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Sex Differences in Autism Spectrum Disorder: Evidence from a Large Sample of Children and Adolescents / William P.L. MANDY in Journal of Autism and Developmental Disorders, 42-7 (July 2012)
[article]
Titre : Sex Differences in Autism Spectrum Disorder: Evidence from a Large Sample of Children and Adolescents Type de document : Texte imprimé et/ou numérique Auteurs : William P.L. MANDY, Auteur ; Rebecca CHILVERS, Auteur ; Uttom CHOWDHURY, Auteur ; Gemma SALTER, Auteur ; Anna SEIGAL, Auteur ; David H. SKUSE, Auteur Année de publication : 2012 Article en page(s) : p.1304-1313 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Pervasive developmental disorder Sex differences High-functioning Comorbidity Index. décimale : PER Périodiques Résumé : Sex differences have been found amongst toddlers and young children with autism spectrum disorder (ASD). We investigated the presence and stability of these ASD sex differences throughout childhood and adolescence. Participants (N = 325, 52 females; aged 3–18 years) consecutively received an ASD diagnosis at a clinic for assessing high-functioning ASD (mean verbal IQ = 92.6). There were no IQ sex differences. By parent report and direct observation, females had less repetitive stereotyped behaviour (RSB), with male-equivalent levels of social and communication impairment. Teachers reported males with ASD as having greater externalising and social problems than females. The female phenotype we describe was stable across our sample’s age range. Their milder RSBs and less severe difficulties at school may lead to under-recognition of ASD in females. En ligne : http://dx.doi.org/10.1007/s10803-011-1356-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=165
in Journal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1304-1313[article] Sex Differences in Autism Spectrum Disorder: Evidence from a Large Sample of Children and Adolescents [Texte imprimé et/ou numérique] / William P.L. MANDY, Auteur ; Rebecca CHILVERS, Auteur ; Uttom CHOWDHURY, Auteur ; Gemma SALTER, Auteur ; Anna SEIGAL, Auteur ; David H. SKUSE, Auteur . - 2012 . - p.1304-1313.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1304-1313
Mots-clés : Autism spectrum disorder Pervasive developmental disorder Sex differences High-functioning Comorbidity Index. décimale : PER Périodiques Résumé : Sex differences have been found amongst toddlers and young children with autism spectrum disorder (ASD). We investigated the presence and stability of these ASD sex differences throughout childhood and adolescence. Participants (N = 325, 52 females; aged 3–18 years) consecutively received an ASD diagnosis at a clinic for assessing high-functioning ASD (mean verbal IQ = 92.6). There were no IQ sex differences. By parent report and direct observation, females had less repetitive stereotyped behaviour (RSB), with male-equivalent levels of social and communication impairment. Teachers reported males with ASD as having greater externalising and social problems than females. The female phenotype we describe was stable across our sample’s age range. Their milder RSBs and less severe difficulties at school may lead to under-recognition of ASD in females. En ligne : http://dx.doi.org/10.1007/s10803-011-1356-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=165 Sex Differences in Children with Autism Spectrum Disorder Identified Within a High-Risk Infant Cohort / Lonnie ZWAIGENBAUM in Journal of Autism and Developmental Disorders, 42-12 (December 2012)
[article]
Titre : Sex Differences in Children with Autism Spectrum Disorder Identified Within a High-Risk Infant Cohort Type de document : Texte imprimé et/ou numérique Auteurs : Lonnie ZWAIGENBAUM, Auteur ; Susan E. BRYSON, Auteur ; Peter SZATMARI, Auteur ; Jessica BRIAN, Auteur ; Isabel M. SMITH, Auteur ; Wendy ROBERTS, Auteur ; Tracy VAILLANCOURT, Auteur ; Caroline RONCADIN, Auteur Article en page(s) : p.2585-2596 Langues : Anglais (eng) Mots-clés : Autism Early diagnosis Sex differences Infants Longitudinal study Index. décimale : PER Périodiques Résumé : Sex differences were examined in 3-year-olds with autism spectrum disorders (ASD) ascertained from a high-risk cohort, and high- and low-risk comparison groups. Participants included 319 high-risk siblings and 129 low-risk controls. Eighty-five siblings were diagnosed with ASD, including 57 of 176 boys (32.4 %) and 28 of 143 girls (19.6 %), implying a relative odds of ASD of 1.65 in boys versus girls. There were modest sex differences on cognitive and adaptive skills and ASD symptom severity at age 3, but differences between boys and girls with ASD mirrored those in the non-ASD groups. The lower than expected male-to-female ratio, and the relatively high cognitive level among diagnosed children, suggest that we have identified an unanticipated number of higher-functioning girls with ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1515-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=184
in Journal of Autism and Developmental Disorders > 42-12 (December 2012) . - p.2585-2596[article] Sex Differences in Children with Autism Spectrum Disorder Identified Within a High-Risk Infant Cohort [Texte imprimé et/ou numérique] / Lonnie ZWAIGENBAUM, Auteur ; Susan E. BRYSON, Auteur ; Peter SZATMARI, Auteur ; Jessica BRIAN, Auteur ; Isabel M. SMITH, Auteur ; Wendy ROBERTS, Auteur ; Tracy VAILLANCOURT, Auteur ; Caroline RONCADIN, Auteur . - p.2585-2596.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-12 (December 2012) . - p.2585-2596
Mots-clés : Autism Early diagnosis Sex differences Infants Longitudinal study Index. décimale : PER Périodiques Résumé : Sex differences were examined in 3-year-olds with autism spectrum disorders (ASD) ascertained from a high-risk cohort, and high- and low-risk comparison groups. Participants included 319 high-risk siblings and 129 low-risk controls. Eighty-five siblings were diagnosed with ASD, including 57 of 176 boys (32.4 %) and 28 of 143 girls (19.6 %), implying a relative odds of ASD of 1.65 in boys versus girls. There were modest sex differences on cognitive and adaptive skills and ASD symptom severity at age 3, but differences between boys and girls with ASD mirrored those in the non-ASD groups. The lower than expected male-to-female ratio, and the relatively high cognitive level among diagnosed children, suggest that we have identified an unanticipated number of higher-functioning girls with ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1515-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=184 Sex differences in age of diagnosis of autism spectrum disorder: Preliminary evidence from Uganda / E. BONNEY in Autism Research, 15-1 (January 2022)
[article]
Titre : Sex differences in age of diagnosis of autism spectrum disorder: Preliminary evidence from Uganda Type de document : Texte imprimé et/ou numérique Auteurs : E. BONNEY, Auteur ; C. ABBO, Auteur ; C. OGARA, Auteur ; M. E. VILLALOBOS, Auteur ; J. T. ELISON, Auteur Article en page(s) : p.183-191 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis/epidemiology Blacks Child Child, Preschool Female Humans Male Retrospective Studies Sex Characteristics Uganda/epidemiology Africa Uganda age of diagnosis autism spectrum disorder sex differences Index. décimale : PER Périodiques Résumé : This study was performed to determine (a) the age at which autism spectrum disorder (ASD) is first diagnosed in Ugandan children receiving mental health services, (b) whether age at diagnosis varies by sex and clinical presentation, and (c) the average age of ASD diagnosis in children manifesting comorbid conditions. A retrospective chart review was performed and demographic as well as clinical data were collected from children with ASD diagnoses who attended two mental health clinics in Uganda between 2014 and 2019. Descriptive statistics such as percentages, means, and standard deviations were used to summarize the data. Independent t-test was also performed to determine differences in the mean age of diagnosis between males and females. Two hundred and thirty-seven (156 males, 81 females) children with ASD were identified. The average age of ASD diagnosis was (6.9?±?4.0)?years. A statistically significant difference in age of ASD diagnosis was found between males and females (t = -2.106, p = 0.036), such that on average females received a diagnosis at least 1?year later than males. Of the 237 participants, 53.6% were identified with ASD only, 16.0% had ASD and ADHD, 10.5% were diagnosed with ASD and epilepsy, and 7.2% had a diagnosis of complex ASD. The results confirm delays in access to ASD diagnosis and suggest that females are more likely to receive a ASD diagnosis later than males within the Ugandan context. ASD awareness should be intensified to improve public or professional knowledge about ASD to enhance early identification in Uganda. En ligne : http://dx.doi.org/10.1002/aur.2645 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450
in Autism Research > 15-1 (January 2022) . - p.183-191[article] Sex differences in age of diagnosis of autism spectrum disorder: Preliminary evidence from Uganda [Texte imprimé et/ou numérique] / E. BONNEY, Auteur ; C. ABBO, Auteur ; C. OGARA, Auteur ; M. E. VILLALOBOS, Auteur ; J. T. ELISON, Auteur . - p.183-191.
Langues : Anglais (eng)
in Autism Research > 15-1 (January 2022) . - p.183-191
Mots-clés : Autism Spectrum Disorder/diagnosis/epidemiology Blacks Child Child, Preschool Female Humans Male Retrospective Studies Sex Characteristics Uganda/epidemiology Africa Uganda age of diagnosis autism spectrum disorder sex differences Index. décimale : PER Périodiques Résumé : This study was performed to determine (a) the age at which autism spectrum disorder (ASD) is first diagnosed in Ugandan children receiving mental health services, (b) whether age at diagnosis varies by sex and clinical presentation, and (c) the average age of ASD diagnosis in children manifesting comorbid conditions. A retrospective chart review was performed and demographic as well as clinical data were collected from children with ASD diagnoses who attended two mental health clinics in Uganda between 2014 and 2019. Descriptive statistics such as percentages, means, and standard deviations were used to summarize the data. Independent t-test was also performed to determine differences in the mean age of diagnosis between males and females. Two hundred and thirty-seven (156 males, 81 females) children with ASD were identified. The average age of ASD diagnosis was (6.9?±?4.0)?years. A statistically significant difference in age of ASD diagnosis was found between males and females (t = -2.106, p = 0.036), such that on average females received a diagnosis at least 1?year later than males. Of the 237 participants, 53.6% were identified with ASD only, 16.0% had ASD and ADHD, 10.5% were diagnosed with ASD and epilepsy, and 7.2% had a diagnosis of complex ASD. The results confirm delays in access to ASD diagnosis and suggest that females are more likely to receive a ASD diagnosis later than males within the Ugandan context. ASD awareness should be intensified to improve public or professional knowledge about ASD to enhance early identification in Uganda. En ligne : http://dx.doi.org/10.1002/aur.2645 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 Sex differences in Arab children with Autism spectrum disorders / Mostafa AMR in Research in Autism Spectrum Disorders, 5-4 (October-December 2011)
[article]
Titre : Sex differences in Arab children with Autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Mostafa AMR, Auteur ; Dahoud RADDAD, Auteur ; Fatima EL-MEHESH, Auteur ; Mahmoud EL-HASSANIN, Auteur ; Abdel-Hady EL-GILANY, Auteur Année de publication : 2011 Article en page(s) : p.1343-1350 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Sex differences Children Autistic symptoms Behavior problems Index. décimale : PER Périodiques Résumé : Although autism spectrum disorders (ASD) prevalence is higher in males than females in Arab countries, few studies address sex differences in autistic symptoms and coexiting behavioral problems. A total of 37 boys and 23 girls recruited from three Arab countries (Egypt, Saudi Arabia, Jordan) matched for age and IQ. They were compared using Indian Scale for Assessment of Autism (ISAA) and the Child Behavior Checklist (CBCL). The boys had poor emotional responsiveness and the girls had more cognitive problems. With regard to coexisting psychopathology boys exhibited significantly more delinquent behavior problems. Longitudinal, representative studies are needed to elucidate etiological significance of the observed sex differences. En ligne : http://dx.doi.org/10.1016/j.rasd.2011.01.015 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=125
in Research in Autism Spectrum Disorders > 5-4 (October-December 2011) . - p.1343-1350[article] Sex differences in Arab children with Autism spectrum disorders [Texte imprimé et/ou numérique] / Mostafa AMR, Auteur ; Dahoud RADDAD, Auteur ; Fatima EL-MEHESH, Auteur ; Mahmoud EL-HASSANIN, Auteur ; Abdel-Hady EL-GILANY, Auteur . - 2011 . - p.1343-1350.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 5-4 (October-December 2011) . - p.1343-1350
Mots-clés : Autism spectrum disorder Sex differences Children Autistic symptoms Behavior problems Index. décimale : PER Périodiques Résumé : Although autism spectrum disorders (ASD) prevalence is higher in males than females in Arab countries, few studies address sex differences in autistic symptoms and coexiting behavioral problems. A total of 37 boys and 23 girls recruited from three Arab countries (Egypt, Saudi Arabia, Jordan) matched for age and IQ. They were compared using Indian Scale for Assessment of Autism (ISAA) and the Child Behavior Checklist (CBCL). The boys had poor emotional responsiveness and the girls had more cognitive problems. With regard to coexisting psychopathology boys exhibited significantly more delinquent behavior problems. Longitudinal, representative studies are needed to elucidate etiological significance of the observed sex differences. En ligne : http://dx.doi.org/10.1016/j.rasd.2011.01.015 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=125 Sex differences in attention-deficit hyperactivity disorder diagnosis and clinical care: a national study of population healthcare records in Wales / Joanna MARTIN in Journal of Child Psychology and Psychiatry, 65-12 (December 2024)
[article]
Titre : Sex differences in attention-deficit hyperactivity disorder diagnosis and clinical care: a national study of population healthcare records in Wales Type de document : Texte imprimé et/ou numérique Auteurs : Joanna MARTIN, Auteur ; Kate LANGLEY, Auteur ; Miriam COOPER, Auteur ; Olivier Y. ROUQUETTE, Auteur ; Ann JOHN, Auteur ; Kapil SAYAL, Auteur ; Tamsin FORD, Auteur ; Anita THAPAR, Auteur Article en page(s) : p.1648-1658 Langues : Anglais (eng) Mots-clés : ADHD sex differences neurodevelopmental conditions mental health Index. décimale : PER Périodiques Résumé : Background Population-based studies have observed sex biases in the diagnosis and treatment of attention-deficit hyperactivity disorder (ADHD). Females are less likely to be diagnosed or prescribed ADHD medication. This study uses national healthcare records, to investigate sex differences in diagnosis and clinical care in young people with ADHD, particularly regarding recognition and treatment of other mental health conditions. Methods The cohort included individuals diagnosed with ADHD, born between 1989 and 2013 and living in Wales between 2000 and 2019. Routine primary and secondary healthcare record data were used to derive diagnoses of ADHD and other neurodevelopmental and mental health conditions, as well as ADHD and antidepressant medications. Demographic variables included ethnicity, socioeconomic deprivation and contact with social services. Results There were 16,458 individuals diagnosed with ADHD (20.3% females, ages 3?30?years), with a male-to-female ratio of 3.9:1. Higher ratios (4.8:1) were seen in individuals diagnosed younger (<12?years), with the lowest ratio (1.9:1) in those diagnosed as adults (>18). Males were younger at first recorded ADHD diagnosis (mean?=?10.9 vs. 12.6?years), more likely to be prescribed ADHD medication and younger at diagnosis of co-occurring neurodevelopmental conditions. In contrast, females were more likely to receive a diagnosis of anxiety, depression or another mental health condition and to be prescribed antidepressant medications, prior to ADHD diagnosis. These sex differences were largely stable across demographic groups. Conclusions This study adds to the evidence base that females with ADHD are experiencing later recognition and treatment of ADHD. The results indicate that this may be partly because of diagnostic overshadowing from other mental health conditions, such as anxiety and depression, or initial misdiagnosis. Further research and dissemination of findings to the public are needed to improve awareness, timely diagnosis and treatment of ADHD in females. En ligne : https://doi.org/10.1111/jcpp.13987 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Journal of Child Psychology and Psychiatry > 65-12 (December 2024) . - p.1648-1658[article] Sex differences in attention-deficit hyperactivity disorder diagnosis and clinical care: a national study of population healthcare records in Wales [Texte imprimé et/ou numérique] / Joanna MARTIN, Auteur ; Kate LANGLEY, Auteur ; Miriam COOPER, Auteur ; Olivier Y. ROUQUETTE, Auteur ; Ann JOHN, Auteur ; Kapil SAYAL, Auteur ; Tamsin FORD, Auteur ; Anita THAPAR, Auteur . - p.1648-1658.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 65-12 (December 2024) . - p.1648-1658
Mots-clés : ADHD sex differences neurodevelopmental conditions mental health Index. décimale : PER Périodiques Résumé : Background Population-based studies have observed sex biases in the diagnosis and treatment of attention-deficit hyperactivity disorder (ADHD). Females are less likely to be diagnosed or prescribed ADHD medication. This study uses national healthcare records, to investigate sex differences in diagnosis and clinical care in young people with ADHD, particularly regarding recognition and treatment of other mental health conditions. Methods The cohort included individuals diagnosed with ADHD, born between 1989 and 2013 and living in Wales between 2000 and 2019. Routine primary and secondary healthcare record data were used to derive diagnoses of ADHD and other neurodevelopmental and mental health conditions, as well as ADHD and antidepressant medications. Demographic variables included ethnicity, socioeconomic deprivation and contact with social services. Results There were 16,458 individuals diagnosed with ADHD (20.3% females, ages 3?30?years), with a male-to-female ratio of 3.9:1. Higher ratios (4.8:1) were seen in individuals diagnosed younger (<12?years), with the lowest ratio (1.9:1) in those diagnosed as adults (>18). Males were younger at first recorded ADHD diagnosis (mean?=?10.9 vs. 12.6?years), more likely to be prescribed ADHD medication and younger at diagnosis of co-occurring neurodevelopmental conditions. In contrast, females were more likely to receive a diagnosis of anxiety, depression or another mental health condition and to be prescribed antidepressant medications, prior to ADHD diagnosis. These sex differences were largely stable across demographic groups. Conclusions This study adds to the evidence base that females with ADHD are experiencing later recognition and treatment of ADHD. The results indicate that this may be partly because of diagnostic overshadowing from other mental health conditions, such as anxiety and depression, or initial misdiagnosis. Further research and dissemination of findings to the public are needed to improve awareness, timely diagnosis and treatment of ADHD in females. En ligne : https://doi.org/10.1111/jcpp.13987 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542 Sex differences in autism screening: An examination of the Childhood Autism Spectrum Test-Hebrew version / Michael TERNER in Autism, 28-10 (October 2024)
PermalinkSex differences in brain structure: a twin study on restricted and repetitive behaviors in twin pairs with and without autism / A. VAN'T WESTEINDE in Molecular Autism, 11 (2020)
PermalinkSex differences in cognitive and symptom profiles in children with high functioning autism spectrum disorders / Hirokazu KUMAZAKI in Research in Autism Spectrum Disorders, 13-14 (May 2015)
PermalinkSex differences in early autism screening using the Modified Checklist for Autism in Toddlers, Revised, with Follow-Up (M-CHAT-R/F) / Sherief Y ELDEEB in Autism, 27-7 (October 2023)
PermalinkSex differences in employment and supports for adults with autism spectrum disorder / Julie LOUNDS TAYLOR in Autism, 23-7 (October 2019)
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