Alpha Asymmetry in Infants at Risk for Autism Spectrum Disorders / Laurel GABARD-DURNAM in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.473-480 Titre : Alpha Asymmetry in Infants at Risk for Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Laurel GABARD-DURNAM, Auteur ; Adrienne L. TIERNEY, Auteur ; Vanessa VOGEL-FARLEY, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur Article en page(s) : p.473-480 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Infant siblings  Electroencephalography  Frontal alpha asymmetry  Endophenotype Index. décimale : PER Périodiques Résumé : An emerging focus of research on autism spectrum disorder (ASD) targets the identification of early-developing ASD endophenotypes using infant siblings of affected children. One potential neural endophenotype is resting frontal electroencephalogram (EEG) alpha asymmetry, a metric of hemispheric organization. Here, we examined the development of frontal EEG alpha asymmetry in ASD high-risk and low-risk infant populations. Our findings demonstrate that low and high-risk infants show different patterns of alpha asymmetry at 6 months of age and opposite growth trajectories in asymmetry over the following 12 months. These results support the candidacy of alpha asymmetry as an early neural ASD endophenotype. En ligne : http://dx.doi.org/10.1007/s10803-013-1926-4 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2584 [article] Alpha Asymmetry in Infants at Risk for Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Laurel GABARD-DURNAM, Auteur ; Adrienne L. TIERNEY, Auteur ; Vanessa VOGEL-FARLEY, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur . - p.473-480. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-2 (February 2015) . - p.473-480 Mots-clés : Autism spectrum disorder  Infant siblings  Electroencephalography  Frontal alpha asymmetry  Endophenotype Index. décimale : PER Périodiques Résumé : An emerging focus of research on autism spectrum disorder (ASD) targets the identification of early-developing ASD endophenotypes using infant siblings of affected children. One potential neural endophenotype is resting frontal electroencephalogram (EEG) alpha asymmetry, a metric of hemispheric organization. Here, we examined the development of frontal EEG alpha asymmetry in ASD high-risk and low-risk infant populations. Our findings demonstrate that low and high-risk infants show different patterns of alpha asymmetry at 6 months of age and opposite growth trajectories in asymmetry over the following 12 months. These results support the candidacy of alpha asymmetry as an early neural ASD endophenotype. En ligne : http://dx.doi.org/10.1007/s10803-013-1926-4 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2584

Attention Allocation During Exploration of Visual Arrays in ASD: Results from the ABC-CT Feasibility Study / Tawny TSANG in Journal of Autism and Developmental Disorders, 53-8 (August 2023)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 53-8 (August 2023) . - p.3220-3229 Titre : Attention Allocation During Exploration of Visual Arrays in ASD: Results from the ABC-CT Feasibility Study Type de document : Texte imprimé et/ou numérique Auteurs : Tawny TSANG, Auteur ; Adam J. NAPLES, Auteur ; Erin C. BARNEY, Auteur ; Minhang XIE, Auteur ; Raphael BERNIER, Auteur ; Geraldine DAWSON, Auteur ; James DZIURA, Auteur ; Susan FAJA, Auteur ; Shafali Spurling JESTE, Auteur ; James C. MCPARTLAND, Auteur ; Charles A. NELSON, Auteur ; Michael MURIAS, Auteur ; Helen SEOW, Auteur ; Catherine SUGAR, Auteur ; Sara J. WEBB, Auteur ; Frederick SHIC, Auteur ; Scott P. JOHNSON, Auteur Article en page(s) : p.3220-3229 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Visual exploration paradigms involving object arrays have been used to examine salience of social stimuli such as faces in ASD. Recent work suggests performance on these paradigms may associate with clinical features of ASD. We evaluate metrics from a visual exploration paradigm in 4-to-11-year-old children with ASD (n?=?23; 18 males) and typical development (TD; n?=?23; 13 males). Presented with arrays containing faces and nonsocial stimuli, children with ASD looked less at (p?=?0.002) and showed fewer fixations to (p?=?0.022) faces than TD children, and spent less time looking at each object on average (p?=?0.004). Attention to the screen and faces correlated positively with social and cognitive skills in the ASD group (ps? En ligne : https://doi.org/10.1007/s10803-022-05569-0 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=5084 [article] Attention Allocation During Exploration of Visual Arrays in ASD: Results from the ABC-CT Feasibility Study [Texte imprimé et/ou numérique] / Tawny TSANG, Auteur ; Adam J. NAPLES, Auteur ; Erin C. BARNEY, Auteur ; Minhang XIE, Auteur ; Raphael BERNIER, Auteur ; Geraldine DAWSON, Auteur ; James DZIURA, Auteur ; Susan FAJA, Auteur ; Shafali Spurling JESTE, Auteur ; James C. MCPARTLAND, Auteur ; Charles A. NELSON, Auteur ; Michael MURIAS, Auteur ; Helen SEOW, Auteur ; Catherine SUGAR, Auteur ; Sara J. WEBB, Auteur ; Frederick SHIC, Auteur ; Scott P. JOHNSON, Auteur . - p.3220-3229. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 53-8 (August 2023) . - p.3220-3229 Index. décimale : PER Périodiques Résumé : Visual exploration paradigms involving object arrays have been used to examine salience of social stimuli such as faces in ASD. Recent work suggests performance on these paradigms may associate with clinical features of ASD. We evaluate metrics from a visual exploration paradigm in 4-to-11-year-old children with ASD (n?=?23; 18 males) and typical development (TD; n?=?23; 13 males). Presented with arrays containing faces and nonsocial stimuli, children with ASD looked less at (p?=?0.002) and showed fewer fixations to (p?=?0.022) faces than TD children, and spent less time looking at each object on average (p?=?0.004). Attention to the screen and faces correlated positively with social and cognitive skills in the ASD group (ps? En ligne : https://doi.org/10.1007/s10803-022-05569-0 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=5084

Atypical Hemispheric Specialization for Faces in Infants at Risk for Autism Spectrum Disorder / Brandon KEEHN in Autism Research, 8-2 (April 2015)  

Public ISBD [article]  inAutism Research > 8-2 (April 2015) . - p.187-198 Titre : Atypical Hemispheric Specialization for Faces in Infants at Risk for Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Brandon KEEHN, Auteur ; Vanessa VOGEL-FARLEY, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur Article en page(s) : p.187-198 Langues : Anglais (eng) Mots-clés : autism  EEG coherence  face processing  hemispheric specialization  endophenotype  gamma  infancy Index. décimale : PER Périodiques Résumé : Among the many experimental findings that tend to distinguish those with and without autism spectrum disorder (ASD) are face processing deficits, reduced hemispheric specialization, and atypical neurostructural and functional connectivity. To investigate the earliest manifestations of these features, we examined lateralization of event-related gamma-band coherence to faces during the first year of life in infants at high risk for autism (HRA; defined as having an older sibling with ASD) who were compared with low-risk comparison (LRC) infants, defined as having no family history of ASD. Participants included 49 HRA and 46 LRC infants who contributed a total of 127 data sets at 6 and 12 months. Electroencephalography was recorded while infants viewed images of familiar/unfamiliar faces. Event-related gamma-band (30–50?Hz) phase coherence between anterior–posterior electrode pairs for left and right hemispheres was computed. Developmental trajectories for lateralization of intra-hemispheric coherence were significantly different in HRA and LRC infants: by 12 months, HRA infants showed significantly greater leftward lateralization compared with LRC infants who showed rightward lateralization. Preliminary results indicate that infants who later met criteria for ASD were those that showed the greatest leftward lateralization. HRA infants demonstrate an aberrant pattern of leftward lateralization of intra-hemispheric coherence by the end of the first year of life, suggesting that the network specialized for face processing may develop atypically. Further, infants with the greatest leftward asymmetry at 12 months where those that later met criteria for ASD, providing support to the growing body of evidence that atypical hemispheric specialization may be an early neurobiological marker for ASD. En ligne : http://dx.doi.org/10.1002/aur.1438 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2568 [article] Atypical Hemispheric Specialization for Faces in Infants at Risk for Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Brandon KEEHN, Auteur ; Vanessa VOGEL-FARLEY, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur . - p.187-198. Langues : Anglais (eng) in Autism Research > 8-2 (April 2015) . - p.187-198 Mots-clés : autism  EEG coherence  face processing  hemispheric specialization  endophenotype  gamma  infancy Index. décimale : PER Périodiques Résumé : Among the many experimental findings that tend to distinguish those with and without autism spectrum disorder (ASD) are face processing deficits, reduced hemispheric specialization, and atypical neurostructural and functional connectivity. To investigate the earliest manifestations of these features, we examined lateralization of event-related gamma-band coherence to faces during the first year of life in infants at high risk for autism (HRA; defined as having an older sibling with ASD) who were compared with low-risk comparison (LRC) infants, defined as having no family history of ASD. Participants included 49 HRA and 46 LRC infants who contributed a total of 127 data sets at 6 and 12 months. Electroencephalography was recorded while infants viewed images of familiar/unfamiliar faces. Event-related gamma-band (30–50?Hz) phase coherence between anterior–posterior electrode pairs for left and right hemispheres was computed. Developmental trajectories for lateralization of intra-hemispheric coherence were significantly different in HRA and LRC infants: by 12 months, HRA infants showed significantly greater leftward lateralization compared with LRC infants who showed rightward lateralization. Preliminary results indicate that infants who later met criteria for ASD were those that showed the greatest leftward lateralization. HRA infants demonstrate an aberrant pattern of leftward lateralization of intra-hemispheric coherence by the end of the first year of life, suggesting that the network specialized for face processing may develop atypically. Further, infants with the greatest leftward asymmetry at 12 months where those that later met criteria for ASD, providing support to the growing body of evidence that atypical hemispheric specialization may be an early neurobiological marker for ASD. En ligne : http://dx.doi.org/10.1002/aur.1438 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2568

Commentary: Becoming social – a commentary on Happé Frith (2014) / Charles A. NELSON in Journal of Child Psychology and Psychiatry, 55-6 (June 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-6 (June 2014) . - p.578-581 Titre : Commentary: Becoming social – a commentary on Happé Frith (2014) Type de document : Texte imprimé et/ou numérique Auteurs : Charles A. NELSON, Auteur Année de publication : 2014 Article en page(s) : p.578-581 Langues : Anglais (eng) Mots-clés : Developmental neuroscience  social cognition  social development  autism Index. décimale : PER Périodiques Résumé : The field of developmental cognitive neuroscience is now established as a discipline at the nexus of the broader fields of developmental psychology and cognitive neuroscience. Sitting in its rear view mirror, but gaining rapidly, is the nascent discipline of developmental social neuroscience. Given the relative youth of this field, it is not surprising that a great deal of energy has gone into generating a rich corpus of empirical data. En ligne : http://dx.doi.org/10.1111/jcpp.12254 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2340 [article] Commentary: Becoming social – a commentary on Happé Frith (2014) [Texte imprimé et/ou numérique] / Charles A. NELSON, Auteur . - 2014 . - p.578-581. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-6 (June 2014) . - p.578-581 Mots-clés : Developmental neuroscience  social cognition  social development  autism Index. décimale : PER Périodiques Résumé : The field of developmental cognitive neuroscience is now established as a discipline at the nexus of the broader fields of developmental psychology and cognitive neuroscience. Sitting in its rear view mirror, but gaining rapidly, is the nascent discipline of developmental social neuroscience. Given the relative youth of this field, it is not surprising that a great deal of energy has gone into generating a rich corpus of empirical data. En ligne : http://dx.doi.org/10.1111/jcpp.12254 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2340

Commentary: Developmental origins of autism and ADHD – a commentary on Johnson et al. () / Charles A. NELSON in Journal of Child Psychology and Psychiatry, 56-3 (March 2015)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 56-3 (March 2015) . - p.248-250 Titre : Commentary: Developmental origins of autism and ADHD – a commentary on Johnson et al. () Type de document : Texte imprimé et/ou numérique Auteurs : Charles A. NELSON, Auteur Article en page(s) : p.248-250 Langues : Anglais (eng) Mots-clés : Autism  ADHD  neurodevelopmental origins  early experience  neural and molecular mechanisms Index. décimale : PER Périodiques Résumé : Autism (autistic spectrum disorder, ASD) and attention deficit hyperactivity disorder (ADHD) are two highly prevalent neurodevelopmental disorders. Current estimates for autism exceed 1% For ADHD, the 2013 US-based life time prevalence figure is 11%. Both disorders are also highly heritable. Intriguingly, approximately 50% of children with ASD also meet criteria for ADHD. Between their high heritability and comorbidity, some have wondered whether these two seemingly different disorders might in fact be related at some deep neurobiological level. The notion that these two disorders may be related is surprising when one considers the fact that autism generally appears in the first 1–2 years of life, whereas it is virtually impossible to identify ADHD during this time frame; indeed, inattentiveness and hyperactivity tend to be traits that are shared by nearly all toddlers, making a stable diagnosis of ADHD virtually impossible until early childhood (although a reliable diagnosis can generally be made during the preschool period). Like many neurodevelopmental disorders, early identification and early treatment are essential to easing the life time burden of these disorders. Of course, early treatment is predicated on early identification and it is for this reason that the review article by Johnson and colleagues is so intriguing, as it sets out to determine whether these disorders can be identified in the infancy period. It also raises a number of puzzling issues that remain undiscussed. En ligne : http://dx.doi.org/10.1111/jcpp.12375 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2599 [article] Commentary: Developmental origins of autism and ADHD – a commentary on Johnson et al. () [Texte imprimé et/ou numérique] / Charles A. NELSON, Auteur . - p.248-250. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 56-3 (March 2015) . - p.248-250 Mots-clés : Autism  ADHD  neurodevelopmental origins  early experience  neural and molecular mechanisms Index. décimale : PER Périodiques Résumé : Autism (autistic spectrum disorder, ASD) and attention deficit hyperactivity disorder (ADHD) are two highly prevalent neurodevelopmental disorders. Current estimates for autism exceed 1% For ADHD, the 2013 US-based life time prevalence figure is 11%. Both disorders are also highly heritable. Intriguingly, approximately 50% of children with ASD also meet criteria for ADHD. Between their high heritability and comorbidity, some have wondered whether these two seemingly different disorders might in fact be related at some deep neurobiological level. The notion that these two disorders may be related is surprising when one considers the fact that autism generally appears in the first 1–2 years of life, whereas it is virtually impossible to identify ADHD during this time frame; indeed, inattentiveness and hyperactivity tend to be traits that are shared by nearly all toddlers, making a stable diagnosis of ADHD virtually impossible until early childhood (although a reliable diagnosis can generally be made during the preschool period). Like many neurodevelopmental disorders, early identification and early treatment are essential to easing the life time burden of these disorders. Of course, early treatment is predicated on early identification and it is for this reason that the review article by Johnson and colleagues is so intriguing, as it sets out to determine whether these disorders can be identified in the infancy period. It also raises a number of puzzling issues that remain undiscussed. En ligne : http://dx.doi.org/10.1111/jcpp.12375 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2599

Deficits in error monitoring are associated with externalizing but not internalizing behaviors among children with a history of institutionalization / Sonya TROLLER-RENFREE in Journal of Child Psychology and Psychiatry, 57-10 (October 2016)  

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Diary Reports of Concerns in Mothers of Infant Siblings of Children with Autism Across the First Year of Life / Meagan R. TALBOTT in Journal of Autism and Developmental Disorders, 45-7 (July 2015)  

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Differences in Neural Correlates of Speech Perception in 3 Month Olds at High and Low Risk for Autism Spectrum Disorder / Laura A. EDWARDS in Journal of Autism and Developmental Disorders, 47-10 (October 2017)  

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Differing Developmental Trajectories in Heart Rate Responses to Speech Stimuli in Infants at High and Low Risk for Autism Spectrum Disorder / Katherine L. PERDUE in Journal of Autism and Developmental Disorders, 47-8 (August 2017)  

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Early autism symptoms in infants with tuberous sclerosis complex / Nicole M. MCDONALD in Autism Research, 10-12 (December 2017)  

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Early sex differences are not autism-specific: A Baby Siblings Research Consortium (BSRC) study / Daniel S. MESSINGER in Molecular Autism, (June 2015)  

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Effects of early institutionalization on emotion processing in 12-year-old youth / Johanna BICK in Development and Psychopathology, 29-5 (December 2017)  

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Eye-Tracking Measurements of Language Processing: Developmental Differences in Children at High Risk for ASD / Meia CHITA-TEGMARK in Journal of Autism and Developmental Disorders, 45-10 (October 2015)  

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Guidelines and Best Practices for Electrophysiological Data Collection, Analysis and Reporting in Autism / Sara Jane WEBB in Journal of Autism and Developmental Disorders, 45-2 (February 2015)  

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Language Differences at 12 Months in Infants Who Develop Autism Spectrum Disorder / DeWayne C. LAZENBY in Journal of Autism and Developmental Disorders, 46-3 (March 2016)  

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