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Auteur Daniel N. KLEIN |
Documents disponibles écrits par cet auteur (30)
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The interaction between parenting and children's cortisol reactivity at age 3 predicts increases in children's internalizing and externalizing symptoms at age 6 / Chelsey S. BARRIOS in Development and Psychopathology, 29-4 (October 2017)
[article]
Titre : The interaction between parenting and children's cortisol reactivity at age 3 predicts increases in children's internalizing and externalizing symptoms at age 6 Type de document : Texte imprimé et/ou numérique Auteurs : Chelsey S. BARRIOS, Auteur ; Sara J. BUFFERD, Auteur ; Daniel N. KLEIN, Auteur ; Lea R. DOUGHERTY, Auteur Article en page(s) : p.1319-1331 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Little is known about the role of stress reactivity in the emergence of psychopathology across early childhood. In this longitudinal study, we tested the hypothesis that child cortisol reactivity at age 3 moderates associations between early parenting and children's internalizing and externalizing symptoms from age 3 to age 6. One hundred and sixty children were assessed at age 3, and 135 children were reassessed at age 6. At age 3, we exposed children to stress-inducing laboratory tasks, during which we obtained four salivary cortisol samples, and parental hostility was assessed using an observational parent–child interaction task. At ages 3 and 6, child psychiatric symptoms were assessed using a clinical interview with parents. The results indicated that the combination of high child cortisol reactivity and high observed parental hostility at age 3 was associated with greater concurrent externalizing symptoms at age 3 and predicted increases in internalizing and externalizing symptoms from age 3 to age 6. Findings highlight that increased stress reactivity, within the context of hostile parenting, plays a role in the emergence of psychopathology from preschool to school entry. En ligne : http://dx.doi.org/10.1017/s0954579417000293 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=312
in Development and Psychopathology > 29-4 (October 2017) . - p.1319-1331[article] The interaction between parenting and children's cortisol reactivity at age 3 predicts increases in children's internalizing and externalizing symptoms at age 6 [Texte imprimé et/ou numérique] / Chelsey S. BARRIOS, Auteur ; Sara J. BUFFERD, Auteur ; Daniel N. KLEIN, Auteur ; Lea R. DOUGHERTY, Auteur . - p.1319-1331.
Langues : Anglais (eng)
in Development and Psychopathology > 29-4 (October 2017) . - p.1319-1331
Index. décimale : PER Périodiques Résumé : Abstract Little is known about the role of stress reactivity in the emergence of psychopathology across early childhood. In this longitudinal study, we tested the hypothesis that child cortisol reactivity at age 3 moderates associations between early parenting and children's internalizing and externalizing symptoms from age 3 to age 6. One hundred and sixty children were assessed at age 3, and 135 children were reassessed at age 6. At age 3, we exposed children to stress-inducing laboratory tasks, during which we obtained four salivary cortisol samples, and parental hostility was assessed using an observational parent–child interaction task. At ages 3 and 6, child psychiatric symptoms were assessed using a clinical interview with parents. The results indicated that the combination of high child cortisol reactivity and high observed parental hostility at age 3 was associated with greater concurrent externalizing symptoms at age 3 and predicted increases in internalizing and externalizing symptoms from age 3 to age 6. Findings highlight that increased stress reactivity, within the context of hostile parenting, plays a role in the emergence of psychopathology from preschool to school entry. En ligne : http://dx.doi.org/10.1017/s0954579417000293 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=312 The serotonin transporter linked polymorphic region and brain-derived neurotrophic factor valine to methionine at position 66 polymorphisms and maternal history of depression: Associations with cognitive vulnerability to depression in childhood / Elizabeth P. HAYDEN in Development and Psychopathology, 25-3 (August 2013)
[article]
Titre : The serotonin transporter linked polymorphic region and brain-derived neurotrophic factor valine to methionine at position 66 polymorphisms and maternal history of depression: Associations with cognitive vulnerability to depression in childhood Type de document : Texte imprimé et/ou numérique Auteurs : Elizabeth P. HAYDEN, Auteur ; Thomas M. OLINO, Auteur ; Sara J. BUFFERD, Auteur ; Anna MILLER, Auteur ; Lea R. DOUGHERTY, Auteur ; Haroon I. SHEIKH, Auteur ; Shiva M. SINGH, Auteur ; Daniel N. KLEIN, Auteur Article en page(s) : p.587-598 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Preliminary work indicates that cognitive vulnerability to depression may be associated with variants of the serotonin transporter promoter polymorphism (5-HTTLPR) and the valine to methionine at position 66 (val66met) polymorphism of the brain-derived neurotrophic factor (BDNF) gene; however, existing reports come from small samples. The present study sought to replicate and extend this research in a sample of 375 community-dwelling children and their parents. Following a negative mood induction, children completed a self-referent encoding task tapping memory for positive and negative self-descriptive traits. Consistent with previous work, we found that children with at least one short variant of the 5-HTTLPR had enhanced memory for negative self-descriptive traits. The BDNF val66met polymorphism had no main effect but was moderated by maternal depression, such that children with a BDNF methionine allele had a heightened memory for negative self-descriptive traits when mothers had experienced depression during children's lifetimes; in contrast, children with a methionine allele had low recall of negative traits when mothers had no depression history. The findings provide further support for the notion that the 5-HTTLPR is associated with cognitive markers of depression vulnerability and that the BDNF methionine allele moderates children's sensitivity to contextual factors. En ligne : http://dx.doi.org/10.1017/S0954579413000035 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=210
in Development and Psychopathology > 25-3 (August 2013) . - p.587-598[article] The serotonin transporter linked polymorphic region and brain-derived neurotrophic factor valine to methionine at position 66 polymorphisms and maternal history of depression: Associations with cognitive vulnerability to depression in childhood [Texte imprimé et/ou numérique] / Elizabeth P. HAYDEN, Auteur ; Thomas M. OLINO, Auteur ; Sara J. BUFFERD, Auteur ; Anna MILLER, Auteur ; Lea R. DOUGHERTY, Auteur ; Haroon I. SHEIKH, Auteur ; Shiva M. SINGH, Auteur ; Daniel N. KLEIN, Auteur . - p.587-598.
Langues : Anglais (eng)
in Development and Psychopathology > 25-3 (August 2013) . - p.587-598
Index. décimale : PER Périodiques Résumé : Preliminary work indicates that cognitive vulnerability to depression may be associated with variants of the serotonin transporter promoter polymorphism (5-HTTLPR) and the valine to methionine at position 66 (val66met) polymorphism of the brain-derived neurotrophic factor (BDNF) gene; however, existing reports come from small samples. The present study sought to replicate and extend this research in a sample of 375 community-dwelling children and their parents. Following a negative mood induction, children completed a self-referent encoding task tapping memory for positive and negative self-descriptive traits. Consistent with previous work, we found that children with at least one short variant of the 5-HTTLPR had enhanced memory for negative self-descriptive traits. The BDNF val66met polymorphism had no main effect but was moderated by maternal depression, such that children with a BDNF methionine allele had a heightened memory for negative self-descriptive traits when mothers had experienced depression during children's lifetimes; in contrast, children with a methionine allele had low recall of negative traits when mothers had no depression history. The findings provide further support for the notion that the 5-HTTLPR is associated with cognitive markers of depression vulnerability and that the BDNF methionine allele moderates children's sensitivity to contextual factors. En ligne : http://dx.doi.org/10.1017/S0954579413000035 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=210 Three-variable systems: An integrative moderation and mediation framework for developmental psychopathology / Brandon L. GOLDSTEIN in Development and Psychopathology, 35-1 (February 2023)
[article]
Titre : Three-variable systems: An integrative moderation and mediation framework for developmental psychopathology Type de document : Texte imprimé et/ou numérique Auteurs : Brandon L. GOLDSTEIN, Auteur ; Megan C. FINSAAS, Auteur ; Thomas M. OLINO, Auteur ; Roman KOTOV, Auteur ; Damion J. GRASSO, Auteur ; Daniel N. KLEIN, Auteur Article en page(s) : p.12-23 Langues : Anglais (eng) Mots-clés : developmental psychopathology longitudinal research mediation moderation risk factors Index. décimale : PER Périodiques Résumé : In this article, we consider an often overlooked model that combines mediation and moderation to explain how a third variable can relate to a risk factor-psychopathology relationship. We refer to it as moderation and mediation in a three-variable system. We describe how this model is relevant to studying vulnerability factors and how it may advance developmental psychopathology research. To illustrate the value of this approach, we provide several examples where this model may be applicable, such as the relationships among parental externalizing pathology, harsh parenting, and offspring psychopathology as well as between neuroticism, stressful life events, and depression. We discuss possible reasons why this model has not gained traction and attempt to clarify and dispel those concerns. We provide guidance and recommendations for when to consider this model for a given data set and point toward existing resources for testing this model that have been developed by statisticians and other methodologists. Lastly, we describe important caveats, limitations, and considerations for making this approach most useful for developmental research. Overall, our goal in presenting this information to developmental psychopathology researchers is to encourage testing moderation and mediation in a three-variable system with the aim of advancing analytic strategies for studying vulnerability factors. En ligne : https://doi.org/10.1017/S0954579421000493 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499
in Development and Psychopathology > 35-1 (February 2023) . - p.12-23[article] Three-variable systems: An integrative moderation and mediation framework for developmental psychopathology [Texte imprimé et/ou numérique] / Brandon L. GOLDSTEIN, Auteur ; Megan C. FINSAAS, Auteur ; Thomas M. OLINO, Auteur ; Roman KOTOV, Auteur ; Damion J. GRASSO, Auteur ; Daniel N. KLEIN, Auteur . - p.12-23.
Langues : Anglais (eng)
in Development and Psychopathology > 35-1 (February 2023) . - p.12-23
Mots-clés : developmental psychopathology longitudinal research mediation moderation risk factors Index. décimale : PER Périodiques Résumé : In this article, we consider an often overlooked model that combines mediation and moderation to explain how a third variable can relate to a risk factor-psychopathology relationship. We refer to it as moderation and mediation in a three-variable system. We describe how this model is relevant to studying vulnerability factors and how it may advance developmental psychopathology research. To illustrate the value of this approach, we provide several examples where this model may be applicable, such as the relationships among parental externalizing pathology, harsh parenting, and offspring psychopathology as well as between neuroticism, stressful life events, and depression. We discuss possible reasons why this model has not gained traction and attempt to clarify and dispel those concerns. We provide guidance and recommendations for when to consider this model for a given data set and point toward existing resources for testing this model that have been developed by statisticians and other methodologists. Lastly, we describe important caveats, limitations, and considerations for making this approach most useful for developmental research. Overall, our goal in presenting this information to developmental psychopathology researchers is to encourage testing moderation and mediation in a three-variable system with the aim of advancing analytic strategies for studying vulnerability factors. En ligne : https://doi.org/10.1017/S0954579421000493 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499 Tonic and phasic irritability in 6-year-old children: differential correlates and outcomes / Jamilah SILVER in Journal of Child Psychology and Psychiatry, 64-2 (February 2023)
[article]
Titre : Tonic and phasic irritability in 6-year-old children: differential correlates and outcomes Type de document : Texte imprimé et/ou numérique Auteurs : Jamilah SILVER, Auteur ; Daniel M. MACKIN, Auteur ; Sara J. BUFFERD, Auteur ; Lea R. DOUGHERTY, Auteur ; Brandon L. GOLDSTEIN, Auteur ; Gabrielle A. CARLSON, Auteur ; Daniel N. KLEIN, Auteur Article en page(s) : p.234-243 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Objective Irritability is a common and clinically important problem in children and adolescents and a risk factor for later psychopathology and impairment. Irritability can manifest in both tonic (e.g., irritable, touchy mood) and phasic (e.g., temper outburst) forms, and recent studies of adolescents suggest that they predict different outcomes. However, no studies have examined whether tonic and phasic irritability are empirically distinguishable in 6-year-old children and whether they have distinct correlates and outcomes. Method We utilized data from a longitudinal study of an unselected community sample of four hundred fifty-two 6-year-olds followed at 3-year intervals to age 15. We conducted confirmatory factor analysis (CFA) using relevant items from a diagnostic interview and several parent-report inventories. Results The CFA identified dimensions that were consistent with tonic and phasic irritability. Tonic irritability was independently associated with concurrent parent-reported temperamental negative affectivity and internalizing and externalizing disorders at age 6 and predicted higher rates of internalizing psychopathology, and suicidal ideation, in adolescence. Phasic irritability was independently associated with concurrent parent-reported temperamental negative affectivity, surgency, and low effortful control, maladaptive parenting styles and practices, and externalizing disorders at age 6, and predicted higher rates of externalizing psychopathology in adolescence. Conclusions Tonic and phasic irritability in 6-year-old children appear to be distinguishable constructs with different temperament and parenting correlates and psychopathological outcomes. Distinguishing these components has implications for research on the etiology and pathophysiology of irritability and developing effective treatments. En ligne : https://doi.org/10.1111/jcpp.13688 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492
in Journal of Child Psychology and Psychiatry > 64-2 (February 2023) . - p.234-243[article] Tonic and phasic irritability in 6-year-old children: differential correlates and outcomes [Texte imprimé et/ou numérique] / Jamilah SILVER, Auteur ; Daniel M. MACKIN, Auteur ; Sara J. BUFFERD, Auteur ; Lea R. DOUGHERTY, Auteur ; Brandon L. GOLDSTEIN, Auteur ; Gabrielle A. CARLSON, Auteur ; Daniel N. KLEIN, Auteur . - p.234-243.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 64-2 (February 2023) . - p.234-243
Index. décimale : PER Périodiques Résumé : Objective Irritability is a common and clinically important problem in children and adolescents and a risk factor for later psychopathology and impairment. Irritability can manifest in both tonic (e.g., irritable, touchy mood) and phasic (e.g., temper outburst) forms, and recent studies of adolescents suggest that they predict different outcomes. However, no studies have examined whether tonic and phasic irritability are empirically distinguishable in 6-year-old children and whether they have distinct correlates and outcomes. Method We utilized data from a longitudinal study of an unselected community sample of four hundred fifty-two 6-year-olds followed at 3-year intervals to age 15. We conducted confirmatory factor analysis (CFA) using relevant items from a diagnostic interview and several parent-report inventories. Results The CFA identified dimensions that were consistent with tonic and phasic irritability. Tonic irritability was independently associated with concurrent parent-reported temperamental negative affectivity and internalizing and externalizing disorders at age 6 and predicted higher rates of internalizing psychopathology, and suicidal ideation, in adolescence. Phasic irritability was independently associated with concurrent parent-reported temperamental negative affectivity, surgency, and low effortful control, maladaptive parenting styles and practices, and externalizing disorders at age 6, and predicted higher rates of externalizing psychopathology in adolescence. Conclusions Tonic and phasic irritability in 6-year-old children appear to be distinguishable constructs with different temperament and parenting correlates and psychopathological outcomes. Distinguishing these components has implications for research on the etiology and pathophysiology of irritability and developing effective treatments. En ligne : https://doi.org/10.1111/jcpp.13688 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492 Transdiagnostic factors and pathways to multifinality: The error-related negativity predicts whether preschool irritability is associated with internalizing versus externalizing symptoms at age 9 / Ellen M. KESSEL in Development and Psychopathology, 28-4 pt1 (November 2016)
[article]
Titre : Transdiagnostic factors and pathways to multifinality: The error-related negativity predicts whether preschool irritability is associated with internalizing versus externalizing symptoms at age 9 Type de document : Texte imprimé et/ou numérique Auteurs : Ellen M. KESSEL, Auteur ; Alexandria MEYER, Auteur ; Greg HAJCAK, Auteur ; Lea R. DOUGHERTY, Auteur ; Dana C. TORPEY-NEWMAN, Auteur ; Gabrielle A. CARLSON, Auteur ; Daniel N. KLEIN, Auteur Article en page(s) : p.913-926 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : There is increasing interest among developmental psychopathologists in broad transdiagnostic factors that give rise to a wide array of clinical presentations (multifinality), but little is known about how these processes lead to particular psychopathological manifestations over the course of development. We examined whether individual differences in the error-related negativity (?ERN), a neural indicator of error monitoring, predicts whether early persistent irritability, a prototypical transdiagnostic construct, is associated with later internalizing versus externalizing outcomes. When children were 3 years old, mothers were interviewed about children's persistent irritability and completed questionnaires about their children's psychopathology. Three years later, EEG was recorded while children performed a go/no-go task to measure the ?ERN. When children were approximately 9 years old, mothers again completed questionnaires about their children's psychopathology. The results indicated that among children who were persistently irritable at age 3, an enhanced or more negative ?ERN at age 6 predicted the development of internalizing symptoms at age 9, whereas a blunted or smaller ?ERN at age 6 predicted the development of externalizing symptoms. Our results suggest that variation in error monitoring predicts, and may even shape, the expression of persistent irritability and differentiates developmental trajectories from preschool persistent irritability to internalizing versus externalizing outcomes in middle to late childhood. En ligne : http://dx.doi.org/10.1017/s0954579416000626 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294
in Development and Psychopathology > 28-4 pt1 (November 2016) . - p.913-926[article] Transdiagnostic factors and pathways to multifinality: The error-related negativity predicts whether preschool irritability is associated with internalizing versus externalizing symptoms at age 9 [Texte imprimé et/ou numérique] / Ellen M. KESSEL, Auteur ; Alexandria MEYER, Auteur ; Greg HAJCAK, Auteur ; Lea R. DOUGHERTY, Auteur ; Dana C. TORPEY-NEWMAN, Auteur ; Gabrielle A. CARLSON, Auteur ; Daniel N. KLEIN, Auteur . - p.913-926.
Langues : Anglais (eng)
in Development and Psychopathology > 28-4 pt1 (November 2016) . - p.913-926
Index. décimale : PER Périodiques Résumé : There is increasing interest among developmental psychopathologists in broad transdiagnostic factors that give rise to a wide array of clinical presentations (multifinality), but little is known about how these processes lead to particular psychopathological manifestations over the course of development. We examined whether individual differences in the error-related negativity (?ERN), a neural indicator of error monitoring, predicts whether early persistent irritability, a prototypical transdiagnostic construct, is associated with later internalizing versus externalizing outcomes. When children were 3 years old, mothers were interviewed about children's persistent irritability and completed questionnaires about their children's psychopathology. Three years later, EEG was recorded while children performed a go/no-go task to measure the ?ERN. When children were approximately 9 years old, mothers again completed questionnaires about their children's psychopathology. The results indicated that among children who were persistently irritable at age 3, an enhanced or more negative ?ERN at age 6 predicted the development of internalizing symptoms at age 9, whereas a blunted or smaller ?ERN at age 6 predicted the development of externalizing symptoms. Our results suggest that variation in error monitoring predicts, and may even shape, the expression of persistent irritability and differentiates developmental trajectories from preschool persistent irritability to internalizing versus externalizing outcomes in middle to late childhood. En ligne : http://dx.doi.org/10.1017/s0954579416000626 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=294