Brief Report: “Allergic Symptoms” in Children with Autism Spectrum Disorders. More than Meets the Eye? / Asimenia ANGELIDOU in Journal of Autism and Developmental Disorders, 41-11 (November 2011)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 41-11 (November 2011) . - p.1579-1585 Titre : Brief Report: “Allergic Symptoms” in Children with Autism Spectrum Disorders. More than Meets the Eye? Type de document : texte imprimé Auteurs : Asimenia ANGELIDOU, Auteur ; Konstantinos-Dionysios ALYSANDRATOS, Auteur ; Shahrzad ASADI, Auteur ; Bodi ZHANG, Auteur ; Konstantinos FRANCIS, Auteur ; Magdalini VASIADI, Auteur ; Dimitrios KALOGEROMITROS, Auteur ; Theoharis THEOHARIDES, Auteur Année de publication : 2011 Article en page(s) : p.1579-1585 Langues : Anglais (eng) Mots-clés : Allergy  Autism  Brain  Food intolerance  Inflammation  Mast cells Index. décimale : PER Périodiques Résumé : Many children with Autism Spectrum Disorders (ASD) have either family and/or personal history of “allergic symptomatology”, often in the absence of positive skin or RAST tests. These symptoms may suggest mast cell activation by non-allergic triggers. Moreover, children with mastocytosis or mast cell activation syndrome (MCAS), a spectrum of rare diseases characterized by increased number of activated mast cells in many organs, appear to have ASD at a rate tenfold higher (1/10 children) than that of the general population (1/100 children). Mast cell activation by allergic, infectious, environmental and stress-related triggers, especially perinatally, would release pro-inflammatory and neurotoxic molecules. We speculate these could disrupt the gut–blood–brain barriers, thus contributing to brain inflammation and ASD pathogenesis. Increased mast cell responsiveness may define at least a subgroup of ASD subjects, who could benefit from inhibition of mast cell activation. En ligne : http://dx.doi.org/10.1007/s10803-010-1171-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=147 [article] Brief Report: “Allergic Symptoms” in Children with Autism Spectrum Disorders. More than Meets the Eye? [texte imprimé] / Asimenia ANGELIDOU, Auteur ; Konstantinos-Dionysios ALYSANDRATOS, Auteur ; Shahrzad ASADI, Auteur ; Bodi ZHANG, Auteur ; Konstantinos FRANCIS, Auteur ; Magdalini VASIADI, Auteur ; Dimitrios KALOGEROMITROS, Auteur ; Theoharis THEOHARIDES, Auteur . - 2011 . - p.1579-1585. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 41-11 (November 2011) . - p.1579-1585 Mots-clés : Allergy  Autism  Brain  Food intolerance  Inflammation  Mast cells Index. décimale : PER Périodiques Résumé : Many children with Autism Spectrum Disorders (ASD) have either family and/or personal history of “allergic symptomatology”, often in the absence of positive skin or RAST tests. These symptoms may suggest mast cell activation by non-allergic triggers. Moreover, children with mastocytosis or mast cell activation syndrome (MCAS), a spectrum of rare diseases characterized by increased number of activated mast cells in many organs, appear to have ASD at a rate tenfold higher (1/10 children) than that of the general population (1/100 children). Mast cell activation by allergic, infectious, environmental and stress-related triggers, especially perinatally, would release pro-inflammatory and neurotoxic molecules. We speculate these could disrupt the gut–blood–brain barriers, thus contributing to brain inflammation and ASD pathogenesis. Increased mast cell responsiveness may define at least a subgroup of ASD subjects, who could benefit from inhibition of mast cell activation. En ligne : http://dx.doi.org/10.1007/s10803-010-1171-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=147

Increased Expression of miR-155p5 in Amygdala of Children With Autism Spectrum Disorder / Khulood Abdullah ALMEHMADI in Autism Research, 13-1 (January 2020)  

Public ISBD [article]  inAutism Research > 13-1 (January 2020) . - p.18-23 Titre : Increased Expression of miR-155p5 in Amygdala of Children With Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Khulood Abdullah ALMEHMADI, Auteur ; Irene TSILIONI, Auteur ; Theoharis C. THEOHARIDES, Auteur Article en page(s) : p.18-23 Langues : Anglais (eng) Mots-clés : Mir-155  autism spectrum disorder  brain  microRNAs  neuroinflammation Index. décimale : PER Périodiques Résumé : MiR-155p5 is a pro-inflammatory microRNA reported to be involved in several neurol-inflammatory diseases. Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by impaired social interactions and communication, as well as stereotypic movements. Inflammation of the brain due to activation of microglia has been reported in ASD. We investigated miR-155p5 gene expression in postmortem human brain tissues [amygdala and dorsolateral prefrontal cortex regions (DLPFC)]. There was significant increase of miR-155p5 in amygdala (P En ligne : http://dx.doi.org/10.1002/aur.2205 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=415 [article] Increased Expression of miR-155p5 in Amygdala of Children With Autism Spectrum Disorder [texte imprimé] / Khulood Abdullah ALMEHMADI, Auteur ; Irene TSILIONI, Auteur ; Theoharis C. THEOHARIDES, Auteur . - p.18-23. Langues : Anglais (eng) in Autism Research > 13-1 (January 2020) . - p.18-23 Mots-clés : Mir-155  autism spectrum disorder  brain  microRNAs  neuroinflammation Index. décimale : PER Périodiques Résumé : MiR-155p5 is a pro-inflammatory microRNA reported to be involved in several neurol-inflammatory diseases. Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by impaired social interactions and communication, as well as stereotypic movements. Inflammation of the brain due to activation of microglia has been reported in ASD. We investigated miR-155p5 gene expression in postmortem human brain tissues [amygdala and dorsolateral prefrontal cortex regions (DLPFC)]. There was significant increase of miR-155p5 in amygdala (P En ligne : http://dx.doi.org/10.1002/aur.2205 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=415

Perinatal Immune Activation and Risk of Autism / Theoharis THEOHARIDES  

Public ISBD in Autism - A Neurodevelopmental Journey from Genes to Behaviour / Valsamma EAPEN   Titre : Perinatal Immune Activation and Risk of Autism Type de document : texte imprimé Auteurs : Theoharis THEOHARIDES, Auteur ; Asimenia ANGELIDOU, Auteur ; Konstantinos-Dionysios ALYSANDRATOS, Auteur ; Shahrzad ASADI, Auteur ; Konstantinos FRANCIS, Auteur ; Lefteris LYKOURAS, Auteur ; Dimitrios KALOGEROMITROS, Auteur Année de publication : 2011 Importance : p.267-288 Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques En ligne : http://dx.doi.org/10.5772/17436 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=143 in Autism - A Neurodevelopmental Journey from Genes to Behaviour / Valsamma EAPEN   Perinatal Immune Activation and Risk of Autism [texte imprimé] / Theoharis THEOHARIDES, Auteur ; Asimenia ANGELIDOU, Auteur ; Konstantinos-Dionysios ALYSANDRATOS, Auteur ; Shahrzad ASADI, Auteur ; Konstantinos FRANCIS, Auteur ; Lefteris LYKOURAS, Auteur ; Dimitrios KALOGEROMITROS, Auteur . - 2011 . - p.267-288. Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques En ligne : http://dx.doi.org/10.5772/17436 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=143

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