Decreased Cortical Thickness in the Anterior Cingulate Cortex in Adults with Autism / Charles LAIDI in Journal of Autism and Developmental Disorders, 49-4 (April 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-4 (April 2019) . - p.1402-1409 Titre : Decreased Cortical Thickness in the Anterior Cingulate Cortex in Adults with Autism Type de document : texte imprimé Auteurs : Charles LAIDI, Auteur ; Jennifer BOISGONTIER, Auteur ; Amicie DE PIERREFEU, Auteur ; Edouard DUCHESNAY, Auteur ; Sevan HOTIER, Auteur ; Marc-Antoine D'ALBIS, Auteur ; Richard DELORME, Auteur ; Federico BOLOGNANI, Auteur ; Christian CZECH, Auteur ; Céline BOUQUET, Auteur ; Anouck AMESTOY, Auteur ; Julie PETIT, Auteur ; Stefan HOLIGA, Auteur ; Juergen DUKART, Auteur ; Alexandru GAMAN, Auteur ; Elie TOLEDANO, Auteur ; Myriam Ly LE-MOAL, Auteur ; Isabelle SCHEID, Auteur ; Marion LEBOYER, Auteur ; Josselin HOUENOU, Auteur Article en page(s) : p.1402-1409 Langues : Anglais (eng) Mots-clés : Adults  Anterior cingulate cortex  Autism  Mri Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a developmental disorder underdiagnosed in adults. To date, no consistent evidence of alterations in brain structure has been reported in adults with ASD and few studies were conducted at that age. We analyzed structural magnetic resonance imaging data from 167 high functioning adults with ASD and 195 controls. We ran our analyses on a discovery (n = 301) and a replication sample (n = 61). The right caudal anterior cingulate cortical thickness was significantly thinner in adults with ASD compared to controls in both the discovery and the replication sample. Our work underlines the relevance of studying the brain anatomy of an adult ASD population. En ligne : https://dx.doi.org/10.1007/s10803-018-3807-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388 [article] Decreased Cortical Thickness in the Anterior Cingulate Cortex in Adults with Autism [texte imprimé] / Charles LAIDI, Auteur ; Jennifer BOISGONTIER, Auteur ; Amicie DE PIERREFEU, Auteur ; Edouard DUCHESNAY, Auteur ; Sevan HOTIER, Auteur ; Marc-Antoine D'ALBIS, Auteur ; Richard DELORME, Auteur ; Federico BOLOGNANI, Auteur ; Christian CZECH, Auteur ; Céline BOUQUET, Auteur ; Anouck AMESTOY, Auteur ; Julie PETIT, Auteur ; Stefan HOLIGA, Auteur ; Juergen DUKART, Auteur ; Alexandru GAMAN, Auteur ; Elie TOLEDANO, Auteur ; Myriam Ly LE-MOAL, Auteur ; Isabelle SCHEID, Auteur ; Marion LEBOYER, Auteur ; Josselin HOUENOU, Auteur . - p.1402-1409. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-4 (April 2019) . - p.1402-1409 Mots-clés : Adults  Anterior cingulate cortex  Autism  Mri Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a developmental disorder underdiagnosed in adults. To date, no consistent evidence of alterations in brain structure has been reported in adults with ASD and few studies were conducted at that age. We analyzed structural magnetic resonance imaging data from 167 high functioning adults with ASD and 195 controls. We ran our analyses on a discovery (n = 301) and a replication sample (n = 61). The right caudal anterior cingulate cortical thickness was significantly thinner in adults with ASD compared to controls in both the discovery and the replication sample. Our work underlines the relevance of studying the brain anatomy of an adult ASD population. En ligne : https://dx.doi.org/10.1007/s10803-018-3807-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388

Preserved navigation abilities and spatio-temporal memory in individuals with autism spectrum disorder / Nathan NEU ; Aurélie WATILLIAUX ; Axelle MARTINEZ-TERUEL ; Mihoby RAZAFINIMANANA ; Jennifer BOISGONTIER ; Sevan HOTIER ; Marc-Antoine D'ALBIS ; Richard DELORME ; Anouck AMESTOY ; Stefan HOLIGA ; Myriam Ly LE-MOAL ; Pierrick COUPÃ ; Marion LEBOYER ; Josselin HOUENOU ; Laure RONDI-REIG ; Anne-Lise PARADIS in Autism Research, 16-2 (February 2023)  

Public ISBD [article]  inAutism Research > 16-2 (February 2023) . - p.280-293 Titre : Preserved navigation abilities and spatio-temporal memory in individuals with autism spectrum disorder Type de document : texte imprimé Auteurs : Nathan NEU, Auteur ; Aurélie WATILLIAUX, Auteur ; Axelle MARTINEZ-TERUEL, Auteur ; Mihoby RAZAFINIMANANA, Auteur ; Jennifer BOISGONTIER, Auteur ; Sevan HOTIER, Auteur ; Marc-Antoine D'ALBIS, Auteur ; Richard DELORME, Auteur ; Anouck AMESTOY, Auteur ; Stefan HOLIGA, Auteur ; Myriam Ly LE-MOAL, Auteur ; Pierrick COUPÃ, Auteur ; Marion LEBOYER, Auteur ; Josselin HOUENOU, Auteur ; Laure RONDI-REIG, Auteur ; Anne-Lise PARADIS, Auteur Article en page(s) : p.280-293 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Cerebellar abnormalities have been reported in autism spectrum disorder (ASD). Beyond its role in hallmark features of ASD, the cerebellum and its connectivity with forebrain structures also play a role in navigation. However, the current understanding of navigation abilities in ASD is equivocal, as is the impact of the disorder on the functional anatomy of the cerebellum. In the present study, we investigated the navigation behavior of a population of ASD and typically developing (TD) adults related to their brain anatomy as assessed by structural and functional MRI at rest. We used the Starmaze task, which permits assessing and distinguishing two complex navigation behaviors, one based on allocentric learning and the other on egocentric learning of a route with multiple decision points. Compared to TD controls, individuals with ASD showed similar exploration, learning, and strategy performance and preference. In addition, there was no difference in the structural or functional anatomy of the cerebellar circuits involved in navigation between the two groups. The findings of our work suggest that navigation abilities, spatio-temporal memory, and their underlying circuits are preserved in individuals with ASD. En ligne : https://doi.org/10.1002/aur.2865 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=495 [article] Preserved navigation abilities and spatio-temporal memory in individuals with autism spectrum disorder [texte imprimé] / Nathan NEU, Auteur ; Aurélie WATILLIAUX, Auteur ; Axelle MARTINEZ-TERUEL, Auteur ; Mihoby RAZAFINIMANANA, Auteur ; Jennifer BOISGONTIER, Auteur ; Sevan HOTIER, Auteur ; Marc-Antoine D'ALBIS, Auteur ; Richard DELORME, Auteur ; Anouck AMESTOY, Auteur ; Stefan HOLIGA, Auteur ; Myriam Ly LE-MOAL, Auteur ; Pierrick COUPÃ, Auteur ; Marion LEBOYER, Auteur ; Josselin HOUENOU, Auteur ; Laure RONDI-REIG, Auteur ; Anne-Lise PARADIS, Auteur . - p.280-293. Langues : Anglais (eng) in Autism Research > 16-2 (February 2023) . - p.280-293 Index. décimale : PER Périodiques Résumé : Abstract Cerebellar abnormalities have been reported in autism spectrum disorder (ASD). Beyond its role in hallmark features of ASD, the cerebellum and its connectivity with forebrain structures also play a role in navigation. However, the current understanding of navigation abilities in ASD is equivocal, as is the impact of the disorder on the functional anatomy of the cerebellum. In the present study, we investigated the navigation behavior of a population of ASD and typically developing (TD) adults related to their brain anatomy as assessed by structural and functional MRI at rest. We used the Starmaze task, which permits assessing and distinguishing two complex navigation behaviors, one based on allocentric learning and the other on egocentric learning of a route with multiple decision points. Compared to TD controls, individuals with ASD showed similar exploration, learning, and strategy performance and preference. In addition, there was no difference in the structural or functional anatomy of the cerebellar circuits involved in navigation between the two groups. The findings of our work suggest that navigation abilities, spatio-temporal memory, and their underlying circuits are preserved in individuals with ASD. En ligne : https://doi.org/10.1002/aur.2865 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=495

---

1 (1 - 2 / 2) Par page : 25 50 100 200