138 recherche sur le mot-clé 'Sex differences'

Sex Differences in Autism Spectrum Disorder: Evidence from a Large Sample of Children and Adolescents / William P.L. MANDY in Journal of Autism and Developmental Disorders, 42-7 (July 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1304-1313 Titre : Sex Differences in Autism Spectrum Disorder: Evidence from a Large Sample of Children and Adolescents Type de document : Texte imprimé et/ou numérique Auteurs : William P.L. MANDY, Auteur ; Rebecca CHILVERS, Auteur ; Uttom CHOWDHURY, Auteur ; Gemma SALTER, Auteur ; Anna SEIGAL, Auteur ; David H. SKUSE, Auteur Année de publication : 2012 Article en page(s) : p.1304-1313 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Pervasive developmental disorder  Sex differences  High-functioning  Comorbidity Index. décimale : PER Périodiques Résumé : Sex differences have been found amongst toddlers and young children with autism spectrum disorder (ASD). We investigated the presence and stability of these ASD sex differences throughout childhood and adolescence. Participants (N = 325, 52 females; aged 3–18 years) consecutively received an ASD diagnosis at a clinic for assessing high-functioning ASD (mean verbal IQ = 92.6). There were no IQ sex differences. By parent report and direct observation, females had less repetitive stereotyped behaviour (RSB), with male-equivalent levels of social and communication impairment. Teachers reported males with ASD as having greater externalising and social problems than females. The female phenotype we describe was stable across our sample’s age range. Their milder RSBs and less severe difficulties at school may lead to under-recognition of ASD in females. En ligne : http://dx.doi.org/10.1007/s10803-011-1356-0 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1659 [article] Sex Differences in Autism Spectrum Disorder: Evidence from a Large Sample of Children and Adolescents [Texte imprimé et/ou numérique] / William P.L. MANDY, Auteur ; Rebecca CHILVERS, Auteur ; Uttom CHOWDHURY, Auteur ; Gemma SALTER, Auteur ; Anna SEIGAL, Auteur ; David H. SKUSE, Auteur . - 2012 . - p.1304-1313. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1304-1313 Mots-clés : Autism spectrum disorder  Pervasive developmental disorder  Sex differences  High-functioning  Comorbidity Index. décimale : PER Périodiques Résumé : Sex differences have been found amongst toddlers and young children with autism spectrum disorder (ASD). We investigated the presence and stability of these ASD sex differences throughout childhood and adolescence. Participants (N = 325, 52 females; aged 3–18 years) consecutively received an ASD diagnosis at a clinic for assessing high-functioning ASD (mean verbal IQ = 92.6). There were no IQ sex differences. By parent report and direct observation, females had less repetitive stereotyped behaviour (RSB), with male-equivalent levels of social and communication impairment. Teachers reported males with ASD as having greater externalising and social problems than females. The female phenotype we describe was stable across our sample’s age range. Their milder RSBs and less severe difficulties at school may lead to under-recognition of ASD in females. En ligne : http://dx.doi.org/10.1007/s10803-011-1356-0 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1659

Sex Differences in Children with Autism Spectrum Disorder Identified Within a High-Risk Infant Cohort / Lonnie ZWAIGENBAUM in Journal of Autism and Developmental Disorders, 42-12 (December 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-12 (December 2012) . - p.2585-2596 Titre : Sex Differences in Children with Autism Spectrum Disorder Identified Within a High-Risk Infant Cohort Type de document : Texte imprimé et/ou numérique Auteurs : Lonnie ZWAIGENBAUM, Auteur ; Susan E. BRYSON, Auteur ; Peter SZATMARI, Auteur ; Jessica BRIAN, Auteur ; Isabel M. SMITH, Auteur ; Wendy ROBERTS, Auteur ; Tracy VAILLANCOURT, Auteur ; Caroline RONCADIN, Auteur Article en page(s) : p.2585-2596 Langues : Anglais (eng) Mots-clés : Autism  Early diagnosis  Sex differences  Infants  Longitudinal study Index. décimale : PER Périodiques Résumé : Sex differences were examined in 3-year-olds with autism spectrum disorders (ASD) ascertained from a high-risk cohort, and high- and low-risk comparison groups. Participants included 319 high-risk siblings and 129 low-risk controls. Eighty-five siblings were diagnosed with ASD, including 57 of 176 boys (32.4 %) and 28 of 143 girls (19.6 %), implying a relative odds of ASD of 1.65 in boys versus girls. There were modest sex differences on cognitive and adaptive skills and ASD symptom severity at age 3, but differences between boys and girls with ASD mirrored those in the non-ASD groups. The lower than expected male-to-female ratio, and the relatively high cognitive level among diagnosed children, suggest that we have identified an unanticipated number of higher-functioning girls with ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1515-y Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1846 [article] Sex Differences in Children with Autism Spectrum Disorder Identified Within a High-Risk Infant Cohort [Texte imprimé et/ou numérique] / Lonnie ZWAIGENBAUM, Auteur ; Susan E. BRYSON, Auteur ; Peter SZATMARI, Auteur ; Jessica BRIAN, Auteur ; Isabel M. SMITH, Auteur ; Wendy ROBERTS, Auteur ; Tracy VAILLANCOURT, Auteur ; Caroline RONCADIN, Auteur . - p.2585-2596. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-12 (December 2012) . - p.2585-2596 Mots-clés : Autism  Early diagnosis  Sex differences  Infants  Longitudinal study Index. décimale : PER Périodiques Résumé : Sex differences were examined in 3-year-olds with autism spectrum disorders (ASD) ascertained from a high-risk cohort, and high- and low-risk comparison groups. Participants included 319 high-risk siblings and 129 low-risk controls. Eighty-five siblings were diagnosed with ASD, including 57 of 176 boys (32.4 %) and 28 of 143 girls (19.6 %), implying a relative odds of ASD of 1.65 in boys versus girls. There were modest sex differences on cognitive and adaptive skills and ASD symptom severity at age 3, but differences between boys and girls with ASD mirrored those in the non-ASD groups. The lower than expected male-to-female ratio, and the relatively high cognitive level among diagnosed children, suggest that we have identified an unanticipated number of higher-functioning girls with ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1515-y Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1846

Sex differences in age of diagnosis of autism spectrum disorder: Preliminary evidence from Uganda / E. BONNEY in Autism Research, 15-1 (January 2022)  

Public ISBD [article]  inAutism Research > 15-1 (January 2022) . - p.183-191 Titre : Sex differences in age of diagnosis of autism spectrum disorder: Preliminary evidence from Uganda Type de document : Texte imprimé et/ou numérique Auteurs : E. BONNEY, Auteur ; C. ABBO, Auteur ; C. OGARA, Auteur ; M. E. VILLALOBOS, Auteur ; J. T. ELISON, Auteur Article en page(s) : p.183-191 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis/epidemiology  Blacks  Child  Child, Preschool  Female  Humans  Male  Retrospective Studies  Sex Characteristics  Uganda/epidemiology  Africa  Uganda  age of diagnosis  autism spectrum disorder  sex differences Index. décimale : PER Périodiques Résumé : This study was performed to determine (a) the age at which autism spectrum disorder (ASD) is first diagnosed in Ugandan children receiving mental health services, (b) whether age at diagnosis varies by sex and clinical presentation, and (c) the average age of ASD diagnosis in children manifesting comorbid conditions. A retrospective chart review was performed and demographic as well as clinical data were collected from children with ASD diagnoses who attended two mental health clinics in Uganda between 2014 and 2019. Descriptive statistics such as percentages, means, and standard deviations were used to summarize the data. Independent t-test was also performed to determine differences in the mean age of diagnosis between males and females. Two hundred and thirty-seven (156 males, 81 females) children with ASD were identified. The average age of ASD diagnosis was (6.9?±?4.0)?years. A statistically significant difference in age of ASD diagnosis was found between males and females (t = -2.106, p = 0.036), such that on average females received a diagnosis at least 1?year later than males. Of the 237 participants, 53.6% were identified with ASD only, 16.0% had ASD and ADHD, 10.5% were diagnosed with ASD and epilepsy, and 7.2% had a diagnosis of complex ASD. The results confirm delays in access to ASD diagnosis and suggest that females are more likely to receive a ASD diagnosis later than males within the Ugandan context. ASD awareness should be intensified to improve public or professional knowledge about ASD to enhance early identification in Uganda. En ligne : http://dx.doi.org/10.1002/aur.2645 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4508 [article] Sex differences in age of diagnosis of autism spectrum disorder: Preliminary evidence from Uganda [Texte imprimé et/ou numérique] / E. BONNEY, Auteur ; C. ABBO, Auteur ; C. OGARA, Auteur ; M. E. VILLALOBOS, Auteur ; J. T. ELISON, Auteur . - p.183-191. Langues : Anglais (eng) in Autism Research > 15-1 (January 2022) . - p.183-191 Mots-clés : Autism Spectrum Disorder/diagnosis/epidemiology  Blacks  Child  Child, Preschool  Female  Humans  Male  Retrospective Studies  Sex Characteristics  Uganda/epidemiology  Africa  Uganda  age of diagnosis  autism spectrum disorder  sex differences Index. décimale : PER Périodiques Résumé : This study was performed to determine (a) the age at which autism spectrum disorder (ASD) is first diagnosed in Ugandan children receiving mental health services, (b) whether age at diagnosis varies by sex and clinical presentation, and (c) the average age of ASD diagnosis in children manifesting comorbid conditions. A retrospective chart review was performed and demographic as well as clinical data were collected from children with ASD diagnoses who attended two mental health clinics in Uganda between 2014 and 2019. Descriptive statistics such as percentages, means, and standard deviations were used to summarize the data. Independent t-test was also performed to determine differences in the mean age of diagnosis between males and females. Two hundred and thirty-seven (156 males, 81 females) children with ASD were identified. The average age of ASD diagnosis was (6.9?±?4.0)?years. A statistically significant difference in age of ASD diagnosis was found between males and females (t = -2.106, p = 0.036), such that on average females received a diagnosis at least 1?year later than males. Of the 237 participants, 53.6% were identified with ASD only, 16.0% had ASD and ADHD, 10.5% were diagnosed with ASD and epilepsy, and 7.2% had a diagnosis of complex ASD. The results confirm delays in access to ASD diagnosis and suggest that females are more likely to receive a ASD diagnosis later than males within the Ugandan context. ASD awareness should be intensified to improve public or professional knowledge about ASD to enhance early identification in Uganda. En ligne : http://dx.doi.org/10.1002/aur.2645 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4508

Sex differences in Arab children with Autism spectrum disorders / Mostafa AMR in Research in Autism Spectrum Disorders, 5-4 (October-December 2011)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 5-4 (October-December 2011) . - p.1343-1350 Titre : Sex differences in Arab children with Autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Mostafa AMR, Auteur ; Dahoud RADDAD, Auteur ; Fatima EL-MEHESH, Auteur ; Mahmoud EL-HASSANIN, Auteur ; Abdel-Hady EL-GILANY, Auteur Année de publication : 2011 Article en page(s) : p.1343-1350 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Sex differences  Children  Autistic symptoms  Behavior problems Index. décimale : PER Périodiques Résumé : Although autism spectrum disorders (ASD) prevalence is higher in males than females in Arab countries, few studies address sex differences in autistic symptoms and coexiting behavioral problems. A total of 37 boys and 23 girls recruited from three Arab countries (Egypt, Saudi Arabia, Jordan) matched for age and IQ. They were compared using Indian Scale for Assessment of Autism (ISAA) and the Child Behavior Checklist (CBCL). The boys had poor emotional responsiveness and the girls had more cognitive problems. With regard to coexisting psychopathology boys exhibited significantly more delinquent behavior problems. Longitudinal, representative studies are needed to elucidate etiological significance of the observed sex differences. En ligne : http://dx.doi.org/10.1016/j.rasd.2011.01.015 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1258 [article] Sex differences in Arab children with Autism spectrum disorders [Texte imprimé et/ou numérique] / Mostafa AMR, Auteur ; Dahoud RADDAD, Auteur ; Fatima EL-MEHESH, Auteur ; Mahmoud EL-HASSANIN, Auteur ; Abdel-Hady EL-GILANY, Auteur . - 2011 . - p.1343-1350. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 5-4 (October-December 2011) . - p.1343-1350 Mots-clés : Autism spectrum disorder  Sex differences  Children  Autistic symptoms  Behavior problems Index. décimale : PER Périodiques Résumé : Although autism spectrum disorders (ASD) prevalence is higher in males than females in Arab countries, few studies address sex differences in autistic symptoms and coexiting behavioral problems. A total of 37 boys and 23 girls recruited from three Arab countries (Egypt, Saudi Arabia, Jordan) matched for age and IQ. They were compared using Indian Scale for Assessment of Autism (ISAA) and the Child Behavior Checklist (CBCL). The boys had poor emotional responsiveness and the girls had more cognitive problems. With regard to coexisting psychopathology boys exhibited significantly more delinquent behavior problems. Longitudinal, representative studies are needed to elucidate etiological significance of the observed sex differences. En ligne : http://dx.doi.org/10.1016/j.rasd.2011.01.015 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1258

Sex differences in brain structure: a twin study on restricted and repetitive behaviors in twin pairs with and without autism / A. VAN'T WESTEINDE in Molecular Autism, 11 (2020)  

Public ISBD [article]  inMolecular Autism > 11 (2020) . - 1 p. Titre : Sex differences in brain structure: a twin study on restricted and repetitive behaviors in twin pairs with and without autism Type de document : Texte imprimé et/ou numérique Auteurs : A. VAN'T WESTEINDE, Auteur ; Elodie CAUVET, Auteur ; R. TORO, Auteur ; R. KUJA-HALKOLA, Auteur ; J. NEUFELD, Auteur ; K. MEVEL, Auteur ; Sven BÖLTE, Auteur Article en page(s) : 1 p. Langues : Anglais (eng) Mots-clés : Autism  Neuroanatomy  Repetitive behaviors  Sex differences  Twins Index. décimale : PER Périodiques Résumé : Background: Females with autism spectrum disorder have been reported to exhibit fewer and less severe restricted and repetitive behaviors and interests compared to males. This difference might indicate sex-specific alterations of brain networks involved in autism symptom domains, especially within cortico-striatal and sensory integration networks. This study used a well-controlled twin design to examine sex differences in brain anatomy in relation to repetitive behaviors. Methods: In 75 twin pairs (n = 150, 62 females, 88 males) enriched for autism spectrum disorder (n = 32), and other neurodevelopmental disorders (n = 32), we explored the association of restricted and repetitive behaviors and interests-operationalized by the Autism Diagnostic Interview-Revised (C domain) and the Social Responsiveness Scale-2 (Restricted Interests and Repetitive Behavior subscale)-with cortical volume, surface area and thickness of neocortical, sub-cortical, and cerebellar networks. Results: Co-twin control analyses revealed within-pair associations between RRBI symptoms and increased thickness of the right intraparietal sulcus and reduced volume of the right orbital gyrus in females only, even though the mean number of RRBIs did not differ between the sexes. In a sub-sample of ASD-discordant pairs, increased thickness in association with RRBIs was found exclusively in females in the orbitofrontal regions, superior frontal gyrus, and intraparietal sulcus, while in males RRBIs tended to be associated with increased volume of the bilateral pallidum. Limitations: However, due to a small sample size and the small difference in RRBI symptoms within pairs, the results of this exploratory study need to be interpreted with caution. Conclusions: Our findings suggest that structural alterations of fronto-parietal networks in association with RRBIs are found mostly in females, while striatal networks are more affected in males. These results endorse the importance of investigating sex differences in the neurobiology of autism symptoms, and indicate different etiological pathways underlying restricted and repetitive behaviors and interests in females and males. En ligne : http://dx.doi.org/10.1186/s13229-019-0309-x Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4146 [article] Sex differences in brain structure: a twin study on restricted and repetitive behaviors in twin pairs with and without autism [Texte imprimé et/ou numérique] / A. VAN'T WESTEINDE, Auteur ; Elodie CAUVET, Auteur ; R. TORO, Auteur ; R. KUJA-HALKOLA, Auteur ; J. NEUFELD, Auteur ; K. MEVEL, Auteur ; Sven BÖLTE, Auteur . - 1 p. Langues : Anglais (eng) in Molecular Autism > 11 (2020) . - 1 p. Mots-clés : Autism  Neuroanatomy  Repetitive behaviors  Sex differences  Twins Index. décimale : PER Périodiques Résumé : Background: Females with autism spectrum disorder have been reported to exhibit fewer and less severe restricted and repetitive behaviors and interests compared to males. This difference might indicate sex-specific alterations of brain networks involved in autism symptom domains, especially within cortico-striatal and sensory integration networks. This study used a well-controlled twin design to examine sex differences in brain anatomy in relation to repetitive behaviors. Methods: In 75 twin pairs (n = 150, 62 females, 88 males) enriched for autism spectrum disorder (n = 32), and other neurodevelopmental disorders (n = 32), we explored the association of restricted and repetitive behaviors and interests-operationalized by the Autism Diagnostic Interview-Revised (C domain) and the Social Responsiveness Scale-2 (Restricted Interests and Repetitive Behavior subscale)-with cortical volume, surface area and thickness of neocortical, sub-cortical, and cerebellar networks. Results: Co-twin control analyses revealed within-pair associations between RRBI symptoms and increased thickness of the right intraparietal sulcus and reduced volume of the right orbital gyrus in females only, even though the mean number of RRBIs did not differ between the sexes. In a sub-sample of ASD-discordant pairs, increased thickness in association with RRBIs was found exclusively in females in the orbitofrontal regions, superior frontal gyrus, and intraparietal sulcus, while in males RRBIs tended to be associated with increased volume of the bilateral pallidum. Limitations: However, due to a small sample size and the small difference in RRBI symptoms within pairs, the results of this exploratory study need to be interpreted with caution. Conclusions: Our findings suggest that structural alterations of fronto-parietal networks in association with RRBIs are found mostly in females, while striatal networks are more affected in males. These results endorse the importance of investigating sex differences in the neurobiology of autism symptoms, and indicate different etiological pathways underlying restricted and repetitive behaviors and interests in females and males. En ligne : http://dx.doi.org/10.1186/s13229-019-0309-x Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4146

Sex differences in cognitive and symptom profiles in children with high functioning autism spectrum disorders / Hirokazu KUMAZAKI in Research in Autism Spectrum Disorders, 13-14 (May 2015)  

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Sex differences in employment and supports for adults with autism spectrum disorder / Julie LOUNDS TAYLOR in Autism, 23-7 (October 2019)  

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Sex Differences in Externalizing and Internalizing Symptoms of Children with ASD / Brian C. NASCA in Journal of Autism and Developmental Disorders, 50-9 (September 2020)  

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Sex differences in foetal origins of child emotional symptoms: a test of evolutionary hypotheses in a large, general population cohort / Elizabeth C. BRAITHWAITE in Journal of Child Psychology and Psychiatry, 61-11 (November 2020)  

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Sex Differences in Gender-Diverse Expressions and Identities among Youth with Autism Spectrum Disorder / Ludivine BRUNISSEN in Autism Research, 14-1 (January 2021)  

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