76 recherche sur le mot-clé 'neuroimaging'

Neuroimaging genetics and developmental psychopathology: A systematic review / Connor L. CHEEK in Development and Psychopathology, 37-5 (December 2025)  

Public ISBD [article]  inDevelopment and Psychopathology > 37-5 (December 2025) . - p.2772-2794 Titre : Neuroimaging genetics and developmental psychopathology: A systematic review Type de document : texte imprimé Auteurs : Connor L. CHEEK, Auteur ; Pavel V. DOBRYNIN, Auteur ; Galina V. KHAFIZOVA, Auteur ; Nabin KOIRALA, Auteur ; Kelly MAHAFFY, Auteur ; Elena L. GRIGORENKO, Auteur Article en page(s) : p.2772-2794 Langues : Anglais (eng) Mots-clés : Imaging genetics  neurodevelopmental disorders  neuroimaging  psychopathology Index. décimale : PER Périodiques Résumé : Imaging genetics is an interdisciplinary field that integrates neuroimaging and genetic data to improve behavioral prediction and investigate the genetic bases of brain structure and function. It aims to identify associations between genetic markers and brain imaging phenotypes, with a behavioral or clinical trait as the outcome of interest. Since its emergence nearly 30 years ago, the field has advanced substantially, fueled by rapid developments in molecular-genetic and neuroimaging techniques. These advances have opened new avenues for exploring individual differences in cognitive and socio-emotional development and their links to neurodevelopmental disorders. This systematic review examined studies published between 2020 and 2024, focusing on developmental psychopathology. We screened 769 articles from PubMed/MEDLINE and PsycINFO and selected 42 publications that met specific inclusion criteria for review. The studies were categorized into three groups based on the developmental ages in which conditions typically develop: birth/early childhood, late childhood or early adolescence, and late adolescence. Although the field has seen considerable progress, multiple challenges in data acquisition, analysis, and interpretation remain. Larger sample sizes and novel analytical techniques are crucial for the continued advancement of imaging genetics, with animal studies offering potential complementary insights. En ligne : https://dx.doi.org/10.1017/S0954579425100400 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=572 [article] Neuroimaging genetics and developmental psychopathology: A systematic review [texte imprimé] / Connor L. CHEEK, Auteur ; Pavel V. DOBRYNIN, Auteur ; Galina V. KHAFIZOVA, Auteur ; Nabin KOIRALA, Auteur ; Kelly MAHAFFY, Auteur ; Elena L. GRIGORENKO, Auteur . - p.2772-2794. Langues : Anglais (eng) in Development and Psychopathology > 37-5 (December 2025) . - p.2772-2794 Mots-clés : Imaging genetics  neurodevelopmental disorders  neuroimaging  psychopathology Index. décimale : PER Périodiques Résumé : Imaging genetics is an interdisciplinary field that integrates neuroimaging and genetic data to improve behavioral prediction and investigate the genetic bases of brain structure and function. It aims to identify associations between genetic markers and brain imaging phenotypes, with a behavioral or clinical trait as the outcome of interest. Since its emergence nearly 30 years ago, the field has advanced substantially, fueled by rapid developments in molecular-genetic and neuroimaging techniques. These advances have opened new avenues for exploring individual differences in cognitive and socio-emotional development and their links to neurodevelopmental disorders. This systematic review examined studies published between 2020 and 2024, focusing on developmental psychopathology. We screened 769 articles from PubMed/MEDLINE and PsycINFO and selected 42 publications that met specific inclusion criteria for review. The studies were categorized into three groups based on the developmental ages in which conditions typically develop: birth/early childhood, late childhood or early adolescence, and late adolescence. Although the field has seen considerable progress, multiple challenges in data acquisition, analysis, and interpretation remain. Larger sample sizes and novel analytical techniques are crucial for the continued advancement of imaging genetics, with animal studies offering potential complementary insights. En ligne : https://dx.doi.org/10.1017/S0954579425100400 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=572

Neuroimaging research with diverse children with ASD: Impact of a social story on parent understanding and likelihood of participation / Ainsley LOSH in Research in Autism Spectrum Disorders, 71 (March 2020)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 71 (March 2020) . - p.101511 Titre : Neuroimaging research with diverse children with ASD: Impact of a social story on parent understanding and likelihood of participation Type de document : texte imprimé Auteurs : Ainsley LOSH, Auteur ; Laura Alicia ALBA, Auteur ; Jan BLACHER, Auteur ; Katherine K.M. STAVROPOULOS, Auteur Article en page(s) : p.101511 Langues : Anglais (eng) Mots-clés : Autism  ASD  Neuroimaging  EEG  Social stories  Informed consent Index. décimale : PER Périodiques Résumé : Background The successful inclusion of youth with autism spectrum disorder (ASD) in neuroimaging research is imperative for advancing our understanding of the neurobiological underpinnings of ASD. In order to generate knowledge that is representative of all affected youth, it is essential to include participants who are culturally and linguistically diverse. However, these families often face barriers to participation in neuroimaging research, including distrust and limited knowledge about research, above and beyond any challenges associated with ASD (e.g., behaviors, sensory hypersensitivities). Method This study included a diverse group of Spanish- and English-speaking parents of children with ASD (N = 79) to examine the impact of a social story on (a) their understanding of EEG study procedures and (b) their likelihood to enroll in a neuroimaging study. Results Both English- and Spanish-speaking parents who viewed a social story demonstrated better understanding of EEG procedures than parents who read a written explanation, with Spanish-speaking parents also perceiving their understanding to be better in the social story condition. Although parents who viewed a social story were not more likely to participate in neuroimaging research than parents who read a written description, they were less likely to indicate needing more information and more likely to cite their child’s specific behavior problems as the rationale for unlikelihood to participate. Conclusion These results suggest that social stories may be effective tools in the informed consent process for promoting parent understanding of neuroimaging procedures, and useful during recruitment to aid parents in determining whether their child with ASD will be successful in a neuroimaging study. En ligne : https://doi.org/10.1016/j.rasd.2020.101511 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=417 [article] Neuroimaging research with diverse children with ASD: Impact of a social story on parent understanding and likelihood of participation [texte imprimé] / Ainsley LOSH, Auteur ; Laura Alicia ALBA, Auteur ; Jan BLACHER, Auteur ; Katherine K.M. STAVROPOULOS, Auteur . - p.101511. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 71 (March 2020) . - p.101511 Mots-clés : Autism  ASD  Neuroimaging  EEG  Social stories  Informed consent Index. décimale : PER Périodiques Résumé : Background The successful inclusion of youth with autism spectrum disorder (ASD) in neuroimaging research is imperative for advancing our understanding of the neurobiological underpinnings of ASD. In order to generate knowledge that is representative of all affected youth, it is essential to include participants who are culturally and linguistically diverse. However, these families often face barriers to participation in neuroimaging research, including distrust and limited knowledge about research, above and beyond any challenges associated with ASD (e.g., behaviors, sensory hypersensitivities). Method This study included a diverse group of Spanish- and English-speaking parents of children with ASD (N = 79) to examine the impact of a social story on (a) their understanding of EEG study procedures and (b) their likelihood to enroll in a neuroimaging study. Results Both English- and Spanish-speaking parents who viewed a social story demonstrated better understanding of EEG procedures than parents who read a written explanation, with Spanish-speaking parents also perceiving their understanding to be better in the social story condition. Although parents who viewed a social story were not more likely to participate in neuroimaging research than parents who read a written description, they were less likely to indicate needing more information and more likely to cite their child’s specific behavior problems as the rationale for unlikelihood to participate. Conclusion These results suggest that social stories may be effective tools in the informed consent process for promoting parent understanding of neuroimaging procedures, and useful during recruitment to aid parents in determining whether their child with ASD will be successful in a neuroimaging study. En ligne : https://doi.org/10.1016/j.rasd.2020.101511 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=417

Annual Research Review: Understudied populations within the autism spectrum – current trends and future directions in neuroimaging research / Allison JACK in Journal of Child Psychology and Psychiatry, 58-4 (April 2017)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 58-4 (April 2017) . - p.411-435 Titre : Annual Research Review: Understudied populations within the autism spectrum – current trends and future directions in neuroimaging research Type de document : texte imprimé Auteurs : Allison JACK, Auteur ; Kevin A. PELPHREY, Auteur Article en page(s) : p.411-435 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  intellectual disability  neuroimaging Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental conditions that vary in both etiology and phenotypic expression. Expressions of ASD characterized by a more severe phenotype, including autism with intellectual disability (ASD + ID), autism with a history of developmental regression (ASD + R), and minimally verbal autism (ASD + MV) are understudied generally, and especially in the domain of neuroimaging. However, neuroimaging methods are a potentially powerful tool for understanding the etiology of these ASD subtypes. Scope and methodology This review evaluates existing neuroimaging research on ASD + MV, ASD + ID, and ASD + R, identified by a search of the literature using the PubMed database, and discusses methodological, theoretical, and practical considerations for future research involving neuroimaging assessment of these populations. Findings There is a paucity of neuroimaging research on ASD + ID, ASD + MV, and ASD + R, and what findings do exist are often contradictory, or so sparse as to be ungeneralizable. We suggest that while greater sample sizes and more studies are necessary, more important would be a paradigm shift toward multimodal (e.g. imaging genetics) approaches that allow for the characterization of heterogeneity within etiologically diverse samples. En ligne : http://dx.doi.org/10.1111/jcpp.12687 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305 [article] Annual Research Review: Understudied populations within the autism spectrum – current trends and future directions in neuroimaging research [texte imprimé] / Allison JACK, Auteur ; Kevin A. PELPHREY, Auteur . - p.411-435. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 58-4 (April 2017) . - p.411-435 Mots-clés : Autism spectrum disorders  intellectual disability  neuroimaging Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental conditions that vary in both etiology and phenotypic expression. Expressions of ASD characterized by a more severe phenotype, including autism with intellectual disability (ASD + ID), autism with a history of developmental regression (ASD + R), and minimally verbal autism (ASD + MV) are understudied generally, and especially in the domain of neuroimaging. However, neuroimaging methods are a potentially powerful tool for understanding the etiology of these ASD subtypes. Scope and methodology This review evaluates existing neuroimaging research on ASD + MV, ASD + ID, and ASD + R, identified by a search of the literature using the PubMed database, and discusses methodological, theoretical, and practical considerations for future research involving neuroimaging assessment of these populations. Findings There is a paucity of neuroimaging research on ASD + ID, ASD + MV, and ASD + R, and what findings do exist are often contradictory, or so sparse as to be ungeneralizable. We suggest that while greater sample sizes and more studies are necessary, more important would be a paradigm shift toward multimodal (e.g. imaging genetics) approaches that allow for the characterization of heterogeneity within etiologically diverse samples. En ligne : http://dx.doi.org/10.1111/jcpp.12687 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305

Are schizophrenia, autistic, and obsessive spectrum disorders dissociable on the basis of neuroimaging morphological findings?: A voxel-based meta-analysis / Franco CAUDA in Autism Research, 10-6 (June 2017)  

Public ISBD [article]  inAutism Research > 10-6 (June 2017) . - p.1079-1095 Titre : Are schizophrenia, autistic, and obsessive spectrum disorders dissociable on the basis of neuroimaging morphological findings?: A voxel-based meta-analysis Type de document : texte imprimé Auteurs : Franco CAUDA, Auteur ; Tommaso COSTA, Auteur ; Andrea NANI, Auteur ; Luciano FAVA, Auteur ; Sara PALERMO, Auteur ; Francesca BIANCO, Auteur ; Sergio DUCA, Auteur ; Karina TATU, Auteur ; Roberto KELLER, Auteur Article en page(s) : p.1079-1095 Langues : Anglais (eng) Mots-clés : brain alterations  neuroimaging  schizophrenia spectrum disorder  autism spectrum disorder  obsessive-compulsive spectrum disorder  psychiatric categories  core alterations Index. décimale : PER Périodiques Résumé : Schizophrenia spectrum disorder (SCZD), autism spectrum disorder (ASD), and obsessive-compulsive spectrum disorder (OCSD) are considered as three separate psychiatric conditions with, supposedly, different brain alterations patterns. From a neuroimaging perspective, this meta-analytic study aimed to address whether this nosographical differentiation is actually supported by different brain patterns of gray matter (GM) or white matter (WM) morphological alterations. We explored two possibilities: (a) to find out whether GM alterations are specific for SCZD, ASD, and OCSD; and (b) to associate the identified brain alteration patterns with cognitive dysfunctions by means of an analysis of lesion decoding. Our analysis reveals that these psychiatric spectra do not present clear distinctive patterns of alterations; rather, they all tend to be distributed in two alteration clusters. Cluster 1, which is more specific for SCZD, includes the anterior insular, anterior cingulate cortex, ventromedial prefrontal cortex, and frontopolar areas, which are parts of the cognitive control system. Cluster 2, which is more specific for OCSD, presents occipital, temporal, and parietal alteration patterns with the involvement of sensorimotor, premotor, visual, and lingual areas, thus forming a network that is more associated with the auditory-visual, auditory, premotor visual somatic functions. In turn, ASD appears to be uniformly distributed in the two clusters. The three spectra share a significant set of alterations. Our new approach promises to provide insight into the understanding of psychiatric conditions under the aspect of a common neurobiological substrate, possibly related to neuroinflammation during brain development. En ligne : http://dx.doi.org/10.1002/aur.1759 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=309 [article] Are schizophrenia, autistic, and obsessive spectrum disorders dissociable on the basis of neuroimaging morphological findings?: A voxel-based meta-analysis [texte imprimé] / Franco CAUDA, Auteur ; Tommaso COSTA, Auteur ; Andrea NANI, Auteur ; Luciano FAVA, Auteur ; Sara PALERMO, Auteur ; Francesca BIANCO, Auteur ; Sergio DUCA, Auteur ; Karina TATU, Auteur ; Roberto KELLER, Auteur . - p.1079-1095. Langues : Anglais (eng) in Autism Research > 10-6 (June 2017) . - p.1079-1095 Mots-clés : brain alterations  neuroimaging  schizophrenia spectrum disorder  autism spectrum disorder  obsessive-compulsive spectrum disorder  psychiatric categories  core alterations Index. décimale : PER Périodiques Résumé : Schizophrenia spectrum disorder (SCZD), autism spectrum disorder (ASD), and obsessive-compulsive spectrum disorder (OCSD) are considered as three separate psychiatric conditions with, supposedly, different brain alterations patterns. From a neuroimaging perspective, this meta-analytic study aimed to address whether this nosographical differentiation is actually supported by different brain patterns of gray matter (GM) or white matter (WM) morphological alterations. We explored two possibilities: (a) to find out whether GM alterations are specific for SCZD, ASD, and OCSD; and (b) to associate the identified brain alteration patterns with cognitive dysfunctions by means of an analysis of lesion decoding. Our analysis reveals that these psychiatric spectra do not present clear distinctive patterns of alterations; rather, they all tend to be distributed in two alteration clusters. Cluster 1, which is more specific for SCZD, includes the anterior insular, anterior cingulate cortex, ventromedial prefrontal cortex, and frontopolar areas, which are parts of the cognitive control system. Cluster 2, which is more specific for OCSD, presents occipital, temporal, and parietal alteration patterns with the involvement of sensorimotor, premotor, visual, and lingual areas, thus forming a network that is more associated with the auditory-visual, auditory, premotor visual somatic functions. In turn, ASD appears to be uniformly distributed in the two clusters. The three spectra share a significant set of alterations. Our new approach promises to provide insight into the understanding of psychiatric conditions under the aspect of a common neurobiological substrate, possibly related to neuroinflammation during brain development. En ligne : http://dx.doi.org/10.1002/aur.1759 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=309

Autism spectrum disorders: Neuroimaging findings from systematic reviews / Emmanuel Peng Kiat PUA in Research in Autism Spectrum Disorders, 34 (February 2017)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 34 (February 2017) . - p.28-33 Titre : Autism spectrum disorders: Neuroimaging findings from systematic reviews Type de document : texte imprimé Auteurs : Emmanuel Peng Kiat PUA, Auteur ; Stephen C. BOWDEN, Auteur ; Marc L. SEAL, Auteur Article en page(s) : p.28-33 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Brain structure  Brain function  Brain connectivity  Neuroimaging  Magnetic resonance imaging Index. décimale : PER Périodiques Résumé : Abstract Autism Spectrum Disorders (ASD) are a cluster of neurodevelopmental conditions associated with core deficits in social communication, social interaction, and restricted and repetitive behaviours. Current evidence suggests a complex interaction between genetic and environmental factors that underlie the heterogeneity of neuroanatomy and clinical symptomatology of ASD across a spectrum. Although abnormalities in brain structure and function have been implicated in the neurodevelopmental trajectory of ASD, the search for definitive neuroimaging markers remains obscured by inconsistent or incompatible findings. Specifically, discrepancies between independent studies impede reliable identification of the nature and form of atypical alterations in grey-matter structural morphometry and intrinsic functional networks in ASD. This review aims to illustrate the heterogeneity in ASD neuroimaging literature by comparing systematic reviews and meta-analyses of neuroimaging investigations in ASD over the last several decades, with particular emphasis on structural morphometry, structural connectivity and resting-state intrinsic connectivity techniques. Given the unique challenges in ASD research, standardized methodologies to validate potential neuroimaging markers will be an important step towards advancing clinical and research methods to investigate complex aetiological mechanisms and risk factors underlying ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.11.005 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298 [article] Autism spectrum disorders: Neuroimaging findings from systematic reviews [texte imprimé] / Emmanuel Peng Kiat PUA, Auteur ; Stephen C. BOWDEN, Auteur ; Marc L. SEAL, Auteur . - p.28-33. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 34 (February 2017) . - p.28-33 Mots-clés : Autism spectrum disorders  Brain structure  Brain function  Brain connectivity  Neuroimaging  Magnetic resonance imaging Index. décimale : PER Périodiques Résumé : Abstract Autism Spectrum Disorders (ASD) are a cluster of neurodevelopmental conditions associated with core deficits in social communication, social interaction, and restricted and repetitive behaviours. Current evidence suggests a complex interaction between genetic and environmental factors that underlie the heterogeneity of neuroanatomy and clinical symptomatology of ASD across a spectrum. Although abnormalities in brain structure and function have been implicated in the neurodevelopmental trajectory of ASD, the search for definitive neuroimaging markers remains obscured by inconsistent or incompatible findings. Specifically, discrepancies between independent studies impede reliable identification of the nature and form of atypical alterations in grey-matter structural morphometry and intrinsic functional networks in ASD. This review aims to illustrate the heterogeneity in ASD neuroimaging literature by comparing systematic reviews and meta-analyses of neuroimaging investigations in ASD over the last several decades, with particular emphasis on structural morphometry, structural connectivity and resting-state intrinsic connectivity techniques. Given the unique challenges in ASD research, standardized methodologies to validate potential neuroimaging markers will be an important step towards advancing clinical and research methods to investigate complex aetiological mechanisms and risk factors underlying ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.11.005 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298

Brain activity during facial processing in autism spectrum disorder: an activation likelihood estimation (ALE) meta-analysis of neuroimaging studies / Cristiano COSTA in Journal of Child Psychology and Psychiatry, 62-12 (December 2021)  

Permalink

Brain morphology, autistic traits, and polygenic risk for autism: A population-based neuroimaging study / Silvia ALEMANY in Autism Research, 14-10 (October 2021)  

Permalink

Brief Report: Neuroimaging Endophenotypes of Social Robotic Applications in Autism Spectrum Disorder / Antonio CERASA in Journal of Autism and Developmental Disorders, 51-7 (July 2021)  

Permalink

Editorial: Neuroimaging in clinical psychiatry – when will the pay off begin? / Argyris STRINGARIS in Journal of Child Psychology and Psychiatry, 56-12 (December 2015)  

Permalink

Hemispheric differences in language processing in autism spectrum disorders: A meta-analysis of neuroimaging studies / Abbey J. HERRINGSHAW in Autism Research, 9-10 (October 2016)  

Permalink