parental age. Results Rates of maternal psychiatric diagnoses were lower than expected for the population, reflecting under-recognition and under-reporting by inpatient clinicians. In adjusted analyses, mothers diagnosed with one individual psychiatric condition were 1.2–2.8 times more likely to have a child who developed autism. Mothers diagnosed with any one or more psychiatric condition were twice as likely to have a child with autism compared with unaffected or unreported women (RR = 1.97; 95% CI 1.83–2.12). Women with a documented inpatient medical record history of psychiatric diagnosis were nearly twice as likely as women without such diagnoses to have a child later diagnosed with autism. These findings highlight the need for routine prenatal screening for psychiatric conditions, as well as enhanced neurobehavioral assessment of children born to these mothers to detect early autism signs and optimize intervention timeliness. |
En ligne : |
http://dx.doi.org/10.1016/j.rasd.2016.10.004 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298 |
in Research in Autism Spectrum Disorders > 33 (January 2017) . - p.10-20
[article] Higher autism in children of women with psychiatric diagnoses [Texte imprimé et/ou numérique] / Bridget M. WIECKOWSKI, Auteur ; Yelda MUKHTAR, Auteur ; John J. LEE, Auteur ; Guibo XING, Auteur ; Cheryl K. WALKER, Auteur . - p.10-20. Langues : Anglais ( eng) in Research in Autism Spectrum Disorders > 33 (January 2017) . - p.10-20
Mots-clés : |
ASD Epidemiology Women Depression Pregnancy |
Index. décimale : |
PER Périodiques |
Résumé : |
To determine the extent to which medical record history of maternal psychiatric diagnoses was associated with offspring autism risk in a large, socio-demographically diverse birth cohort. This retrospective cohort study linked hospital discharge records for 8,951,763 California singleton births occurring 1/1/91-12/31/08 from the Office of Statewide Health Planning and Development with diagnostic and service records from the Department of Developmental Services. Medical records documenting maternal mood and anxiety disorders and schizophrenia ICD-9-CM codes were identified, and 42,423 children were categorized with a DSM-IV diagnosis of ‘autistic disorder’. Log-linear Poisson models explored the relationships between maternal psychiatric disorders and autism, adjusting for maternal education, race, country of birth, and parental age. Results Rates of maternal psychiatric diagnoses were lower than expected for the population, reflecting under-recognition and under-reporting by inpatient clinicians. In adjusted analyses, mothers diagnosed with one individual psychiatric condition were 1.2–2.8 times more likely to have a child who developed autism. Mothers diagnosed with any one or more psychiatric condition were twice as likely to have a child with autism compared with unaffected or unreported women (RR = 1.97; 95% CI 1.83–2.12). Women with a documented inpatient medical record history of psychiatric diagnosis were nearly twice as likely as women without such diagnoses to have a child later diagnosed with autism. These findings highlight the need for routine prenatal screening for psychiatric conditions, as well as enhanced neurobehavioral assessment of children born to these mothers to detect early autism signs and optimize intervention timeliness. |
En ligne : |
http://dx.doi.org/10.1016/j.rasd.2016.10.004 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298 |
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