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EEG Abnormalities as a Neurophysiological Biomarker of Severity in Autism Spectrum Disorder: A Pilot Cohort Study / Antonio Gennaro NICOTERA in Journal of Autism and Developmental Disorders, 49-6 (June 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-6 (June 2019) . - p.2337-2347 Titre : EEG Abnormalities as a Neurophysiological Biomarker of Severity in Autism Spectrum Disorder: A Pilot Cohort Study Type de document : texte imprimé Auteurs : Antonio Gennaro NICOTERA, Auteur ; Randi J. HAGERMAN, Auteur ; Maria Vincenza CATANIA, Auteur ; Serafino BUONO, Auteur ; Santo DI NUOVO, Auteur ; Elisa Maria LIPRINO, Auteur ; Emanuela STRACUZZI, Auteur ; Stefania GIUSTO, Auteur ; Giuseppa DI VITA, Auteur ; Sebastiano Antonino MUSUMECI, Auteur Article en page(s) : p.2337-2347 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Biomarker  Epileptiform abnormalities  Hyperactivity  Phenotype Index. décimale : PER Périodiques Résumé : To date, the phenotypic significance of EEG abnormalities in patients with ASD is unclear. In a population affected by ASD we aimed to evaluate: the phenotypic characteristics; the prevalence of EEG abnormalities; the potential correlations between EEG abnormalities and behavioral and cognitive variables. Sixty-nine patients with ASD underwent cognitive or developmental testing, language assessment, and adaptive behavior skills evaluation as well as sleep/wake EEG recording. EEG abnormalities were found in 39.13% of patients. EEG abnormalities correlated with autism severity, hyperactivity, anger outbursts, aggression, negative or destructive behavior, motor stereotypies, intellectual disability, language impairment and self-harm. Our findings confirmed that EEG abnormalities are present in the ASD population and correlate with several associated phenotypic features. En ligne : https://dx.doi.org/10.1007/s10803-019-03908-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=400 [article] EEG Abnormalities as a Neurophysiological Biomarker of Severity in Autism Spectrum Disorder: A Pilot Cohort Study [texte imprimé] / Antonio Gennaro NICOTERA, Auteur ; Randi J. HAGERMAN, Auteur ; Maria Vincenza CATANIA, Auteur ; Serafino BUONO, Auteur ; Santo DI NUOVO, Auteur ; Elisa Maria LIPRINO, Auteur ; Emanuela STRACUZZI, Auteur ; Stefania GIUSTO, Auteur ; Giuseppa DI VITA, Auteur ; Sebastiano Antonino MUSUMECI, Auteur . - p.2337-2347. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-6 (June 2019) . - p.2337-2347 Mots-clés : Autism spectrum disorder  Biomarker  Epileptiform abnormalities  Hyperactivity  Phenotype Index. décimale : PER Périodiques Résumé : To date, the phenotypic significance of EEG abnormalities in patients with ASD is unclear. In a population affected by ASD we aimed to evaluate: the phenotypic characteristics; the prevalence of EEG abnormalities; the potential correlations between EEG abnormalities and behavioral and cognitive variables. Sixty-nine patients with ASD underwent cognitive or developmental testing, language assessment, and adaptive behavior skills evaluation as well as sleep/wake EEG recording. EEG abnormalities were found in 39.13% of patients. EEG abnormalities correlated with autism severity, hyperactivity, anger outbursts, aggression, negative or destructive behavior, motor stereotypies, intellectual disability, language impairment and self-harm. Our findings confirmed that EEG abnormalities are present in the ASD population and correlate with several associated phenotypic features. En ligne : https://dx.doi.org/10.1007/s10803-019-03908-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=400