Emotional Modulation of Perception in Asperger’s Syndrome / Ben CORDEN in Journal of Autism and Developmental Disorders, 38-6 (July 2008)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 38-6 (July 2008) . - p.1072-1080 Titre : Emotional Modulation of Perception in Asperger’s Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Ben CORDEN, Auteur ; David H. SKUSE, Auteur ; Rebecca CHILVERS, Auteur Année de publication : 2008 Article en page(s) : p.1072-1080 Langues : Anglais (eng) Mots-clés : Social-cognition Amygdala Autism Fear Attentional-blink Emotion Index. décimale : PER Périodiques Résumé : Using an attentional blink paradigm, we show that the typical enhancement of perception for emotionally arousing events is significantly reduced in Asperger’s syndrome (AS) at short inter-target intervals. Control experiments demonstrate that this finding cannot be attributed to differences in the perceived arousal of the stimuli, or to a global impairment affecting any type of modulation of perceptual encoding. Because a functioning amygdala is critical for emotional modulation of the attentional blink, the findings support a role for the amygdala in the pathophysiology of AS. More specifically, they suggest there is a fundamental failure of the amygdala to modulate processing in cortex, a concept at the heart of some recent theories of amygdala involvement in the aetiology of autistic-spectrum disorders. En ligne : http://dx.doi.org/10.1007/s10803-007-0485-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474 [article] Emotional Modulation of Perception in Asperger’s Syndrome [Texte imprimé et/ou numérique] / Ben CORDEN, Auteur ; David H. SKUSE, Auteur ; Rebecca CHILVERS, Auteur . - 2008 . - p.1072-1080. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 38-6 (July 2008) . - p.1072-1080 Mots-clés : Social-cognition Amygdala Autism Fear Attentional-blink Emotion Index. décimale : PER Périodiques Résumé : Using an attentional blink paradigm, we show that the typical enhancement of perception for emotionally arousing events is significantly reduced in Asperger’s syndrome (AS) at short inter-target intervals. Control experiments demonstrate that this finding cannot be attributed to differences in the perceived arousal of the stimuli, or to a global impairment affecting any type of modulation of perceptual encoding. Because a functioning amygdala is critical for emotional modulation of the attentional blink, the findings support a role for the amygdala in the pathophysiology of AS. More specifically, they suggest there is a fundamental failure of the amygdala to modulate processing in cortex, a concept at the heart of some recent theories of amygdala involvement in the aetiology of autistic-spectrum disorders. En ligne : http://dx.doi.org/10.1007/s10803-007-0485-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474

Sex Differences in Autism Spectrum Disorder: Evidence from a Large Sample of Children and Adolescents / William P.L. MANDY in Journal of Autism and Developmental Disorders, 42-7 (July 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1304-1313 Titre : Sex Differences in Autism Spectrum Disorder: Evidence from a Large Sample of Children and Adolescents Type de document : Texte imprimé et/ou numérique Auteurs : William P.L. MANDY, Auteur ; Rebecca CHILVERS, Auteur ; Uttom CHOWDHURY, Auteur ; Gemma SALTER, Auteur ; Anna SEIGAL, Auteur ; David H. SKUSE, Auteur Année de publication : 2012 Article en page(s) : p.1304-1313 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Pervasive developmental disorder  Sex differences  High-functioning  Comorbidity Index. décimale : PER Périodiques Résumé : Sex differences have been found amongst toddlers and young children with autism spectrum disorder (ASD). We investigated the presence and stability of these ASD sex differences throughout childhood and adolescence. Participants (N = 325, 52 females; aged 3–18 years) consecutively received an ASD diagnosis at a clinic for assessing high-functioning ASD (mean verbal IQ = 92.6). There were no IQ sex differences. By parent report and direct observation, females had less repetitive stereotyped behaviour (RSB), with male-equivalent levels of social and communication impairment. Teachers reported males with ASD as having greater externalising and social problems than females. The female phenotype we describe was stable across our sample’s age range. Their milder RSBs and less severe difficulties at school may lead to under-recognition of ASD in females. En ligne : http://dx.doi.org/10.1007/s10803-011-1356-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=165 [article] Sex Differences in Autism Spectrum Disorder: Evidence from a Large Sample of Children and Adolescents [Texte imprimé et/ou numérique] / William P.L. MANDY, Auteur ; Rebecca CHILVERS, Auteur ; Uttom CHOWDHURY, Auteur ; Gemma SALTER, Auteur ; Anna SEIGAL, Auteur ; David H. SKUSE, Auteur . - 2012 . - p.1304-1313. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1304-1313 Mots-clés : Autism spectrum disorder  Pervasive developmental disorder  Sex differences  High-functioning  Comorbidity Index. décimale : PER Périodiques Résumé : Sex differences have been found amongst toddlers and young children with autism spectrum disorder (ASD). We investigated the presence and stability of these ASD sex differences throughout childhood and adolescence. Participants (N = 325, 52 females; aged 3–18 years) consecutively received an ASD diagnosis at a clinic for assessing high-functioning ASD (mean verbal IQ = 92.6). There were no IQ sex differences. By parent report and direct observation, females had less repetitive stereotyped behaviour (RSB), with male-equivalent levels of social and communication impairment. Teachers reported males with ASD as having greater externalising and social problems than females. The female phenotype we describe was stable across our sample’s age range. Their milder RSBs and less severe difficulties at school may lead to under-recognition of ASD in females. En ligne : http://dx.doi.org/10.1007/s10803-011-1356-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=165

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