Abnormal Brain Dynamics Underlie Speech Production in Children with Autism Spectrum Disorder / Elizabeth W. PANG in Autism Research, 9-2 (February 2016)  

Public ISBD [article]  inAutism Research > 9-2 (February 2016) . - p.249-261 Titre : Abnormal Brain Dynamics Underlie Speech Production in Children with Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Elizabeth W. PANG, Auteur ; Tatiana VALICA, Auteur ; Matt J. MACDONALD, Auteur ; Margot J. TAYLOR, Auteur ; Jessica BRIAN, Auteur ; Jason P. LERCH, Auteur ; Evdokia ANAGNOSTOU, Auteur Article en page(s) : p.249-261 Langues : Anglais (eng) Mots-clés : magnetoencephalography  oromotor control  phoneme production  phonemic sequencing  autism spectrum disorder Index. décimale : PER Périodiques Résumé : A large proportion of children with autism spectrum disorder (ASD) have speech and/or language difficulties. While a number of structural and functional neuroimaging methods have been used to explore the brain differences in ASD with regards to speech and language comprehension and production, the neurobiology of basic speech function in ASD has not been examined. Magnetoencephalography (MEG) is a neuroimaging modality with high spatial and temporal resolution that can be applied to the examination of brain dynamics underlying speech as it can capture the fast responses fundamental to this function. We acquired MEG from 21 children with high-functioning autism (mean age: 11.43 years) and 21 age- and sex-matched controls as they performed a simple oromotor task, a phoneme production task and a phonemic sequencing task. Results showed significant differences in activation magnitude and peak latencies in primary motor cortex (Brodmann Area 4), motor planning areas (BA 6), temporal sequencing and sensorimotor integration areas (BA 22/13) and executive control areas (BA 9). Our findings of significant functional brain differences between these two groups on these simple oromotor and phonemic tasks suggest that these deficits may be foundational and could underlie the language deficits seen in ASD. En ligne : http://dx.doi.org/10.1002/aur.1526 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=282 [article] Abnormal Brain Dynamics Underlie Speech Production in Children with Autism Spectrum Disorder [texte imprimé] / Elizabeth W. PANG, Auteur ; Tatiana VALICA, Auteur ; Matt J. MACDONALD, Auteur ; Margot J. TAYLOR, Auteur ; Jessica BRIAN, Auteur ; Jason P. LERCH, Auteur ; Evdokia ANAGNOSTOU, Auteur . - p.249-261. Langues : Anglais (eng) in Autism Research > 9-2 (February 2016) . - p.249-261 Mots-clés : magnetoencephalography  oromotor control  phoneme production  phonemic sequencing  autism spectrum disorder Index. décimale : PER Périodiques Résumé : A large proportion of children with autism spectrum disorder (ASD) have speech and/or language difficulties. While a number of structural and functional neuroimaging methods have been used to explore the brain differences in ASD with regards to speech and language comprehension and production, the neurobiology of basic speech function in ASD has not been examined. Magnetoencephalography (MEG) is a neuroimaging modality with high spatial and temporal resolution that can be applied to the examination of brain dynamics underlying speech as it can capture the fast responses fundamental to this function. We acquired MEG from 21 children with high-functioning autism (mean age: 11.43 years) and 21 age- and sex-matched controls as they performed a simple oromotor task, a phoneme production task and a phonemic sequencing task. Results showed significant differences in activation magnitude and peak latencies in primary motor cortex (Brodmann Area 4), motor planning areas (BA 6), temporal sequencing and sensorimotor integration areas (BA 22/13) and executive control areas (BA 9). Our findings of significant functional brain differences between these two groups on these simple oromotor and phonemic tasks suggest that these deficits may be foundational and could underlie the language deficits seen in ASD. En ligne : http://dx.doi.org/10.1002/aur.1526 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=282

Affect and gaze responses during an Emotion-Evoking Task in infants at an increased likelihood for autism spectrum disorder / Lori-Ann R. SACREY in Molecular Autism, 12 (2021)  

Public ISBD [article]  inMolecular Autism > 12 (2021) . - 63 p. Titre : Affect and gaze responses during an Emotion-Evoking Task in infants at an increased likelihood for autism spectrum disorder Type de document : texte imprimé Auteurs : Lori-Ann R. SACREY, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Jessica BRIAN, Auteur ; Isabel M. SMITH, Auteur ; V. ARMSTRONG, Auteur ; S. RAZA, Auteur ; Tracy VAILLANCOURT, Auteur ; Louis A. SCHMIDT, Auteur Article en page(s) : 63 p. Langues : Anglais (eng) Mots-clés : Affect  Autism  Emotion regulation  Gaze  Increased likelihood cohort  Temperament Index. décimale : PER Périodiques Résumé : BACKGROUND: The majority of research examining emotional difficulties in autism spectrum disorder (ASD) prior to age 2 relies on parent report. METHODS: We examined behavioral responses (affect and gaze) during emotionally salient tasks designed to elicit mildly positive and negative emotional states in infants. At 12 and 18 months, infants at an increased likelihood for an ASD diagnosis (IL; have an older sibling with ASD; n = 60) and low likelihood (LL; no family history of ASD; n = 21) completed the Emotion-Evoking (EE) Task and parents completed the Infant Behavior Questionnaire-Revised (IBQ-R). All children received an Autism Diagnostic Observation Scale-second Edition assessment for ASD symptomatology at 24 months. RESULTS: The main findings were (1) the IL group displayed higher rates of negative affect and spent less time looking at the task objects compared to the LL group, and (2) affect and gaze scores at 12 and 18 months, but not scores on the IBQ-R, predicted ASD symptoms at 24 months. LIMITATIONS: The data were drawn from an IL sample and may not be generalizable to the general ASD population, and the children were not followed to determine a diagnosis of ASD. CONCLUSION: These results suggest that behavioral responses can provide important information that complements parent reports of emotional regulation in IL infants as early as 12 months of age. En ligne : http://dx.doi.org/10.1186/s13229-021-00468-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=459 [article] Affect and gaze responses during an Emotion-Evoking Task in infants at an increased likelihood for autism spectrum disorder [texte imprimé] / Lori-Ann R. SACREY, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Jessica BRIAN, Auteur ; Isabel M. SMITH, Auteur ; V. ARMSTRONG, Auteur ; S. RAZA, Auteur ; Tracy VAILLANCOURT, Auteur ; Louis A. SCHMIDT, Auteur . - 63 p. Langues : Anglais (eng) in Molecular Autism > 12 (2021) . - 63 p. Mots-clés : Affect  Autism  Emotion regulation  Gaze  Increased likelihood cohort  Temperament Index. décimale : PER Périodiques Résumé : BACKGROUND: The majority of research examining emotional difficulties in autism spectrum disorder (ASD) prior to age 2 relies on parent report. METHODS: We examined behavioral responses (affect and gaze) during emotionally salient tasks designed to elicit mildly positive and negative emotional states in infants. At 12 and 18 months, infants at an increased likelihood for an ASD diagnosis (IL; have an older sibling with ASD; n = 60) and low likelihood (LL; no family history of ASD; n = 21) completed the Emotion-Evoking (EE) Task and parents completed the Infant Behavior Questionnaire-Revised (IBQ-R). All children received an Autism Diagnostic Observation Scale-second Edition assessment for ASD symptomatology at 24 months. RESULTS: The main findings were (1) the IL group displayed higher rates of negative affect and spent less time looking at the task objects compared to the LL group, and (2) affect and gaze scores at 12 and 18 months, but not scores on the IBQ-R, predicted ASD symptoms at 24 months. LIMITATIONS: The data were drawn from an IL sample and may not be generalizable to the general ASD population, and the children were not followed to determine a diagnosis of ASD. CONCLUSION: These results suggest that behavioral responses can provide important information that complements parent reports of emotional regulation in IL infants as early as 12 months of age. En ligne : http://dx.doi.org/10.1186/s13229-021-00468-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=459

Atypical sympathetic arousal in children with autism spectrum disorder and its association with anxiety symptomatology / Sakeena PANJU in Molecular Autism, (December 2015)  

Public ISBD [article]  inMolecular Autism > (December 2015) . - p.1-10 Titre : Atypical sympathetic arousal in children with autism spectrum disorder and its association with anxiety symptomatology Type de document : texte imprimé Auteurs : Sakeena PANJU, Auteur ; Jessica BRIAN, Auteur ; Annie DUPUIS, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Azadeh KUSHKI, Auteur Article en page(s) : p.1-10 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) has been associated with autonomic atypicalities, although the nature of these differences remains largely unknown. Moreover, existing literature suggests large variability in autonomic function in ASD, motivating the need to examine the existence of subgroups that exhibit more homogeneous autonomic features. En ligne : http://dx.doi.org/10.1186/s13229-015-0057-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Atypical sympathetic arousal in children with autism spectrum disorder and its association with anxiety symptomatology [texte imprimé] / Sakeena PANJU, Auteur ; Jessica BRIAN, Auteur ; Annie DUPUIS, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Azadeh KUSHKI, Auteur . - p.1-10. Langues : Anglais (eng) in Molecular Autism > (December 2015) . - p.1-10 Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) has been associated with autonomic atypicalities, although the nature of these differences remains largely unknown. Moreover, existing literature suggests large variability in autonomic function in ASD, motivating the need to examine the existence of subgroups that exhibit more homogeneous autonomic features. En ligne : http://dx.doi.org/10.1186/s13229-015-0057-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

Behavioral and physiological differences during an emotion-evoking task in children at increased likelihood for autism spectrum disorder / Lori-Ann R. SACREY in Development and Psychopathology, 36-1 (February 2024)  

Public ISBD [article]  inDevelopment and Psychopathology > 36-1 (February 2024) . - p.404-414 Titre : Behavioral and physiological differences during an emotion-evoking task in children at increased likelihood for autism spectrum disorder Type de document : texte imprimé Auteurs : Lori-Ann R. SACREY, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Jessica BRIAN, Auteur ; Isabel M. SMITH, Auteur ; Vickie ARMSTRONG, Auteur ; Tracy VAILLANCOURT, Auteur ; Louis A. SCHMIDT, Auteur Article en page(s) : p.404-414 Langues : Anglais (eng) Mots-clés : ASD  affect  autism  baby sibling  gaze  heart rate  physiology Index. décimale : PER Périodiques Résumé : Literature examining emotional regulation in infants with autism spectrum disorder (ASD) has focused on parent report. We examined behavioral and physiological responses during an emotion-evoking task designed to elicit emotional states in infants. Infants at an increased likelihood for ASD (IL; have an older sibling with ASD; 96 not classified; 29 classified with ASD at age two) and low likelihood (LL; no family history of ASD; n = 61) completed the task at 6, 12, and 18 months. The main findings were (1) the IL-ASD group displayed higher levels of negative affect during toy removal and negative tasks compared to the IL non-ASD and LL groups, respectively, (2) the IL-ASD group spent more time looking at the baseline task compared to the other two groups, and (3) the IL-ASD group showed a greater increase in heart rate from baseline during the toy removal and negative tasks compared to the LL group. These results suggest that IL children who are classified as ASD at 24 months show differences in affect, gaze, and heart rate during an emotion-evoking task, with potential implications for understanding mechanisms related to emerging ASD. En ligne : https://dx.doi.org/10.1017/S0954579422001286 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523 [article] Behavioral and physiological differences during an emotion-evoking task in children at increased likelihood for autism spectrum disorder [texte imprimé] / Lori-Ann R. SACREY, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Jessica BRIAN, Auteur ; Isabel M. SMITH, Auteur ; Vickie ARMSTRONG, Auteur ; Tracy VAILLANCOURT, Auteur ; Louis A. SCHMIDT, Auteur . - p.404-414. Langues : Anglais (eng) in Development and Psychopathology > 36-1 (February 2024) . - p.404-414 Mots-clés : ASD  affect  autism  baby sibling  gaze  heart rate  physiology Index. décimale : PER Périodiques Résumé : Literature examining emotional regulation in infants with autism spectrum disorder (ASD) has focused on parent report. We examined behavioral and physiological responses during an emotion-evoking task designed to elicit emotional states in infants. Infants at an increased likelihood for ASD (IL; have an older sibling with ASD; 96 not classified; 29 classified with ASD at age two) and low likelihood (LL; no family history of ASD; n = 61) completed the task at 6, 12, and 18 months. The main findings were (1) the IL-ASD group displayed higher levels of negative affect during toy removal and negative tasks compared to the IL non-ASD and LL groups, respectively, (2) the IL-ASD group spent more time looking at the baseline task compared to the other two groups, and (3) the IL-ASD group showed a greater increase in heart rate from baseline during the toy removal and negative tasks compared to the LL group. These results suggest that IL children who are classified as ASD at 24 months show differences in affect, gaze, and heart rate during an emotion-evoking task, with potential implications for understanding mechanisms related to emerging ASD. En ligne : https://dx.doi.org/10.1017/S0954579422001286 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523

Brain and Language Associations in Autism Spectrum Disorder: A Scoping Review / Carly A. CERMAK in Journal of Autism and Developmental Disorders, 52-2 (February 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-2 (February 2022) . - p.725-737 Titre : Brain and Language Associations in Autism Spectrum Disorder: A Scoping Review Type de document : texte imprimé Auteurs : Carly A. CERMAK, Auteur ; S. ARSHINOFF, Auteur ; Leticia RIBEIRO DE OLIVEIRA, Auteur ; A. TENDERA, Auteur ; D.S. BEAL, Auteur ; Jessica BRIAN, Auteur ; Evdokia ANAGNOSTOU, Auteur ; T. SANJEEVAN, Auteur Article en page(s) : p.725-737 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnostic imaging  Brain/diagnostic imaging  Humans  Language  Neuroimaging  Autism spectrum disorder  Scoping review Index. décimale : PER Périodiques Résumé : Examining brain and behaviour associations for language in autism spectrum disorder (ASD) may bring us closer to identifying neural profiles that are unique to a subgroup of individuals with ASD identified as language impaired (e.g. ASD LI+). We conducted a scoping review to examine brain regions that are associated with language performance in ASD. Further, we examined methodological differences across studies in how language ability was characterized and what neuroimaging methods were used to explore brain regions. Seventeen studies met inclusion criteria. Brain regions specific to ASD LI+ groups were found, however inconsistencies in brain and language associations were evident across study findings. Participant age, age-appropriate language scores, and neuroimaging methods likely contributed to differences in associations found. En ligne : http://dx.doi.org/10.1007/s10803-021-04975-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455 [article] Brain and Language Associations in Autism Spectrum Disorder: A Scoping Review [texte imprimé] / Carly A. CERMAK, Auteur ; S. ARSHINOFF, Auteur ; Leticia RIBEIRO DE OLIVEIRA, Auteur ; A. TENDERA, Auteur ; D.S. BEAL, Auteur ; Jessica BRIAN, Auteur ; Evdokia ANAGNOSTOU, Auteur ; T. SANJEEVAN, Auteur . - p.725-737. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-2 (February 2022) . - p.725-737 Mots-clés : Autism Spectrum Disorder/diagnostic imaging  Brain/diagnostic imaging  Humans  Language  Neuroimaging  Autism spectrum disorder  Scoping review Index. décimale : PER Périodiques Résumé : Examining brain and behaviour associations for language in autism spectrum disorder (ASD) may bring us closer to identifying neural profiles that are unique to a subgroup of individuals with ASD identified as language impaired (e.g. ASD LI+). We conducted a scoping review to examine brain regions that are associated with language performance in ASD. Further, we examined methodological differences across studies in how language ability was characterized and what neuroimaging methods were used to explore brain regions. Seventeen studies met inclusion criteria. Brain regions specific to ASD LI+ groups were found, however inconsistencies in brain and language associations were evident across study findings. Participant age, age-appropriate language scores, and neuroimaging methods likely contributed to differences in associations found. En ligne : http://dx.doi.org/10.1007/s10803-021-04975-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455

Brief Report: Assessment of Early Sensory Processing in Infants at High-Risk of Autism Spectrum Disorder / Tamara GERMANI in Journal of Autism and Developmental Disorders, 44-12 (December 2014)  

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Brief Report: Characteristics of preschool children with ASD vary by ascertainment / Lori-Ann R. SACREY in Journal of Autism and Developmental Disorders, 47-5 (May 2017)  

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Brief Report: Evaluation of the Short Quantitative Checklist for Autism in Toddlers (Q-CHAT-10) as a Brief Screen for Autism Spectrum Disorder in a High-Risk Sibling Cohort / S. RAZA in Journal of Autism and Developmental Disorders, 49-5 (May 2019)  

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Brief Report: Preliminary Feasibility of the TEDI: A Novel Parent-Administered Telehealth Assessment for Autism Spectrum Disorder Symptoms in the First Year of Life / Meagan R. TALBOTT in Journal of Autism and Developmental Disorders, 50-9 (September 2020)  

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Clinical assessment of autism in high-risk 18-month-olds / Jessica BRIAN in Autism, 12-5 (September 2008)  

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Clinician's Manual on Autism Spectrum Disorder / Evdokia ANAGNOSTOU

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Comparative Analysis of Phenotypic and Genotypic Differences Between Individuals Affected by Regressive and Non-Regressive Autism: A Cross-Sectional Study / Alana IABONI ; Brett TROST ; Miriam REUTER ; Zsuzsa LINDENMAIER ; Azadeh KUSHKI ; Elizabeth KELLEY ; Jessica JONES ; Muhammad AYUB ; Stelios GEORGIADES ; Robert NICOLSON ; Elim CHAN ; Andrada CRETU ; Jessica BRIAN ; Evdokia ANAGNOSTOU in Autism Research, 18-6 (June 2025)  

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Comparative strengths and challenges on face-to-face and computer-based attention tasks in autistic and neurotypical toddlers / Lori-Ann R. SACREY in Autism Research, 16-8 (August 2023)  

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Concurrent Validity of the ABAS-II Questionnaire with the Vineland II Interview for Adaptive Behavior in a Pediatric ASD Sample: High Correspondence Despite Systematically Lower Scores / Annie DUPUIS in Journal of Autism and Developmental Disorders, 51-5 (May 2021)  

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Construct validity of the First-Year Inventory (FYI Version 2.0) in 12-month-olds at high-risk for Autism Spectrum Disorder / Helen LEE in Autism, 25-1 (January 2021)  

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