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Détail de l'auteur
Auteur Lauren K. BRYANT |
Documents disponibles écrits par cet auteur (2)
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Neural Correlates of Cardiac Interoceptive Focus Across Development: Implications for Social Symptoms in Autism Spectrum Disorder / Michelle D. FAILLA in Autism Research, 13-6 (June 2020)
[article]
Titre : Neural Correlates of Cardiac Interoceptive Focus Across Development: Implications for Social Symptoms in Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Michelle D. FAILLA, Auteur ; Lauren K. BRYANT, Auteur ; Brynna H. HEFLIN, Auteur ; Lisa E. MASH, Auteur ; Kimberly B. SCHAUDER, Auteur ; Samona DAVIS, Auteur ; Madison B. GERDES, Auteur ; Amy WEITLAUF, Auteur ; Baxter P. ROGERS, Auteur ; Carissa J. CASCIO, Auteur Article en page(s) : p.908-920 Langues : Anglais (eng) Mots-clés : autism development fMRI insula interoception Index. décimale : PER Périodiques Résumé : Interoception involves the processing of sensory information relevant to physiological functioning and is integral to building self-awareness, emotional states, and modulating social behaviors. With the role of interoception in emotional processing and social functioning, there is growing interest in characterizing interoception in autism spectrum disorder (ASD), yet, there are mixed results regarding cardiac interoceptive accuracy in ASD. In this study, we explored the neural basis of cardiac interoception using an fMRI heartbeat-counting task in order to assess neural correlates of primary interoception. We predicted that interoceptive-specific response in the insula, a "hub" for interoception, would be related to ASD symptomatology. We investigated the relationship of insula responses during cardiac interoceptive focus and a self/caregiver-reported autism-related symptom scale (Social Responsiveness Scale-2 (SRS)). Participants included 46 individuals with autism spectrum disorder (ASD) (age 8-54, mean = 19.43?±?10.68?years) and 54 individuals with typical development for comparison (TC, age 8-53, mean = 21.43?±?10.41?years). We found no significant difference in cardiac interoceptive accuracy or neural response to cardiac interoception focus in ASD. Several insula subdivisions had a curvilinear relationship to age, peaking in early adulthood. Interoceptive-specific insula response was associated with adult self-report SRS scores; this association differed by diagnostic group and was not present for caregiver-reported scores. This work suggests that (a) there is no global deficit in cardiac interoception in ASD, but integrating interoceptive cues with social information may distinguish individuals with ASD, and (b) there is a developmental trajectory for interoceptive processing in the insula that may be relevant for socio-emotional health. Autism Res 2020, 13: 908-920. © 2020 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: We use internal sensory information from the body, such as signals from the heart, to understand our emotional response to the external world. We measured how accurately people with autism feel their heartbeat and how the brain responds to this type of information. We found no differences between the autism and comparison groups in how the brain senses heartbeats, or in how accurately people feel their heartbeats. However, for people with autism, brain responses while sensing heartbeats were related to social difficulties. This work suggests people with autism may use internal and external information in a different way. En ligne : http://dx.doi.org/10.1002/aur.2289 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=427
in Autism Research > 13-6 (June 2020) . - p.908-920[article] Neural Correlates of Cardiac Interoceptive Focus Across Development: Implications for Social Symptoms in Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Michelle D. FAILLA, Auteur ; Lauren K. BRYANT, Auteur ; Brynna H. HEFLIN, Auteur ; Lisa E. MASH, Auteur ; Kimberly B. SCHAUDER, Auteur ; Samona DAVIS, Auteur ; Madison B. GERDES, Auteur ; Amy WEITLAUF, Auteur ; Baxter P. ROGERS, Auteur ; Carissa J. CASCIO, Auteur . - p.908-920.
Langues : Anglais (eng)
in Autism Research > 13-6 (June 2020) . - p.908-920
Mots-clés : autism development fMRI insula interoception Index. décimale : PER Périodiques Résumé : Interoception involves the processing of sensory information relevant to physiological functioning and is integral to building self-awareness, emotional states, and modulating social behaviors. With the role of interoception in emotional processing and social functioning, there is growing interest in characterizing interoception in autism spectrum disorder (ASD), yet, there are mixed results regarding cardiac interoceptive accuracy in ASD. In this study, we explored the neural basis of cardiac interoception using an fMRI heartbeat-counting task in order to assess neural correlates of primary interoception. We predicted that interoceptive-specific response in the insula, a "hub" for interoception, would be related to ASD symptomatology. We investigated the relationship of insula responses during cardiac interoceptive focus and a self/caregiver-reported autism-related symptom scale (Social Responsiveness Scale-2 (SRS)). Participants included 46 individuals with autism spectrum disorder (ASD) (age 8-54, mean = 19.43?±?10.68?years) and 54 individuals with typical development for comparison (TC, age 8-53, mean = 21.43?±?10.41?years). We found no significant difference in cardiac interoceptive accuracy or neural response to cardiac interoception focus in ASD. Several insula subdivisions had a curvilinear relationship to age, peaking in early adulthood. Interoceptive-specific insula response was associated with adult self-report SRS scores; this association differed by diagnostic group and was not present for caregiver-reported scores. This work suggests that (a) there is no global deficit in cardiac interoception in ASD, but integrating interoceptive cues with social information may distinguish individuals with ASD, and (b) there is a developmental trajectory for interoceptive processing in the insula that may be relevant for socio-emotional health. Autism Res 2020, 13: 908-920. © 2020 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: We use internal sensory information from the body, such as signals from the heart, to understand our emotional response to the external world. We measured how accurately people with autism feel their heartbeat and how the brain responds to this type of information. We found no differences between the autism and comparison groups in how the brain senses heartbeats, or in how accurately people feel their heartbeats. However, for people with autism, brain responses while sensing heartbeats were related to social difficulties. This work suggests people with autism may use internal and external information in a different way. En ligne : http://dx.doi.org/10.1002/aur.2289 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=427 Self-reported Sensory Hypersensitivity Moderates Association Between Tactile Psychophysical Performance and Autism-Related Traits in Neurotypical Adults / Lauren K. BRYANT in Journal of Autism and Developmental Disorders, 49-8 (August 2019)
[article]
Titre : Self-reported Sensory Hypersensitivity Moderates Association Between Tactile Psychophysical Performance and Autism-Related Traits in Neurotypical Adults Type de document : Texte imprimé et/ou numérique Auteurs : Lauren K. BRYANT, Auteur ; Tiffany G. WOYNAROSKI, Auteur ; Mark T. WALLACE, Auteur ; Carissa J. CASCIO, Auteur Article en page(s) : p.3159-3172 Langues : Anglais (eng) Mots-clés : Autism Broader phenotype Dynamic range Psychophysics Somatosensory Tactile Index. décimale : PER Périodiques Résumé : Atypical responses to tactile stimulation have been linked to core domains of dysfunction in individuals with autism spectrum disorder (ASD) and phenotypic traits associated with ASD in neurotypical individuals. We investigated (a) the extent to which two psychophysically derived measures of tactile sensitivity-detection threshold and dynamic range-relate to traits associated with ASD and (b) whether those relations vary according to the presence of self-reported sensory hypersensitivities in neurotypical individuals. A narrow dynamic range was associated with increased autism-related traits in individuals who reported greater sensory hypersensitivity. In contrast, in individuals less prone to sensory hypersensitivity, a narrow dynamic range was associated with reduced autism-related traits. Findings highlight the potential importance of considering dynamic psychophysical metrics in future studies. En ligne : http://dx.doi.org/10.1007/s10803-019-04043-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=403
in Journal of Autism and Developmental Disorders > 49-8 (August 2019) . - p.3159-3172[article] Self-reported Sensory Hypersensitivity Moderates Association Between Tactile Psychophysical Performance and Autism-Related Traits in Neurotypical Adults [Texte imprimé et/ou numérique] / Lauren K. BRYANT, Auteur ; Tiffany G. WOYNAROSKI, Auteur ; Mark T. WALLACE, Auteur ; Carissa J. CASCIO, Auteur . - p.3159-3172.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 49-8 (August 2019) . - p.3159-3172
Mots-clés : Autism Broader phenotype Dynamic range Psychophysics Somatosensory Tactile Index. décimale : PER Périodiques Résumé : Atypical responses to tactile stimulation have been linked to core domains of dysfunction in individuals with autism spectrum disorder (ASD) and phenotypic traits associated with ASD in neurotypical individuals. We investigated (a) the extent to which two psychophysically derived measures of tactile sensitivity-detection threshold and dynamic range-relate to traits associated with ASD and (b) whether those relations vary according to the presence of self-reported sensory hypersensitivities in neurotypical individuals. A narrow dynamic range was associated with increased autism-related traits in individuals who reported greater sensory hypersensitivity. In contrast, in individuals less prone to sensory hypersensitivity, a narrow dynamic range was associated with reduced autism-related traits. Findings highlight the potential importance of considering dynamic psychophysical metrics in future studies. En ligne : http://dx.doi.org/10.1007/s10803-019-04043-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=403