Alexithymia in Adolescents with Autism Spectrum Disorder: Its Relationship to Internalising Difficulties, Sensory Modulation and Social Cognition / Bosiljka MILOSAVLJEVIC in Journal of Autism and Developmental Disorders, 46-4 (April 2016) 

Public ISBD [article]  in Journal of Autism and Developmental Disorders > 46-4 (April 2016) . - p.1354-1367 Titre : Alexithymia in Adolescents with Autism Spectrum Disorder: Its Relationship to Internalising Difficulties, Sensory Modulation and Social Cognition Type de document : texte imprimé Auteurs : Bosiljka MILOSAVLJEVIC, Auteur ; Virginia CARTER LENO, Auteur ; Emily SIMONOFF, Auteur ; Gillian BAIRD, Auteur ; Andrew PICKLES, Auteur ; Catherine R. G. JONES, Auteur ; Catherine ERSKINE, Auteur ; Tony CHARMAN, Auteur ; Francesca HAPPE, Auteur Article en page(s) : p.1354-1367 Langues : Anglais (eng) Mots-clés : Alexithymia  Autism spectrum disorder  Emotion recognition  Theory of mind  Anxiety  Sensory processing Index. décimale : PER Périodiques Résumé : Alexithymia is a personality trait frequently found in adults with autism spectrum disorder (ASD), and has been linked to impairments in emotion recognition and empathy. The presentation of alexithymia within ASD at younger ages remains unexplored, and was examined in the present study. Alexithymia rates were significantly elevated in ASD (55 %; 31/56 scoring above cut-off) versus non-ASD adolescents (16 %; 5/32 scoring above cut-off). Within individuals with ASD, alexithymia was associated with increased self-reported anxiety, parent-reported emotional difficulties, self-reported sensory processing atypicalities, and poorer emotion recognition, but was not associated with theory of mind ability. Overall, our results suggest that alexithymia is highly prevalent, and has selective cognitive correlates in young people with ASD. En ligne : http://dx.doi.org/10.1007/s10803-015-2670-8 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2848 [article] Alexithymia in Adolescents with Autism Spectrum Disorder: Its Relationship to Internalising Difficulties, Sensory Modulation and Social Cognition [texte imprimé] / Bosiljka MILOSAVLJEVIC, Auteur ; Virginia CARTER LENO, Auteur ; Emily SIMONOFF, Auteur ; Gillian BAIRD, Auteur ; Andrew PICKLES, Auteur ; Catherine R. G. JONES, Auteur ; Catherine ERSKINE, Auteur ; Tony CHARMAN, Auteur ; Francesca HAPPE, Auteur . - p.1354-1367. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 46-4 (April 2016) . - p.1354-1367 Mots-clés : Alexithymia  Autism spectrum disorder  Emotion recognition  Theory of mind  Anxiety  Sensory processing Index. décimale : PER Périodiques Résumé : Alexithymia is a personality trait frequently found in adults with autism spectrum disorder (ASD), and has been linked to impairments in emotion recognition and empathy. The presentation of alexithymia within ASD at younger ages remains unexplored, and was examined in the present study. Alexithymia rates were significantly elevated in ASD (55 %; 31/56 scoring above cut-off) versus non-ASD adolescents (16 %; 5/32 scoring above cut-off). Within individuals with ASD, alexithymia was associated with increased self-reported anxiety, parent-reported emotional difficulties, self-reported sensory processing atypicalities, and poorer emotion recognition, but was not associated with theory of mind ability. Overall, our results suggest that alexithymia is highly prevalent, and has selective cognitive correlates in young people with ASD. En ligne : http://dx.doi.org/10.1007/s10803-015-2670-8 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2848

An emerging income differential for adolescent emotional problems / Emma GORE LANGTON in Journal of Child Psychology and Psychiatry, 52-10 (October 2011) 

Public ISBD [article]  in Journal of Child Psychology and Psychiatry > 52-10 (October 2011) . - p.1081-1088 Titre : An emerging income differential for adolescent emotional problems Type de document : texte imprimé Auteurs : Emma GORE LANGTON, Auteur ; Stephan COLLISHAW, Auteur ; Robert GOODMAN, Auteur ; Andrew PICKLES, Auteur ; Barbara MAUGHAN, Auteur Année de publication : 2011 Article en page(s) : p.1081-1088 Langues : Anglais (eng) Mots-clés : Income gradient;adolescence;emotional problems;sociodemographic risk factors  family factors  National Child Development Study  British Cohort Study  British Child and Adolescent Mental Health Surveys Index. décimale : PER Périodiques Résumé : Background:  While there is considerable evidence of income gradients in child and adolescent behaviour problems, evidence relating to children and young people’s emotional difficulties is more mixed. Older studies reported no income differentials, while recent reports suggest that adolescents from low-income families are more likely to experience emotional difficulties than their more affluent peers. Methods:  We compared the association between low- versus medium-/high-family income and parent-reported emotional difficulties in 15- and 16-year-olds in three large nationally representative cohorts studied in 1974, 1986 and 1999/2004. We then examined whether increases in the income differential could be accounted for by changes in the association of a range of sociodemographic factors (family type or size, maternal education or housing tenure) with either family income or emotional difficulties. Finally, in the most recent cohorts, we considered whether the effects of these sociodemographic variables were mediated by more proximal family factors (maternal distress, stressful life events or family dysfunction). Results:  An increasing income differential in adolescent emotional problems emerged over the period, with standardized coefficients for associations with low income increasing from .07 in 1974 and 1986 to .30 in 1999/2004. This was due partially (∼10%) to sociodemographic risk factors for emotional difficulties becoming more strongly associated with low-income families over time, and partially (∼40%) to the increasing impact of these risk factors. In the most recent cohorts, about 40% of the effects of sociodemographic risks appear to have been mediated by more proximal family factors. Conclusions:  These findings have implications for our understanding of the health burden of emotional problems, recognition of the health burden associated with inequality and public concern about the consequences of social change. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02447.x Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1429 [article] An emerging income differential for adolescent emotional problems [texte imprimé] / Emma GORE LANGTON, Auteur ; Stephan COLLISHAW, Auteur ; Robert GOODMAN, Auteur ; Andrew PICKLES, Auteur ; Barbara MAUGHAN, Auteur . - 2011 . - p.1081-1088. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 52-10 (October 2011) . - p.1081-1088 Mots-clés : Income gradient;adolescence;emotional problems;sociodemographic risk factors  family factors  National Child Development Study  British Cohort Study  British Child and Adolescent Mental Health Surveys Index. décimale : PER Périodiques Résumé : Background:  While there is considerable evidence of income gradients in child and adolescent behaviour problems, evidence relating to children and young people’s emotional difficulties is more mixed. Older studies reported no income differentials, while recent reports suggest that adolescents from low-income families are more likely to experience emotional difficulties than their more affluent peers. Methods:  We compared the association between low- versus medium-/high-family income and parent-reported emotional difficulties in 15- and 16-year-olds in three large nationally representative cohorts studied in 1974, 1986 and 1999/2004. We then examined whether increases in the income differential could be accounted for by changes in the association of a range of sociodemographic factors (family type or size, maternal education or housing tenure) with either family income or emotional difficulties. Finally, in the most recent cohorts, we considered whether the effects of these sociodemographic variables were mediated by more proximal family factors (maternal distress, stressful life events or family dysfunction). Results:  An increasing income differential in adolescent emotional problems emerged over the period, with standardized coefficients for associations with low income increasing from .07 in 1974 and 1986 to .30 in 1999/2004. This was due partially (∼10%) to sociodemographic risk factors for emotional difficulties becoming more strongly associated with low-income families over time, and partially (∼40%) to the increasing impact of these risk factors. In the most recent cohorts, about 40% of the effects of sociodemographic risks appear to have been mediated by more proximal family factors. Conclusions:  These findings have implications for our understanding of the health burden of emotional problems, recognition of the health burden associated with inequality and public concern about the consequences of social change. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02447.x Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1429

Annual Research Review: Threats to the validity of child psychiatry and psychology / Michael RUTTER in Journal of Child Psychology and Psychiatry, 57-3 (March 2016) 

Public ISBD [article]  in Journal of Child Psychology and Psychiatry > 57-3 (March 2016) . - p.398-416 Titre : Annual Research Review: Threats to the validity of child psychiatry and psychology Type de document : texte imprimé Auteurs : Michael RUTTER, Auteur ; Andrew PICKLES, Auteur Article en page(s) : p.398-416 Langues : Anglais (eng) Mots-clés : Classification  diagnosis  genetics  epigenetics  bioinformatics  brain imaging  biomarkers  neural networks Index. décimale : PER Périodiques Résumé : Background Suggestions have been made that many claims concern false-positive findings in the field of child psychology and psychiatry. Findings The literature was searched for concepts and findings on the validity of child psychiatry and psychology. Substantial progress has been made in some, but not all, areas and considerable challenges remain in all. Conclusions The two major threats to validity concern the inability to examine brain tissues in life and the evidence that there is a high overlap among disorders. We emphasize the need to follow published guidelines on preplanned analyses and we note the dangers associated with unregulated flexibility in data analysis. We note the very important clinical and developmental findings that have been ignored, perhaps partly because of an excessive focus on technologies. Nevertheless, we are positive about both the accomplishments and the ways in which challenges are being met. En ligne : http://dx.doi.org/10.1111/jcpp.12461 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2824 [article] Annual Research Review: Threats to the validity of child psychiatry and psychology [texte imprimé] / Michael RUTTER, Auteur ; Andrew PICKLES, Auteur . - p.398-416. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 57-3 (March 2016) . - p.398-416 Mots-clés : Classification  diagnosis  genetics  epigenetics  bioinformatics  brain imaging  biomarkers  neural networks Index. décimale : PER Périodiques Résumé : Background Suggestions have been made that many claims concern false-positive findings in the field of child psychology and psychiatry. Findings The literature was searched for concepts and findings on the validity of child psychiatry and psychology. Substantial progress has been made in some, but not all, areas and considerable challenges remain in all. Conclusions The two major threats to validity concern the inability to examine brain tissues in life and the evidence that there is a high overlap among disorders. We emphasize the need to follow published guidelines on preplanned analyses and we note the dangers associated with unregulated flexibility in data analysis. We note the very important clinical and developmental findings that have been ignored, perhaps partly because of an excessive focus on technologies. Nevertheless, we are positive about both the accomplishments and the ways in which challenges are being met. En ligne : http://dx.doi.org/10.1111/jcpp.12461 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2824

Autistic symptomatology and language ability in autism spectrum disorder and specific language impairment / Tom LOUCAS in Journal of Child Psychology and Psychiatry, 49-11 (November 2008) 

Public ISBD [article]  in Journal of Child Psychology and Psychiatry > 49-11 (November 2008) . - p.1184-1192 Titre : Autistic symptomatology and language ability in autism spectrum disorder and specific language impairment Type de document : texte imprimé Auteurs : Tom LOUCAS, Auteur ; Tony CHARMAN, Auteur ; Emily SIMONOFF, Auteur ; Andrew PICKLES, Auteur ; Gillian BAIRD, Auteur ; Susie CHANDLER, Auteur ; David MELDRUM, Auteur Article en page(s) : p.1184-1192 Langues : Anglais (eng) Mots-clés : Autistic-disorder specific-language-impairment SNAP-cohort Index. décimale : PER Périodiques Résumé : Background: Autism spectrum disorders (ASD) and specific language impairment (SLI) are common developmental disorders characterised by deficits in language and communication. The nature of the relationship between them continues to be a matter of debate. This study investigates whether the co-occurrence of ASD and language impairment is associated with differences in severity or pattern of autistic symptomatology or language profile. Methods: Participants (N = 97) were drawn from a total population cohort of 56,946 screened as part of study to ascertain the prevalence of ASD, aged 9 to 14 years. All children received an ICD-10 clinical diagnosis of ASD or No ASD. Children with nonverbal IQ ≥80 were divided into those with a language impairment (language score of 77 or less) and those without, creating three groups: children with ASD and a language impairment (ALI; N = 41), those with ASD and but no language impairment (ANL; N = 31) and those with language impairment but no ASD (SLI; N = 25). Results: Children with ALI did not show more current autistic symptoms than those with ANL. Children with SLI were well below the threshold for ASD. Their social adaptation was higher than the ASD groups, but still nearly 2 SD below average. In ALI the combination of ASD and language impairment was associated with weaker functional communication and more severe receptive language difficulties than those found in SLI. Receptive and expressive language were equally impaired in ALI, whereas in SLI receptive language was stronger than expressive. Conclusions: Co-occurrence of ASD and language impairment is not associated with increased current autistic symptomatology but appears to be associated with greater impairment in receptive language and functional communication. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01951.x Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=6334 [article] Autistic symptomatology and language ability in autism spectrum disorder and specific language impairment [texte imprimé] / Tom LOUCAS, Auteur ; Tony CHARMAN, Auteur ; Emily SIMONOFF, Auteur ; Andrew PICKLES, Auteur ; Gillian BAIRD, Auteur ; Susie CHANDLER, Auteur ; David MELDRUM, Auteur . - p.1184-1192. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 49-11 (November 2008) . - p.1184-1192 Mots-clés : Autistic-disorder specific-language-impairment SNAP-cohort Index. décimale : PER Périodiques Résumé : Background: Autism spectrum disorders (ASD) and specific language impairment (SLI) are common developmental disorders characterised by deficits in language and communication. The nature of the relationship between them continues to be a matter of debate. This study investigates whether the co-occurrence of ASD and language impairment is associated with differences in severity or pattern of autistic symptomatology or language profile. Methods: Participants (N = 97) were drawn from a total population cohort of 56,946 screened as part of study to ascertain the prevalence of ASD, aged 9 to 14 years. All children received an ICD-10 clinical diagnosis of ASD or No ASD. Children with nonverbal IQ ≥80 were divided into those with a language impairment (language score of 77 or less) and those without, creating three groups: children with ASD and a language impairment (ALI; N = 41), those with ASD and but no language impairment (ANL; N = 31) and those with language impairment but no ASD (SLI; N = 25). Results: Children with ALI did not show more current autistic symptoms than those with ANL. Children with SLI were well below the threshold for ASD. Their social adaptation was higher than the ASD groups, but still nearly 2 SD below average. In ALI the combination of ASD and language impairment was associated with weaker functional communication and more severe receptive language difficulties than those found in SLI. Receptive and expressive language were equally impaired in ALI, whereas in SLI receptive language was stronger than expressive. Conclusions: Co-occurrence of ASD and language impairment is not associated with increased current autistic symptomatology but appears to be associated with greater impairment in receptive language and functional communication. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2008.01951.x Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=6334

Between a ROC and a hard place: decision making and making decisions about using the SCQ / Christina M. CORSELLO in Journal of Child Psychology and Psychiatry, 48-9 (September 2007) 

Public ISBD [article]  in Journal of Child Psychology and Psychiatry > 48-9 (September 2007) . - p.932–940 Titre : Between a ROC and a hard place: decision making and making decisions about using the SCQ Type de document : texte imprimé Auteurs : Christina M. CORSELLO, Auteur ; Catherine LORD, Auteur ; Andrew PICKLES, Auteur ; Susan RISI, Auteur ; Vanessa HUS, Auteur ; Edwin H. Jr COOK, Auteur ; Bennett L. LEVENTHAL, Auteur Article en page(s) : p.932–940 Langues : Anglais (eng) Mots-clés : Autistic-disorder diagnosis screening Social-Communication-Questionnaire Index. décimale : PER Périodiques Résumé : Background: The Social Communication Questionnaire (SCQ), formerly the Autism Screening Questionnaire (ASQ), is based on a well-validated parent interview, the Autism Diagnostic Interview (ADI). It has shown promise as a screening measure for autism spectrum disorders (ASDs) in a research-referred older sample, though recent studies with younger children reported lower sensitivities when using the suggested cutoff of ≥15 to differentiate ASDs from children with nonspectrum disorders (NS). Methods: Diagnostic discrimination of the SCQ was evaluated alone and in combination with the ADOS (Autism Diagnostic Observation Schedule) in a clinical and research-referred sample of 590 children and adolescents (2 to 16 years), with best estimate consensus diagnoses of autism, pervasive developmental disorder, not otherwise specified (PDD-NOS) and non-ASD disorders. The SCQ was completed before the evaluation in most cases. Performance of the SCQ was also compared with the Autism Diagnostic Interview – Revised (ADI-R). Results: Absolute scores and sensitivity in the younger children and specificity for all groups were lower than reported in the original study. Using receiver operating curves (ROC) to examine the area under the curve (AUC), the SCQ was more similar to the ADI-R total score in differentiating ASD from NS disorders in the older (8–10, >11) than younger age groups (<5, 5–7). Lowering the cutoff score in the 2 younger groups improved sensitivity, with specificity remaining relatively low in all groups. Using the SCQ in combination with the ADOS resulted in improved specificity. Diagnostic discrimination was best using the ADI-R and ADOS in combination. Conclusions: Those interested in using the SCQ should consider adjusting cutoff scores according to age and purpose, and using it in combination with another measure. Sensitivity or specificity may be prioritized for research or screening depending on goals. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01762.x Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1641 [article] Between a ROC and a hard place: decision making and making decisions about using the SCQ [texte imprimé] / Christina M. CORSELLO, Auteur ; Catherine LORD, Auteur ; Andrew PICKLES, Auteur ; Susan RISI, Auteur ; Vanessa HUS, Auteur ; Edwin H. Jr COOK, Auteur ; Bennett L. LEVENTHAL, Auteur . - p.932–940. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 48-9 (September 2007) . - p.932–940 Mots-clés : Autistic-disorder diagnosis screening Social-Communication-Questionnaire Index. décimale : PER Périodiques Résumé : Background: The Social Communication Questionnaire (SCQ), formerly the Autism Screening Questionnaire (ASQ), is based on a well-validated parent interview, the Autism Diagnostic Interview (ADI). It has shown promise as a screening measure for autism spectrum disorders (ASDs) in a research-referred older sample, though recent studies with younger children reported lower sensitivities when using the suggested cutoff of ≥15 to differentiate ASDs from children with nonspectrum disorders (NS). Methods: Diagnostic discrimination of the SCQ was evaluated alone and in combination with the ADOS (Autism Diagnostic Observation Schedule) in a clinical and research-referred sample of 590 children and adolescents (2 to 16 years), with best estimate consensus diagnoses of autism, pervasive developmental disorder, not otherwise specified (PDD-NOS) and non-ASD disorders. The SCQ was completed before the evaluation in most cases. Performance of the SCQ was also compared with the Autism Diagnostic Interview – Revised (ADI-R). Results: Absolute scores and sensitivity in the younger children and specificity for all groups were lower than reported in the original study. Using receiver operating curves (ROC) to examine the area under the curve (AUC), the SCQ was more similar to the ADI-R total score in differentiating ASD from NS disorders in the older (8–10, >11) than younger age groups (<5, 5–7). Lowering the cutoff score in the 2 younger groups improved sensitivity, with specificity remaining relatively low in all groups. Using the SCQ in combination with the ADOS resulted in improved specificity. Diagnostic discrimination was best using the ADI-R and ADOS in combination. Conclusions: Those interested in using the SCQ should consider adjusting cutoff scores according to age and purpose, and using it in combination with another measure. Sensitivity or specificity may be prioritized for research or screening depending on goals. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01762.x Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1641

Beyond intervention into daily life: A systematic review of generalisation following social communication interventions for young children with autism / Sophie CARRUTHERS in Autism Research, 13-4 (April 2020) 

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Co-occurring Psychiatric Disorders in Preschool and Elementary School-Aged Children with Autism Spectrum Disorder / Fernando SALAZAR in Journal of Autism and Developmental Disorders, 45-8 (August 2015) 

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Communication and Social Deficits in Relatives of Individuals with SLI and Relatives of Individuals with ASD / Andrew PICKLES in Journal of Autism and Developmental Disorders, 43-1 (January 2013) 

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Comparing service use and costs among adolescents with autism spectrum disorders, special needs and typical development / Barbara BARRETT in Autism, 19-5 (July 2015) 

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Conduct problems co-occur with hyperactivity in children with language impairment: A longitudinal study from childhood to adolescence / Andrew PICKLES in Autism & Developmental Language Impairments, 1 (January-December 2016) 

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Dual Cognitive and Biological Correlates of Anxiety in Autism Spectrum Disorders / Matthew J. HOLLOCKS in Journal of Autism and Developmental Disorders, 46-10 (October 2016) 

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Early Developmental Regression in Autism Spectrum Disorder: Evidence from an International Multiplex Sample / Jeremy R. PARR in Journal of Autism and Developmental Disorders, 41-3 (March 2011) 

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Early gross motor skills predict the subsequent development of language in children with autism spectrum disorder / Rachael BEDFORD in Autism Research, 9-9 (September 2016) 

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Everyday Memory’ Impairments in Autism Spectrum Disorders / Catherine R.G. JONES in Journal of Autism and Developmental Disorders, 41-4 (April 2011) 

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Evidence for interplay between genes and parenting on infant temperament in the first year of life: monoamine oxidase A polymorphism moderates effects of maternal sensitivity on infant anger proneness / Andrew PICKLES in Journal of Child Psychology and Psychiatry, 54-12 (December 2013) 

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