Atypical Resting-State EEG Graph Metrics of Network Efficiency Across Development in Autism and Their Association with Social Cognition: Results from the LEAP Study / E. DE JONGE in Journal of Autism and Developmental Disorders, 56-7 (July 2026)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 56-7 (July 2026) . - p.2557-2573 Titre : Atypical Resting-State EEG Graph Metrics of Network Efficiency Across Development in Autism and Their Association with Social Cognition: Results from the LEAP Study Type de document : texte imprimé Auteurs : E. DE JONGE, Auteur ; P. GARCÉS, Auteur ; A. DE BILDT, Auteur ; Y. GROEN, Auteur ; E.J.H. JONES, Auteur ; L. MASON, Auteur ; R. J. HOLT, Auteur ; H. HAYWARD, Auteur ; D. MURPHY, Auteur ; B. OAKLEY, Auteur ; T. CHARMAN, Auteur ; J. AHMAD, Auteur ; S. BARON-COHEN, Auteur ; M.H. JOHNSON, Auteur ; T. BANASCHEWSKI, Auteur ; S. DURSTON, Auteur ; B. ORANJE, Auteur ; S. BÖLTE, Auteur ; J. BUITELAAR, Auteur ; P. J. HOEKSTRA, Auteur ; A. DIETRICH, Auteur ; E. U. Aims Leap group THE, Auteur Article en page(s) : p.2557-2573 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism has been associated with differences in functional brain network organization. However, the exact nature of these differences across development compared to non-autistic individuals and their relationship to autism-related social cognition, remains unclear. This study first aimed to identify EEG resting-state network characteristics in autistic versus non-autistic children, adolescents, and adults. Second, we investigated associations with social cognition measures. Analyzing resting-state EEG data from the EU-AIMS Longitudinal European Autism Project, we compared network metrics (global efficiency, clustering coefficient, and small-worldness) between 344 autistic and non-autistic individuals within and across age groups in four frequency bands (delta, theta, alpha, and beta). If significant, we explored their relationships to measures of empathy (empathy quotient), complex emotion recognition [reading the mind in the eyes task (RMET)], and theory of mind (animated shapes task). Compared to their non-autistic peers, autistic adolescents showed lower alpha global efficiency, while autistic adults showed lower alpha clustering and small-worldness. No network differences were observed among children. In adolescents, higher long-range integration was tentatively associated with higher RMET scores; in those with high autistic traits, higher long-range integration related to fewer parent-reported empathic behaviors. No brain-behavior relationships were observed in adults. Our findings suggest subtle differences in network topology between autistic and non-autistic individuals, with less efficient long-range efficiency during adolescence, and less local and overall network efficiency in adulthood. Furthermore, long-range integration may play a role in complex emotion recognition and empathy difficulties associated with autism in adolescence. En ligne : https://doi.org/10.1007/s10803-025-06731-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=590 [article] Atypical Resting-State EEG Graph Metrics of Network Efficiency Across Development in Autism and Their Association with Social Cognition: Results from the LEAP Study [texte imprimé] / E. DE JONGE, Auteur ; P. GARCÉS, Auteur ; A. DE BILDT, Auteur ; Y. GROEN, Auteur ; E.J.H. JONES, Auteur ; L. MASON, Auteur ; R. J. HOLT, Auteur ; H. HAYWARD, Auteur ; D. MURPHY, Auteur ; B. OAKLEY, Auteur ; T. CHARMAN, Auteur ; J. AHMAD, Auteur ; S. BARON-COHEN, Auteur ; M.H. JOHNSON, Auteur ; T. BANASCHEWSKI, Auteur ; S. DURSTON, Auteur ; B. ORANJE, Auteur ; S. BÖLTE, Auteur ; J. BUITELAAR, Auteur ; P. J. HOEKSTRA, Auteur ; A. DIETRICH, Auteur ; E. U. Aims Leap group THE, Auteur . - p.2557-2573. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 56-7 (July 2026) . - p.2557-2573 Index. décimale : PER Périodiques Résumé : Autism has been associated with differences in functional brain network organization. However, the exact nature of these differences across development compared to non-autistic individuals and their relationship to autism-related social cognition, remains unclear. This study first aimed to identify EEG resting-state network characteristics in autistic versus non-autistic children, adolescents, and adults. Second, we investigated associations with social cognition measures. Analyzing resting-state EEG data from the EU-AIMS Longitudinal European Autism Project, we compared network metrics (global efficiency, clustering coefficient, and small-worldness) between 344 autistic and non-autistic individuals within and across age groups in four frequency bands (delta, theta, alpha, and beta). If significant, we explored their relationships to measures of empathy (empathy quotient), complex emotion recognition [reading the mind in the eyes task (RMET)], and theory of mind (animated shapes task). Compared to their non-autistic peers, autistic adolescents showed lower alpha global efficiency, while autistic adults showed lower alpha clustering and small-worldness. No network differences were observed among children. In adolescents, higher long-range integration was tentatively associated with higher RMET scores; in those with high autistic traits, higher long-range integration related to fewer parent-reported empathic behaviors. No brain-behavior relationships were observed in adults. Our findings suggest subtle differences in network topology between autistic and non-autistic individuals, with less efficient long-range efficiency during adolescence, and less local and overall network efficiency in adulthood. Furthermore, long-range integration may play a role in complex emotion recognition and empathy difficulties associated with autism in adolescence. En ligne : https://doi.org/10.1007/s10803-025-06731-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=590

Occurrence and Correlates of Suicidal Thoughts Among Young Autistic Users of a Mental Health App / T.L. PROCYSHYN in Autism Research, 19-6 (June 2026)  

Public ISBD [article]  inAutism Research > 19-6 (June 2026) . - p.e70251 Titre : Occurrence and Correlates of Suicidal Thoughts Among Young Autistic Users of a Mental Health App Type de document : texte imprimé Auteurs : T.L. PROCYSHYN, Auteur ; E.M. WEIR, Auteur ; M. PELTON, Auteur ; T. CHIKAURA, Auteur ; H. HODGES, Auteur ; K. COMLEY, Auteur ; S. GODSON, Auteur ; C. ALLISON, Auteur ; S. BARON-COHEN, Auteur Article en page(s) : p.e70251 Langues : Anglais (eng) Mots-clés : autism  depression  mental health  self-harm  suicide Index. décimale : PER Périodiques Résumé : ABSTRACT Young autistic people experience disproportionately high rates of mental health challenges, yet little is known about factors associated with suicidality in this group. This study leveraged anonymous self-report data to identify correlates of suicidal thoughts among 365 young users (aged approximately 11?25?years) of a mental health app in the United Kingdom with an autism diagnosis or self-identifying as autistic. The presence of suicidal thoughts was assessed as a binary item. Binary logistic regression was used to explore correlates of suicidal thoughts across three domains: mental health-related symptoms, autism-related factors, and adverse life events/experiences. The final model included all significant correlates from domain-specific models alongside demographic factors. Suicidal thoughts were reported by 63% of participants, with similar rates across age groups. The final model accounted for nearly 50% of variability in the presence of suicidal thoughts (R 2 Nagelkerke?=?0.48, p? En ligne : https://doi.org/10.1002/aur.70251 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=589 [article] Occurrence and Correlates of Suicidal Thoughts Among Young Autistic Users of a Mental Health App [texte imprimé] / T.L. PROCYSHYN, Auteur ; E.M. WEIR, Auteur ; M. PELTON, Auteur ; T. CHIKAURA, Auteur ; H. HODGES, Auteur ; K. COMLEY, Auteur ; S. GODSON, Auteur ; C. ALLISON, Auteur ; S. BARON-COHEN, Auteur . - p.e70251. Langues : Anglais (eng) in Autism Research > 19-6 (June 2026) . - p.e70251 Mots-clés : autism  depression  mental health  self-harm  suicide Index. décimale : PER Périodiques Résumé : ABSTRACT Young autistic people experience disproportionately high rates of mental health challenges, yet little is known about factors associated with suicidality in this group. This study leveraged anonymous self-report data to identify correlates of suicidal thoughts among 365 young users (aged approximately 11?25?years) of a mental health app in the United Kingdom with an autism diagnosis or self-identifying as autistic. The presence of suicidal thoughts was assessed as a binary item. Binary logistic regression was used to explore correlates of suicidal thoughts across three domains: mental health-related symptoms, autism-related factors, and adverse life events/experiences. The final model included all significant correlates from domain-specific models alongside demographic factors. Suicidal thoughts were reported by 63% of participants, with similar rates across age groups. The final model accounted for nearly 50% of variability in the presence of suicidal thoughts (R 2 Nagelkerke?=?0.48, p? En ligne : https://doi.org/10.1002/aur.70251 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=589

Traumatic Experiences, Psychological Distress and Suicide-Related Behaviors in Autistic Adults / T. A. CHIKAURA in Autism Research, 19-1 (January 2026)  

Public ISBD [article]  inAutism Research > 19-1 (January 2026) . - p.e70137 Titre : Traumatic Experiences, Psychological Distress and Suicide-Related Behaviors in Autistic Adults Type de document : texte imprimé Auteurs : T. A. CHIKAURA, Auteur ; E. WEIR, Auteur ; S. GRIFFITHS, Auteur ; T. PROCYSHYN, Auteur ; M. PELTON, Auteur ; C. ALLISON, Auteur ; H. HODGES, Auteur ; S. R. WHITE, Auteur ; T. FORD, Auteur ; S. BARON-COHEN, Auteur Article en page(s) : p.e70137 Langues : Anglais (eng) Mots-clés : autism  mental health  self-harm  substance use  suicide attempts  suicide plans  trauma Index. décimale : PER Périodiques Résumé : ABSTRACT Autistic adults have increased risks of trauma, suicide, and poor mental health compared to non-autistic adults, with 1 in 4 autistic adults attempting suicide. We administered an anonymized, self-report survey to 424 autistic and 345 non-autistic adults through a convenience sampling framework. Binomial logistic regression models identified whether trauma and autism diagnosis were related to (i) self-harm, (ii) suicide attempts, (iii) suicide plans, (iv) a mental health condition that impacts daily life, and (v) substance use to cope. Heatmaps were generated to identify traumas that frequently co-occur with psychological distress and SRB. After accounting for trauma and demographic differences, autism remained a significant predictor of all outcomes, except whether individuals used substances to cope (OR: 0.78, 95% CI: 0.54?1.12, p?=?0.18). Autistic people were more likely to report self-harm (OR: 2.71, 95% CI: 1.85?4.00, p? En ligne : https://doi.org/10.1002/aur.70137 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=578 [article] Traumatic Experiences, Psychological Distress and Suicide-Related Behaviors in Autistic Adults [texte imprimé] / T. A. CHIKAURA, Auteur ; E. WEIR, Auteur ; S. GRIFFITHS, Auteur ; T. PROCYSHYN, Auteur ; M. PELTON, Auteur ; C. ALLISON, Auteur ; H. HODGES, Auteur ; S. R. WHITE, Auteur ; T. FORD, Auteur ; S. BARON-COHEN, Auteur . - p.e70137. Langues : Anglais (eng) in Autism Research > 19-1 (January 2026) . - p.e70137 Mots-clés : autism  mental health  self-harm  substance use  suicide attempts  suicide plans  trauma Index. décimale : PER Périodiques Résumé : ABSTRACT Autistic adults have increased risks of trauma, suicide, and poor mental health compared to non-autistic adults, with 1 in 4 autistic adults attempting suicide. We administered an anonymized, self-report survey to 424 autistic and 345 non-autistic adults through a convenience sampling framework. Binomial logistic regression models identified whether trauma and autism diagnosis were related to (i) self-harm, (ii) suicide attempts, (iii) suicide plans, (iv) a mental health condition that impacts daily life, and (v) substance use to cope. Heatmaps were generated to identify traumas that frequently co-occur with psychological distress and SRB. After accounting for trauma and demographic differences, autism remained a significant predictor of all outcomes, except whether individuals used substances to cope (OR: 0.78, 95% CI: 0.54?1.12, p?=?0.18). Autistic people were more likely to report self-harm (OR: 2.71, 95% CI: 1.85?4.00, p? En ligne : https://doi.org/10.1002/aur.70137 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=578

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