Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Détail de l'auteur
Auteur Li CAI |
Documents disponibles écrits par cet auteur (1)
Faire une suggestion Affiner la recherche
Associations of unintended pregnancy with autism spectrum disorders and the modification of folic acid supplements / Xing-Lian LIU ; Li-Zi LIN ; Xin WANG ; Ming-Hui LI ; Mei-Xia DAI ; Mu-Qing CAO ; Xiu-Hong LI ; Jing JIN ; Hai-Qing XU ; Li CAI in Autism Research, 17-1 (January 2024)
[article]
Titre : Associations of unintended pregnancy with autism spectrum disorders and the modification of folic acid supplements Type de document : Texte imprimé et/ou numérique Auteurs : Xing-Lian LIU, Auteur ; Li-Zi LIN, Auteur ; Xin WANG, Auteur ; Ming-Hui LI, Auteur ; Mei-Xia DAI, Auteur ; Mu-Qing CAO, Auteur ; Xiu-Hong LI, Auteur ; Jing JIN, Auteur ; Hai-Qing XU, Auteur ; Li CAI, Auteur Article en page(s) : p.172-181 Index. décimale : PER Périodiques Résumé : Abstract There is limited evidence on the associations of unintended pregnancy with autism spectrum disorders (ASD). This study aimed to examine this relationship and the modification of pre-conceptional and prenatal folic acid supplements. Six thousand and five toddlers aged 16 to 30?months from seven cities of six provinces in China were eligible for participation. Information on unintended pregnancy and folic acid supplements was obtained via questionnaires from caregivers of toddlers. The diagnosis of ASD was based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and the Chinese version of the Childhood Autism Rating Scale (CARS). Of the 6005 toddlers in the study (3337 boys and 2668 girls), 71 (1.18%) received the diagnosis of ASD. Generalized linear models with a logit link function showed unintended pregnancy was positively associated with ASD (odds ratios [OR]?=?1.69, 95% confidence interval [CI], 1.05?2.79). Stratified estimates indicated that the association remained stable among toddlers of mothers without pre-conceptional and prenatal folic acid supplements (OR?=?2.75, 95% CI, 1.04?7.27; n?=?1243, 20.70%). Unintended pregnancy was associated with higher odds of ASD in 16?30?months of toddlers, and the association was consistent among toddlers of mothers without prenatal folic acid supplements. Our findings emphasize the need to raise awareness of the risk of unintended pregnancy and the benefits of folic acid supplements among Chinese women. En ligne : https://doi.org/10.1002/aur.3070 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=519
in Autism Research > 17-1 (January 2024) . - p.172-181[article] Associations of unintended pregnancy with autism spectrum disorders and the modification of folic acid supplements [Texte imprimé et/ou numérique] / Xing-Lian LIU, Auteur ; Li-Zi LIN, Auteur ; Xin WANG, Auteur ; Ming-Hui LI, Auteur ; Mei-Xia DAI, Auteur ; Mu-Qing CAO, Auteur ; Xiu-Hong LI, Auteur ; Jing JIN, Auteur ; Hai-Qing XU, Auteur ; Li CAI, Auteur . - p.172-181.
in Autism Research > 17-1 (January 2024) . - p.172-181
Index. décimale : PER Périodiques Résumé : Abstract There is limited evidence on the associations of unintended pregnancy with autism spectrum disorders (ASD). This study aimed to examine this relationship and the modification of pre-conceptional and prenatal folic acid supplements. Six thousand and five toddlers aged 16 to 30?months from seven cities of six provinces in China were eligible for participation. Information on unintended pregnancy and folic acid supplements was obtained via questionnaires from caregivers of toddlers. The diagnosis of ASD was based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and the Chinese version of the Childhood Autism Rating Scale (CARS). Of the 6005 toddlers in the study (3337 boys and 2668 girls), 71 (1.18%) received the diagnosis of ASD. Generalized linear models with a logit link function showed unintended pregnancy was positively associated with ASD (odds ratios [OR]?=?1.69, 95% confidence interval [CI], 1.05?2.79). Stratified estimates indicated that the association remained stable among toddlers of mothers without pre-conceptional and prenatal folic acid supplements (OR?=?2.75, 95% CI, 1.04?7.27; n?=?1243, 20.70%). Unintended pregnancy was associated with higher odds of ASD in 16?30?months of toddlers, and the association was consistent among toddlers of mothers without prenatal folic acid supplements. Our findings emphasize the need to raise awareness of the risk of unintended pregnancy and the benefits of folic acid supplements among Chinese women. En ligne : https://doi.org/10.1002/aur.3070 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=519