Cognitive predictors of Social processing in congenital atypical development / Elisabetta FERRARI in Journal of Autism and Developmental Disorders, 53-9 (September 2023)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 53-9 (September 2023) . - p.3343-3355 Titre : Cognitive predictors of Social processing in congenital atypical development Type de document : Texte imprimé et/ou numérique Auteurs : Elisabetta FERRARI, Auteur ; Niccolò BUTTI, Auteur ; Chiara GAGLIARDI, Auteur ; Romina ROMANIELLO, Auteur ; Renato BORGATTI, Auteur ; Cosimo URGESI, Auteur Article en page(s) : p.3343-3355 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : According to current accounts of social cognition, the emergence of verbal and non-verbal components of social perception might rely on the acquisition of different cognitive abilities. These components might be differently sensitive to the pattern of neuropsychological impairments in congenital neurodevelopmental disorders. Here, we explored the association between social and non-social cognitive domains by administering subtests of the NEPSY-II battery to 92 patients with Intellectual and Developmental Disability (IDD). Regardless the level of intellectual functioning and presence of congenital brain malformations, results revealed that visuospatial skills predicted emotion recognition and verbal component of Theory of Mind, whereas imitation predicted the non-verbal one. Future interventions might focus on spatial and sensorimotor abilities to boost the development of social cognition in IDD. En ligne : https://doi.org/10.1007/s10803-022-05630-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511 [article] Cognitive predictors of Social processing in congenital atypical development [Texte imprimé et/ou numérique] / Elisabetta FERRARI, Auteur ; Niccolò BUTTI, Auteur ; Chiara GAGLIARDI, Auteur ; Romina ROMANIELLO, Auteur ; Renato BORGATTI, Auteur ; Cosimo URGESI, Auteur . - p.3343-3355. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 53-9 (September 2023) . - p.3343-3355 Index. décimale : PER Périodiques Résumé : According to current accounts of social cognition, the emergence of verbal and non-verbal components of social perception might rely on the acquisition of different cognitive abilities. These components might be differently sensitive to the pattern of neuropsychological impairments in congenital neurodevelopmental disorders. Here, we explored the association between social and non-social cognitive domains by administering subtests of the NEPSY-II battery to 92 patients with Intellectual and Developmental Disability (IDD). Regardless the level of intellectual functioning and presence of congenital brain malformations, results revealed that visuospatial skills predicted emotion recognition and verbal component of Theory of Mind, whereas imitation predicted the non-verbal one. Future interventions might focus on spatial and sensorimotor abilities to boost the development of social cognition in IDD. En ligne : https://doi.org/10.1007/s10803-022-05630-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=511

Feasibility and Efficacy of a Virtual Reality Social Prediction Training in Children and Young Adults with Congenital Cerebellar Malformations / Emilia BIFFI ; Romina ROMANIELLO ; Alessandra FINISGUERRA ; Enza Maria VALENTE ; Sandra STRAZZER ; Renato BORGATTI ; Cosimo URGESI in Journal of Autism and Developmental Disorders, 55-7 (July 2025)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 55-7 (July 2025) . - p.2463-2479 Titre : Feasibility and Efficacy of a Virtual Reality Social Prediction Training in Children and Young Adults with Congenital Cerebellar Malformations Type de document : Texte imprimé et/ou numérique Auteurs : Emilia BIFFI, Auteur ; Romina ROMANIELLO, Auteur ; Alessandra FINISGUERRA, Auteur ; Enza Maria VALENTE, Auteur ; Sandra STRAZZER, Auteur ; Renato BORGATTI, Auteur ; Cosimo URGESI, Auteur Article en page(s) : p.2463-2479 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : This study tested the feasibility and efficacy of a Virtual Reality (VR) social prediction training (VR-Spirit) specifically designed for patients with congenital cerebellar malformation. The study is a randomised controlled trial in which 28 cerebellar patients aged 7-25 yo were randomly allocated to the VR-Spirit or to a control intervention in VR. The VR-Spirit required participants to compete with different avatars in scenarios that prompted them to form predictions about avatars" intentions. The control intervention consisted of games currently adopted for motor rehabilitation. Social prediction as well as secondary neuropsychological and behavioural outcomes were assessed at the beginning (T0), at the end (T2) and after 2 months (T3). The experimental group showed a significant increase, compared to the control participants, in social prediction assessed through a VR task. Moreover, at least at T3, the VR-Spirit enhanced the use of contextual predictions in a computer-based action prediction task. Importantly, these effects were generalized to secondary neuropsychological outcomes, specifically theory of mind and, only at T2, inhibition. No differences between the interventions were detected on emotional-behavioural problems. Lastly, both interventions showed high feasibility and acceptability. These findings confirm that it is possible to develop condition-specific rehabilitative training on the basis of neurocognitive functions impaired in case of congenital malformation. The VR-Spirit demonstrated to generalize its effects to theory of mind abilities, and it might be thus extended to other neurodevelopmental disorders that present social perception deficits and alterations of predictive processing. En ligne : https://doi.org/10.1007/s10803-024-06349-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559 [article] Feasibility and Efficacy of a Virtual Reality Social Prediction Training in Children and Young Adults with Congenital Cerebellar Malformations [Texte imprimé et/ou numérique] / Emilia BIFFI, Auteur ; Romina ROMANIELLO, Auteur ; Alessandra FINISGUERRA, Auteur ; Enza Maria VALENTE, Auteur ; Sandra STRAZZER, Auteur ; Renato BORGATTI, Auteur ; Cosimo URGESI, Auteur . - p.2463-2479. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 55-7 (July 2025) . - p.2463-2479 Index. décimale : PER Périodiques Résumé : This study tested the feasibility and efficacy of a Virtual Reality (VR) social prediction training (VR-Spirit) specifically designed for patients with congenital cerebellar malformation. The study is a randomised controlled trial in which 28 cerebellar patients aged 7-25 yo were randomly allocated to the VR-Spirit or to a control intervention in VR. The VR-Spirit required participants to compete with different avatars in scenarios that prompted them to form predictions about avatars" intentions. The control intervention consisted of games currently adopted for motor rehabilitation. Social prediction as well as secondary neuropsychological and behavioural outcomes were assessed at the beginning (T0), at the end (T2) and after 2 months (T3). The experimental group showed a significant increase, compared to the control participants, in social prediction assessed through a VR task. Moreover, at least at T3, the VR-Spirit enhanced the use of contextual predictions in a computer-based action prediction task. Importantly, these effects were generalized to secondary neuropsychological outcomes, specifically theory of mind and, only at T2, inhibition. No differences between the interventions were detected on emotional-behavioural problems. Lastly, both interventions showed high feasibility and acceptability. These findings confirm that it is possible to develop condition-specific rehabilitative training on the basis of neurocognitive functions impaired in case of congenital malformation. The VR-Spirit demonstrated to generalize its effects to theory of mind abilities, and it might be thus extended to other neurodevelopmental disorders that present social perception deficits and alterations of predictive processing. En ligne : https://doi.org/10.1007/s10803-024-06349-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=559

Prenatal maternal stress during the COVID-19 pandemic and infant regulatory capacity at 3 months: A longitudinal study / Livio PROVENZI in Development and Psychopathology, 35-1 (February 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-1 (February 2023) . - p.35-43 Titre : Prenatal maternal stress during the COVID-19 pandemic and infant regulatory capacity at 3 months: A longitudinal study Type de document : Texte imprimé et/ou numérique Auteurs : Livio PROVENZI, Auteur ; Serena GRUMI, Auteur ; Lilia ALTIERI, Auteur ; Giulia BENSI, Auteur ; Emanuela BERTAZZOLI, Auteur ; Giacomo BIASUCCI, Auteur ; Anna CAVALLINI, Auteur ; Lidia DECEMBRINO, Auteur ; Rossana FALCONE, Auteur ; Anna FREDDI, Auteur ; Barbara GARDELLA, Auteur ; Roberta GIACCHERO, Auteur ; Roberto GIORDA, Auteur ; Elena GROSSI, Auteur ; Paola GUERINI, Auteur ; Maria Luisa MAGNANI, Auteur ; Paola MARTELLI, Auteur ; Mario MOTTA, Auteur ; Renata NACINOVICH, Auteur ; Dario PANTALEO, Auteur ; Camilla PISONI, Auteur ; Federico PREFUMO, Auteur ; Laura RIVA, Auteur ; Barbara SCELSA, Auteur ; Maria V. SPARTÀ, Auteur ; Arsenio SPINILLO, Auteur ; Patrizia VERGANI, Auteur ; Simona ORCESI, Auteur ; Renato BORGATTI, Auteur Article en page(s) : p.35-43 Langues : Anglais (eng) Mots-clés : anxiety  COVID-19  epidemic  maternal bonding  prenatal stress  regulatory capacity  social support  temperament Index. décimale : PER Périodiques Résumé : The COVID-19 pandemic is a global traumatic experience for citizens, especially during sensitive time windows of heightened plasticity such as pregnancy and neonatal life. Pandemic-related stress experienced by mothers during pregnancy may act as an early risk factor for infants' regulatory capacity development by altering maternal psychosocial well-being (e.g., increased anxiety, reduced social support) and caregiving environment (e.g., greater parenting stress, impaired mother-infant bonding). The aim of the present longitudinal study was to assess the consequences of pandemic-related prenatal stress on infants' regulatory capacity. A sample of 163 mother-infant dyads was enrolled at eight maternity units in northern Italy. They provided complete data about prenatal stress, perceived social support, postnatal anxiety symptoms, parenting stress, mother-infant bonding, and infants' regulatory capacity at 3 months of age. Women who experienced emotional stress and received partial social support during pregnancy reported higher anxious symptoms. Moreover, maternal postnatal anxiety was indirectly linked to the infants' regulatory capacity at 3 months, mediated by parenting stress and mother-infant bonding. Dedicated preventive interventions should be delivered to mothers and should be focused on protecting the mother-infant dyad from the detrimental effects of pandemic-related stress during the COVID-19 healthcare emergency. En ligne : https://doi.org/10.1017/S0954579421000766 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499 [article] Prenatal maternal stress during the COVID-19 pandemic and infant regulatory capacity at 3 months: A longitudinal study [Texte imprimé et/ou numérique] / Livio PROVENZI, Auteur ; Serena GRUMI, Auteur ; Lilia ALTIERI, Auteur ; Giulia BENSI, Auteur ; Emanuela BERTAZZOLI, Auteur ; Giacomo BIASUCCI, Auteur ; Anna CAVALLINI, Auteur ; Lidia DECEMBRINO, Auteur ; Rossana FALCONE, Auteur ; Anna FREDDI, Auteur ; Barbara GARDELLA, Auteur ; Roberta GIACCHERO, Auteur ; Roberto GIORDA, Auteur ; Elena GROSSI, Auteur ; Paola GUERINI, Auteur ; Maria Luisa MAGNANI, Auteur ; Paola MARTELLI, Auteur ; Mario MOTTA, Auteur ; Renata NACINOVICH, Auteur ; Dario PANTALEO, Auteur ; Camilla PISONI, Auteur ; Federico PREFUMO, Auteur ; Laura RIVA, Auteur ; Barbara SCELSA, Auteur ; Maria V. SPARTÀ, Auteur ; Arsenio SPINILLO, Auteur ; Patrizia VERGANI, Auteur ; Simona ORCESI, Auteur ; Renato BORGATTI, Auteur . - p.35-43. Langues : Anglais (eng) in Development and Psychopathology > 35-1 (February 2023) . - p.35-43 Mots-clés : anxiety  COVID-19  epidemic  maternal bonding  prenatal stress  regulatory capacity  social support  temperament Index. décimale : PER Périodiques Résumé : The COVID-19 pandemic is a global traumatic experience for citizens, especially during sensitive time windows of heightened plasticity such as pregnancy and neonatal life. Pandemic-related stress experienced by mothers during pregnancy may act as an early risk factor for infants' regulatory capacity development by altering maternal psychosocial well-being (e.g., increased anxiety, reduced social support) and caregiving environment (e.g., greater parenting stress, impaired mother-infant bonding). The aim of the present longitudinal study was to assess the consequences of pandemic-related prenatal stress on infants' regulatory capacity. A sample of 163 mother-infant dyads was enrolled at eight maternity units in northern Italy. They provided complete data about prenatal stress, perceived social support, postnatal anxiety symptoms, parenting stress, mother-infant bonding, and infants' regulatory capacity at 3 months of age. Women who experienced emotional stress and received partial social support during pregnancy reported higher anxious symptoms. Moreover, maternal postnatal anxiety was indirectly linked to the infants' regulatory capacity at 3 months, mediated by parenting stress and mother-infant bonding. Dedicated preventive interventions should be delivered to mothers and should be focused on protecting the mother-infant dyad from the detrimental effects of pandemic-related stress during the COVID-19 healthcare emergency. En ligne : https://doi.org/10.1017/S0954579421000766 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499

Sex-dimorphic pathways in the associations between maternal trait anxiety, infant BDNF methylation, and negative emotionality / Serena GRUMI ; Fabiana MAMBRETTI ; Marco VILLA ; Roberto GIORDA ; Matteo BORDONI ; Orietta PANSARASA ; Renato BORGATTI ; Livio PROVENZI in Development and Psychopathology, 36-2 (May 2024)  

Public ISBD [article]  inDevelopment and Psychopathology > 36-2 (May 2024) . - p.908-918 Titre : Sex-dimorphic pathways in the associations between maternal trait anxiety, infant BDNF methylation, and negative emotionality Type de document : Texte imprimé et/ou numérique Auteurs : Serena GRUMI, Auteur ; Fabiana MAMBRETTI, Auteur ; Marco VILLA, Auteur ; Roberto GIORDA, Auteur ; Matteo BORDONI, Auteur ; Orietta PANSARASA, Auteur ; Renato BORGATTI, Auteur ; Livio PROVENZI, Auteur Article en page(s) : p.908-918 Langues : Anglais (eng) Mots-clés : Anxiety  Brain-derived neurotrophic factor  Methylation  Pregnancy  Temperament Index. décimale : PER Périodiques Résumé : Maternal antenatal anxiety is an emerging risk factor for child emotional development. Both sex and epigenetic mechanisms, such as DNA methylation, may contribute to the embedding of maternal distress into emotional outcomes. Here, we investigated sex-dependent patterns in the association between antenatal maternal trait anxiety, methylation of the brain-derived neurotrophic factor gene (BDNF DNAm), and infant negative emotionality (NE). Mother-infant dyads (N = 276) were recruited at delivery. Maternal trait anxiety, as a marker of antenatal chronic stress exposure, was assessed soon after delivery using the Stait-Trait Anxiety Inventory (STAI-Y). Infants' BDNF DNAm at birth was assessed in 11 CpG sites in buccal cells whereas infants' NE was assessed at 3 (N = 225) and 6 months (N = 189) using the Infant Behavior Questionnaire-Revised (IBQ-R). Hierarchical linear analyses showed that higher maternal antenatal anxiety was associated with greater 6-month-olds' NE. Furthermore, maternal antenatal anxiety predicted greater infants' BDNF DNAm in five CpG sites in males but not in females. Higher methylation at these sites was associated with greater 3-to-6-month NE increase, independently of infants' sex. Maternal antenatal anxiety emerged as a risk factor for infant?s NE. BDNF DNAm might mediate this effect in males. These results may inform the development of strategies to promote mothers and infants' emotional well-being. En ligne : https://dx.doi.org/10.1017/S0954579423000172 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=528 [article] Sex-dimorphic pathways in the associations between maternal trait anxiety, infant BDNF methylation, and negative emotionality [Texte imprimé et/ou numérique] / Serena GRUMI, Auteur ; Fabiana MAMBRETTI, Auteur ; Marco VILLA, Auteur ; Roberto GIORDA, Auteur ; Matteo BORDONI, Auteur ; Orietta PANSARASA, Auteur ; Renato BORGATTI, Auteur ; Livio PROVENZI, Auteur . - p.908-918. Langues : Anglais (eng) in Development and Psychopathology > 36-2 (May 2024) . - p.908-918 Mots-clés : Anxiety  Brain-derived neurotrophic factor  Methylation  Pregnancy  Temperament Index. décimale : PER Périodiques Résumé : Maternal antenatal anxiety is an emerging risk factor for child emotional development. Both sex and epigenetic mechanisms, such as DNA methylation, may contribute to the embedding of maternal distress into emotional outcomes. Here, we investigated sex-dependent patterns in the association between antenatal maternal trait anxiety, methylation of the brain-derived neurotrophic factor gene (BDNF DNAm), and infant negative emotionality (NE). Mother-infant dyads (N = 276) were recruited at delivery. Maternal trait anxiety, as a marker of antenatal chronic stress exposure, was assessed soon after delivery using the Stait-Trait Anxiety Inventory (STAI-Y). Infants' BDNF DNAm at birth was assessed in 11 CpG sites in buccal cells whereas infants' NE was assessed at 3 (N = 225) and 6 months (N = 189) using the Infant Behavior Questionnaire-Revised (IBQ-R). Hierarchical linear analyses showed that higher maternal antenatal anxiety was associated with greater 6-month-olds' NE. Furthermore, maternal antenatal anxiety predicted greater infants' BDNF DNAm in five CpG sites in males but not in females. Higher methylation at these sites was associated with greater 3-to-6-month NE increase, independently of infants' sex. Maternal antenatal anxiety emerged as a risk factor for infant?s NE. BDNF DNAm might mediate this effect in males. These results may inform the development of strategies to promote mothers and infants' emotional well-being. En ligne : https://dx.doi.org/10.1017/S0954579423000172 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=528

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