Associations of maternal peripregnancy cannabis use with behavioral and developmental outcomes in children with and without symptoms of autism spectrum disorder: Study to Explore Early Development / Carolyn G. DIGUISEPPI ; Tessa CRUME ; Brady HOLST ; Kaylynn AIONA ; Julia VAN DYKE ; Lisa A. CROEN ; Julie L. DANIELS ; Sandra FRIEDMAN ; Katherine R. SABOURIN ; Laura A. SCHIEVE ; Lisa WIGGINS ; Gayle C. WINDHAM ; Cordelia ROBINSON ROSENBERG in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.202-216 Titre : Associations of maternal peripregnancy cannabis use with behavioral and developmental outcomes in children with and without symptoms of autism spectrum disorder: Study to Explore Early Development : Autism Research Type de document : texte imprimé Auteurs : Carolyn G. DIGUISEPPI, Auteur ; Tessa CRUME, Auteur ; Brady HOLST, Auteur ; Kaylynn AIONA, Auteur ; Julia VAN DYKE, Auteur ; Lisa A. CROEN, Auteur ; Julie L. DANIELS, Auteur ; Sandra FRIEDMAN, Auteur ; Katherine R. SABOURIN, Auteur ; Laura A. SCHIEVE, Auteur ; Lisa WIGGINS, Auteur ; Gayle C. WINDHAM, Auteur ; Cordelia ROBINSON ROSENBERG, Auteur Article en page(s) : p.202-216 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  cannabis  child behavior  child preschool  developmental disabilities  pregnancy  prenatal risk factors  sleep wake disorders Index. décimale : PER Périodiques Résumé : Abstract Some studies report increased prevalence of autism spectrum disorder (ASD) and associated symptoms with prenatal cannabis exposure. We examined whether associations of maternal cannabis use from 3 months preconception through delivery (?peripregnancy?) with behavior and development in the offspring varied with the presence of ASD symptoms. Children ages 30 68 months with ASD symptoms (i.e., met study criteria for ASD or had ASD symptoms on standardized assessments or community ASD diagnosis, N 2734) and without ASD symptoms (other developmental delay/disorders or general population sample, N 3454) were evaluated with the Child Behavior Checklist and Mullen Scales of Early Learning. We examined cannabis use during three time periods: peripregnancy, pregnancy, and only preconception. Peripregnancy cannabis exposure was reported for 6.0% of children with and 4.6% of children without ASD symptoms. Preconception-only cannabis use (versus no use) was associated with more aggressive behavior, emotional reactivity, and sleep problems in children with ASD symptoms, but not in children without ASD symptoms. Cannabis use during pregnancy was associated with increased attention and sleep problems in children with ASD symptoms; these associations did not differ significantly by ASD symptoms. Peripregnancy cannabis use was not associated with child developmental abilities regardless of ASD symptoms. In summary, associations of peripregnancy cannabis use with some behavioral outcomes differed in children with and without ASD symptoms. With rising cannabis use among pregnant women, future studies that examine a range of developmental risks associated with timing and patterns of cannabis use prior to conception as well as during pregnancy could inform clinical guidance. En ligne : https://doi.org/10.1002/aur.3284 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Associations of maternal peripregnancy cannabis use with behavioral and developmental outcomes in children with and without symptoms of autism spectrum disorder: Study to Explore Early Development : Autism Research [texte imprimé] / Carolyn G. DIGUISEPPI, Auteur ; Tessa CRUME, Auteur ; Brady HOLST, Auteur ; Kaylynn AIONA, Auteur ; Julia VAN DYKE, Auteur ; Lisa A. CROEN, Auteur ; Julie L. DANIELS, Auteur ; Sandra FRIEDMAN, Auteur ; Katherine R. SABOURIN, Auteur ; Laura A. SCHIEVE, Auteur ; Lisa WIGGINS, Auteur ; Gayle C. WINDHAM, Auteur ; Cordelia ROBINSON ROSENBERG, Auteur . - p.202-216. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.202-216 Mots-clés : autism spectrum disorder  cannabis  child behavior  child preschool  developmental disabilities  pregnancy  prenatal risk factors  sleep wake disorders Index. décimale : PER Périodiques Résumé : Abstract Some studies report increased prevalence of autism spectrum disorder (ASD) and associated symptoms with prenatal cannabis exposure. We examined whether associations of maternal cannabis use from 3 months preconception through delivery (?peripregnancy?) with behavior and development in the offspring varied with the presence of ASD symptoms. Children ages 30 68 months with ASD symptoms (i.e., met study criteria for ASD or had ASD symptoms on standardized assessments or community ASD diagnosis, N 2734) and without ASD symptoms (other developmental delay/disorders or general population sample, N 3454) were evaluated with the Child Behavior Checklist and Mullen Scales of Early Learning. We examined cannabis use during three time periods: peripregnancy, pregnancy, and only preconception. Peripregnancy cannabis exposure was reported for 6.0% of children with and 4.6% of children without ASD symptoms. Preconception-only cannabis use (versus no use) was associated with more aggressive behavior, emotional reactivity, and sleep problems in children with ASD symptoms, but not in children without ASD symptoms. Cannabis use during pregnancy was associated with increased attention and sleep problems in children with ASD symptoms; these associations did not differ significantly by ASD symptoms. Peripregnancy cannabis use was not associated with child developmental abilities regardless of ASD symptoms. In summary, associations of peripregnancy cannabis use with some behavioral outcomes differed in children with and without ASD symptoms. With rising cannabis use among pregnant women, future studies that examine a range of developmental risks associated with timing and patterns of cannabis use prior to conception as well as during pregnancy could inform clinical guidance. En ligne : https://doi.org/10.1002/aur.3284 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Proximity of Maternal Time of Immigration to Child's Birth Is Associated With Autism Spectrum Disorder With Early Learning Delay Among Immigrant Populations in the United States: Findings From the Study to Explore Early Development / Kaylynn AIONA in Autism Research, 18-12 (December 2025)  

Public ISBD [article]  inAutism Research > 18-12 (December 2025) . - p.2419-2430 Titre : Proximity of Maternal Time of Immigration to Child's Birth Is Associated With Autism Spectrum Disorder With Early Learning Delay Among Immigrant Populations in the United States: Findings From the Study to Explore Early Development Type de document : texte imprimé Auteurs : Kaylynn AIONA, Auteur ; Tessa CRUME, Auteur ; Nuri REYES, Auteur ; Sarah J. SCHMIEGE, Auteur ; Janine YOUNG, Auteur ; Brady HOLST, Auteur ; Maureen S. DURKIN, Auteur ; Melissa MAGALLANES, Auteur ; Carolyn DIGUISEPPI, Auteur Article en page(s) : p.2419-2430 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  early learning delay  health disparities  immigrant  intellectual disability  migrant Index. décimale : PER Périodiques Résumé : ABSTRACT Our objective was to examine the relationship between the timing of parental US immigration and autism spectrum disorder (ASD) without early learning delay (ELD), ASD with ELD, and ELD alone among US-born children. We analyzed data from a multi-site case?control study that recruited children aged 2?5?years with ASD or non-ASD developmental disorders and same-age population controls. Parental demographics were collected from caregivers at study enrollment. Mullen Scales of Early Learning ≤?70 was used to define ELD. Among children with a non-US-born parent (N?=?1048), we used multinomial logistic regression to examine time from parental immigration to the child's birth in relation to ASD alone, ASD with ELD (ASD?+?ELD), and ELD alone compared to population controls. Having a non-US-born mother (regardless of the father's birthplace) versus a non-US-born father only was evaluated as a potential effect modifier. Among those with a non-US-born mother, closer proximity of maternal time of immigration to the child's birth is associated with increased odds for ASD?+?ELD and ELD alone. There was no significant association between years since US arrival and ASD alone. Among those with a non-US-born father only, we did not observe a significant relationship between time since paternal US arrival and ASD/ELD categories. Our study suggests that time-varying exposures among immigrant mothers may be of importance for the development of ASD?+?ELD and ELD alone in the offspring. These results may inform research into the etiology of ASD and ELD and ways to support immigrant women of childbearing age. En ligne : https://doi.org/10.1002/aur.70133 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=578 [article] Proximity of Maternal Time of Immigration to Child's Birth Is Associated With Autism Spectrum Disorder With Early Learning Delay Among Immigrant Populations in the United States: Findings From the Study to Explore Early Development [texte imprimé] / Kaylynn AIONA, Auteur ; Tessa CRUME, Auteur ; Nuri REYES, Auteur ; Sarah J. SCHMIEGE, Auteur ; Janine YOUNG, Auteur ; Brady HOLST, Auteur ; Maureen S. DURKIN, Auteur ; Melissa MAGALLANES, Auteur ; Carolyn DIGUISEPPI, Auteur . - p.2419-2430. Langues : Anglais (eng) in Autism Research > 18-12 (December 2025) . - p.2419-2430 Mots-clés : autism spectrum disorder  early learning delay  health disparities  immigrant  intellectual disability  migrant Index. décimale : PER Périodiques Résumé : ABSTRACT Our objective was to examine the relationship between the timing of parental US immigration and autism spectrum disorder (ASD) without early learning delay (ELD), ASD with ELD, and ELD alone among US-born children. We analyzed data from a multi-site case?control study that recruited children aged 2?5?years with ASD or non-ASD developmental disorders and same-age population controls. Parental demographics were collected from caregivers at study enrollment. Mullen Scales of Early Learning ≤?70 was used to define ELD. Among children with a non-US-born parent (N?=?1048), we used multinomial logistic regression to examine time from parental immigration to the child's birth in relation to ASD alone, ASD with ELD (ASD?+?ELD), and ELD alone compared to population controls. Having a non-US-born mother (regardless of the father's birthplace) versus a non-US-born father only was evaluated as a potential effect modifier. Among those with a non-US-born mother, closer proximity of maternal time of immigration to the child's birth is associated with increased odds for ASD?+?ELD and ELD alone. There was no significant association between years since US arrival and ASD alone. Among those with a non-US-born father only, we did not observe a significant relationship between time since paternal US arrival and ASD/ELD categories. Our study suggests that time-varying exposures among immigrant mothers may be of importance for the development of ASD?+?ELD and ELD alone in the offspring. These results may inform research into the etiology of ASD and ELD and ways to support immigrant women of childbearing age. En ligne : https://doi.org/10.1002/aur.70133 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=578

Real-world imitation in preschool age children with autism spectrum disorder: Findings from the Study to Explore Early Development (SEED) / Eric J. MOODY in Research in Autism, 129 (January 2026)  

Public ISBD [article]  inResearch in Autism > 129 (January 2026) . - 202737 Titre : Real-world imitation in preschool age children with autism spectrum disorder: Findings from the Study to Explore Early Development (SEED) Type de document : texte imprimé Auteurs : Eric J. MOODY, Auteur ; Haley A. STURGES, Auteur ; Brian BARGER, Auteur ; Brady HOLST, Auteur ; Ethan DAHL, Auteur ; Steven A. ROSENBERG, Auteur Année de publication : 2026 Article en page(s) : 202737 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Imitation preschool-aged  Internalizing problems  Developmental level  Demographic factors Index. décimale : PER Périodiques Résumé : There are several well-known associations between imitation deficits and autism spectrum disorder (ASD). However, it remains unclear what mechanisms underly these deficits, and there is little evidence from more ecologically valid sources. To explore child characteristics and demographic factors that may relate to imitation, the present study analyzed data from a subset of children with ASD that participated in the Study to Explore Early Development (SEED; N = 2059, 81 % male). SEED is a large case-control study of the risk factors of ASD. We used items that capture parent report of real-world imitation ability and used a hierarchical regression to explore associations with ASD symptoms, age, developmental level, internalizing and externalizing problems, and demographic factors. We found that as restricted and repetitive behaviors increased, imitation decreased, and that some of the variance in this association was accounted for by other child and demographic factors. However, imitation was not related to social problems related to ASD. Internalizing problems were also negatively associated with imitation, whereas chronological age and developmental level were positively associated with imitation. Black children also showed higher levels of imitation relative to White children. These data suggest that imitation is a complex phenomenon, and that both autistic behaviors, as well as other non-autistic child characteristics (age, developmental level, internalizing problems, race) may account for some portion of the relationship between imitation and ASD. This serves as a starting point for future research to investigate the nuanced relationship between imitation and ASD. En ligne : https://doi.org/10.1016/j.reia.2025.202737 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=573 [article] Real-world imitation in preschool age children with autism spectrum disorder: Findings from the Study to Explore Early Development (SEED) [texte imprimé] / Eric J. MOODY, Auteur ; Haley A. STURGES, Auteur ; Brian BARGER, Auteur ; Brady HOLST, Auteur ; Ethan DAHL, Auteur ; Steven A. ROSENBERG, Auteur . - 2026 . - 202737. Langues : Anglais (eng) in Research in Autism > 129 (January 2026) . - 202737 Mots-clés : Autism spectrum disorder  Imitation preschool-aged  Internalizing problems  Developmental level  Demographic factors Index. décimale : PER Périodiques Résumé : There are several well-known associations between imitation deficits and autism spectrum disorder (ASD). However, it remains unclear what mechanisms underly these deficits, and there is little evidence from more ecologically valid sources. To explore child characteristics and demographic factors that may relate to imitation, the present study analyzed data from a subset of children with ASD that participated in the Study to Explore Early Development (SEED; N = 2059, 81 % male). SEED is a large case-control study of the risk factors of ASD. We used items that capture parent report of real-world imitation ability and used a hierarchical regression to explore associations with ASD symptoms, age, developmental level, internalizing and externalizing problems, and demographic factors. We found that as restricted and repetitive behaviors increased, imitation decreased, and that some of the variance in this association was accounted for by other child and demographic factors. However, imitation was not related to social problems related to ASD. Internalizing problems were also negatively associated with imitation, whereas chronological age and developmental level were positively associated with imitation. Black children also showed higher levels of imitation relative to White children. These data suggest that imitation is a complex phenomenon, and that both autistic behaviors, as well as other non-autistic child characteristics (age, developmental level, internalizing problems, race) may account for some portion of the relationship between imitation and ASD. This serves as a starting point for future research to investigate the nuanced relationship between imitation and ASD. En ligne : https://doi.org/10.1016/j.reia.2025.202737 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=573

Resilience to COVID-19-related challenges in preschool-aged children with and without autism spectrum disorder / Eric J. MOODY in Research in Autism, 128 (October 2025)  

Public ISBD [article]  inResearch in Autism > 128 (October 2025) . - p.202705 Titre : Resilience to COVID-19-related challenges in preschool-aged children with and without autism spectrum disorder Type de document : texte imprimé Auteurs : Eric J. MOODY, Auteur ; Brady HOLST, Auteur ; Haley A. STURGES, Auteur ; Ethan DAHL, Auteur ; Tessa CRUME, Auteur ; Jamie KACZANIUK, Auteur ; Maureen S. DURKIN, Auteur ; Kristina HIGHTSHOE, Auteur ; Cy NADLER, Auteur ; Karen PAZOL, Auteur ; Steven A. ROSENBERG, Auteur ; Lisa WIGGINS, Auteur ; Carolyn G. DIGUISEPPI, Auteur Article en page(s) : p.202705 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  child resilience  maternal mental health  COVID-19 impact Index. décimale : PER Périodiques Résumé : This study examined factors related to resilience in children (46–91 months) with and without autism spectrum disorder (ASD) during the COVID-19 pandemic. From January 2021 to June 2021 a cross-sectional questionnaire measuring the pandemic’s impact on participants was administered to participants from The Study to Explore Early Development (SEED; N = 641). A sum score of items measuring child resilience was computed as an outcome. A Tobit regression was used to model the impact of child’s ASD status, demographic variables, child developmental characteristics, family income, parent work characteristics, and other family and maternal characteristics. There was no association between resilience and ASD status, but it was inversely related to maternal mental health challenges. Resilience was also significantly lower for Asian than non-Hispanic White children and inversely associated with child behavior problems. There was an interaction between loss of work and the family income. Child resilience is a complex phenomenon impacted by child, family, and social factors. Further research is needed to understand how to address factors negatively associated with child resilience and promote factors positively associated with child resilience. Focusing on family and social factors, along with direct child support, may promote resilience in all children. En ligne : https://doi.org/10.1016/j.reia.2025.202705 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=570 [article] Resilience to COVID-19-related challenges in preschool-aged children with and without autism spectrum disorder [texte imprimé] / Eric J. MOODY, Auteur ; Brady HOLST, Auteur ; Haley A. STURGES, Auteur ; Ethan DAHL, Auteur ; Tessa CRUME, Auteur ; Jamie KACZANIUK, Auteur ; Maureen S. DURKIN, Auteur ; Kristina HIGHTSHOE, Auteur ; Cy NADLER, Auteur ; Karen PAZOL, Auteur ; Steven A. ROSENBERG, Auteur ; Lisa WIGGINS, Auteur ; Carolyn G. DIGUISEPPI, Auteur . - p.202705. Langues : Anglais (eng) in Research in Autism > 128 (October 2025) . - p.202705 Mots-clés : Autism spectrum disorder  child resilience  maternal mental health  COVID-19 impact Index. décimale : PER Périodiques Résumé : This study examined factors related to resilience in children (46–91 months) with and without autism spectrum disorder (ASD) during the COVID-19 pandemic. From January 2021 to June 2021 a cross-sectional questionnaire measuring the pandemic’s impact on participants was administered to participants from The Study to Explore Early Development (SEED; N = 641). A sum score of items measuring child resilience was computed as an outcome. A Tobit regression was used to model the impact of child’s ASD status, demographic variables, child developmental characteristics, family income, parent work characteristics, and other family and maternal characteristics. There was no association between resilience and ASD status, but it was inversely related to maternal mental health challenges. Resilience was also significantly lower for Asian than non-Hispanic White children and inversely associated with child behavior problems. There was an interaction between loss of work and the family income. Child resilience is a complex phenomenon impacted by child, family, and social factors. Further research is needed to understand how to address factors negatively associated with child resilience and promote factors positively associated with child resilience. Focusing on family and social factors, along with direct child support, may promote resilience in all children. En ligne : https://doi.org/10.1016/j.reia.2025.202705 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=570

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