Substance use through adolescence into early adulthood after childhood-diagnosed ADHD: findings from the MTA longitudinal study / Brooke S.G. MOLINA in Journal of Child Psychology and Psychiatry, 59-6 (June 2018)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 59-6 (June 2018) . - p.692-702 Titre : Substance use through adolescence into early adulthood after childhood-diagnosed ADHD: findings from the MTA longitudinal study Type de document : texte imprimé Auteurs : Brooke S.G. MOLINA, Auteur ; Andrea L. HOWARD, Auteur ; James M. SWANSON, Auteur ; Annamarie STEHLI, Auteur ; John T. MITCHELL, Auteur ; Traci M. KENNEDY, Auteur ; Jeffery N. EPSTEIN, Auteur ; L. Eugene ARNOLD, Auteur ; Lily HECHTMAN, Auteur ; Benedetto VITIELLO, Auteur ; Betsy HOZA, Auteur Article en page(s) : p.692-702 Langues : Anglais (eng) Mots-clés : Adhd  Attention deficit disorder  adolescence  drug abuse Index. décimale : PER Périodiques Résumé : BACKGROUND: Inconsistent findings exist regarding long-term substance use (SU) risk for children diagnosed with attention-deficit/hyperactivity disorder (ADHD). The observational follow-up of the Multimodal Treatment Study of Children with ADHD (MTA) provides an opportunity to assess long-term outcomes in a large, diverse sample. METHODS: Five hundred forty-seven children, mean age 8.5, diagnosed with DSM-IV combined-type ADHD and 258 classmates without ADHD (local normative comparison group; LNCG) completed the Substance Use Questionnaire up to eight times from mean age 10 to mean age 25. RESULTS: In adulthood, weekly marijuana use (32.8% ADHD vs. 21.3% LNCG) and daily cigarette smoking (35.9% vs. 17.5%) were more prevalent in the ADHD group than the LNCG. The cumulative record also revealed more early substance users in adolescence for ADHD (57.9%) than LNCG (41.9%), including younger first use of alcohol, cigarettes, marijuana, and illicit drugs. Alcohol and nonmarijuana illicit drug use escalated slightly faster in the ADHD group in early adolescence. Early SU predicted quicker SU escalation and more SU in adulthood for both groups. CONCLUSIONS: Frequent SU for young adults with childhood ADHD is accompanied by greater initial exposure at a young age and slightly faster progression. Early SU prevention and screening is critical before escalation to intractable levels. En ligne : http://dx.doi.org/10.1111/jcpp.12855 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=363 [article] Substance use through adolescence into early adulthood after childhood-diagnosed ADHD: findings from the MTA longitudinal study [texte imprimé] / Brooke S.G. MOLINA, Auteur ; Andrea L. HOWARD, Auteur ; James M. SWANSON, Auteur ; Annamarie STEHLI, Auteur ; John T. MITCHELL, Auteur ; Traci M. KENNEDY, Auteur ; Jeffery N. EPSTEIN, Auteur ; L. Eugene ARNOLD, Auteur ; Lily HECHTMAN, Auteur ; Benedetto VITIELLO, Auteur ; Betsy HOZA, Auteur . - p.692-702. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 59-6 (June 2018) . - p.692-702 Mots-clés : Adhd  Attention deficit disorder  adolescence  drug abuse Index. décimale : PER Périodiques Résumé : BACKGROUND: Inconsistent findings exist regarding long-term substance use (SU) risk for children diagnosed with attention-deficit/hyperactivity disorder (ADHD). The observational follow-up of the Multimodal Treatment Study of Children with ADHD (MTA) provides an opportunity to assess long-term outcomes in a large, diverse sample. METHODS: Five hundred forty-seven children, mean age 8.5, diagnosed with DSM-IV combined-type ADHD and 258 classmates without ADHD (local normative comparison group; LNCG) completed the Substance Use Questionnaire up to eight times from mean age 10 to mean age 25. RESULTS: In adulthood, weekly marijuana use (32.8% ADHD vs. 21.3% LNCG) and daily cigarette smoking (35.9% vs. 17.5%) were more prevalent in the ADHD group than the LNCG. The cumulative record also revealed more early substance users in adolescence for ADHD (57.9%) than LNCG (41.9%), including younger first use of alcohol, cigarettes, marijuana, and illicit drugs. Alcohol and nonmarijuana illicit drug use escalated slightly faster in the ADHD group in early adolescence. Early SU predicted quicker SU escalation and more SU in adulthood for both groups. CONCLUSIONS: Frequent SU for young adults with childhood ADHD is accompanied by greater initial exposure at a young age and slightly faster progression. Early SU prevention and screening is critical before escalation to intractable levels. En ligne : http://dx.doi.org/10.1111/jcpp.12855 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=363

Temperament multi-trajectory groups across adolescence: Associations with adulthood psychopathology and polygenic scores in TRAILS / Frances L. WANG in Development and Psychopathology, 38-2 (May 2026)  

Public ISBD [article]  inDevelopment and Psychopathology > 38-2 (May 2026) . - p.704-718 Titre : Temperament multi-trajectory groups across adolescence: Associations with adulthood psychopathology and polygenic scores in TRAILS Type de document : texte imprimé Auteurs : Frances L. WANG, Auteur ; Shirley DUONG, Auteur ; Heather M. JOSEPH, Auteur ; Traci M. KENNEDY, Auteur ; Catharina HARTMAN, Auteur Article en page(s) : p.704-718 Langues : Anglais (eng) Mots-clés : Externalizing  internalizing  polygenic risk score  temperament multi-trajectory groups Index. décimale : PER Périodiques Résumé : It is well-established that adolescents’ temperament trajectories predict future psychopathology. Less well understood is how temperament traits co-develop from adolescence to young adulthood. We characterized how youths’ trajectories of effortful control, frustration, affiliation, and shyness formed multi-trajectory groups and examined their associations with adulthood psychopathology and polygenic risk scores (PRS). Participants were drawn from a larger longitudinal cohort (N = 1412). Effortful control, frustration, affiliation, and shyness were measured four times from ages 10-23. Adulthood internalizing and externalizing problems were measured at ages 24–27. PRS for externalizing problems and major depressive disorder were calculated. Group-based multi-trajectory analyses showed that a five-group model fit best, including “high-risk” on all temperament traits, “undercontrolled” and exuberant, “low-risk” on all traits, “overcontrolled” and inhibited, and “low affiliation” groups that differed on both the levels and slopes of temperament traits over time. The undercontrolled group showed the highest, and overcontrolled the lowest, externalizing PRS scores. The high-risk group showed heightened scores on the depression PRS. We found specific linkages between the high-risk group and withdrawn/depressed symptoms and the high-risk and undercontrolled groups with externalizing problems. Findings shed light on developmental patterns of temperament in adolescence-to-adulthood and unique combinations of temperament trajectories with specific linkages to etiologic factors and psychopathology. En ligne : https://dx.doi.org/10.1017/S0954579425100680 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=586 [article] Temperament multi-trajectory groups across adolescence: Associations with adulthood psychopathology and polygenic scores in TRAILS [texte imprimé] / Frances L. WANG, Auteur ; Shirley DUONG, Auteur ; Heather M. JOSEPH, Auteur ; Traci M. KENNEDY, Auteur ; Catharina HARTMAN, Auteur . - p.704-718. Langues : Anglais (eng) in Development and Psychopathology > 38-2 (May 2026) . - p.704-718 Mots-clés : Externalizing  internalizing  polygenic risk score  temperament multi-trajectory groups Index. décimale : PER Périodiques Résumé : It is well-established that adolescents’ temperament trajectories predict future psychopathology. Less well understood is how temperament traits co-develop from adolescence to young adulthood. We characterized how youths’ trajectories of effortful control, frustration, affiliation, and shyness formed multi-trajectory groups and examined their associations with adulthood psychopathology and polygenic risk scores (PRS). Participants were drawn from a larger longitudinal cohort (N = 1412). Effortful control, frustration, affiliation, and shyness were measured four times from ages 10-23. Adulthood internalizing and externalizing problems were measured at ages 24–27. PRS for externalizing problems and major depressive disorder were calculated. Group-based multi-trajectory analyses showed that a five-group model fit best, including “high-risk” on all temperament traits, “undercontrolled” and exuberant, “low-risk” on all traits, “overcontrolled” and inhibited, and “low affiliation” groups that differed on both the levels and slopes of temperament traits over time. The undercontrolled group showed the highest, and overcontrolled the lowest, externalizing PRS scores. The high-risk group showed heightened scores on the depression PRS. We found specific linkages between the high-risk group and withdrawn/depressed symptoms and the high-risk and undercontrolled groups with externalizing problems. Findings shed light on developmental patterns of temperament in adolescence-to-adulthood and unique combinations of temperament trajectories with specific linkages to etiologic factors and psychopathology. En ligne : https://dx.doi.org/10.1017/S0954579425100680 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=586

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