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Détail de l'auteur
Auteur David A. BRENT |
Documents disponibles écrits par cet auteur (15)



Adolescent suicide and suicidal behavior / Jeffrey A. BRIDGE in Journal of Child Psychology and Psychiatry, 47-3/4 (March/April 2006)
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Titre : Adolescent suicide and suicidal behavior Type de document : Texte imprimé et/ou numérique Auteurs : Jeffrey A. BRIDGE, Auteur ; Tina R. GOLDSTEIN, Auteur ; David A. BRENT, Auteur Année de publication : 2006 Article en page(s) : p.372–394 Langues : Anglais (eng) Mots-clés : Suicide children adolescents suicidal-behavior risk-factors Index. décimale : PER Périodiques Résumé : This review examines the descriptive epidemiology, and risk and protective factors for youth suicide and suicidal behavior. A model of youth suicidal behavior is articulated, whereby suicidal behavior ensues as a result of an interaction of socio-cultural, developmental, psychiatric, psychological, and family-environmental factors. On the basis of this review, clinical and public health approaches to the reduction in youth suicide and recommendations for further research will be discussed. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01615.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=726
in Journal of Child Psychology and Psychiatry > 47-3/4 (March/April 2006) . - p.372–394[article] Adolescent suicide and suicidal behavior [Texte imprimé et/ou numérique] / Jeffrey A. BRIDGE, Auteur ; Tina R. GOLDSTEIN, Auteur ; David A. BRENT, Auteur . - 2006 . - p.372–394.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 47-3/4 (March/April 2006) . - p.372–394
Mots-clés : Suicide children adolescents suicidal-behavior risk-factors Index. décimale : PER Périodiques Résumé : This review examines the descriptive epidemiology, and risk and protective factors for youth suicide and suicidal behavior. A model of youth suicidal behavior is articulated, whereby suicidal behavior ensues as a result of an interaction of socio-cultural, developmental, psychiatric, psychological, and family-environmental factors. On the basis of this review, clinical and public health approaches to the reduction in youth suicide and recommendations for further research will be discussed. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01615.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=726 Annual Research Review: Defining and treating pediatric treatment-resistant depression / Jennifer B. DWYER in Journal of Child Psychology and Psychiatry, 61-3 (March 2020)
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Titre : Annual Research Review: Defining and treating pediatric treatment-resistant depression Type de document : Texte imprimé et/ou numérique Auteurs : Jennifer B. DWYER, Auteur ; Argyris STRINGARIS, Auteur ; David A. BRENT, Auteur ; Michael H. BLOCH, Auteur Article en page(s) : p.312-332 Langues : Anglais (eng) Mots-clés : Depression major depressive disorder psychopharmacology psychotherapy Index. décimale : PER Périodiques Résumé : BACKGROUND: Adolescent major depressive disorder (MDD) is a significant health problem, associated with substantial morbidity, cost, and mortality. Depression is a significant risk factor for suicide, which is now the second leading cause of death in young people. Up to twenty per cent of adolescents will experience MDD before adulthood, and while a substantial proportion will improve with standard-of-care treatments (psychotherapy and medication), roughly one third will not. METHODS: Here, we have reviewed the literature in order to discuss the concept of treatment-resistant depression (TRD) in adolescence, examine risk factors, diagnostic difficulties, and challenges in evaluating symptom improvement, and providing guidance on how to define adequate medication and psychotherapy treatment trials. RESULTS: We propose a staging model for adolescent TRD and review the treatment literature. The evidence base for first- and second-line treatments primarily derives from four large pediatric clinical trials (TADS, TORDIA, ADAPT, and IMPACT). After two medications and a trial of evidence-based psychotherapy have failed to alleviate depressive symptoms, the evidence becomes quite thin for subsequent treatments. Here, we review the evidence for the effectiveness of medication switches, medication augmentation, psychotherapy augmentation, and interventional treatments (i.e., transcranial magnetic stimulation, electroconvulsive therapy, and ketamine) for adolescent TRD. Comparisons are drawn to the adult TRD literature, and areas for future pediatric depression research are highlighted. CONCLUSIONS: As evidence is limited for treatments in this population, a careful consideration of the known risks and side effects of escalated treatments (e.g., mood stabilizers and atypical antipsychotics) is warranted and weighed against potential, but often untested, benefits. En ligne : http://dx.doi.org/10.1111/jcpp.13202 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420
in Journal of Child Psychology and Psychiatry > 61-3 (March 2020) . - p.312-332[article] Annual Research Review: Defining and treating pediatric treatment-resistant depression [Texte imprimé et/ou numérique] / Jennifer B. DWYER, Auteur ; Argyris STRINGARIS, Auteur ; David A. BRENT, Auteur ; Michael H. BLOCH, Auteur . - p.312-332.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-3 (March 2020) . - p.312-332
Mots-clés : Depression major depressive disorder psychopharmacology psychotherapy Index. décimale : PER Périodiques Résumé : BACKGROUND: Adolescent major depressive disorder (MDD) is a significant health problem, associated with substantial morbidity, cost, and mortality. Depression is a significant risk factor for suicide, which is now the second leading cause of death in young people. Up to twenty per cent of adolescents will experience MDD before adulthood, and while a substantial proportion will improve with standard-of-care treatments (psychotherapy and medication), roughly one third will not. METHODS: Here, we have reviewed the literature in order to discuss the concept of treatment-resistant depression (TRD) in adolescence, examine risk factors, diagnostic difficulties, and challenges in evaluating symptom improvement, and providing guidance on how to define adequate medication and psychotherapy treatment trials. RESULTS: We propose a staging model for adolescent TRD and review the treatment literature. The evidence base for first- and second-line treatments primarily derives from four large pediatric clinical trials (TADS, TORDIA, ADAPT, and IMPACT). After two medications and a trial of evidence-based psychotherapy have failed to alleviate depressive symptoms, the evidence becomes quite thin for subsequent treatments. Here, we review the evidence for the effectiveness of medication switches, medication augmentation, psychotherapy augmentation, and interventional treatments (i.e., transcranial magnetic stimulation, electroconvulsive therapy, and ketamine) for adolescent TRD. Comparisons are drawn to the adult TRD literature, and areas for future pediatric depression research are highlighted. CONCLUSIONS: As evidence is limited for treatments in this population, a careful consideration of the known risks and side effects of escalated treatments (e.g., mood stabilizers and atypical antipsychotics) is warranted and weighed against potential, but often untested, benefits. En ligne : http://dx.doi.org/10.1111/jcpp.13202 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420 Childhood maltreatment, neuropsychological function and suicidal behavior / J. ZELAZNY in Journal of Child Psychology and Psychiatry, 60-10 (October 2019)
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Titre : Childhood maltreatment, neuropsychological function and suicidal behavior Type de document : Texte imprimé et/ou numérique Auteurs : J. ZELAZNY, Auteur ; N. MELHEM, Auteur ; G. PORTA, Auteur ; C. BIERNESSER, Auteur ; J. G. KEILP, Auteur ; J. J. MANN, Auteur ; M. A. OQUENDO, Auteur ; B. STANLEY, Auteur ; David A. BRENT, Auteur Article en page(s) : p.1085-1093 Langues : Anglais (eng) Mots-clés : Maltreatment depression executive function suicidal behavior Index. décimale : PER Périodiques Résumé : BACKGROUND: Suicide is the second leading cause of death in young people. Childhood maltreatment, neuropsychological dysfunction and psychopathology have each been shown to increase risk for suicidal behavior. However, few studies have examined their interactions and the effects of those interactions on suicidal behavior. METHODS: Across two sites, a total of 382 offspring of depressed parents underwent neuropsychological assessments. This high-risk sample included nearly equal numbers of males and females. Average age at the time of neuropsychological assessment was 18.5 years. The most prevalent lifetime psychiatric disorders were mood (43%), anxiety (37%) and alcohol and substance use disorders (21%). Childhood maltreatment was reported by 44% of offspring. Participants underwent extensive neuropsychological testing assessing the following domains: attention, memory, executive function, working memory, language fluency, and impulse control. Logistic regression was used to examine the association of reported childhood maltreatment, neuropsychological functioning, psychopathology and their interactions with suicidal behavior. Bonferroni correction was used to adjust for multiple comparisons. RESULTS: Maltreatment was associated with increased risk of suicidal behavior with odds ratios ranging between 2.40 and 4.43. Moderation analyses found that adaptive neuropsychological functioning was not protective against childhood maltreatment's effect on suicidal risk. While lifetime history of mood disorder was strongly associated with suicidal behavior, higher scores in working memory (OR = 0.21; 95% CI = 0.09, 0.45; p < .001) and executive function (OR = 0.15; 95% CI = 0.05, 0.43; p < .001) were protective against suicidal behavior even in the presence of a lifetime history of mood disorder. CONCLUSIONS: Further research is needed to determine how neuropsychological capacity protects depressed patients against the risk of suicidal behavior. En ligne : http://dx.doi.org/10.1111/jcpp.13096 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=406
in Journal of Child Psychology and Psychiatry > 60-10 (October 2019) . - p.1085-1093[article] Childhood maltreatment, neuropsychological function and suicidal behavior [Texte imprimé et/ou numérique] / J. ZELAZNY, Auteur ; N. MELHEM, Auteur ; G. PORTA, Auteur ; C. BIERNESSER, Auteur ; J. G. KEILP, Auteur ; J. J. MANN, Auteur ; M. A. OQUENDO, Auteur ; B. STANLEY, Auteur ; David A. BRENT, Auteur . - p.1085-1093.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 60-10 (October 2019) . - p.1085-1093
Mots-clés : Maltreatment depression executive function suicidal behavior Index. décimale : PER Périodiques Résumé : BACKGROUND: Suicide is the second leading cause of death in young people. Childhood maltreatment, neuropsychological dysfunction and psychopathology have each been shown to increase risk for suicidal behavior. However, few studies have examined their interactions and the effects of those interactions on suicidal behavior. METHODS: Across two sites, a total of 382 offspring of depressed parents underwent neuropsychological assessments. This high-risk sample included nearly equal numbers of males and females. Average age at the time of neuropsychological assessment was 18.5 years. The most prevalent lifetime psychiatric disorders were mood (43%), anxiety (37%) and alcohol and substance use disorders (21%). Childhood maltreatment was reported by 44% of offspring. Participants underwent extensive neuropsychological testing assessing the following domains: attention, memory, executive function, working memory, language fluency, and impulse control. Logistic regression was used to examine the association of reported childhood maltreatment, neuropsychological functioning, psychopathology and their interactions with suicidal behavior. Bonferroni correction was used to adjust for multiple comparisons. RESULTS: Maltreatment was associated with increased risk of suicidal behavior with odds ratios ranging between 2.40 and 4.43. Moderation analyses found that adaptive neuropsychological functioning was not protective against childhood maltreatment's effect on suicidal risk. While lifetime history of mood disorder was strongly associated with suicidal behavior, higher scores in working memory (OR = 0.21; 95% CI = 0.09, 0.45; p < .001) and executive function (OR = 0.15; 95% CI = 0.05, 0.43; p < .001) were protective against suicidal behavior even in the presence of a lifetime history of mood disorder. CONCLUSIONS: Further research is needed to determine how neuropsychological capacity protects depressed patients against the risk of suicidal behavior. En ligne : http://dx.doi.org/10.1111/jcpp.13096 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=406 Commentary: Reducing adolescent suicide: a global imperative - a reflection on Glenn et al. (2020) / David A. BRENT in Journal of Child Psychology and Psychiatry, 61-3 (March 2020)
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Titre : Commentary: Reducing adolescent suicide: a global imperative - a reflection on Glenn et al. (2020) Type de document : Texte imprimé et/ou numérique Auteurs : David A. BRENT, Auteur Article en page(s) : p.309-311 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Glenn and colleagues have examined rates of adolescent suicide across 45 countries and explored the role of sex, age, rurality and availability of guns and railways on suicide rates. Higher rates of adolescent suicide in New Zealand may be explained by the very high rate of adolescent suicide in young Maoris. Future work could be enhanced by reporting on national trends in suicide, reporting on rates broken down by race and ethnicity, and through the development of international psychological autopsy studies that could shed light on cross-country differences. While this article found that income inequality was correlated with the male-to-female ratio of adolescent suicide across countries, the opposite trend has been reported in the United States. However, as noted by this article, the effects of poverty matter. The Move To Opportunity study found that when youth under the age of 13 were moved from a high poverty to a low poverty neighbourhood, there were enduring effects, including lower levels of depression and anxiety. While adolescent suicide is a global concern, reduction in the suicide rate may have local solutions, including those that address the pernicious effects of poverty and poor neighbourhoods on youth. En ligne : http://dx.doi.org/10.1111/jcpp.13174 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420
in Journal of Child Psychology and Psychiatry > 61-3 (March 2020) . - p.309-311[article] Commentary: Reducing adolescent suicide: a global imperative - a reflection on Glenn et al. (2020) [Texte imprimé et/ou numérique] / David A. BRENT, Auteur . - p.309-311.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-3 (March 2020) . - p.309-311
Index. décimale : PER Périodiques Résumé : Glenn and colleagues have examined rates of adolescent suicide across 45 countries and explored the role of sex, age, rurality and availability of guns and railways on suicide rates. Higher rates of adolescent suicide in New Zealand may be explained by the very high rate of adolescent suicide in young Maoris. Future work could be enhanced by reporting on national trends in suicide, reporting on rates broken down by race and ethnicity, and through the development of international psychological autopsy studies that could shed light on cross-country differences. While this article found that income inequality was correlated with the male-to-female ratio of adolescent suicide across countries, the opposite trend has been reported in the United States. However, as noted by this article, the effects of poverty matter. The Move To Opportunity study found that when youth under the age of 13 were moved from a high poverty to a low poverty neighbourhood, there were enduring effects, including lower levels of depression and anxiety. While adolescent suicide is a global concern, reduction in the suicide rate may have local solutions, including those that address the pernicious effects of poverty and poor neighbourhoods on youth. En ligne : http://dx.doi.org/10.1111/jcpp.13174 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420 Commentary: The course of depression after childhood parental death – a reflection on Berg et al. (2016) / Nadine M. MELHEM in Journal of Child Psychology and Psychiatry, 57-12 (December 2016)
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Titre : Commentary: The course of depression after childhood parental death – a reflection on Berg et al. (2016) Type de document : Texte imprimé et/ou numérique Auteurs : Nadine M. MELHEM, Auteur ; David A. BRENT, Auteur Article en page(s) : p.1467-1469 Langues : Anglais (eng) Mots-clés : Depression death Index. décimale : PER Périodiques Résumé : Berg et al.'s study highlights the long-lasting impact of childhood parental death on depression in adulthood in the absence of early preventive and intervention efforts. Given the long-term effects of childhood parental death, it seems that the most propitious time to intervene is early on after the death. Several prevention and intervention approaches have been shown to reduce the incidence of depression and to ameliorate its course and thus could be potential approaches to intervene with parentally bereaved children. Future longitudinal studies focused on children and adolescents are also needed to examine the biological pathways that set the stage for increased vulnerability across the life span following childhood parental death and adversity in order to inform novel targets for interventions. En ligne : http://dx.doi.org/10.1111/jcpp.12626 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298
in Journal of Child Psychology and Psychiatry > 57-12 (December 2016) . - p.1467-1469[article] Commentary: The course of depression after childhood parental death – a reflection on Berg et al. (2016) [Texte imprimé et/ou numérique] / Nadine M. MELHEM, Auteur ; David A. BRENT, Auteur . - p.1467-1469.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 57-12 (December 2016) . - p.1467-1469
Mots-clés : Depression death Index. décimale : PER Périodiques Résumé : Berg et al.'s study highlights the long-lasting impact of childhood parental death on depression in adulthood in the absence of early preventive and intervention efforts. Given the long-term effects of childhood parental death, it seems that the most propitious time to intervene is early on after the death. Several prevention and intervention approaches have been shown to reduce the incidence of depression and to ameliorate its course and thus could be potential approaches to intervene with parentally bereaved children. Future longitudinal studies focused on children and adolescents are also needed to examine the biological pathways that set the stage for increased vulnerability across the life span following childhood parental death and adversity in order to inform novel targets for interventions. En ligne : http://dx.doi.org/10.1111/jcpp.12626 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298 Commentary: A time to reap and a time to sow: reducing the adolescent suicide rate now and in the future: commentary on Cha et al. (2018) / David A. BRENT in Journal of Child Psychology and Psychiatry, 59-4 (April 2018)
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PermalinkCriterion validity of the Mood and Feelings Questionnaire for depressive episodes in clinic and non-clinic subjects / William BURLESON DAVISS in Journal of Child Psychology and Psychiatry, 47-9 (September 2006)
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PermalinkDimensional psychopathology in preschool offspring of parents with bipolar disorder / Hagai MAOZ in Journal of Child Psychology and Psychiatry, 55-2 (February 2014)
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PermalinkEarly indicators of response to transdiagnostic treatment of pediatric anxiety and depression / Michelle ROZENMAN ; Araceli GONZALEZ ; David A. BRENT ; Giovanna PORTA ; Frances L. LYNCH ; John F. DICKERSON ; V. Robin WEERSING in Journal of Child Psychology and Psychiatry, 64-12 (December 2023)
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PermalinkPediatric depression: is there evidence to improve evidence-based treatments? / David A. BRENT in Journal of Child Psychology and Psychiatry, 50-1-2 (January/February 2009)
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PermalinkPositive and negative social media experiences and proximal risk for suicidal ideation in adolescents / Jessica L. HAMILTON in Journal of Child Psychology and Psychiatry, 65-12 (December 2024)
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PermalinkPredicting 3-month risk for adolescent suicide attempts among pediatric emergency department patients / C. A. KING in Journal of Child Psychology and Psychiatry, 60-10 (October 2019)
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PermalinkPrevalence and correlates of mental disorders in Israeli adolescents: results from a national mental health survey / Ilana FARBSTEIN in Journal of Child Psychology and Psychiatry, 51-5 (May 2010)
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PermalinkSleep influences daily suicidal ideation through affective reactivity to interpersonal events among high-risk adolescents and young adults / Jessica L. HAMILTON in Journal of Child Psychology and Psychiatry, 64-1 (January 2023)
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PermalinkTesting the interpersonal theory of suicide in adolescents: A multi-wave longitudinal study / David PAGLIACCIO in Journal of Child Psychology and Psychiatry, 65-5 (May 2024)
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