Misdiagnosis of High Function Autism Spectrum Disorders in Adults: An Italian Case Series / Candida Claudia LUCIANO in Autism - Open Access, 4-2 ([01/03/2014])  

Public ISBD [article]  inAutism - Open Access > 4-2 [01/03/2014] . - 8 p. Titre : Misdiagnosis of High Function Autism Spectrum Disorders in Adults: An Italian Case Series Type de document : Texte imprimé et/ou numérique Auteurs : Candida Claudia LUCIANO, Auteur ; Roberto KELLER, Auteur ; Pierluigi POLITI, Auteur ; Eugenio AGUGLIA, Auteur ; Francesca MAGNANO, Auteur ; Lorenzo BURTI, Auteur ; Francesca MURARO, Auteur ; Angela ARESI, Auteur ; Stefano DAMIANI, Auteur ; Domenico BERARDI, Auteur Article en page(s) : 8 p. Langues : Anglais (eng) Mots-clés : Autism  Pervasive development disorder  High function  Adulthood  Misdiagnosis Index. décimale : PER Périodiques Résumé : High Function (HF) Autism Spectrum Disorders (ASD) in adulthood is highly prevalent but insufficiently recognized. In Italy, in particular, awareness of this condition is still insufficient and many psychiatrists have no cases of HF ASD to mention. Adult patients with HF ASD come to the attention of Mental Health Services complaining of difficulties within their social context and interpersonal relationships. Objectives: Describe emblematic clinical examples of misdiagnosed HF ASD to understand reasons that conducted to misdiagnosis. Procedure: We contact five specialized Italian Center in diagnosis of ASD. Each center have to describe two or three emblematic cases of adult patient with diagnosis of ASD validated by ADOS-4 but referred to clinicians with another diagnosis, discussing about possible reasons of misdiagnosis. Sample and Results: We have collected 12 case reports (2 from Bologna center, 3 from Torino center, 3 from Pavia center, 2 from Verona center and 2 from Catania center) of adult HF ASD previously misdiagnosed. These cases shows important similarity across centers and highlight that if are taken into account only problems or symptoms that conduct patients to ask help, cases can easily suggest other psychiatric or personality disorders. Diagnosis becomes clear only after considering all the clinical features and a detailed developmental history. Conclusion: Psychiatrists who have insufficient experience of ASD may overlook some symptoms of the overall clinical picture and misdiagnose ASD as personality disorders, schizophrenia, phobia or even as a non-psychiatric condition, so is hopeful for future increased knowledge about HF ASD in adulthood. En ligne : https://dx.doi.org/10.4172/2165-7890.1000131 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=409 [article] Misdiagnosis of High Function Autism Spectrum Disorders in Adults: An Italian Case Series [Texte imprimé et/ou numérique] / Candida Claudia LUCIANO, Auteur ; Roberto KELLER, Auteur ; Pierluigi POLITI, Auteur ; Eugenio AGUGLIA, Auteur ; Francesca MAGNANO, Auteur ; Lorenzo BURTI, Auteur ; Francesca MURARO, Auteur ; Angela ARESI, Auteur ; Stefano DAMIANI, Auteur ; Domenico BERARDI, Auteur . - 8 p. Langues : Anglais (eng) in Autism - Open Access > 4-2 [01/03/2014] . - 8 p. Mots-clés : Autism  Pervasive development disorder  High function  Adulthood  Misdiagnosis Index. décimale : PER Périodiques Résumé : High Function (HF) Autism Spectrum Disorders (ASD) in adulthood is highly prevalent but insufficiently recognized. In Italy, in particular, awareness of this condition is still insufficient and many psychiatrists have no cases of HF ASD to mention. Adult patients with HF ASD come to the attention of Mental Health Services complaining of difficulties within their social context and interpersonal relationships. Objectives: Describe emblematic clinical examples of misdiagnosed HF ASD to understand reasons that conducted to misdiagnosis. Procedure: We contact five specialized Italian Center in diagnosis of ASD. Each center have to describe two or three emblematic cases of adult patient with diagnosis of ASD validated by ADOS-4 but referred to clinicians with another diagnosis, discussing about possible reasons of misdiagnosis. Sample and Results: We have collected 12 case reports (2 from Bologna center, 3 from Torino center, 3 from Pavia center, 2 from Verona center and 2 from Catania center) of adult HF ASD previously misdiagnosed. These cases shows important similarity across centers and highlight that if are taken into account only problems or symptoms that conduct patients to ask help, cases can easily suggest other psychiatric or personality disorders. Diagnosis becomes clear only after considering all the clinical features and a detailed developmental history. Conclusion: Psychiatrists who have insufficient experience of ASD may overlook some symptoms of the overall clinical picture and misdiagnose ASD as personality disorders, schizophrenia, phobia or even as a non-psychiatric condition, so is hopeful for future increased knowledge about HF ASD in adulthood. En ligne : https://dx.doi.org/10.4172/2165-7890.1000131 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=409

Psychometric properties of the Autism Spectrum Disorder in Adults Screening Questionnaire (ASDASQ) in a sample of Italian psychiatric outpatients / Laura FUSAR-POLI in Research in Autism Spectrum Disorders, 78 (October 2020)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 78 (October 2020) . - 101668 Titre : Psychometric properties of the Autism Spectrum Disorder in Adults Screening Questionnaire (ASDASQ) in a sample of Italian psychiatric outpatients Type de document : Texte imprimé et/ou numérique Auteurs : Laura FUSAR-POLI, Auteur ; Emanuele BISSO, Auteur ; Ilaria CONCAS, Auteur ; Teresa SURACE, Auteur ; Silvia TINACCI, Auteur ; Antonio VANELLA, Auteur ; Rosaria FURNARI, Auteur ; Maria Salvina SIGNORELLI, Auteur ; Lena NYLANDER, Auteur ; Eugenio AGUGLIA, Auteur Article en page(s) : 101668 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Psychiatry  Adult  Screening  Differential diagnosis  Misdiagnosis  Clinician-rated tool Index. décimale : PER Périodiques Résumé : Background The present study aimed to examine the reliability and validity of the Italian version of the Autism Spectrum Disorder in Adults Screening Questionnaire (ASDASQ), a screening tool for autism spectrum disorder (ASD) among psychiatric outpatients. Methods We recruited 340 subjects via an outpatient psychiatric service in Italy. Forty-eight had a diagnosis of ASD, confirmed after a comprehensive clinical assessment and the administration of the Autism Diagnostic Observation Schedule-2 (ADOS-2). The remaining 292 participants had other diagnoses, confirmed after a careful psychiatric evaluation and the administration of the Structured Clinical Interview for DSM-5 (SCID-5). The ASDASQ was administered to contact clinicians of each subject. Results The ASDASQ showed outstanding accuracy (AUC = 0.96) in discriminating between ASD and non-ASD patients, with good sensitivity (0.85) and specificity (0.92). Agreement with clinical diagnosis was substantial (k = 0.68). Internal consistency of the tool was good (Cronbach’s alpha = 0.82), while intra- (ICC = 0.97) and inter-rater reliability (ICC = 0.92) were excellent. We found also a moderate correlation between ASDASQ and ADOS-2 scores in the ASD sample (r = 0.56). Conclusion Our findings suggest that the ASDASQ, in the Italian adaptation, may be considered a quick, simple, and effective tool to screen for ASD among psychiatric outpatients. Further studies are needed to evaluate its utility in other clinical settings. En ligne : https://doi.org/10.1016/j.rasd.2020.101668 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Psychometric properties of the Autism Spectrum Disorder in Adults Screening Questionnaire (ASDASQ) in a sample of Italian psychiatric outpatients [Texte imprimé et/ou numérique] / Laura FUSAR-POLI, Auteur ; Emanuele BISSO, Auteur ; Ilaria CONCAS, Auteur ; Teresa SURACE, Auteur ; Silvia TINACCI, Auteur ; Antonio VANELLA, Auteur ; Rosaria FURNARI, Auteur ; Maria Salvina SIGNORELLI, Auteur ; Lena NYLANDER, Auteur ; Eugenio AGUGLIA, Auteur . - 101668. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 78 (October 2020) . - 101668 Mots-clés : Autism spectrum disorder  Psychiatry  Adult  Screening  Differential diagnosis  Misdiagnosis  Clinician-rated tool Index. décimale : PER Périodiques Résumé : Background The present study aimed to examine the reliability and validity of the Italian version of the Autism Spectrum Disorder in Adults Screening Questionnaire (ASDASQ), a screening tool for autism spectrum disorder (ASD) among psychiatric outpatients. Methods We recruited 340 subjects via an outpatient psychiatric service in Italy. Forty-eight had a diagnosis of ASD, confirmed after a comprehensive clinical assessment and the administration of the Autism Diagnostic Observation Schedule-2 (ADOS-2). The remaining 292 participants had other diagnoses, confirmed after a careful psychiatric evaluation and the administration of the Structured Clinical Interview for DSM-5 (SCID-5). The ASDASQ was administered to contact clinicians of each subject. Results The ASDASQ showed outstanding accuracy (AUC = 0.96) in discriminating between ASD and non-ASD patients, with good sensitivity (0.85) and specificity (0.92). Agreement with clinical diagnosis was substantial (k = 0.68). Internal consistency of the tool was good (Cronbach’s alpha = 0.82), while intra- (ICC = 0.97) and inter-rater reliability (ICC = 0.92) were excellent. We found also a moderate correlation between ASDASQ and ADOS-2 scores in the ASD sample (r = 0.56). Conclusion Our findings suggest that the ASDASQ, in the Italian adaptation, may be considered a quick, simple, and effective tool to screen for ASD among psychiatric outpatients. Further studies are needed to evaluate its utility in other clinical settings. En ligne : https://doi.org/10.1016/j.rasd.2020.101668 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

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