Documents disponibles écrits par cet auteur

Adaptive Behavior Ratings Correlate With Symptomatology and IQ Among Individuals With High-Functioning Autism Spectrum Disorders / Lauren E. KENWORTHY in Journal of Autism and Developmental Disorders, 40-4 (April 2010) 

Public ISBD [article]  in Journal of Autism and Developmental Disorders > 40-4 (April 2010) . - p.416-423 Titre : Adaptive Behavior Ratings Correlate With Symptomatology and IQ Among Individuals With High-Functioning Autism Spectrum Disorders Type de document : texte imprimé Auteurs : Lauren E. KENWORTHY, Auteur ; Gregory L. WALLACE, Auteur ; Alex MARTIN, Auteur ; Laura CASE, Auteur ; Madeline B. HARMS, Auteur Article en page(s) : p.416-423 Langues : Anglais (eng) Mots-clés : Autism Adaptive-behavior Social-skills IQ Symptomatology Asperger’s-syndrome Index. décimale : PER Périodiques Résumé : Caregiver report on the Adaptive Behavior Assessment System-II (ABAS) for 40 high-functioning individuals with Autism Spectrum Disorders (ASD) and 30 typically developing (TD) individuals matched for age, IQ, and sex ratio revealed global adaptive behavior deficits in ASD, with social skills impairments particularly prominent. Within the ASD group, adaptive communication skills were positively related to IQ while global adaptive functioning was negatively associated with autism symptomatology. Autistic behavior ratings related negatively to ABAS scores in the TD but not the ASD group. This investigation demonstrates: the utility of an adaptive functioning checklist for capturing impairments, even in high-functioning individuals with ASD; and that a relationship between social abilities and autism exists independently of intelligence. En ligne : http://dx.doi.org/10.1007/s10803-009-0911-4 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=9919 [article] Adaptive Behavior Ratings Correlate With Symptomatology and IQ Among Individuals With High-Functioning Autism Spectrum Disorders [texte imprimé] / Lauren E. KENWORTHY, Auteur ; Gregory L. WALLACE, Auteur ; Alex MARTIN, Auteur ; Laura CASE, Auteur ; Madeline B. HARMS, Auteur . - p.416-423. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 40-4 (April 2010) . - p.416-423 Mots-clés : Autism Adaptive-behavior Social-skills IQ Symptomatology Asperger’s-syndrome Index. décimale : PER Périodiques Résumé : Caregiver report on the Adaptive Behavior Assessment System-II (ABAS) for 40 high-functioning individuals with Autism Spectrum Disorders (ASD) and 30 typically developing (TD) individuals matched for age, IQ, and sex ratio revealed global adaptive behavior deficits in ASD, with social skills impairments particularly prominent. Within the ASD group, adaptive communication skills were positively related to IQ while global adaptive functioning was negatively associated with autism symptomatology. Autistic behavior ratings related negatively to ABAS scores in the TD but not the ASD group. This investigation demonstrates: the utility of an adaptive functioning checklist for capturing impairments, even in high-functioning individuals with ASD; and that a relationship between social abilities and autism exists independently of intelligence. En ligne : http://dx.doi.org/10.1007/s10803-009-0911-4 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=9919

Aging and autism spectrum disorder: Evidence from the broad autism phenotype / Gregory L. WALLACE in Autism Research, 9-12 (December 2016) 

Public ISBD [article]  in Autism Research > 9-12 (December 2016) . - p.1294-1303 Titre : Aging and autism spectrum disorder: Evidence from the broad autism phenotype Type de document : texte imprimé Auteurs : Gregory L. WALLACE, Auteur ; Jessica BUDGETT, Auteur ; Rebecca A. CHARLTON, Auteur Article en page(s) : p.1294-1303 Langues : Anglais (eng) Mots-clés : broad autism phenotype  autism  aging  older adulthood  executive function  anxiety  depression  social support Index. décimale : PER Périodiques Résumé : This study investigated for the first time the broad autism phenotype (BAP) in the context of older adulthood and its associations with real-world executive function, social support, and both depression and anxiety symptomatology. Based on self-ratings of autistic traits, 66 older adults (60+ years old, range?=?61–88) were split into BAP (n?=?20) and control (n?=?46) groups. Individuals in the BAP group, even after controlling for age, education level, sex, and health problems, exhibited more real-world executive function problems in multiple domains, reported lower levels of social support, and self-rated increased depression and anxiety symptomatology compared to the control group. Regression analysis revealed that level of social support was the strongest predictor of BAP traits across both groups, although real-world executive function problems and depression symptomatology were also significant predictors. Moreover, when predicting anxiety and depression symptomatology, BAP traits were the strongest predictors above and beyond the effects of demographic factors, real-world executive function problems, and social support levels. These findings suggest that the BAP in older adulthood imparts additional risks to areas of functioning that are known to be crucial to aging-related outcomes in the context of typical development. These results might in turn inform aging in autism spectrum disorder, which has been largely unexplored to date. En ligne : http://dx.doi.org/10.1002/aur.1620 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2989 [article] Aging and autism spectrum disorder: Evidence from the broad autism phenotype [texte imprimé] / Gregory L. WALLACE, Auteur ; Jessica BUDGETT, Auteur ; Rebecca A. CHARLTON, Auteur . - p.1294-1303. Langues : Anglais (eng) in Autism Research > 9-12 (December 2016) . - p.1294-1303 Mots-clés : broad autism phenotype  autism  aging  older adulthood  executive function  anxiety  depression  social support Index. décimale : PER Périodiques Résumé : This study investigated for the first time the broad autism phenotype (BAP) in the context of older adulthood and its associations with real-world executive function, social support, and both depression and anxiety symptomatology. Based on self-ratings of autistic traits, 66 older adults (60+ years old, range?=?61–88) were split into BAP (n?=?20) and control (n?=?46) groups. Individuals in the BAP group, even after controlling for age, education level, sex, and health problems, exhibited more real-world executive function problems in multiple domains, reported lower levels of social support, and self-rated increased depression and anxiety symptomatology compared to the control group. Regression analysis revealed that level of social support was the strongest predictor of BAP traits across both groups, although real-world executive function problems and depression symptomatology were also significant predictors. Moreover, when predicting anxiety and depression symptomatology, BAP traits were the strongest predictors above and beyond the effects of demographic factors, real-world executive function problems, and social support levels. These findings suggest that the BAP in older adulthood imparts additional risks to areas of functioning that are known to be crucial to aging-related outcomes in the context of typical development. These results might in turn inform aging in autism spectrum disorder, which has been largely unexplored to date. En ligne : http://dx.doi.org/10.1002/aur.1620 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2989

Aging with elevated autistic traits: Cognitive functioning among older adults with the broad autism phenotype / Gavin R. STEWART in Research in Autism Spectrum Disorders, 54 (October 2018) 

Public ISBD [article]  in Research in Autism Spectrum Disorders > 54 (October 2018) . - p.27-36 Titre : Aging with elevated autistic traits: Cognitive functioning among older adults with the broad autism phenotype Type de document : texte imprimé Auteurs : Gavin R. STEWART, Auteur ; Rebecca A. CHARLTON, Auteur ; Gregory L. WALLACE, Auteur Article en page(s) : p.27-36 Langues : Anglais (eng) Mots-clés : Aging  Broad autism phenotype  Executive function Index. décimale : PER Périodiques Résumé : Background Little is known about the impact of aging with autism spectrum disorder (ASD) on cognition. As a first step in addressing this gap in our knowledge, the current study examined cognitive functioning among older adults with elevated, but subclinical levels of autistic traits (i.e., the Broad Autism Phenotype; BAP) compared to older adults without the BAP. Method Forty older adults (aged 60–91, M?=?73 years) were recruited and classified as meeting criteria for the BAP (n?=?20) or not (control older adults, COA; n?=?20). Different components of executive function as well as episodic memory were measured using standardized performance-based neuropsychological assessments in addition to a self-report questionnaire of executive function difficulties. Results Despite no differences in age, sex ratio, educational history or IQ, the BAP group demonstrated poorer performance on measures of executive function and episodic memory compared to the COA group. The BAP group also self-reported more executive function difficulties in everyday settings. Moreover, differences in working memory and attentional shifting were maintained after accounting for the influences of IQ and both depression and anxiety symptoms. Conclusions These findings suggest that aging with the BAP confers additional risk to cognitive function for older adults. As the BAP forms a bridge in the continuum from typical to atypical levels of autistic traits, these findings suggest that individuals with ASD might also incur cognitive costs as they age into older adulthood. En ligne : https://doi.org/10.1016/j.rasd.2018.06.009 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=3686 [article] Aging with elevated autistic traits: Cognitive functioning among older adults with the broad autism phenotype [texte imprimé] / Gavin R. STEWART, Auteur ; Rebecca A. CHARLTON, Auteur ; Gregory L. WALLACE, Auteur . - p.27-36. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 54 (October 2018) . - p.27-36 Mots-clés : Aging  Broad autism phenotype  Executive function Index. décimale : PER Périodiques Résumé : Background Little is known about the impact of aging with autism spectrum disorder (ASD) on cognition. As a first step in addressing this gap in our knowledge, the current study examined cognitive functioning among older adults with elevated, but subclinical levels of autistic traits (i.e., the Broad Autism Phenotype; BAP) compared to older adults without the BAP. Method Forty older adults (aged 60–91, M?=?73 years) were recruited and classified as meeting criteria for the BAP (n?=?20) or not (control older adults, COA; n?=?20). Different components of executive function as well as episodic memory were measured using standardized performance-based neuropsychological assessments in addition to a self-report questionnaire of executive function difficulties. Results Despite no differences in age, sex ratio, educational history or IQ, the BAP group demonstrated poorer performance on measures of executive function and episodic memory compared to the COA group. The BAP group also self-reported more executive function difficulties in everyday settings. Moreover, differences in working memory and attentional shifting were maintained after accounting for the influences of IQ and both depression and anxiety symptoms. Conclusions These findings suggest that aging with the BAP confers additional risk to cognitive function for older adults. As the BAP forms a bridge in the continuum from typical to atypical levels of autistic traits, these findings suggest that individuals with ASD might also incur cognitive costs as they age into older adulthood. En ligne : https://doi.org/10.1016/j.rasd.2018.06.009 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=3686

Attention deficit/hyperactivity disorder symptoms moderate cognition and behavior in children with autism spectrum disorders / Benjamin E. YERYS in Autism Research, 2-6 (December 2009) 

Public ISBD [article]  in Autism Research > 2-6 (December 2009) . - p.322-333 Titre : Attention deficit/hyperactivity disorder symptoms moderate cognition and behavior in children with autism spectrum disorders Type de document : texte imprimé Auteurs : Benjamin E. YERYS, Auteur ; Gregory L. WALLACE, Auteur ; Lauren E. KENWORTHY, Auteur ; Jennifer L. SOKOLOFF, Auteur ; Devon A. SHOOK, Auteur ; Joette D. JAMES, Auteur Article en page(s) : p.322-333 Langues : Anglais (eng) Mots-clés : clinical-psychology neuropsychology school-age Index. décimale : PER Périodiques Résumé : Recent estimates suggest that 31% of children with autism spectrum disorders (ASD) meet diagnostic criteria for attention deficit/hyperactivity disorder (ADHD), and another 24% of children with ASD exhibit subthreshold clinical ADHD symptoms. Presence of ADHD symptoms in the context of ASD could have a variety of effects on cognition, autistic traits, and adaptive/maladaptive behaviors including: exacerbating core ASD impairments; adding unique impairments specific to ADHD; producing new problems unreported in ASD or ADHD; having no clear impact; or producing some combination of these scenarios. Children with ASD and co-morbid ADHD symptoms (ASD+ADHD; n=21), children with ASD without ADHD (ASD; n=28), and a typically developing control group (n=21) were included in the study; all groups were matched on age, gender-ratio, IQ, and socioeconomic status. Data were collected on verbal and spatial working memory, response inhibition, global executive control (EC), autistic traits, adaptive functioning, and maladaptive behavior problems. In this sample, the presence of ADHD symptoms in ASD exacerbated impairments in EC and adaptive behavior and resulted in higher autistic trait, and externalizing behavior ratings. ADHD symptoms were also associated with greater impairments on a lab measure of verbal working memory. These findings suggest that children with ASD+ADHD symptoms present with exacerbated impairments in some but not all domains of functioning relative to children with ASD, most notably in adaptive behavior and working memory. Therefore, ADHD may moderate the expression of components of the ASD cognitive and behavioral phenotype, but ASD+ADHD may not represent an etiologically distinct phenotype from ASD alone. En ligne : http://dx.doi.org/10.1002/aur.103 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=9685 [article] Attention deficit/hyperactivity disorder symptoms moderate cognition and behavior in children with autism spectrum disorders [texte imprimé] / Benjamin E. YERYS, Auteur ; Gregory L. WALLACE, Auteur ; Lauren E. KENWORTHY, Auteur ; Jennifer L. SOKOLOFF, Auteur ; Devon A. SHOOK, Auteur ; Joette D. JAMES, Auteur . - p.322-333. Langues : Anglais (eng) in Autism Research > 2-6 (December 2009) . - p.322-333 Mots-clés : clinical-psychology neuropsychology school-age Index. décimale : PER Périodiques Résumé : Recent estimates suggest that 31% of children with autism spectrum disorders (ASD) meet diagnostic criteria for attention deficit/hyperactivity disorder (ADHD), and another 24% of children with ASD exhibit subthreshold clinical ADHD symptoms. Presence of ADHD symptoms in the context of ASD could have a variety of effects on cognition, autistic traits, and adaptive/maladaptive behaviors including: exacerbating core ASD impairments; adding unique impairments specific to ADHD; producing new problems unreported in ASD or ADHD; having no clear impact; or producing some combination of these scenarios. Children with ASD and co-morbid ADHD symptoms (ASD+ADHD; n=21), children with ASD without ADHD (ASD; n=28), and a typically developing control group (n=21) were included in the study; all groups were matched on age, gender-ratio, IQ, and socioeconomic status. Data were collected on verbal and spatial working memory, response inhibition, global executive control (EC), autistic traits, adaptive functioning, and maladaptive behavior problems. In this sample, the presence of ADHD symptoms in ASD exacerbated impairments in EC and adaptive behavior and resulted in higher autistic trait, and externalizing behavior ratings. ADHD symptoms were also associated with greater impairments on a lab measure of verbal working memory. These findings suggest that children with ASD+ADHD symptoms present with exacerbated impairments in some but not all domains of functioning relative to children with ASD, most notably in adaptive behavior and working memory. Therefore, ADHD may moderate the expression of components of the ASD cognitive and behavioral phenotype, but ASD+ADHD may not represent an etiologically distinct phenotype from ASD alone. En ligne : http://dx.doi.org/10.1002/aur.103 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=9685

Autism Risk Gene MET Variation and Cortical Thickness in Typically Developing Children and Adolescents / Alexis HEDRICK in Autism Research, 5-6 (December 2012) 

Public ISBD [article]  in Autism Research > 5-6 (December 2012) . - p.434-439 Titre : Autism Risk Gene MET Variation and Cortical Thickness in Typically Developing Children and Adolescents Type de document : texte imprimé Auteurs : Alexis HEDRICK, Auteur ; Yohan LEE, Auteur ; Gregory L. WALLACE, Auteur ; Deanna GREENSTEIN, Auteur ; Liv S. CLASEN, Auteur ; Jay N. GIEDD, Auteur ; Armin RAZNAHAN, Auteur Article en page(s) : p.434-439 Mots-clés : MET receptor tyrosine kinase  cortex  autism  development  MRI Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.1256 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1873 [article] Autism Risk Gene MET Variation and Cortical Thickness in Typically Developing Children and Adolescents [texte imprimé] / Alexis HEDRICK, Auteur ; Yohan LEE, Auteur ; Gregory L. WALLACE, Auteur ; Deanna GREENSTEIN, Auteur ; Liv S. CLASEN, Auteur ; Jay N. GIEDD, Auteur ; Armin RAZNAHAN, Auteur . - p.434-439. in Autism Research > 5-6 (December 2012) . - p.434-439 Mots-clés : MET receptor tyrosine kinase  cortex  autism  development  MRI Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.1256 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=1873

Brief Report: Further Evidence for Inner Speech Deficits in Autism Spectrum Disorders / Gregory L. WALLACE in Journal of Autism and Developmental Disorders, 39-12 (December 2009) 

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Brief Report: Information Processing Speed is Intact in Autism but not Correlated with Measured Intelligence / Gregory L. WALLACE in Journal of Autism and Developmental Disorders, 39-5 (May 2009) 

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Brief Report: IQ Split Predicts Social Symptoms and Communication Abilities in High-Functioning Children with Autism Spectrum Disorders / David O. BLACK in Journal of Autism and Developmental Disorders, 39-11 (November 2009) 

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Characterizing the Factor Structure of Parent Reported Executive Function in Autism Spectrum Disorders: The Impact of Cognitive Inflexibility / Yael GRANADER in Journal of Autism and Developmental Disorders, 44-12 (December 2014) 

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Depression and anxiety symptoms in children and adolescents with autism spectrum disorders without intellectual disability / John F. STRANG in Research in Autism Spectrum Disorders, 6-1 (January-March 2012) 

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Diminished Sensitivity to Sad Facial Expressions in High Functioning Autism Spectrum Disorders is Associated with Symptomatology and Adaptive Functioning / Gregory L. WALLACE in Journal of Autism and Developmental Disorders, 41-11 (November 2011) 

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Divergence of Age-Related Differences in Social-Communication: Improvements for Typically Developing Youth but Declines for Youth with Autism Spectrum Disorder / Gregory L. WALLACE in Journal of Autism and Developmental Disorders, 47-2 (February 2017) 

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Do social attribution skills improve with age in children with high functioning autism spectrum disorders? / Elgiz BAL in Research in Autism Spectrum Disorders, 7-1 (January 2013) 

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Dosage effects of X and Y chromosomes on language and social functioning in children with supernumerary sex chromosome aneuploidies: implications for idiopathic language impairment and autism spectrum disorders / Nancy RAITANO LEE in Journal of Child Psychology and Psychiatry, 53-10 (October 2012) 

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Early language milestones predict later language, but not autism symptoms in higher functioning children with autism spectrum disorders / Lauren E. KENWORTHY in Research in Autism Spectrum Disorders, 6-3 (July-September 2012) 

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