[article]
| Titre : |
Smartphone language and resting-state EEG indicators of self-focused attention prospectively predict major depressive disorder risk in adolescents |
| Type de document : |
texte imprimé |
| Auteurs : |
Lilian Y. LI, Auteur ; Nayoung KIM, Auteur ; Esha TRIVEDI, Auteur ; Sarah E. SARKAS, Auteur ; Madeline M. MCGREGOR, Auteur ; Aishwarya SRITHARAN, Auteur ; Katherine DURHAM, Auteur ; Ivan ALEKSEICHUK, Auteur ; Allison M. LETKIEWICZ, Auteur ; Vijay A. MITTAL, Auteur ; David PAGLIACCIO, Auteur ; Nicholas B. ALLEN, Auteur ; Randy P. AUERBACH, Auteur ; Stewart A. SHANKMAN, Auteur |
| Article en page(s) : |
p.941-950 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Depression adolescence self-focused attention digital phenotyping EEG alpha oscillations |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Background Central to major depressive disorder (MDD) onset and maintenance is maladaptive self-focused attention, which can be reliably indexed by greater: (a) usage of first-person singular pronouns (e.g., I) in natural language and (b) alpha oscillations in resting-state EEG. Integrating these largely parallel bodies of research, the present study sought to explicate the associations between, and prospective predictive utility of, linguistic and neural indicators of self-focused attention in adolescents with remitted MDD over 12?months. Methods At baseline, 126 adolescents (ages 13?18) with (n?=?66) and without (n?=?60) remitted MDD completed resting-state EEG. Retrospective interviews determined the occurrence of major depressive episodes (MDEs) during the follow-up period. A total of ~2.3?million messages were passively acquired from adolescents' smartphones, on which the proportion of first-person singular pronouns was derived. Results During the 12?months, 29 (23.0%) participants developed an MDE (28 remitted MDD, 1 control). Cox regression showed that while greater usage of first-person singular pronouns prior to MDE increased the risk for MDE (hazard ratio [HR]?=?2.02, p?.001), greater resting-state alpha power at baseline decreased the risk for MDE (HR?=?0.78, p?=?.001). Moreover, greater alpha power predicted subsequent first-person singular pronoun usage (??=?0.17, p?=?.004). Mediation analysis indicated a marginal suppression effect (bootstrapped indirect effect p?.10), such that accounting for first-person singular pronoun usage amplified the association between alpha power and MDE risk. Conclusions Findings highlight functionally distinct alpha mechanisms and provide support for smartphone-based first-person singular pronoun usage as a neurobehavioral risk factor and a potentially promising intervention target for adolescent MDD. |
| En ligne : |
https://doi.org/10.1111/jcpp.70096 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 |
in Journal of Child Psychology and Psychiatry > 67-6 (June 2026) . - p.941-950
[article] Smartphone language and resting-state EEG indicators of self-focused attention prospectively predict major depressive disorder risk in adolescents [texte imprimé] / Lilian Y. LI, Auteur ; Nayoung KIM, Auteur ; Esha TRIVEDI, Auteur ; Sarah E. SARKAS, Auteur ; Madeline M. MCGREGOR, Auteur ; Aishwarya SRITHARAN, Auteur ; Katherine DURHAM, Auteur ; Ivan ALEKSEICHUK, Auteur ; Allison M. LETKIEWICZ, Auteur ; Vijay A. MITTAL, Auteur ; David PAGLIACCIO, Auteur ; Nicholas B. ALLEN, Auteur ; Randy P. AUERBACH, Auteur ; Stewart A. SHANKMAN, Auteur . - p.941-950. Langues : Anglais ( eng) in Journal of Child Psychology and Psychiatry > 67-6 (June 2026) . - p.941-950
| Mots-clés : |
Depression adolescence self-focused attention digital phenotyping EEG alpha oscillations |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Background Central to major depressive disorder (MDD) onset and maintenance is maladaptive self-focused attention, which can be reliably indexed by greater: (a) usage of first-person singular pronouns (e.g., I) in natural language and (b) alpha oscillations in resting-state EEG. Integrating these largely parallel bodies of research, the present study sought to explicate the associations between, and prospective predictive utility of, linguistic and neural indicators of self-focused attention in adolescents with remitted MDD over 12?months. Methods At baseline, 126 adolescents (ages 13?18) with (n?=?66) and without (n?=?60) remitted MDD completed resting-state EEG. Retrospective interviews determined the occurrence of major depressive episodes (MDEs) during the follow-up period. A total of ~2.3?million messages were passively acquired from adolescents' smartphones, on which the proportion of first-person singular pronouns was derived. Results During the 12?months, 29 (23.0%) participants developed an MDE (28 remitted MDD, 1 control). Cox regression showed that while greater usage of first-person singular pronouns prior to MDE increased the risk for MDE (hazard ratio [HR]?=?2.02, p?.001), greater resting-state alpha power at baseline decreased the risk for MDE (HR?=?0.78, p?=?.001). Moreover, greater alpha power predicted subsequent first-person singular pronoun usage (??=?0.17, p?=?.004). Mediation analysis indicated a marginal suppression effect (bootstrapped indirect effect p?.10), such that accounting for first-person singular pronoun usage amplified the association between alpha power and MDE risk. Conclusions Findings highlight functionally distinct alpha mechanisms and provide support for smartphone-based first-person singular pronoun usage as a neurobehavioral risk factor and a potentially promising intervention target for adolescent MDD. |
| En ligne : |
https://doi.org/10.1111/jcpp.70096 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=587 |
|  |