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A transdiagnostic model of psychiatric symptom co-occurrence and autism spectrum disorder / Craig RODRIGUEZ-SEIJAS in Autism Research, 13-4 (April 2020)
[article]
Titre : A transdiagnostic model of psychiatric symptom co-occurrence and autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Craig RODRIGUEZ-SEIJAS, Auteur ; Kenneth D GADOW, Auteur ; Tamara E. ROSEN, Auteur ; Hyunsik KIM, Auteur ; Matthew D LERNER, Auteur ; Nicholas R. EATON, Auteur Article en page(s) : p.579-590 Langues : Anglais (eng) Mots-clés : autism spectrum disorder comorbidity factorial invariance transdiagnostic factors Index. décimale : PER Périodiques Résumé : Understanding whether the co-occurrence of psychiatric symptoms within autism spectrum disorder (ASD) are specific to the ASD diagnosis or reflect similar higher-order patterns observed in both ASD and non-ASD samples, or a confluence of the two, is of critical importance. If similar, it would suggest that comorbid psychiatric conditions among individuals with ASD are not symptoms of specific, non-ASD psychiatric disorders per se, but reflect a general liability to psychopathology associated with ASD. To this end, the current study examined whether the higher-order structure of co-occurring psychiatric symptoms was the same within ASD and non-ASD youth. Parents of clinic-referred youth with (n = 280) and without (n = 943) ASD completed a DSM-IV-referenced psychiatric symptom rating scale. A confirmatory factor analytic framework was used to examine four levels of measurement invariance across groups to determine the extent to which transdiagnostic factors were comparable. Transdiagnostic factors were characterized by symptoms of the same disorders (configural invariance) and the same factor loadings across groups (metric invariance). Furthermore, both groups evidenced equivalent numbers of symptoms of most psychiatric conditions with the notable exceptions of attention deficit hyperactivity disorder (ADHD) and social anxiety (partial strong invariance), which were higher in the ASD sample. It was concluded that disparities in the co-occurrence of psychiatric symptoms between youth with and without ASD may be largely reflective of transdiagnostic factor level differences associated with ASD and not indicative of the ASD diagnosis per se. However, for ADHD and social anxiety, there appears to be some specific associations with the ASD diagnosis. Autism Res 2020, 13: 579-590. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Few transdiagnostic dimensions relate common mental disorder diagnoses with one another. These dimensions explain psychiatric comorbidity (i.e., the finding that many persons possess several disorder diagnoses simultaneously). However, it is unclear if these dimensions differ among children with autism spectrum disorder (ASD), compared with their non-ASD counterparts. The results of this study demonstrate that underlying transdiagnostic dimensions are similar in both ASD and non-ASD children. However, there appear to be ASD-specific differences when it comes to social anxiety and attention deficit hyperactivity disorder. En ligne : http://dx.doi.org/10.1002/aur.2228 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=421
in Autism Research > 13-4 (April 2020) . - p.579-590[article] A transdiagnostic model of psychiatric symptom co-occurrence and autism spectrum disorder [Texte imprimé et/ou numérique] / Craig RODRIGUEZ-SEIJAS, Auteur ; Kenneth D GADOW, Auteur ; Tamara E. ROSEN, Auteur ; Hyunsik KIM, Auteur ; Matthew D LERNER, Auteur ; Nicholas R. EATON, Auteur . - p.579-590.
Langues : Anglais (eng)
in Autism Research > 13-4 (April 2020) . - p.579-590
Mots-clés : autism spectrum disorder comorbidity factorial invariance transdiagnostic factors Index. décimale : PER Périodiques Résumé : Understanding whether the co-occurrence of psychiatric symptoms within autism spectrum disorder (ASD) are specific to the ASD diagnosis or reflect similar higher-order patterns observed in both ASD and non-ASD samples, or a confluence of the two, is of critical importance. If similar, it would suggest that comorbid psychiatric conditions among individuals with ASD are not symptoms of specific, non-ASD psychiatric disorders per se, but reflect a general liability to psychopathology associated with ASD. To this end, the current study examined whether the higher-order structure of co-occurring psychiatric symptoms was the same within ASD and non-ASD youth. Parents of clinic-referred youth with (n = 280) and without (n = 943) ASD completed a DSM-IV-referenced psychiatric symptom rating scale. A confirmatory factor analytic framework was used to examine four levels of measurement invariance across groups to determine the extent to which transdiagnostic factors were comparable. Transdiagnostic factors were characterized by symptoms of the same disorders (configural invariance) and the same factor loadings across groups (metric invariance). Furthermore, both groups evidenced equivalent numbers of symptoms of most psychiatric conditions with the notable exceptions of attention deficit hyperactivity disorder (ADHD) and social anxiety (partial strong invariance), which were higher in the ASD sample. It was concluded that disparities in the co-occurrence of psychiatric symptoms between youth with and without ASD may be largely reflective of transdiagnostic factor level differences associated with ASD and not indicative of the ASD diagnosis per se. However, for ADHD and social anxiety, there appears to be some specific associations with the ASD diagnosis. Autism Res 2020, 13: 579-590. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Few transdiagnostic dimensions relate common mental disorder diagnoses with one another. These dimensions explain psychiatric comorbidity (i.e., the finding that many persons possess several disorder diagnoses simultaneously). However, it is unclear if these dimensions differ among children with autism spectrum disorder (ASD), compared with their non-ASD counterparts. The results of this study demonstrate that underlying transdiagnostic dimensions are similar in both ASD and non-ASD children. However, there appear to be ASD-specific differences when it comes to social anxiety and attention deficit hyperactivity disorder. En ligne : http://dx.doi.org/10.1002/aur.2228 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=421 Intolerance-of-uncertainty and anxiety as serial mediators between emotional dysregulation and repetitive patterns in young people with autism / Carmen BENEYTEZ in Research in Autism Spectrum Disorders, 102 (April 2023)
[article]
Titre : Intolerance-of-uncertainty and anxiety as serial mediators between emotional dysregulation and repetitive patterns in young people with autism Type de document : Texte imprimé et/ou numérique Auteurs : Carmen BENEYTEZ, Auteur Article en page(s) : p.102116 Langues : Anglais (eng) Mots-clés : Anxiety Transdiagnostic factors Repetitive and restricted patterns Emotional well-being Emotional dysregulation Uncertainty Index. décimale : PER Périodiques Résumé : Background Previous research on anxiety in autism has largely focused on direct relationships. The overlap between symptoms of autism and anxiety and the influence that transdiagnostic variables exert on them make necessary explanatory models that consider all the factors involved in the triggering and maintenance of anxiety and its expression through typical features of autism. Method The main objective of this study was to examine the relationship between two transdiagnostic mechanisms (emotional dysregulation (ED) and intolerance of uncertainty (IU)) and repetitive and restricted patterns (RRP) and the role that anxiety has in this relationship. IU and anxiety were configured as serial mediators between ED and two subtypes of restricted patterns: sameness behaviors and sensory over-responsiveness. The sample included 87 children and adolescents on the autism spectrum aged from 6 to 18 years. Variables were assessed using a number of well-known outcome measures. Results The results of our simple mediation model show that the indirect effect of anxiety is higher between transdiagnostic variables and sensory over-responsiveness than between transdiagnostic variables and sameness behaviors. Our model suggests that ED predicts sameness behaviors and sensory over-responsiveness through the serial indirect effect of IU and anxiety. Conclusions Our findings contribute to clarify the role that anxiety and transdiagnostic mechanisms may play on RRP and may have important implications for the assessment and treatment of anxiety in people with ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102116 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501
in Research in Autism Spectrum Disorders > 102 (April 2023) . - p.102116[article] Intolerance-of-uncertainty and anxiety as serial mediators between emotional dysregulation and repetitive patterns in young people with autism [Texte imprimé et/ou numérique] / Carmen BENEYTEZ, Auteur . - p.102116.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 102 (April 2023) . - p.102116
Mots-clés : Anxiety Transdiagnostic factors Repetitive and restricted patterns Emotional well-being Emotional dysregulation Uncertainty Index. décimale : PER Périodiques Résumé : Background Previous research on anxiety in autism has largely focused on direct relationships. The overlap between symptoms of autism and anxiety and the influence that transdiagnostic variables exert on them make necessary explanatory models that consider all the factors involved in the triggering and maintenance of anxiety and its expression through typical features of autism. Method The main objective of this study was to examine the relationship between two transdiagnostic mechanisms (emotional dysregulation (ED) and intolerance of uncertainty (IU)) and repetitive and restricted patterns (RRP) and the role that anxiety has in this relationship. IU and anxiety were configured as serial mediators between ED and two subtypes of restricted patterns: sameness behaviors and sensory over-responsiveness. The sample included 87 children and adolescents on the autism spectrum aged from 6 to 18 years. Variables were assessed using a number of well-known outcome measures. Results The results of our simple mediation model show that the indirect effect of anxiety is higher between transdiagnostic variables and sensory over-responsiveness than between transdiagnostic variables and sameness behaviors. Our model suggests that ED predicts sameness behaviors and sensory over-responsiveness through the serial indirect effect of IU and anxiety. Conclusions Our findings contribute to clarify the role that anxiety and transdiagnostic mechanisms may play on RRP and may have important implications for the assessment and treatment of anxiety in people with ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102116 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501