Maternal smoking during pregnancy and offspring executive function: What do we know and what are the next steps? / Lauren MICALIZZI in Development and Psychopathology, 30-4 (October 2018)  

Public ISBD [article]  inDevelopment and Psychopathology > 30-4 (October 2018) . - p.1333-1354 Titre : Maternal smoking during pregnancy and offspring executive function: What do we know and what are the next steps? Type de document : Texte imprimé et/ou numérique Auteurs : Lauren MICALIZZI, Auteur ; Valerie S. KNOPIK, Auteur Article en page(s) : p.1333-1354 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Children exposed to maternal smoking during pregnancy (MSDP) exhibit difficulties in executive function (EF) from infancy through adolescence. Due to the developmental significance of EF as a predictor of adaptive functioning throughout the life span, the MSDP–EF relation has clear public health implications. In this paper, we provide a comprehensive review of the literature on the relationship between MSDP and offspring EF across development; consider brain-based assessments, animal models, and genetically informed studies in an effort to elucidate plausible pathways of effects; discuss implications for prevention and intervention; and make calls to action for future research. En ligne : http://dx.doi.org/10.1017/S0954579417001687 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 [article] Maternal smoking during pregnancy and offspring executive function: What do we know and what are the next steps? [Texte imprimé et/ou numérique] / Lauren MICALIZZI, Auteur ; Valerie S. KNOPIK, Auteur . - p.1333-1354. Langues : Anglais (eng) in Development and Psychopathology > 30-4 (October 2018) . - p.1333-1354 Index. décimale : PER Périodiques Résumé : Children exposed to maternal smoking during pregnancy (MSDP) exhibit difficulties in executive function (EF) from infancy through adolescence. Due to the developmental significance of EF as a predictor of adaptive functioning throughout the life span, the MSDP–EF relation has clear public health implications. In this paper, we provide a comprehensive review of the literature on the relationship between MSDP and offspring EF across development; consider brain-based assessments, animal models, and genetically informed studies in an effort to elucidate plausible pathways of effects; discuss implications for prevention and intervention; and make calls to action for future research. En ligne : http://dx.doi.org/10.1017/S0954579417001687 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368

Single nucleotide polymorphism heritability and differential patterns of genetic overlap between inattention and four neurocognitive factors in youth / Lauren MICALIZZI in Development and Psychopathology, 33-1 (February 2021)  

Public ISBD [article]  inDevelopment and Psychopathology > 33-1 (February 2021) . - p.76-86 Titre : Single nucleotide polymorphism heritability and differential patterns of genetic overlap between inattention and four neurocognitive factors in youth Type de document : Texte imprimé et/ou numérique Auteurs : Lauren MICALIZZI, Auteur ; Leslie A. BRICK, Auteur ; Marisa E. MARRACCINI, Auteur ; Chelsie E. BENCA-BACHMAN, Auteur ; Rohan H. C. PALMER, Auteur ; Valerie S. KNOPIK, Auteur Article en page(s) : p.76-86 Langues : Anglais (eng) Mots-clés : Gcta  adolescence  genetics  heritability  inattention  neurocognitive functioning Index. décimale : PER Périodiques Résumé : Theoretical models of attention-deficit/hyperactivity disorder implicate neurocognitive dysfunction, yet neurocognitive functioning covers a range of abilities that may not all be linked with inattention. This study (a) investigated the single nucleotide polymorphism (SNP) heritability (h2SNP) of inattention and aspects of neurocognitive efficiency (memory, social cognition, executive function, and complex cognition) based on additive genome-wide effects; (b) examined if there were shared genetic effects among inattention and each aspect of neurocognitive efficiency; and (c) conducted an exploratory genome-wide association study to identify genetic regions associated with inattention. The sample included 3,563 participants of the Philadelphia Neurodevelopmental Cohort, a general population sample aged 8-21 years who completed the Penn Neurocognitive Battery. Data on inattention was obtained with the Kiddie Schedule of Affective Disorders (adapted). Genomic relatedness matrix restricted maximum likelihood was implemented in genome-wide complex trait analysis. Analyses revealed significant h2SNP for inattention (20%, SE = 0.08), social cognition (13%, SE = 0.08), memory (17%, SE = 0.08), executive function (25%, SE = 0.08), and complex cognition (24%, SE = 0.08). There was a positive genetic correlation (0.67, SE = 0.37) and a negative residual covariance (-0.23, SE = 0.06) between inattention and social cognition. No SNPs reached genome-wide significance for inattention. Results suggest specificity in genetic overlap among inattention and different aspects of neurocognitive efficiency. En ligne : http://dx.doi.org/10.1017/s0954579419001573 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=442 [article] Single nucleotide polymorphism heritability and differential patterns of genetic overlap between inattention and four neurocognitive factors in youth [Texte imprimé et/ou numérique] / Lauren MICALIZZI, Auteur ; Leslie A. BRICK, Auteur ; Marisa E. MARRACCINI, Auteur ; Chelsie E. BENCA-BACHMAN, Auteur ; Rohan H. C. PALMER, Auteur ; Valerie S. KNOPIK, Auteur . - p.76-86. Langues : Anglais (eng) in Development and Psychopathology > 33-1 (February 2021) . - p.76-86 Mots-clés : Gcta  adolescence  genetics  heritability  inattention  neurocognitive functioning Index. décimale : PER Périodiques Résumé : Theoretical models of attention-deficit/hyperactivity disorder implicate neurocognitive dysfunction, yet neurocognitive functioning covers a range of abilities that may not all be linked with inattention. This study (a) investigated the single nucleotide polymorphism (SNP) heritability (h2SNP) of inattention and aspects of neurocognitive efficiency (memory, social cognition, executive function, and complex cognition) based on additive genome-wide effects; (b) examined if there were shared genetic effects among inattention and each aspect of neurocognitive efficiency; and (c) conducted an exploratory genome-wide association study to identify genetic regions associated with inattention. The sample included 3,563 participants of the Philadelphia Neurodevelopmental Cohort, a general population sample aged 8-21 years who completed the Penn Neurocognitive Battery. Data on inattention was obtained with the Kiddie Schedule of Affective Disorders (adapted). Genomic relatedness matrix restricted maximum likelihood was implemented in genome-wide complex trait analysis. Analyses revealed significant h2SNP for inattention (20%, SE = 0.08), social cognition (13%, SE = 0.08), memory (17%, SE = 0.08), executive function (25%, SE = 0.08), and complex cognition (24%, SE = 0.08). There was a positive genetic correlation (0.67, SE = 0.37) and a negative residual covariance (-0.23, SE = 0.06) between inattention and social cognition. No SNPs reached genome-wide significance for inattention. Results suggest specificity in genetic overlap among inattention and different aspects of neurocognitive efficiency. En ligne : http://dx.doi.org/10.1017/s0954579419001573 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=442

The roles of familial transmission and smoking during pregnancy on executive function skills: A sibling-comparison study / Valerie S. KNOPIK in Development and Psychopathology, 34-5 (December 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-5 (December 2022) . - p.1803-1815 Titre : The roles of familial transmission and smoking during pregnancy on executive function skills: A sibling-comparison study Type de document : Texte imprimé et/ou numérique Auteurs : Valerie S. KNOPIK, Auteur ; Lauren MICALIZZI, Auteur ; Kristine MARCEAU, Auteur ; Amy M. LOVISKA, Auteur ; Li YU, Auteur ; Alexandra BIEN, Auteur ; Emily ROLAN, Auteur ; Allison S. EVANS, Auteur ; Rohan H. C. PALMER, Auteur ; Andrew C. HEATH, Auteur Article en page(s) : p.1803-1815 Langues : Anglais (eng) Mots-clés : executive function  family studies  smoking during pregnancy Index. décimale : PER Périodiques Résumé : This research examines maternal smoking during pregnancy and risk for poorer executive function in siblings discordant for exposure. Data (N = 173 families) were drawn from the Missouri Mothers and Their Children study, a sample, identified using birth records (years 1998 “2005), in which mothers changed smoking behavior between two pregnancies (Child 1 [older sibling]: Mage = 12.99; Child 2 [younger sibling]: Mage = 10.19). A sibling comparison approach was used, providing a robust test for the association between maternal smoking during pregnancy and different aspects of executive function in early-mid adolescence. Results suggested within-family (i.e., potentially causal) associations between maternal smoking during pregnancy and one working memory task (visual working memory) and one response inhibition task (color-word interference), with increased exposure associated with decreased performance. Maternal smoking during pregnancy was not associated with stop-signal reaction time, cognitive flexibility/set-shifting, or auditory working memory. Initial within-family associations between maternal smoking during pregnancy and visual working memory as well as color-word interference were fully attenuated in a model including child and familial covariates. These findings indicate that exposure to maternal smoking during pregnancy may be associated with poorer performance on some, but not all skills assessed; however, familial transmission of risk for low executive function appears more important. En ligne : http://dx.doi.org/10.1017/S095457942200075X Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492 [article] The roles of familial transmission and smoking during pregnancy on executive function skills: A sibling-comparison study [Texte imprimé et/ou numérique] / Valerie S. KNOPIK, Auteur ; Lauren MICALIZZI, Auteur ; Kristine MARCEAU, Auteur ; Amy M. LOVISKA, Auteur ; Li YU, Auteur ; Alexandra BIEN, Auteur ; Emily ROLAN, Auteur ; Allison S. EVANS, Auteur ; Rohan H. C. PALMER, Auteur ; Andrew C. HEATH, Auteur . - p.1803-1815. Langues : Anglais (eng) in Development and Psychopathology > 34-5 (December 2022) . - p.1803-1815 Mots-clés : executive function  family studies  smoking during pregnancy Index. décimale : PER Périodiques Résumé : This research examines maternal smoking during pregnancy and risk for poorer executive function in siblings discordant for exposure. Data (N = 173 families) were drawn from the Missouri Mothers and Their Children study, a sample, identified using birth records (years 1998 “2005), in which mothers changed smoking behavior between two pregnancies (Child 1 [older sibling]: Mage = 12.99; Child 2 [younger sibling]: Mage = 10.19). A sibling comparison approach was used, providing a robust test for the association between maternal smoking during pregnancy and different aspects of executive function in early-mid adolescence. Results suggested within-family (i.e., potentially causal) associations between maternal smoking during pregnancy and one working memory task (visual working memory) and one response inhibition task (color-word interference), with increased exposure associated with decreased performance. Maternal smoking during pregnancy was not associated with stop-signal reaction time, cognitive flexibility/set-shifting, or auditory working memory. Initial within-family associations between maternal smoking during pregnancy and visual working memory as well as color-word interference were fully attenuated in a model including child and familial covariates. These findings indicate that exposure to maternal smoking during pregnancy may be associated with poorer performance on some, but not all skills assessed; however, familial transmission of risk for low executive function appears more important. En ligne : http://dx.doi.org/10.1017/S095457942200075X Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492

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