Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Résultat de la recherche
5 recherche sur le mot-clé 'Asperger disorder'
Affiner la recherche Générer le flux rss de la recherche
Partager le résultat de cette recherche Faire une suggestion
A cluster analysis exploration of autism spectrum disorder subgroups in children without intellectual disability / Felicity KLOPPER in Research in Autism Spectrum Disorders, 36 (April 2017)
[article]
Titre : A cluster analysis exploration of autism spectrum disorder subgroups in children without intellectual disability Type de document : Texte imprimé et/ou numérique Auteurs : Felicity KLOPPER, Auteur ; Renee TESTA, Auteur ; Christos PANTELIS, Auteur ; Efstratios SKAFIDAS, Auteur Article en page(s) : p.66-78 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders Asperger disorder Autistic disorder Classification Subgroups Index. décimale : PER Périodiques Résumé : The heterogeneity in autism spectrum disorder (ASD) remains poorly understood, particularly in individuals without intellectual disability (ID), where phenotypic variability can be most pronounced. The presence of phenotypic subgroups continues to be questioned. This study investigated whether children with ASD without ID are differentiable into clinically meaningful subgroups. Method Data from the ‘gold standard’ ASD diagnostic instruments for 61 children (5–14 years) with ASD without ID were subjected to exploratory cluster analysis. Cognition, language, pragmatic communication, and behaviour were used to explore subgroups. Results Children with ASD without ID could be differentiated into Moderate and Severe Social Impairment subgroups when core ASD symptoms were more closely examined. The Moderate Social Impairment subgroup showed less severe social interaction and communication impairments but greater lifetime severity of restricted/repetitive behaviours. In contrast, the Severe Social Impairment subgroup, with poorer social interaction and communication skills, had lower lifetime severity of restricted/repetitive behaviours. This subgroup also had greater cognitive and language difficulties, and poorer adaptive functioning. Importantly, however, these neurocognitive and functional differences showed only small to moderate associations with the differentiated ASD clinical profiles. Conclusions Evidence of dissociated levels of severity across core ASD dimensions supports the idea that clinically meaningful subgroups within ASD without ID can be identified. The dissociated profiles of ASD features could represent different underlying neurobiological mechanisms for each subgroup. Identifying such subgroups in practice can improve the clinical utility of diagnostic labels in this population. Thus, both categorical and dimensional approaches may be useful in classifying ASD, with neither alone being adequate. En ligne : http://dx.doi.org/10.1016/j.rasd.2017.01.006 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=304
in Research in Autism Spectrum Disorders > 36 (April 2017) . - p.66-78[article] A cluster analysis exploration of autism spectrum disorder subgroups in children without intellectual disability [Texte imprimé et/ou numérique] / Felicity KLOPPER, Auteur ; Renee TESTA, Auteur ; Christos PANTELIS, Auteur ; Efstratios SKAFIDAS, Auteur . - p.66-78.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 36 (April 2017) . - p.66-78
Mots-clés : Autism spectrum disorders Asperger disorder Autistic disorder Classification Subgroups Index. décimale : PER Périodiques Résumé : The heterogeneity in autism spectrum disorder (ASD) remains poorly understood, particularly in individuals without intellectual disability (ID), where phenotypic variability can be most pronounced. The presence of phenotypic subgroups continues to be questioned. This study investigated whether children with ASD without ID are differentiable into clinically meaningful subgroups. Method Data from the ‘gold standard’ ASD diagnostic instruments for 61 children (5–14 years) with ASD without ID were subjected to exploratory cluster analysis. Cognition, language, pragmatic communication, and behaviour were used to explore subgroups. Results Children with ASD without ID could be differentiated into Moderate and Severe Social Impairment subgroups when core ASD symptoms were more closely examined. The Moderate Social Impairment subgroup showed less severe social interaction and communication impairments but greater lifetime severity of restricted/repetitive behaviours. In contrast, the Severe Social Impairment subgroup, with poorer social interaction and communication skills, had lower lifetime severity of restricted/repetitive behaviours. This subgroup also had greater cognitive and language difficulties, and poorer adaptive functioning. Importantly, however, these neurocognitive and functional differences showed only small to moderate associations with the differentiated ASD clinical profiles. Conclusions Evidence of dissociated levels of severity across core ASD dimensions supports the idea that clinically meaningful subgroups within ASD without ID can be identified. The dissociated profiles of ASD features could represent different underlying neurobiological mechanisms for each subgroup. Identifying such subgroups in practice can improve the clinical utility of diagnostic labels in this population. Thus, both categorical and dimensional approaches may be useful in classifying ASD, with neither alone being adequate. En ligne : http://dx.doi.org/10.1016/j.rasd.2017.01.006 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=304 Annual Research Review: Looking back to look forward - changes in the concept of autism and implications for future research / Francesca HAPPE in Journal of Child Psychology and Psychiatry, 61-3 (March 2020)
[article]
Titre : Annual Research Review: Looking back to look forward - changes in the concept of autism and implications for future research Type de document : Texte imprimé et/ou numérique Auteurs : Francesca HAPPE, Auteur ; Uta FRITH, Auteur Article en page(s) : p.218-232 Langues : Anglais (eng) Mots-clés : Asperger disorder Autism spectrum disorders neurodevelopmental disorders social cognition Index. décimale : PER Périodiques Résumé : The concept of autism is a significant contribution from child psychiatry that has entered wider culture and public consciousness, and has evolved significantly over the last four decades. Taking a rather personal retrospective, reflecting on our own time in autism research, this review explores changes in the concept of autism and the implications of these for future research. We focus on seven major changes in how autism is thought of, operationalised, and recognised: (1) from a narrow definition to wide diagnostic criteria; (2) from a rare to a relatively common condition, although probably still under-recognised in women; (3) from something affecting children, to a lifelong condition; (4) from something discreet and distinct, to a dimensional view; (5) from one thing to many 'autisms', and a compound or 'fractionable' condition; (6) from a focus on 'pure' autism, to recognition that complexity and comorbidity is the norm; and finally, (7) from conceptualising autism purely as a 'developmental disorder', to recognising a neurodiversity perspective, operationalised in participatory research models. We conclude with some challenges for the field and suggestions for areas currently neglected in autism research. En ligne : http://dx.doi.org/10.1111/jcpp.13176 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420
in Journal of Child Psychology and Psychiatry > 61-3 (March 2020) . - p.218-232[article] Annual Research Review: Looking back to look forward - changes in the concept of autism and implications for future research [Texte imprimé et/ou numérique] / Francesca HAPPE, Auteur ; Uta FRITH, Auteur . - p.218-232.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-3 (March 2020) . - p.218-232
Mots-clés : Asperger disorder Autism spectrum disorders neurodevelopmental disorders social cognition Index. décimale : PER Périodiques Résumé : The concept of autism is a significant contribution from child psychiatry that has entered wider culture and public consciousness, and has evolved significantly over the last four decades. Taking a rather personal retrospective, reflecting on our own time in autism research, this review explores changes in the concept of autism and the implications of these for future research. We focus on seven major changes in how autism is thought of, operationalised, and recognised: (1) from a narrow definition to wide diagnostic criteria; (2) from a rare to a relatively common condition, although probably still under-recognised in women; (3) from something affecting children, to a lifelong condition; (4) from something discreet and distinct, to a dimensional view; (5) from one thing to many 'autisms', and a compound or 'fractionable' condition; (6) from a focus on 'pure' autism, to recognition that complexity and comorbidity is the norm; and finally, (7) from conceptualising autism purely as a 'developmental disorder', to recognising a neurodiversity perspective, operationalised in participatory research models. We conclude with some challenges for the field and suggestions for areas currently neglected in autism research. En ligne : http://dx.doi.org/10.1111/jcpp.13176 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420 Group cognitive behavioural therapy and group recreational activity for adults with autism spectrum disorders: A preliminary randomized controlled trial / Eva HESSELMARK in Autism, 18-6 (August 2014)
[article]
Titre : Group cognitive behavioural therapy and group recreational activity for adults with autism spectrum disorders: A preliminary randomized controlled trial Type de document : Texte imprimé et/ou numérique Auteurs : Eva HESSELMARK, Auteur ; Stephanie PLENTY, Auteur ; Susanne BEJEROT, Auteur Article en page(s) : p.672-683 Langues : Anglais (eng) Mots-clés : adult Asperger disorder autism cognitive behaviour therapy group randomized controlled trial Index. décimale : PER Périodiques Résumé : Although adults with autism spectrum disorder are an increasingly identified patient population, few treatment options are available. This preliminary randomized controlled open trial with a parallel design developed two group interventions for adults with autism spectrum disorders and intelligence within the normal range: cognitive behavioural therapy and recreational activity. Both interventions comprised 36 weekly 3-h sessions led by two therapists in groups of 6–8 patients. A total of 68 psychiatric patients with autism spectrum disorders participated in the study. Outcome measures were Quality of Life Inventory, Sense of Coherence Scale, Rosenberg Self-Esteem Scale and an exploratory analysis on measures of psychiatric health. Participants in both treatment conditions reported an increased quality of life at post-treatment (d = 0.39, p 0.001), with no difference between interventions. No amelioration of psychiatric symptoms was observed. The dropout rate was lower with cognitive behavioural therapy than with recreational activity, and participants in cognitive behavioural therapy rated themselves as more generally improved, as well as more improved regarding expression of needs and understanding of difficulties. Both interventions appear to be promising treatment options for adults with autism spectrum disorder. The interventions’ similar efficacy may be due to the common elements, structure and group setting. Cognitive behavioural therapy may be additionally beneficial in terms of increasing specific skills and minimizing dropout. En ligne : http://dx.doi.org/10.1177/1362361313493681 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=237
in Autism > 18-6 (August 2014) . - p.672-683[article] Group cognitive behavioural therapy and group recreational activity for adults with autism spectrum disorders: A preliminary randomized controlled trial [Texte imprimé et/ou numérique] / Eva HESSELMARK, Auteur ; Stephanie PLENTY, Auteur ; Susanne BEJEROT, Auteur . - p.672-683.
Langues : Anglais (eng)
in Autism > 18-6 (August 2014) . - p.672-683
Mots-clés : adult Asperger disorder autism cognitive behaviour therapy group randomized controlled trial Index. décimale : PER Périodiques Résumé : Although adults with autism spectrum disorder are an increasingly identified patient population, few treatment options are available. This preliminary randomized controlled open trial with a parallel design developed two group interventions for adults with autism spectrum disorders and intelligence within the normal range: cognitive behavioural therapy and recreational activity. Both interventions comprised 36 weekly 3-h sessions led by two therapists in groups of 6–8 patients. A total of 68 psychiatric patients with autism spectrum disorders participated in the study. Outcome measures were Quality of Life Inventory, Sense of Coherence Scale, Rosenberg Self-Esteem Scale and an exploratory analysis on measures of psychiatric health. Participants in both treatment conditions reported an increased quality of life at post-treatment (d = 0.39, p 0.001), with no difference between interventions. No amelioration of psychiatric symptoms was observed. The dropout rate was lower with cognitive behavioural therapy than with recreational activity, and participants in cognitive behavioural therapy rated themselves as more generally improved, as well as more improved regarding expression of needs and understanding of difficulties. Both interventions appear to be promising treatment options for adults with autism spectrum disorder. The interventions’ similar efficacy may be due to the common elements, structure and group setting. Cognitive behavioural therapy may be additionally beneficial in terms of increasing specific skills and minimizing dropout. En ligne : http://dx.doi.org/10.1177/1362361313493681 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=237 Health-related quality of life in children with high-functioning autism / Marie-Christine POTVIN in Autism, 19-1 (January 2015)
[article]
Titre : Health-related quality of life in children with high-functioning autism Type de document : Texte imprimé et/ou numérique Auteurs : Marie-Christine POTVIN, Auteur ; Laurie SNIDER, Auteur ; Patricia A. PRELOCK, Auteur ; Sharon WOOD-DAUPHINEE, Auteur ; Eva KEHAYIA, Auteur Année de publication : 2015 Article en page(s) : p.14-19 Langues : Anglais (eng) Mots-clés : Asperger disorder autism autistic disorder health-related quality of life pervasive developmental disorder; Index. décimale : PER Périodiques Résumé : The health-related quality of life of school-aged children with high-functioning autism is poorly understood. The objectives of this study were to compare the health-related quality of life of children with high-functioning autism to that of typically developing peers and to compare child-self and parent-proxy reports of health-related quality of life of children. A cross-sectional study of children with high-functioning autism (n = 30) and peers (n = 31) was conducted using the Pediatric Quality of Life Inventory 4.0 Generic Core Scales. Children with high-functioning autism had significantly poorer health-related quality of life than peers whether reported by themselves (p < .001) or their parents (p < .001), although disagreement (intra-class coefficient = ?.075) between children and parental scores suggested variance in points of view. This study specifically investigated health-related quality of life in children with high-functioning autism as compared to a sample of peers, from the child’s perspective. It strengthens earlier findings that children with high-functioning autism experience poorer health-related quality of life than those without this disorder and points to the importance of clinicians working with families to identify areas in a child’s life that promote or hinder their sense of well-being. En ligne : http://dx.doi.org/10.1177/1362361313509730 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=245
in Autism > 19-1 (January 2015) . - p.14-19[article] Health-related quality of life in children with high-functioning autism [Texte imprimé et/ou numérique] / Marie-Christine POTVIN, Auteur ; Laurie SNIDER, Auteur ; Patricia A. PRELOCK, Auteur ; Sharon WOOD-DAUPHINEE, Auteur ; Eva KEHAYIA, Auteur . - 2015 . - p.14-19.
Langues : Anglais (eng)
in Autism > 19-1 (January 2015) . - p.14-19
Mots-clés : Asperger disorder autism autistic disorder health-related quality of life pervasive developmental disorder; Index. décimale : PER Périodiques Résumé : The health-related quality of life of school-aged children with high-functioning autism is poorly understood. The objectives of this study were to compare the health-related quality of life of children with high-functioning autism to that of typically developing peers and to compare child-self and parent-proxy reports of health-related quality of life of children. A cross-sectional study of children with high-functioning autism (n = 30) and peers (n = 31) was conducted using the Pediatric Quality of Life Inventory 4.0 Generic Core Scales. Children with high-functioning autism had significantly poorer health-related quality of life than peers whether reported by themselves (p < .001) or their parents (p < .001), although disagreement (intra-class coefficient = ?.075) between children and parental scores suggested variance in points of view. This study specifically investigated health-related quality of life in children with high-functioning autism as compared to a sample of peers, from the child’s perspective. It strengthens earlier findings that children with high-functioning autism experience poorer health-related quality of life than those without this disorder and points to the importance of clinicians working with families to identify areas in a child’s life that promote or hinder their sense of well-being. En ligne : http://dx.doi.org/10.1177/1362361313509730 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=245 Recreational Participation of Children with High Functioning Autism / Marie-Christine POTVIN in Journal of Autism and Developmental Disorders, 43-2 (February 2013)
[article]
Titre : Recreational Participation of Children with High Functioning Autism Type de document : Texte imprimé et/ou numérique Auteurs : Marie-Christine POTVIN, Auteur ; Laurie SNIDER, Auteur ; Patricia A. PRELOCK, Auteur ; Eva KEHAYIA, Auteur ; Sharon WOOD-DAUPHINEE, Auteur Article en page(s) : p.445-457 Langues : (Eng) Mots-clés : Recreation Leisure Autism Autistic disorder Asperger disorder Pervasive developmental disorder Index. décimale : PER Périodiques Résumé : The recreation of children with High Functioning Autism (HFA) is not well understood. The objective of this cross-sectional study was to compare the recreational engagement of children with HFA and their typically developing peers. Children with HFA (n = 30) and peers (n = 31) were similar on key characteristics that may impact recreation except those related to the HFA attributes. Children with HFA differed from peers in terms of diversity (p = .002), social aspects (p = .006) and locations (p .001) of recreation. The two groups were not statistically different in personal intensity (p = .684), enjoyment (p = .239) or preferences (p = .788) of recreation. A recreational profile was developed to benefit parents and clinicians in supporting the recreation of these children. En ligne : http://dx.doi.org/10.1007/s10803-012-1589-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=188
in Journal of Autism and Developmental Disorders > 43-2 (February 2013) . - p.445-457[article] Recreational Participation of Children with High Functioning Autism [Texte imprimé et/ou numérique] / Marie-Christine POTVIN, Auteur ; Laurie SNIDER, Auteur ; Patricia A. PRELOCK, Auteur ; Eva KEHAYIA, Auteur ; Sharon WOOD-DAUPHINEE, Auteur . - p.445-457.
Langues : (Eng)
in Journal of Autism and Developmental Disorders > 43-2 (February 2013) . - p.445-457
Mots-clés : Recreation Leisure Autism Autistic disorder Asperger disorder Pervasive developmental disorder Index. décimale : PER Périodiques Résumé : The recreation of children with High Functioning Autism (HFA) is not well understood. The objective of this cross-sectional study was to compare the recreational engagement of children with HFA and their typically developing peers. Children with HFA (n = 30) and peers (n = 31) were similar on key characteristics that may impact recreation except those related to the HFA attributes. Children with HFA differed from peers in terms of diversity (p = .002), social aspects (p = .006) and locations (p .001) of recreation. The two groups were not statistically different in personal intensity (p = .684), enjoyment (p = .239) or preferences (p = .788) of recreation. A recreational profile was developed to benefit parents and clinicians in supporting the recreation of these children. En ligne : http://dx.doi.org/10.1007/s10803-012-1589-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=188