Atypical pupillary light reflex in 2–6-year-old children with autism spectrum disorders / Dinalankara M. R. DINALANKARA in Autism Research, 10-5 (May 2017)  

Public ISBD [article]  inAutism Research > 10-5 (May 2017) . - p.829-838 Titre : Atypical pupillary light reflex in 2–6-year-old children with autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Dinalankara M. R. DINALANKARA, Auteur ; Judith H. MILES, Auteur ; T. NICOLE TAKAHASHI, Auteur ; Gang YAO, Auteur Article en page(s) : p.829-838 Langues : Anglais (eng) Mots-clés : pupillary light reflex  autism  age  latency  pupil size  autonomic dysfunction Index. décimale : PER Périodiques Résumé : The purpose of this study was to investigate pupillary light reflex (PLR) in 2–6-years-old children with autism spectrum disorders (ASD). A total of 117 medication-free 2–6-year-old boys participated in this study. Sixty participants were diagnosed with ASD (the “ASD group”) and the other 57 were in the control group of typical development (the “TD group”). A questionnaire was completed by the parent/guardian for assessing potential dysfunctions in the autonomic nervous system (ANS). The base pupil radius, PLR latency, and constriction time showed a significant age-related trend in both the ASD and TD groups. The base pupil size increased with age in the typically developing children, but not in the ASD group. The ASD group showed more symptoms related to ANS dysfunctions. An association between abnormal sweating with base pupil radius and PLR constriction was observed in the TD group but not the ASD group. The different association of PLR parameters with ANS dysfunction may suggest disrupted autonomic controls in children with ASD. En ligne : http://dx.doi.org/10.1002/aur.1745 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=307 [article] Atypical pupillary light reflex in 2–6-year-old children with autism spectrum disorders [Texte imprimé et/ou numérique] / Dinalankara M. R. DINALANKARA, Auteur ; Judith H. MILES, Auteur ; T. NICOLE TAKAHASHI, Auteur ; Gang YAO, Auteur . - p.829-838. Langues : Anglais (eng) in Autism Research > 10-5 (May 2017) . - p.829-838 Mots-clés : pupillary light reflex  autism  age  latency  pupil size  autonomic dysfunction Index. décimale : PER Périodiques Résumé : The purpose of this study was to investigate pupillary light reflex (PLR) in 2–6-years-old children with autism spectrum disorders (ASD). A total of 117 medication-free 2–6-year-old boys participated in this study. Sixty participants were diagnosed with ASD (the “ASD group”) and the other 57 were in the control group of typical development (the “TD group”). A questionnaire was completed by the parent/guardian for assessing potential dysfunctions in the autonomic nervous system (ANS). The base pupil radius, PLR latency, and constriction time showed a significant age-related trend in both the ASD and TD groups. The base pupil size increased with age in the typically developing children, but not in the ASD group. The ASD group showed more symptoms related to ANS dysfunctions. An association between abnormal sweating with base pupil radius and PLR constriction was observed in the TD group but not the ASD group. The different association of PLR parameters with ANS dysfunction may suggest disrupted autonomic controls in children with ASD. En ligne : http://dx.doi.org/10.1002/aur.1745 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=307

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