Comparison of Serum VEGF, IGF-1, and HIF-1? Levels in Children with Autism Spectrum Disorder and Healthy Controls / F. ?IM?EK in Journal of Autism and Developmental Disorders, 51-10 (October 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-10 (October 2021) . - p.3564-3574 Titre : Comparison of Serum VEGF, IGF-1, and HIF-1? Levels in Children with Autism Spectrum Disorder and Healthy Controls Type de document : Texte imprimé et/ou numérique Auteurs : F. ?IM?EK, Auteur ; Ü I?IK, Auteur ; E. AKTEPE, Auteur ; F. KILIÇ, Auteur ; F. B. ?IRIN, Auteur ; M. BOZKURT, Auteur Article en page(s) : p.3564-3574 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis  Child  Humans  Hypoxia-Inducible Factor 1, alpha Subunit/blood  Insulin-Like Growth Factor I/analysis  Vascular Endothelial Growth Factor A/blood  Autism spectrum disorder  Hif-1?  Igf-1  Vegf Index. décimale : PER Périodiques Résumé : The aim of this study was to determine whether serum VEGF, IGF-1, and HIF-1? levels differed between Autism Spectrum Disorder (ASD) patients and healthy controls. A total of 40 children with ASD and 40 healthy controls aged 4-12 years were included. Serum levels of VEGF, IGF-1, and HIF-1? were measured using commercial enzyme-linked immunosorbent assay kits. Serum IGF-1 levels were found to be statistically significantly higher in the ASD group than in the control group. Serum HIF-1? levels were borderline significantly lower in the ASD group. There was no statistically significant difference in serum VEGF levels between the two groups. IGF-1 and HIF-1? may play a potential role in the etiopathogenesis of ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04820-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453 [article] Comparison of Serum VEGF, IGF-1, and HIF-1? Levels in Children with Autism Spectrum Disorder and Healthy Controls [Texte imprimé et/ou numérique] / F. ?IM?EK, Auteur ; Ü I?IK, Auteur ; E. AKTEPE, Auteur ; F. KILIÇ, Auteur ; F. B. ?IRIN, Auteur ; M. BOZKURT, Auteur . - p.3564-3574. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-10 (October 2021) . - p.3564-3574 Mots-clés : Autism Spectrum Disorder/diagnosis  Child  Humans  Hypoxia-Inducible Factor 1, alpha Subunit/blood  Insulin-Like Growth Factor I/analysis  Vascular Endothelial Growth Factor A/blood  Autism spectrum disorder  Hif-1?  Igf-1  Vegf Index. décimale : PER Périodiques Résumé : The aim of this study was to determine whether serum VEGF, IGF-1, and HIF-1? levels differed between Autism Spectrum Disorder (ASD) patients and healthy controls. A total of 40 children with ASD and 40 healthy controls aged 4-12 years were included. Serum levels of VEGF, IGF-1, and HIF-1? were measured using commercial enzyme-linked immunosorbent assay kits. Serum IGF-1 levels were found to be statistically significantly higher in the ASD group than in the control group. Serum HIF-1? levels were borderline significantly lower in the ASD group. There was no statistically significant difference in serum VEGF levels between the two groups. IGF-1 and HIF-1? may play a potential role in the etiopathogenesis of ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04820-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453

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