Development of the Supported Employment, Comprehensive Cognitive Enhancement, and Social Skills program for adults on the autism spectrum: Results of initial study / Mary BAKER-ERICZEN in Autism, 22-1 (January 2018)  

Public ISBD [article]  inAutism > 22-1 (January 2018) . - p.6-19 Titre : Development of the Supported Employment, Comprehensive Cognitive Enhancement, and Social Skills program for adults on the autism spectrum: Results of initial study Type de document : texte imprimé Auteurs : Mary BAKER-ERICZEN, Auteur ; Meghan A. FITCH, Auteur ; Mikaela KINNEAR, Auteur ; Melissa JENKINS, Auteur ; Elizabeth W TWAMLEY, Auteur ; Linda SMITH, Auteur ; Gabriel MONTANO, Auteur ; Joshua FEDER, Auteur ; Pamela J. CROOKE, Auteur ; Michelle G. WINNER, Auteur ; Juan LEON, Auteur Article en page(s) : p.6-19 Langues : Anglais (eng) Mots-clés : adults with autism,executive functioning,intervention,social cognition,vocational training Index. décimale : PER Périodiques Résumé : The population of adults on the autism spectrum continues to increase, and vocational outcomes are particularly poor. Longitudinal studies of adults with autism spectrum and without intellectual disability have shown consistent and persistent deficits across cognitive, social, and vocational domains, indicating a need for effective treatments of functional disabilities as each impact employment. This initial pilot study is an open trial investigation of the feasibility, acceptability, and initial estimates of outcomes for the newly developed Supported Employment, Comprehensive Cognitive Enhancement, and Social Skills intervention, a manualized “soft skills” curriculum, to enhance both cognitive and social development in adults with autism spectrum. A total of eight adults with autism spectrum, without intellectual disability (78% males), participated in the study. Results support the original hypothesis that adults with autism spectrum can improve both cognitive (i.e. executive functioning) and social cognitive (i.e. social thinking and social communication) abilities. Further Supported Employment, Comprehensive Cognitive Enhancement, and Social Skills was found to be feasible, acceptable, and highly satisfactory for participants and parents. Employment rates more than doubled post-intervention, with an increase from 22% to 56% of participants employed. Conclusion is that Supported Employment, Comprehensive Cognitive Enhancement, and Social Skills has promise as an intervention that can be easily embedded into exiting supported employment vocational training programs to improve cognitive, social, and vocational outcomes. En ligne : https://doi.org/10.1177/1362361317724294 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=334 [article] Development of the Supported Employment, Comprehensive Cognitive Enhancement, and Social Skills program for adults on the autism spectrum: Results of initial study [texte imprimé] / Mary BAKER-ERICZEN, Auteur ; Meghan A. FITCH, Auteur ; Mikaela KINNEAR, Auteur ; Melissa JENKINS, Auteur ; Elizabeth W TWAMLEY, Auteur ; Linda SMITH, Auteur ; Gabriel MONTANO, Auteur ; Joshua FEDER, Auteur ; Pamela J. CROOKE, Auteur ; Michelle G. WINNER, Auteur ; Juan LEON, Auteur . - p.6-19. Langues : Anglais (eng) in Autism > 22-1 (January 2018) . - p.6-19 Mots-clés : adults with autism,executive functioning,intervention,social cognition,vocational training Index. décimale : PER Périodiques Résumé : The population of adults on the autism spectrum continues to increase, and vocational outcomes are particularly poor. Longitudinal studies of adults with autism spectrum and without intellectual disability have shown consistent and persistent deficits across cognitive, social, and vocational domains, indicating a need for effective treatments of functional disabilities as each impact employment. This initial pilot study is an open trial investigation of the feasibility, acceptability, and initial estimates of outcomes for the newly developed Supported Employment, Comprehensive Cognitive Enhancement, and Social Skills intervention, a manualized “soft skills” curriculum, to enhance both cognitive and social development in adults with autism spectrum. A total of eight adults with autism spectrum, without intellectual disability (78% males), participated in the study. Results support the original hypothesis that adults with autism spectrum can improve both cognitive (i.e. executive functioning) and social cognitive (i.e. social thinking and social communication) abilities. Further Supported Employment, Comprehensive Cognitive Enhancement, and Social Skills was found to be feasible, acceptable, and highly satisfactory for participants and parents. Employment rates more than doubled post-intervention, with an increase from 22% to 56% of participants employed. Conclusion is that Supported Employment, Comprehensive Cognitive Enhancement, and Social Skills has promise as an intervention that can be easily embedded into exiting supported employment vocational training programs to improve cognitive, social, and vocational outcomes. En ligne : https://doi.org/10.1177/1362361317724294 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=334

Externalizing Behaviors are Associated with Increased Parenting Stress in Caregivers of Young Children with Autism / Lindsay OLSON in Journal of Autism and Developmental Disorders, 52-3 (March 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-3 (March 2022) . - p.975-986 Titre : Externalizing Behaviors are Associated with Increased Parenting Stress in Caregivers of Young Children with Autism Type de document : texte imprimé Auteurs : Lindsay OLSON, Auteur ; Bosi CHEN, Auteur ; Cynthia IBARRA, Auteur ; Tiffany WANG, Auteur ; Lisa E. MASH, Auteur ; Annika LINKE, Auteur ; Mikaela KINNEAR, Auteur ; Inna FISHMAN, Auteur Article en page(s) : p.975-986 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis  Autistic Disorder  Caregivers  Child  Child, Preschool  Humans  Parenting  Parents  Asd  Early childhood  Externalizing behaviors  Parental stress Index. décimale : PER Périodiques Résumé : Parents of children diagnosed with autism spectrum disorder (ASD) report higher levels of stress than parents of typically developing children. Few studies have examined factors associated with parental stress in early childhood. Even fewer have investigated the simultaneous influence of sociodemographic, clinical, and developmental variables on parental stress. We examined factors associated with stress in parents of young children with ASD. Multiple regression models were used to test for associations between socioeconomic indices, developmental measures, and parental stress. Externalizing behaviors, communication, and socialization skills accounted for variance in parental stress, controlling for ASD diagnosis. Results highlight the importance of interventions aimed at reducing externalizing behaviors in young children as well as addressing stress in caregivers of children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-021-04995-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455 [article] Externalizing Behaviors are Associated with Increased Parenting Stress in Caregivers of Young Children with Autism [texte imprimé] / Lindsay OLSON, Auteur ; Bosi CHEN, Auteur ; Cynthia IBARRA, Auteur ; Tiffany WANG, Auteur ; Lisa E. MASH, Auteur ; Annika LINKE, Auteur ; Mikaela KINNEAR, Auteur ; Inna FISHMAN, Auteur . - p.975-986. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-3 (March 2022) . - p.975-986 Mots-clés : Autism Spectrum Disorder/diagnosis  Autistic Disorder  Caregivers  Child  Child, Preschool  Humans  Parenting  Parents  Asd  Early childhood  Externalizing behaviors  Parental stress Index. décimale : PER Périodiques Résumé : Parents of children diagnosed with autism spectrum disorder (ASD) report higher levels of stress than parents of typically developing children. Few studies have examined factors associated with parental stress in early childhood. Even fewer have investigated the simultaneous influence of sociodemographic, clinical, and developmental variables on parental stress. We examined factors associated with stress in parents of young children with ASD. Multiple regression models were used to test for associations between socioeconomic indices, developmental measures, and parental stress. Externalizing behaviors, communication, and socialization skills accounted for variance in parental stress, controlling for ASD diagnosis. Results highlight the importance of interventions aimed at reducing externalizing behaviors in young children as well as addressing stress in caregivers of children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-021-04995-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455

Functional connectivity within an anxiety network and associations with anxiety symptom severity in middle-aged adults with and without autism / Ryan TUNG in Autism Research, 14-10 (October 2021)  

Public ISBD [article]  inAutism Research > 14-10 (October 2021) . - p.2100-2112 Titre : Functional connectivity within an anxiety network and associations with anxiety symptom severity in middle-aged adults with and without autism Type de document : texte imprimé Auteurs : Ryan TUNG, Auteur ; Maya A. REITER, Auteur ; Annika LINKE, Auteur ; Jiwandeep S. KOHLI, Auteur ; Mikaela KINNEAR, Auteur ; Ralph-Axel MULLER, Auteur ; Ruth A. CARPER, Auteur Article en page(s) : p.2100-2112 Langues : Anglais (eng) Mots-clés : Adult  Anxiety/complications/diagnostic imaging  Autism Spectrum Disorder/complications/diagnostic imaging  Autistic Disorder/complications/diagnostic imaging  Brain/diagnostic imaging  Brain Mapping  Humans  Magnetic Resonance Imaging  Male  Middle Aged  Neural Pathways/diagnostic imaging  Asd  adults  anxiety  autism  functional connectivity  resting state fMRI Index. décimale : PER Périodiques Résumé : Anxiety is highly prevalent in autism spectrum disorders (ASDs). However, few functional magnetic resonance imaging (fMRI) studies of ASDs have focused on anxiety (and fewer still on anxiety in middle-aged adults). Thus, relationships between atypical connectivity and anxiety in this population are poorly understood. The current study contrasted functional connectivity within anxiety network regions across adults (40-64 years) with and without autism, and tested for group by functional connectivity interactions on anxiety. Twenty-two adults with ASDs (16 males) and 26 typical control (TC) adults (22 males) completed the Beck Anxiety Inventory and a resting-state fMRI scan. An anxiety network consisting of 12 regions of interest was defined, based on a meta-analysis in TC individuals and two studies on anxiety in ASDs. We tested for main effects of group and group by anxiety interactions on connectivity within this anxiety network, controlling for head motion using ANCOVA. Results are reported at an FDR adjusted threshold of q < 0.1 (corrected) and p < 0.05 (uncorrected). Adults with ASDs showed higher anxiety and underconnectivity within the anxiety network, mostly involving bilateral insula. Connectivity within the anxiety network in the ASD group showed distinct relationships with anxiety symptoms that did not relate to ASD symptom severity. Functional connectivity involving the bilateral posterior insula was positively correlated with anxiety in the ASD (but not the TC) group. Increased anxiety in middle-aged adults with ASD is associated with atypical functional connectivity, predominantly involving bilateral insula. Results were not related to ASD symptom severity suggesting independence of anxiety-related effects. LAY SUMMARY: Anxiety is very common in adults with autism but the brain basis of this difference is not well understood. We compared functional connectivity between anxiety-related brain regions in middle-aged adults with and without autism. Adults with autism were more anxious and showed weaker functional connections between these regions. Some relationships between functional connectivity and higher anxiety were specific to the autism group. Results suggest that anxiety functions differently in autism. En ligne : http://dx.doi.org/10.1002/aur.2579 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] Functional connectivity within an anxiety network and associations with anxiety symptom severity in middle-aged adults with and without autism [texte imprimé] / Ryan TUNG, Auteur ; Maya A. REITER, Auteur ; Annika LINKE, Auteur ; Jiwandeep S. KOHLI, Auteur ; Mikaela KINNEAR, Auteur ; Ralph-Axel MULLER, Auteur ; Ruth A. CARPER, Auteur . - p.2100-2112. Langues : Anglais (eng) in Autism Research > 14-10 (October 2021) . - p.2100-2112 Mots-clés : Adult  Anxiety/complications/diagnostic imaging  Autism Spectrum Disorder/complications/diagnostic imaging  Autistic Disorder/complications/diagnostic imaging  Brain/diagnostic imaging  Brain Mapping  Humans  Magnetic Resonance Imaging  Male  Middle Aged  Neural Pathways/diagnostic imaging  Asd  adults  anxiety  autism  functional connectivity  resting state fMRI Index. décimale : PER Périodiques Résumé : Anxiety is highly prevalent in autism spectrum disorders (ASDs). However, few functional magnetic resonance imaging (fMRI) studies of ASDs have focused on anxiety (and fewer still on anxiety in middle-aged adults). Thus, relationships between atypical connectivity and anxiety in this population are poorly understood. The current study contrasted functional connectivity within anxiety network regions across adults (40-64 years) with and without autism, and tested for group by functional connectivity interactions on anxiety. Twenty-two adults with ASDs (16 males) and 26 typical control (TC) adults (22 males) completed the Beck Anxiety Inventory and a resting-state fMRI scan. An anxiety network consisting of 12 regions of interest was defined, based on a meta-analysis in TC individuals and two studies on anxiety in ASDs. We tested for main effects of group and group by anxiety interactions on connectivity within this anxiety network, controlling for head motion using ANCOVA. Results are reported at an FDR adjusted threshold of q < 0.1 (corrected) and p < 0.05 (uncorrected). Adults with ASDs showed higher anxiety and underconnectivity within the anxiety network, mostly involving bilateral insula. Connectivity within the anxiety network in the ASD group showed distinct relationships with anxiety symptoms that did not relate to ASD symptom severity. Functional connectivity involving the bilateral posterior insula was positively correlated with anxiety in the ASD (but not the TC) group. Increased anxiety in middle-aged adults with ASD is associated with atypical functional connectivity, predominantly involving bilateral insula. Results were not related to ASD symptom severity suggesting independence of anxiety-related effects. LAY SUMMARY: Anxiety is very common in adults with autism but the brain basis of this difference is not well understood. We compared functional connectivity between anxiety-related brain regions in middle-aged adults with and without autism. Adults with autism were more anxious and showed weaker functional connections between these regions. Some relationships between functional connectivity and higher anxiety were specific to the autism group. Results suggest that anxiety functions differently in autism. En ligne : http://dx.doi.org/10.1002/aur.2579 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

Greater functional connectivity between sensory networks is related to symptom severity in toddlers with autism spectrum disorder / Bosi CHEN in Journal of Child Psychology and Psychiatry, 62-2 (February 2021)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 62-2 (February 2021) . - p.160-170 Titre : Greater functional connectivity between sensory networks is related to symptom severity in toddlers with autism spectrum disorder Type de document : texte imprimé Auteurs : Bosi CHEN, Auteur ; Annika LINKE, Auteur ; Lindsay OLSON, Auteur ; Cynthia IBARRA, Auteur ; Sarah REYNOLDS, Auteur ; Ralph-Axel MULLER, Auteur ; Mikaela KINNEAR, Auteur ; Inna FISHMAN, Auteur Année de publication : 2021 Article en page(s) : p.160-170 Langues : Anglais (eng) Mots-clés : Brain networks  autism spectrum disorders  early childhood  functional connectivity  neuroimaging Index. décimale : PER Périodiques Résumé : BACKGROUND: Symptoms of autism spectrum disorder (ASD) emerge in the first years of life. Yet, little is known about the organization and development of functional brain networks in ASD proximally to the symptom onset. Further, the relationship between brain network connectivity and emerging ASD symptoms and overall functioning in early childhood is not well understood. METHODS: Resting-state fMRI data were acquired during natural sleep from 24 young children with ASD and 23 typically developing (TD) children, aged 17-45 months. Intrinsic functional connectivity (iFC) within and between resting-state functional networks was derived with independent component analysis (ICA). RESULTS: Increased iFC between visual and sensorimotor networks was found in young children with ASD compared to TD participants. Within the ASD group, the degree of overconnectivity between visual and sensorimotor networks was associated with greater autism symptoms. Age-related weakening of the visual-auditory between-network connectivity was observed in the ASD but not the TD group. CONCLUSIONS: Taken together, these results provide evidence for disrupted functional network maturation and differentiation, particularly involving visual and sensorimotor networks, during the first years of life in ASD. The observed pattern of greater visual-sensorimotor between-network connectivity associated with poorer clinical outcomes suggests that disruptions in multisensory brain circuitry may play a critical role for early development of behavioral skills and autism symptomatology in young children with ASD. En ligne : http://dx.doi.org/10.1111/jcpp.13268 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=440 [article] Greater functional connectivity between sensory networks is related to symptom severity in toddlers with autism spectrum disorder [texte imprimé] / Bosi CHEN, Auteur ; Annika LINKE, Auteur ; Lindsay OLSON, Auteur ; Cynthia IBARRA, Auteur ; Sarah REYNOLDS, Auteur ; Ralph-Axel MULLER, Auteur ; Mikaela KINNEAR, Auteur ; Inna FISHMAN, Auteur . - 2021 . - p.160-170. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 62-2 (February 2021) . - p.160-170 Mots-clés : Brain networks  autism spectrum disorders  early childhood  functional connectivity  neuroimaging Index. décimale : PER Périodiques Résumé : BACKGROUND: Symptoms of autism spectrum disorder (ASD) emerge in the first years of life. Yet, little is known about the organization and development of functional brain networks in ASD proximally to the symptom onset. Further, the relationship between brain network connectivity and emerging ASD symptoms and overall functioning in early childhood is not well understood. METHODS: Resting-state fMRI data were acquired during natural sleep from 24 young children with ASD and 23 typically developing (TD) children, aged 17-45 months. Intrinsic functional connectivity (iFC) within and between resting-state functional networks was derived with independent component analysis (ICA). RESULTS: Increased iFC between visual and sensorimotor networks was found in young children with ASD compared to TD participants. Within the ASD group, the degree of overconnectivity between visual and sensorimotor networks was associated with greater autism symptoms. Age-related weakening of the visual-auditory between-network connectivity was observed in the ASD but not the TD group. CONCLUSIONS: Taken together, these results provide evidence for disrupted functional network maturation and differentiation, particularly involving visual and sensorimotor networks, during the first years of life in ASD. The observed pattern of greater visual-sensorimotor between-network connectivity associated with poorer clinical outcomes suggests that disruptions in multisensory brain circuitry may play a critical role for early development of behavioral skills and autism symptomatology in young children with ASD. En ligne : http://dx.doi.org/10.1111/jcpp.13268 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=440

Neural correlates of verbal and nonverbal semantic integration in children with autism spectrum disorders / Joseph P. MCCLEERY in Journal of Child Psychology and Psychiatry, 51-3 (March 2010)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 51-3 (March 2010) . - p.277-286 Titre : Neural correlates of verbal and nonverbal semantic integration in children with autism spectrum disorders Type de document : texte imprimé Auteurs : Joseph P. MCCLEERY, Auteur ; Laura SCHREIBMAN, Auteur ; Rita CEPONIENE, Auteur ; Karen M. BURNER, Auteur ; Jeanne TOWNSEND, Auteur ; Mikaela KINNEAR, Auteur Année de publication : 2010 Article en page(s) : p.277-286 Langues : Anglais (eng) Mots-clés : Event-related-potentials N400 words environmental-sounds Index. décimale : PER Périodiques Résumé : Background: Autism is a pervasive developmental disorder characterized by deficits in social-emotional, social-communicative, and language skills. Behavioral and neuroimaging studies have found that children with autism spectrum disorders (ASD) evidence abnormalities in semantic processing, with particular difficulties in verbal comprehension. However, it is not known whether these semantic deficits are confined to the verbal domain or represent a more general problem with semantic processing. The focus of the current study was to investigate verbal and meaningful nonverbal semantic processing in high-functioning children with autism (mean age = 5.8 years) using event-related potentials (ERPs). Method: ERPs were recorded while children attended to semantically matching and mismatching picture–word and picture–environmental sound pairs. Results: ERPs of typically developing children exhibited evidence of semantic incongruency detection in both the word and environmental sound conditions, as indexed by elicitation of an N400 effect. In contrast, children with ASD showed an N400 effect in the environmental sound condition but not in the word condition. Conclusions: These results provide evidence for a deficiency in the automatic activation of semantic representations in children with ASD, and suggest that this deficit is somewhat more selective to, or more severe in, the verbal than the nonverbal domain. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2009.02157.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=988 [article] Neural correlates of verbal and nonverbal semantic integration in children with autism spectrum disorders [texte imprimé] / Joseph P. MCCLEERY, Auteur ; Laura SCHREIBMAN, Auteur ; Rita CEPONIENE, Auteur ; Karen M. BURNER, Auteur ; Jeanne TOWNSEND, Auteur ; Mikaela KINNEAR, Auteur . - 2010 . - p.277-286. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 51-3 (March 2010) . - p.277-286 Mots-clés : Event-related-potentials N400 words environmental-sounds Index. décimale : PER Périodiques Résumé : Background: Autism is a pervasive developmental disorder characterized by deficits in social-emotional, social-communicative, and language skills. Behavioral and neuroimaging studies have found that children with autism spectrum disorders (ASD) evidence abnormalities in semantic processing, with particular difficulties in verbal comprehension. However, it is not known whether these semantic deficits are confined to the verbal domain or represent a more general problem with semantic processing. The focus of the current study was to investigate verbal and meaningful nonverbal semantic processing in high-functioning children with autism (mean age = 5.8 years) using event-related potentials (ERPs). Method: ERPs were recorded while children attended to semantically matching and mismatching picture–word and picture–environmental sound pairs. Results: ERPs of typically developing children exhibited evidence of semantic incongruency detection in both the word and environmental sound conditions, as indexed by elicitation of an N400 effect. In contrast, children with ASD showed an N400 effect in the environmental sound condition but not in the word condition. Conclusions: These results provide evidence for a deficiency in the automatic activation of semantic representations in children with ASD, and suggest that this deficit is somewhat more selective to, or more severe in, the verbal than the nonverbal domain. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2009.02157.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=988

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