EEG frontal alpha asymmetry mediates the association between maternal and child internalizing symptoms in childhood / Dashiell SACKS in Journal of Child Psychology and Psychiatry, 66-8 (August 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-8 (August 2025) . - p.1129-1140 Titre : EEG frontal alpha asymmetry mediates the association between maternal and child internalizing symptoms in childhood Type de document : texte imprimé Auteurs : Dashiell SACKS, Auteur ; Yiyi WANG, Auteur ; Asja ABRON, Auteur ; Kaitlin M. MULLIGAN, Auteur ; Caroline M. KELSEY, Auteur ; Wanze XIE, Auteur ; Charles A. NELSON, Auteur ; Michelle BOSQUET ENLOW, Auteur Article en page(s) : p.1129-1140 Langues : Anglais (eng) Mots-clés : Maternal depression  maternal anxiety  frontal alpha asymmetry  internalizing symptoms  EEG Index. décimale : PER Périodiques Résumé : Background Anxiety and depression are highly prevalent in youth and can cause significant distress and functional impairment. The presence of maternal anxiety and depression are well-established risk factors for child internalizing psychopathology, yet the responsible mechanisms linking the two remain unclear. Methods We examined the potential mediating and moderating roles of EEG frontal alpha asymmetry (FAA) in the intergenerational transmission of internalizing symptoms in a longitudinal sample of N 323 mother?child dyads. Self-report maternal internalizing symptoms were evaluated at child age 3 years and 5 years, child EEG at 5 years, and parent-report child internalizing symptoms at age 7 years. Mediation was evaluated via bootstrapped (N 5,000) confidence intervals. Results We found significant associations among maternal internalizing (anxiety, depressive) symptoms when their children were ages 3 and 5 years, child FAA at age 5 years, and child internalizing symptoms at age 7 years. There was a significant mediation effect, whereby greater maternal anxiety and depressive symptoms at age 3 years were significantly associated with FAA (greater relative right cortical activation) in children at age 5 years, which, in turn, was significantly associated with greater child internalizing symptoms at age 7 years (ps < .001). There was no moderating effect of FAA on the association between maternal internalizing symptoms at age 5 years and child internalizing symptoms at age 7 years. Conclusions Greater right frontal asymmetry may be a neurophysiological mechanism that mediates the intergenerational transmission of internalizing symptoms. En ligne : https://doi.org/10.1111/jcpp.14129 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=565 [article] EEG frontal alpha asymmetry mediates the association between maternal and child internalizing symptoms in childhood [texte imprimé] / Dashiell SACKS, Auteur ; Yiyi WANG, Auteur ; Asja ABRON, Auteur ; Kaitlin M. MULLIGAN, Auteur ; Caroline M. KELSEY, Auteur ; Wanze XIE, Auteur ; Charles A. NELSON, Auteur ; Michelle BOSQUET ENLOW, Auteur . - p.1129-1140. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-8 (August 2025) . - p.1129-1140 Mots-clés : Maternal depression  maternal anxiety  frontal alpha asymmetry  internalizing symptoms  EEG Index. décimale : PER Périodiques Résumé : Background Anxiety and depression are highly prevalent in youth and can cause significant distress and functional impairment. The presence of maternal anxiety and depression are well-established risk factors for child internalizing psychopathology, yet the responsible mechanisms linking the two remain unclear. Methods We examined the potential mediating and moderating roles of EEG frontal alpha asymmetry (FAA) in the intergenerational transmission of internalizing symptoms in a longitudinal sample of N 323 mother?child dyads. Self-report maternal internalizing symptoms were evaluated at child age 3 years and 5 years, child EEG at 5 years, and parent-report child internalizing symptoms at age 7 years. Mediation was evaluated via bootstrapped (N 5,000) confidence intervals. Results We found significant associations among maternal internalizing (anxiety, depressive) symptoms when their children were ages 3 and 5 years, child FAA at age 5 years, and child internalizing symptoms at age 7 years. There was a significant mediation effect, whereby greater maternal anxiety and depressive symptoms at age 3 years were significantly associated with FAA (greater relative right cortical activation) in children at age 5 years, which, in turn, was significantly associated with greater child internalizing symptoms at age 7 years (ps < .001). There was no moderating effect of FAA on the association between maternal internalizing symptoms at age 5 years and child internalizing symptoms at age 7 years. Conclusions Greater right frontal asymmetry may be a neurophysiological mechanism that mediates the intergenerational transmission of internalizing symptoms. En ligne : https://doi.org/10.1111/jcpp.14129 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=565

The association between temperament and polygenic score for psychopathology from infancy to middle childhood / Eloise FREITAG in Journal of Child Psychology and Psychiatry, 66-8 (August 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-8 (August 2025) . - p.1155-1169 Titre : The association between temperament and polygenic score for psychopathology from infancy to middle childhood Type de document : texte imprimé Auteurs : Eloise FREITAG, Auteur ; Caroline M. KELSEY, Auteur ; Euclides José DE MENDONÇA FILHO, Auteur ; Irina POKHVISNEVA, Auteur ; Sachin PATEL, Auteur ; Patricia Pelufo SILVEIRA, Auteur ; Michelle BOSQUET ENLOW, Auteur ; Charles A. NELSON, Auteur Article en page(s) : p.1155-1169 Langues : Anglais (eng) Mots-clés : ADHD  anxiety  childhood  infancy  polygenic scores  temperament Index. décimale : PER Périodiques Résumé : Background Certain temperament characteristics, such as low effortful control and high negative affectivity, are linked to an elevated likelihood for later psychopathology. Although genetic vulnerability has been associated with a number of psychiatric conditions, little work has examined the genetic architecture underlying temperament or the genetic overlap between early temperament profiles and later mental health outcomes. The present study examined associations of polygenic scores for anxiety (PGS-Anxiety) and ADHD (PGS-ADHD) with temperament characteristics in a longitudinal sample of children assessed from infancy through age 7 years. Methods Analyses were conducted in a sample of children (European Ancestry n 476; Full Sample [European and other ancestries] N 606). Results We observed an age-by-PGS interaction on effortful control. As children aged, there appeared to be stronger negative associations between PGS-ADHD and effortful control. No associations were observed between PGS-Anxiety and negative affectivity. Conclusions Overall, the findings suggest some support for associations between genetic underpinnings for externalizing psychopathology and temperament that increase over time. En ligne : https://doi.org/10.1111/jcpp.14140 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=565 [article] The association between temperament and polygenic score for psychopathology from infancy to middle childhood [texte imprimé] / Eloise FREITAG, Auteur ; Caroline M. KELSEY, Auteur ; Euclides José DE MENDONÇA FILHO, Auteur ; Irina POKHVISNEVA, Auteur ; Sachin PATEL, Auteur ; Patricia Pelufo SILVEIRA, Auteur ; Michelle BOSQUET ENLOW, Auteur ; Charles A. NELSON, Auteur . - p.1155-1169. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-8 (August 2025) . - p.1155-1169 Mots-clés : ADHD  anxiety  childhood  infancy  polygenic scores  temperament Index. décimale : PER Périodiques Résumé : Background Certain temperament characteristics, such as low effortful control and high negative affectivity, are linked to an elevated likelihood for later psychopathology. Although genetic vulnerability has been associated with a number of psychiatric conditions, little work has examined the genetic architecture underlying temperament or the genetic overlap between early temperament profiles and later mental health outcomes. The present study examined associations of polygenic scores for anxiety (PGS-Anxiety) and ADHD (PGS-ADHD) with temperament characteristics in a longitudinal sample of children assessed from infancy through age 7 years. Methods Analyses were conducted in a sample of children (European Ancestry n 476; Full Sample [European and other ancestries] N 606). Results We observed an age-by-PGS interaction on effortful control. As children aged, there appeared to be stronger negative associations between PGS-ADHD and effortful control. No associations were observed between PGS-Anxiety and negative affectivity. Conclusions Overall, the findings suggest some support for associations between genetic underpinnings for externalizing psychopathology and temperament that increase over time. En ligne : https://doi.org/10.1111/jcpp.14140 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=565

---

1 (1 - 2 / 2) Par page : 25 50 100 200