An Evaluation of the Applicability of the Tripartite Constructs to Social Anxiety in Adolescents / Emily R. ANDERSON in Journal of Clinical Child & Adolescent Psychology, 39-2 (March-April 2010)  

Public ISBD [article]  inJournal of Clinical Child & Adolescent Psychology > 39-2 (March-April 2010) . - p.195-207 Titre : An Evaluation of the Applicability of the Tripartite Constructs to Social Anxiety in Adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Emily R. ANDERSON, Auteur ; Glen J. VEED, Auteur ; Heidi M. INDERBITZEN-NOLAN, Auteur ; David J. HANSEN, Auteur Année de publication : 2010 Article en page(s) : p.195-207 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The current study examined the tripartite model of anxiety and depression in relation to social phobia in a nonclinical sample of adolescents (ages 13-17). Adolescent/parent dyads participated in a semistructured interview and completed self-report measures of the tripartite constructs and social anxiety. Adolescents gave an impromptu speech, and heart rate was monitored. Low positive affect, high negative affect, and high physiological hyperarousal were characteristic of adolescents diagnosed with social phobia; adolescents with elevated social anxiety symptoms who did not meet criteria for social phobia did not evidence low positive affect. Heart rate reactivity during the speech was not significantly correlated with social anxiety symptomatology or with self-reported physiological hyperarousal. En ligne : http://dx.doi.org/10.1080/15374410903532643 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=990 [article] An Evaluation of the Applicability of the Tripartite Constructs to Social Anxiety in Adolescents [Texte imprimé et/ou numérique] / Emily R. ANDERSON, Auteur ; Glen J. VEED, Auteur ; Heidi M. INDERBITZEN-NOLAN, Auteur ; David J. HANSEN, Auteur . - 2010 . - p.195-207. Langues : Anglais (eng) in Journal of Clinical Child & Adolescent Psychology > 39-2 (March-April 2010) . - p.195-207 Index. décimale : PER Périodiques Résumé : The current study examined the tripartite model of anxiety and depression in relation to social phobia in a nonclinical sample of adolescents (ages 13-17). Adolescent/parent dyads participated in a semistructured interview and completed self-report measures of the tripartite constructs and social anxiety. Adolescents gave an impromptu speech, and heart rate was monitored. Low positive affect, high negative affect, and high physiological hyperarousal were characteristic of adolescents diagnosed with social phobia; adolescents with elevated social anxiety symptoms who did not meet criteria for social phobia did not evidence low positive affect. Heart rate reactivity during the speech was not significantly correlated with social anxiety symptomatology or with self-reported physiological hyperarousal. En ligne : http://dx.doi.org/10.1080/15374410903532643 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=990

Autism spectrum disorders in Hispanics and non-Hispanics / Virginia CHAIDEZ in Autism, 16-4 (July 2012)  

Public ISBD [article]  inAutism > 16-4 (July 2012) . - p.381-397 Titre : Autism spectrum disorders in Hispanics and non-Hispanics Type de document : Texte imprimé et/ou numérique Auteurs : Virginia CHAIDEZ, Auteur ; David J. HANSEN, Auteur ; Irva HERTZ-PICCIOTTO, Auteur Année de publication : 2012 Article en page(s) : p.381-397 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Objectives To compare differences in autism between Hispanic and non-Hispanics. We also examined the relationship between multiple language exposure and language function and scores of children.Methods The Childhood Autism Risks from Genetics and the Environment (CHARGE) study is an ongoing population-based case-control study with children sampled (n=1061) from three strata: those with autism (AU) or autism spectrum disorder (ASD); developmental delay (DD); or the general population (GP).Results Non-Hispanic cases demonstrated higher cognitive composite scores for the Mullen Scales of Early Learning (MSEL). There were significant associations between multiple language exposure and MSEL subscales for receptive language and expressive language, in both cases (AU/ASD) and TD controls, but not DD controls. Results of multivariate regression analyses suggest several predictors to be associated with lower Mullen expressive language scores including: diagnosis of ASD/AU, speaking to the child in a second language 25-50% of the time and Hispanic ethnicity; while maternal college education was associated with higher scores.Conclusion Overall, the CHARGE Hispanic group displayed more similarities than differences compared to non-Hispanics in terms of autistic phenotypes and maladaptive & adaptive scores for cases. The relationship between multiple language use and cognitive scores warrants a closer look. En ligne : http://dx.doi.org/10.1177/1362361311434787 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178 [article] Autism spectrum disorders in Hispanics and non-Hispanics [Texte imprimé et/ou numérique] / Virginia CHAIDEZ, Auteur ; David J. HANSEN, Auteur ; Irva HERTZ-PICCIOTTO, Auteur . - 2012 . - p.381-397. Langues : Anglais (eng) in Autism > 16-4 (July 2012) . - p.381-397 Index. décimale : PER Périodiques Résumé : Objectives To compare differences in autism between Hispanic and non-Hispanics. We also examined the relationship between multiple language exposure and language function and scores of children.Methods The Childhood Autism Risks from Genetics and the Environment (CHARGE) study is an ongoing population-based case-control study with children sampled (n=1061) from three strata: those with autism (AU) or autism spectrum disorder (ASD); developmental delay (DD); or the general population (GP).Results Non-Hispanic cases demonstrated higher cognitive composite scores for the Mullen Scales of Early Learning (MSEL). There were significant associations between multiple language exposure and MSEL subscales for receptive language and expressive language, in both cases (AU/ASD) and TD controls, but not DD controls. Results of multivariate regression analyses suggest several predictors to be associated with lower Mullen expressive language scores including: diagnosis of ASD/AU, speaking to the child in a second language 25-50% of the time and Hispanic ethnicity; while maternal college education was associated with higher scores.Conclusion Overall, the CHARGE Hispanic group displayed more similarities than differences compared to non-Hispanics in terms of autistic phenotypes and maladaptive & adaptive scores for cases. The relationship between multiple language use and cognitive scores warrants a closer look. En ligne : http://dx.doi.org/10.1177/1362361311434787 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178

Behavioral Correlates of Maternal Antibody Status Among Children with Autism / Daniel BRAUNSCHWEIG in Journal of Autism and Developmental Disorders, 42-7 (July 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1435-1445 Titre : Behavioral Correlates of Maternal Antibody Status Among Children with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Daniel BRAUNSCHWEIG, Auteur ; Paul DUNCANSON, Auteur ; Robert BOYCE, Auteur ; David J. HANSEN, Auteur ; Paul ASHWOOD, Auteur ; Isaac N. PESSAH, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Judy VAN DE WATER, Auteur Année de publication : 2012 Article en page(s) : p.1435-1445 Langues : Anglais (eng) Mots-clés : Autism  Maternal antibodies  Autoantibodies  Fetal brain  Immunologie Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASDs) affect approximately 1 in 110 children in the United States. This report profiles fetal-brain reactive autoantibodies of a large cohort of mothers of children with autism and controls, yielding significant associations between the presence of IgG reactivity to fetal brain proteins at 37 and 73 kDa and a childhood diagnosis of full autism (p = 0.0005), which also correlated with lower expressive language scores (p = 0.005). Additionally, we report on reactivity to proteins at 39 and 73 kDa, which correlated with the broader diagnosis of ASD (p = 0.0007) and increased irritability on the Aberrant Behavioral Checklist (p = 0.05). This study provides evidence of multiple patterns of reactivity to fetal brain proteins by maternal antibodies associated with ASD and specific childhood behavioral outcomes. En ligne : http://dx.doi.org/10.1007/s10803-011-1378-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166 [article] Behavioral Correlates of Maternal Antibody Status Among Children with Autism [Texte imprimé et/ou numérique] / Daniel BRAUNSCHWEIG, Auteur ; Paul DUNCANSON, Auteur ; Robert BOYCE, Auteur ; David J. HANSEN, Auteur ; Paul ASHWOOD, Auteur ; Isaac N. PESSAH, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Judy VAN DE WATER, Auteur . - 2012 . - p.1435-1445. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1435-1445 Mots-clés : Autism  Maternal antibodies  Autoantibodies  Fetal brain  Immunologie Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASDs) affect approximately 1 in 110 children in the United States. This report profiles fetal-brain reactive autoantibodies of a large cohort of mothers of children with autism and controls, yielding significant associations between the presence of IgG reactivity to fetal brain proteins at 37 and 73 kDa and a childhood diagnosis of full autism (p = 0.0005), which also correlated with lower expressive language scores (p = 0.005). Additionally, we report on reactivity to proteins at 39 and 73 kDa, which correlated with the broader diagnosis of ASD (p = 0.0007) and increased irritability on the Aberrant Behavioral Checklist (p = 0.05). This study provides evidence of multiple patterns of reactivity to fetal brain proteins by maternal antibodies associated with ASD and specific childhood behavioral outcomes. En ligne : http://dx.doi.org/10.1007/s10803-011-1378-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166

Brain-derived neurotrophic factor and autism: maternal and infant peripheral blood levels in the Early Markers for Autism (EMA) study / Lisa A. CROEN in Autism Research, 1-2 (April 2008)  

Public ISBD [article]  inAutism Research > 1-2 (April 2008) . - p.130-137 Titre : Brain-derived neurotrophic factor and autism: maternal and infant peripheral blood levels in the Early Markers for Autism (EMA) study Type de document : Texte imprimé et/ou numérique Auteurs : Lisa A. CROEN, Auteur ; David J. HANSEN, Auteur ; Martin KHARRAZI, Auteur ; Bruce FIREMAN, Auteur ; Cathleen K. YOSHIDA, Auteur ; Robert YOLKEN, Auteur ; Daniel BRAUNSCHWEIG, Auteur ; Paula GOINES, Auteur ; Judy VAN DE WATER, Auteur ; Judith K. GRETHER, Auteur Année de publication : 2008 Article en page(s) : p.130-137 Langues : Anglais (eng) Mots-clés : biologic-markers neurotrophin autism BDNF prenatal Index. décimale : PER Périodiques Résumé : To investigate levels of brain-derived neurotrophic factor (BDNF) in mid-pregnancy and neonatal blood specimens as early biologic markers for autism, we conducted a population-based case-control study nested within the cohort of infants born from July 2000 to September 2001 to women who participated in the prenatal screening program in Orange County, CA. Cases (n=84) were all children receiving services for autism at the Regional Center of Orange County. Two comparison groups from the same study population were included: children with mental retardation or developmental delay (n=49) receiving services at the same regional center, and children not receiving services for developmental disabilities, randomly sampled from the California birth certificate files (n=159), and frequency matched to autism cases on sex, birth year, and birth month. BDNF concentrations were measured in archived mid-pregnancy and neonatal blood specimens drawn during routine prenatal and newborn screening using a highly sensitive bead-based assay (Luminex, Biosource Human BDNF Antibody Bead Kit, Invitrogen-Biosource, Carlsbad, CA). The concentration of BDNF in maternal mid-pregnancy and neonatal specimens was similar across all three study groups. These data do not support previous findings of an association between BDNF and autism and suggest that the concentration of BDNF during critical periods of early neurodevelopment is not likely to be a useful biomarker for autism susceptibility. En ligne : http://dx.doi.org/10.1002/aur.14 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=930 [article] Brain-derived neurotrophic factor and autism: maternal and infant peripheral blood levels in the Early Markers for Autism (EMA) study [Texte imprimé et/ou numérique] / Lisa A. CROEN, Auteur ; David J. HANSEN, Auteur ; Martin KHARRAZI, Auteur ; Bruce FIREMAN, Auteur ; Cathleen K. YOSHIDA, Auteur ; Robert YOLKEN, Auteur ; Daniel BRAUNSCHWEIG, Auteur ; Paula GOINES, Auteur ; Judy VAN DE WATER, Auteur ; Judith K. GRETHER, Auteur . - 2008 . - p.130-137. Langues : Anglais (eng) in Autism Research > 1-2 (April 2008) . - p.130-137 Mots-clés : biologic-markers neurotrophin autism BDNF prenatal Index. décimale : PER Périodiques Résumé : To investigate levels of brain-derived neurotrophic factor (BDNF) in mid-pregnancy and neonatal blood specimens as early biologic markers for autism, we conducted a population-based case-control study nested within the cohort of infants born from July 2000 to September 2001 to women who participated in the prenatal screening program in Orange County, CA. Cases (n=84) were all children receiving services for autism at the Regional Center of Orange County. Two comparison groups from the same study population were included: children with mental retardation or developmental delay (n=49) receiving services at the same regional center, and children not receiving services for developmental disabilities, randomly sampled from the California birth certificate files (n=159), and frequency matched to autism cases on sex, birth year, and birth month. BDNF concentrations were measured in archived mid-pregnancy and neonatal blood specimens drawn during routine prenatal and newborn screening using a highly sensitive bead-based assay (Luminex, Biosource Human BDNF Antibody Bead Kit, Invitrogen-Biosource, Carlsbad, CA). The concentration of BDNF in maternal mid-pregnancy and neonatal specimens was similar across all three study groups. These data do not support previous findings of an association between BDNF and autism and suggest that the concentration of BDNF during critical periods of early neurodevelopment is not likely to be a useful biomarker for autism susceptibility. En ligne : http://dx.doi.org/10.1002/aur.14 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=930

Brief Report: Plasma Leptin Levels are Elevated in Autism: Association with Early Onset Phenotype? / Paul ASHWOOD in Journal of Autism and Developmental Disorders, 38-1 (January 2008)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 38-1 (January 2008) . - p.169-175 Titre : Brief Report: Plasma Leptin Levels are Elevated in Autism: Association with Early Onset Phenotype? Type de document : Texte imprimé et/ou numérique Auteurs : Paul ASHWOOD, Auteur ; Christina KWONG, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Paula KRAKOWIAK, Auteur ; Wynn WALKER, Auteur ; Isaac N. PESSAH, Auteur ; Judy VAN DE WATER, Auteur ; David J. HANSEN, Auteur ; Lisa A. CROEN, Auteur Année de publication : 2008 Article en page(s) : p.169-175 Langues : Anglais (eng) Mots-clés : Inflammation Leptin Autism Regression Index. décimale : PER Périodiques Résumé : There is evidence of both immune dysregulation and autoimmune phenomena in children with autism spectrum disorders (ASD). We examined the hormone/cytokine leptin in 70 children diagnosed with autism (including 37 with regression) compared with 99 age-matched controls including 50 typically developing (TD) controls, 26 siblings without autism, and 23 children with developmental disabilities (DD). Children with autism had significantly higher plasma leptin levels compared with TD controls (p < .006). When further sub-classified into regression or early onset autism, children with early onset autism had significantly higher plasma leptin levels compared with children with regressive autism (p < .042), TD controls (p < .0015), and DD controls (p < .004). We demonstrated an increase in leptin levels in autism, a finding driven by the early onset group. En ligne : http://dx.doi.org/10.1007/s10803-006-0353-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=316 [article] Brief Report: Plasma Leptin Levels are Elevated in Autism: Association with Early Onset Phenotype? [Texte imprimé et/ou numérique] / Paul ASHWOOD, Auteur ; Christina KWONG, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Paula KRAKOWIAK, Auteur ; Wynn WALKER, Auteur ; Isaac N. PESSAH, Auteur ; Judy VAN DE WATER, Auteur ; David J. HANSEN, Auteur ; Lisa A. CROEN, Auteur . - 2008 . - p.169-175. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 38-1 (January 2008) . - p.169-175 Mots-clés : Inflammation Leptin Autism Regression Index. décimale : PER Périodiques Résumé : There is evidence of both immune dysregulation and autoimmune phenomena in children with autism spectrum disorders (ASD). We examined the hormone/cytokine leptin in 70 children diagnosed with autism (including 37 with regression) compared with 99 age-matched controls including 50 typically developing (TD) controls, 26 siblings without autism, and 23 children with developmental disabilities (DD). Children with autism had significantly higher plasma leptin levels compared with TD controls (p < .006). When further sub-classified into regression or early onset autism, children with early onset autism had significantly higher plasma leptin levels compared with children with regressive autism (p < .042), TD controls (p < .0015), and DD controls (p < .004). We demonstrated an increase in leptin levels in autism, a finding driven by the early onset group. En ligne : http://dx.doi.org/10.1007/s10803-006-0353-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=316

A Double-Blind, Placebo-Controlled Trial of Oral Human Immunoglobulin for Gastrointestinal Dysfunction in Children with Autistic Disorder / Benjamin L. HANDEN in Journal of Autism and Developmental Disorders, 39-5 (May 2009)  

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Identification of Expanded Alleles of the FMR1 Gene in the CHildhood Autism Risks from Genes and Environment (CHARGE) Study / Flora TASSONE in Journal of Autism and Developmental Disorders, 43-3 (March 2013)  

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Identifying, assessing, and treating autism at school / Stephen E. BROCK

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Increased mid-gestational IFN-gamma, IL-4, and IL-5 in women giving birth to a child with autism: a case-control study / Paula GOINES in Molecular Autism, (August 2011)  

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MAOA, DBH, and SLC6A4 variants in CHARGE: a case–control study of autism spectrum disorders / Flora TASSONE in Autism Research, 4-4 (August 2011)  

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MECP2 promoter methylation and X chromosome inactivation in autism / Raman P. NAGARAJAN in Autism Research, 1-3 (June 2008)  

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Minor physical anomalies in children with autism spectrum disorders / Kathleen ANGKUSTSIRI in Autism, 15-6 (November 2011)  

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Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms / Luke HEUER in Autism Research, 1-5 (October 2008)  

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The onset of autism: patterns of symptom emergence in the first years of life / Sally OZONOFF in Autism Research, 1-6 (December 2008)  

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