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Auteur Lindsay OLSON |
Documents disponibles écrits par cet auteur (2)
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Greater functional connectivity between sensory networks is related to symptom severity in toddlers with autism spectrum disorder / Bosi CHEN in Journal of Child Psychology and Psychiatry, 62-2 (February 2021)
[article]
Titre : Greater functional connectivity between sensory networks is related to symptom severity in toddlers with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Bosi CHEN, Auteur ; Annika LINKE, Auteur ; Lindsay OLSON, Auteur ; Cynthia IBARRA, Auteur ; Sarah REYNOLDS, Auteur ; Ralph-Axel MULLER, Auteur ; Mikaela KINNEAR, Auteur ; Inna FISHMAN, Auteur Année de publication : 2021 Article en page(s) : p.160-170 Langues : Anglais (eng) Mots-clés : Brain networks autism spectrum disorders early childhood functional connectivity neuroimaging Index. décimale : PER Périodiques Résumé : BACKGROUND: Symptoms of autism spectrum disorder (ASD) emerge in the first years of life. Yet, little is known about the organization and development of functional brain networks in ASD proximally to the symptom onset. Further, the relationship between brain network connectivity and emerging ASD symptoms and overall functioning in early childhood is not well understood. METHODS: Resting-state fMRI data were acquired during natural sleep from 24 young children with ASD and 23 typically developing (TD) children, aged 17-45 months. Intrinsic functional connectivity (iFC) within and between resting-state functional networks was derived with independent component analysis (ICA). RESULTS: Increased iFC between visual and sensorimotor networks was found in young children with ASD compared to TD participants. Within the ASD group, the degree of overconnectivity between visual and sensorimotor networks was associated with greater autism symptoms. Age-related weakening of the visual-auditory between-network connectivity was observed in the ASD but not the TD group. CONCLUSIONS: Taken together, these results provide evidence for disrupted functional network maturation and differentiation, particularly involving visual and sensorimotor networks, during the first years of life in ASD. The observed pattern of greater visual-sensorimotor between-network connectivity associated with poorer clinical outcomes suggests that disruptions in multisensory brain circuitry may play a critical role for early development of behavioral skills and autism symptomatology in young children with ASD. En ligne : http://dx.doi.org/10.1111/jcpp.13268 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=440
in Journal of Child Psychology and Psychiatry > 62-2 (February 2021) . - p.160-170[article] Greater functional connectivity between sensory networks is related to symptom severity in toddlers with autism spectrum disorder [Texte imprimé et/ou numérique] / Bosi CHEN, Auteur ; Annika LINKE, Auteur ; Lindsay OLSON, Auteur ; Cynthia IBARRA, Auteur ; Sarah REYNOLDS, Auteur ; Ralph-Axel MULLER, Auteur ; Mikaela KINNEAR, Auteur ; Inna FISHMAN, Auteur . - 2021 . - p.160-170.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 62-2 (February 2021) . - p.160-170
Mots-clés : Brain networks autism spectrum disorders early childhood functional connectivity neuroimaging Index. décimale : PER Périodiques Résumé : BACKGROUND: Symptoms of autism spectrum disorder (ASD) emerge in the first years of life. Yet, little is known about the organization and development of functional brain networks in ASD proximally to the symptom onset. Further, the relationship between brain network connectivity and emerging ASD symptoms and overall functioning in early childhood is not well understood. METHODS: Resting-state fMRI data were acquired during natural sleep from 24 young children with ASD and 23 typically developing (TD) children, aged 17-45 months. Intrinsic functional connectivity (iFC) within and between resting-state functional networks was derived with independent component analysis (ICA). RESULTS: Increased iFC between visual and sensorimotor networks was found in young children with ASD compared to TD participants. Within the ASD group, the degree of overconnectivity between visual and sensorimotor networks was associated with greater autism symptoms. Age-related weakening of the visual-auditory between-network connectivity was observed in the ASD but not the TD group. CONCLUSIONS: Taken together, these results provide evidence for disrupted functional network maturation and differentiation, particularly involving visual and sensorimotor networks, during the first years of life in ASD. The observed pattern of greater visual-sensorimotor between-network connectivity associated with poorer clinical outcomes suggests that disruptions in multisensory brain circuitry may play a critical role for early development of behavioral skills and autism symptomatology in young children with ASD. En ligne : http://dx.doi.org/10.1111/jcpp.13268 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=440 Uh and um in children with autism spectrum disorders or language impairment / Kyle GORMAN in Autism Research, 9-8 (August 2016)
[article]
Titre : Uh and um in children with autism spectrum disorders or language impairment Type de document : Texte imprimé et/ou numérique Auteurs : Kyle GORMAN, Auteur ; Lindsay OLSON, Auteur ; Alison Presmanes HILL, Auteur ; Rebecca LUNSFORD, Auteur ; Peter A. HEEMAN, Auteur ; Jan P. H. VAN SANTEN, Auteur Article en page(s) : p.854-865 Langues : Anglais (eng) Mots-clés : autism spectrum disorders language impairment social communication conversational reciprocity pragmatic language disfluency fillers Index. décimale : PER Périodiques Résumé : Atypical pragmatic language is often present in individuals with autism spectrum disorders (ASD), along with delays or deficits in structural language. This study investigated the use of the “fillers” uh and um by children ages 4–8 during the autism diagnostic observation schedule. Fillers reflect speakers' difficulties with planning and delivering speech, but they also serve communicative purposes, such as negotiating control of the floor or conveying uncertainty. We hypothesized that children with ASD would use different patterns of fillers compared to peers with typical development or with specific language impairment (SLI), reflecting differences in social ability and communicative intent. Regression analyses revealed that children in the ASD group were much less likely to use um than children in the other two groups. Filler use is an easy-to-quantify feature of behavior that, in concert with other observations, may help to distinguish ASD from SLI. Autism Res 2016, 9: 854–865. © 2016 En ligne : http://dx.doi.org/10.1002/aur.1578 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=293
in Autism Research > 9-8 (August 2016) . - p.854-865[article] Uh and um in children with autism spectrum disorders or language impairment [Texte imprimé et/ou numérique] / Kyle GORMAN, Auteur ; Lindsay OLSON, Auteur ; Alison Presmanes HILL, Auteur ; Rebecca LUNSFORD, Auteur ; Peter A. HEEMAN, Auteur ; Jan P. H. VAN SANTEN, Auteur . - p.854-865.
Langues : Anglais (eng)
in Autism Research > 9-8 (August 2016) . - p.854-865
Mots-clés : autism spectrum disorders language impairment social communication conversational reciprocity pragmatic language disfluency fillers Index. décimale : PER Périodiques Résumé : Atypical pragmatic language is often present in individuals with autism spectrum disorders (ASD), along with delays or deficits in structural language. This study investigated the use of the “fillers” uh and um by children ages 4–8 during the autism diagnostic observation schedule. Fillers reflect speakers' difficulties with planning and delivering speech, but they also serve communicative purposes, such as negotiating control of the floor or conveying uncertainty. We hypothesized that children with ASD would use different patterns of fillers compared to peers with typical development or with specific language impairment (SLI), reflecting differences in social ability and communicative intent. Regression analyses revealed that children in the ASD group were much less likely to use um than children in the other two groups. Filler use is an easy-to-quantify feature of behavior that, in concert with other observations, may help to distinguish ASD from SLI. Autism Res 2016, 9: 854–865. © 2016 En ligne : http://dx.doi.org/10.1002/aur.1578 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=293