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Détail de l'auteur
Auteur T. THOMPSON |
Documents disponibles écrits par cet auteur (2)
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Association between autism spectrum disorder and inflammatory bowel disease: A systematic review and meta-analysis / J. Y. KIM in Autism Research, 15-2 (February 2022)
[article]
Titre : Association between autism spectrum disorder and inflammatory bowel disease: A systematic review and meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : J. Y. KIM, Auteur ; M. J. CHOI, Auteur ; S. HA, Auteur ; J. HWANG, Auteur ; A. KOYANAGI, Auteur ; E. DRAGIOTI, Auteur ; J. RADUA, Auteur ; L. SMITH, Auteur ; L. JACOB, Auteur ; G. S. DE PABLO, Auteur ; S. W. LEE, Auteur ; D. K. YON, Auteur ; T. THOMPSON, Auteur ; S. CORTESE, Auteur ; G. LOLLO, Auteur ; C. S. LIANG, Auteur ; C. S. CHU, Auteur ; P. FUSAR-POLI, Auteur ; Keun-Ah CHEON, Auteur ; J. I. SHIN, Auteur ; M. SOLMI, Auteur Article en page(s) : p.340-352 Langues : Anglais (eng) Mots-clés : Crohn's disease autism spectrum disorder inflammatory bowel disease meta-analysis ulcerative colitis Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) are frequently diagnosed with co-occurring medical conditions including inflammatory bowel disease (IBD). To investigate the association, we conducted a systematic review registered in PROSPERO (ID:CRD42021236263) with a random-effects meta-analysis. We searched PubMed, Embase, and PsycInfo (last search on January 25, 2021), and manually searched relevant publications. We included observational studies measuring the association between ASD and IBD. The primary outcome was the association (odds ratio, OR) between ASD and later development of IBD. Sensitivity analyses were conducted by quality, confounding adjustment, and study design. We performed meta-regression analyses and assessed heterogeneity, publication bias, and quality of studies with the Newcastle-Ottawa Scale. Overall, we included six studies consisting of eight datasets, including over 11 million participants. We found that ASD was significantly associated with subsequent incident IBD (any IBD, OR = 1.66, 95% confidence interval[CI] = 1.25-2.21, p 0.001; ulcerative colitis, OR = 1.91, 95%CI = 1.41-2.6, p 0.001; Crohn's disease, OR = 1.47, 95%CI = 1.15-1.88, p?= 0.002). ASD and IBD were also associated regardless of temporal sequence of diagnosis (any IBD, OR = 1.57, 95%CI = 1.28-1.93, p 0.001; ulcerative colitis, OR = 1.7, 95%CI = 1.36-2.12, p 0.001; Crohn's disease, OR = 1.37, 95%CI = 1.12-1.69, p?= 0.003). Sensitivity analyses confirmed the findings of the main analysis. Meta-regression did not identify any significant moderators. Publication bias was not detected. Quality was high in four datasets and medium in four. In conclusion, our findings highlight the need to screen for IBD in individuals with ASD, and future research should identify who, among those with ASD, has the highest risk of IBD, and elucidate the shared biological mechanisms between ASD and IBD. LAY SUMMARY: This systematic review and meta-analysis of eight observational datasets found that individuals with autism spectrum disorder (ASD) are more likely to develop any inflammatory bowel disease, ulcerative colitis, or Crohn's disease. Our findings highlight the need to screen for inflammatory bowel disease in patients with ASD and elucidate the shared biological mechanisms between the two disorders. En ligne : http://dx.doi.org/10.1002/aur.2656 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450
in Autism Research > 15-2 (February 2022) . - p.340-352[article] Association between autism spectrum disorder and inflammatory bowel disease: A systematic review and meta-analysis [Texte imprimé et/ou numérique] / J. Y. KIM, Auteur ; M. J. CHOI, Auteur ; S. HA, Auteur ; J. HWANG, Auteur ; A. KOYANAGI, Auteur ; E. DRAGIOTI, Auteur ; J. RADUA, Auteur ; L. SMITH, Auteur ; L. JACOB, Auteur ; G. S. DE PABLO, Auteur ; S. W. LEE, Auteur ; D. K. YON, Auteur ; T. THOMPSON, Auteur ; S. CORTESE, Auteur ; G. LOLLO, Auteur ; C. S. LIANG, Auteur ; C. S. CHU, Auteur ; P. FUSAR-POLI, Auteur ; Keun-Ah CHEON, Auteur ; J. I. SHIN, Auteur ; M. SOLMI, Auteur . - p.340-352.
Langues : Anglais (eng)
in Autism Research > 15-2 (February 2022) . - p.340-352
Mots-clés : Crohn's disease autism spectrum disorder inflammatory bowel disease meta-analysis ulcerative colitis Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) are frequently diagnosed with co-occurring medical conditions including inflammatory bowel disease (IBD). To investigate the association, we conducted a systematic review registered in PROSPERO (ID:CRD42021236263) with a random-effects meta-analysis. We searched PubMed, Embase, and PsycInfo (last search on January 25, 2021), and manually searched relevant publications. We included observational studies measuring the association between ASD and IBD. The primary outcome was the association (odds ratio, OR) between ASD and later development of IBD. Sensitivity analyses were conducted by quality, confounding adjustment, and study design. We performed meta-regression analyses and assessed heterogeneity, publication bias, and quality of studies with the Newcastle-Ottawa Scale. Overall, we included six studies consisting of eight datasets, including over 11 million participants. We found that ASD was significantly associated with subsequent incident IBD (any IBD, OR = 1.66, 95% confidence interval[CI] = 1.25-2.21, p 0.001; ulcerative colitis, OR = 1.91, 95%CI = 1.41-2.6, p 0.001; Crohn's disease, OR = 1.47, 95%CI = 1.15-1.88, p?= 0.002). ASD and IBD were also associated regardless of temporal sequence of diagnosis (any IBD, OR = 1.57, 95%CI = 1.28-1.93, p 0.001; ulcerative colitis, OR = 1.7, 95%CI = 1.36-2.12, p 0.001; Crohn's disease, OR = 1.37, 95%CI = 1.12-1.69, p?= 0.003). Sensitivity analyses confirmed the findings of the main analysis. Meta-regression did not identify any significant moderators. Publication bias was not detected. Quality was high in four datasets and medium in four. In conclusion, our findings highlight the need to screen for IBD in individuals with ASD, and future research should identify who, among those with ASD, has the highest risk of IBD, and elucidate the shared biological mechanisms between ASD and IBD. LAY SUMMARY: This systematic review and meta-analysis of eight observational datasets found that individuals with autism spectrum disorder (ASD) are more likely to develop any inflammatory bowel disease, ulcerative colitis, or Crohn's disease. Our findings highlight the need to screen for inflammatory bowel disease in patients with ASD and elucidate the shared biological mechanisms between the two disorders. En ligne : http://dx.doi.org/10.1002/aur.2656 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 Brief Report: Feasibility and Preliminary Efficacy of a Behavioral Intervention for Minimally Verbal Girls with Autism Spectrum Disorder / T. CARIVEAU in Journal of Autism and Developmental Disorders, 49-5 (May 2019)
[article]
Titre : Brief Report: Feasibility and Preliminary Efficacy of a Behavioral Intervention for Minimally Verbal Girls with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : T. CARIVEAU, Auteur ; M. A. SHILLINGSBURG, Auteur ; A. ALAMOUDI, Auteur ; T. THOMPSON, Auteur ; B. BARTLETT, Auteur ; S. GILLESPIE, Auteur ; Lawrence SCAHILL, Auteur Article en page(s) : p.2203-2209 Langues : Anglais (eng) Mots-clés : Feasibility Female Intervention Minimally verbal Sex differences Index. décimale : PER Périodiques Résumé : We report the feasibility and preliminary efficacy of a structured behavioral intervention with a sample of minimally verbal girls with autism spectrum disorder between the ages of 2 and 6 years old. Ten participants with no functional vocal behavior were randomized to a 4-week behavioral intervention or waitlist control group. Caregivers reported child communicative repertoires at pre- and post-randomization assessments. Social communication was also assessed at these time points using the Early Social Communication Scales. All feasibility benchmarks were met and findings of preliminary efficacy showed large effect sizes within groups. The current findings suggest the feasibility of recruiting and retaining samples of young, minimally verbal girls with autism spectrum disorder in randomized clinical trials. En ligne : http://dx.doi.org/10.1007/s10803-018-03872-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=393
in Journal of Autism and Developmental Disorders > 49-5 (May 2019) . - p.2203-2209[article] Brief Report: Feasibility and Preliminary Efficacy of a Behavioral Intervention for Minimally Verbal Girls with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / T. CARIVEAU, Auteur ; M. A. SHILLINGSBURG, Auteur ; A. ALAMOUDI, Auteur ; T. THOMPSON, Auteur ; B. BARTLETT, Auteur ; S. GILLESPIE, Auteur ; Lawrence SCAHILL, Auteur . - p.2203-2209.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 49-5 (May 2019) . - p.2203-2209
Mots-clés : Feasibility Female Intervention Minimally verbal Sex differences Index. décimale : PER Périodiques Résumé : We report the feasibility and preliminary efficacy of a structured behavioral intervention with a sample of minimally verbal girls with autism spectrum disorder between the ages of 2 and 6 years old. Ten participants with no functional vocal behavior were randomized to a 4-week behavioral intervention or waitlist control group. Caregivers reported child communicative repertoires at pre- and post-randomization assessments. Social communication was also assessed at these time points using the Early Social Communication Scales. All feasibility benchmarks were met and findings of preliminary efficacy showed large effect sizes within groups. The current findings suggest the feasibility of recruiting and retaining samples of young, minimally verbal girls with autism spectrum disorder in randomized clinical trials. En ligne : http://dx.doi.org/10.1007/s10803-018-03872-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=393