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Auteur Harriet L. MACMILLAN
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Documents disponibles écrits par cet auteur (3)
Faire une suggestion Affiner la rechercheAdolescent females exposed to child maltreatment exhibit atypical EEG coherence and psychiatric impairment: Linking early adversity, the brain, and psychopathology / Vladimir MISKOVIC in Development and Psychopathology, 22-2 (May 2010)
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[article]
Titre : Adolescent females exposed to child maltreatment exhibit atypical EEG coherence and psychiatric impairment: Linking early adversity, the brain, and psychopathology Type de document : texte imprimé Auteurs : Vladimir MISKOVIC, Auteur ; Katholiki GEORGIADES, Auteur ; Michael H. BOYLE, Auteur ; Louis A. SCHMIDT, Auteur ; Harriet L. MACMILLAN, Auteur Année de publication : 2010 Article en page(s) : p.419-432 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Although the relation between child maltreatment and psychiatric impairment is well documented and preliminary evidence has linked child maltreatment with aberrant cortical connectivity of the left hemisphere, no investigations have attempted to examine these relations in the same study. Here, we examined the links among early adversity, brain connectivity, and functional outcomes. We collected resting regional EEG intra- and interhemispheric α-band (7.5–12.5 Hz) coherence and measures of general psychiatric impairment from a cohort of 38 adolescent females exposed to child maltreatment (M age = 14.47) and 24 adolescent females not exposed to child maltreatment (M age = 14.00). Maltreated youths exhibited more left hemisphere EEG coherence than the control youths, suggesting a suboptimal organization of cortical networks. Maltreated participants also showed reduced frontal (anterior) interhemispheric coherence. These differences in brain circuitry remained statistically significant even after controlling for group differences in pubertal status and socioeconomic status. Measures of functional brain connectivity were associated with several subtypes of abuse and neglect. It was important that atypical left hemisphere EEG coherence mediated the effects of child maltreatment on levels of psychiatric impairment. The findings are discussed in the context of models linking early adversity to brain function and psychopathology. En ligne : http://dx.doi.org/10.1017/s0954579410000155 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=102
in Development and Psychopathology > 22-2 (May 2010) . - p.419-432[article] Adolescent females exposed to child maltreatment exhibit atypical EEG coherence and psychiatric impairment: Linking early adversity, the brain, and psychopathology [texte imprimé] / Vladimir MISKOVIC, Auteur ; Katholiki GEORGIADES, Auteur ; Michael H. BOYLE, Auteur ; Louis A. SCHMIDT, Auteur ; Harriet L. MACMILLAN, Auteur . - 2010 . - p.419-432.
Langues : Anglais (eng)
in Development and Psychopathology > 22-2 (May 2010) . - p.419-432
Index. décimale : PER Périodiques Résumé : Although the relation between child maltreatment and psychiatric impairment is well documented and preliminary evidence has linked child maltreatment with aberrant cortical connectivity of the left hemisphere, no investigations have attempted to examine these relations in the same study. Here, we examined the links among early adversity, brain connectivity, and functional outcomes. We collected resting regional EEG intra- and interhemispheric α-band (7.5–12.5 Hz) coherence and measures of general psychiatric impairment from a cohort of 38 adolescent females exposed to child maltreatment (M age = 14.47) and 24 adolescent females not exposed to child maltreatment (M age = 14.00). Maltreated youths exhibited more left hemisphere EEG coherence than the control youths, suggesting a suboptimal organization of cortical networks. Maltreated participants also showed reduced frontal (anterior) interhemispheric coherence. These differences in brain circuitry remained statistically significant even after controlling for group differences in pubertal status and socioeconomic status. Measures of functional brain connectivity were associated with several subtypes of abuse and neglect. It was important that atypical left hemisphere EEG coherence mediated the effects of child maltreatment on levels of psychiatric impairment. The findings are discussed in the context of models linking early adversity to brain function and psychopathology. En ligne : http://dx.doi.org/10.1017/s0954579410000155 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=102 Effectiveness of nurse-home visiting in improving child and maternal outcomes prenatally to age two years: a randomised controlled trial (British Columbia Healthy Connections Project) / Nicole L.A. CATHERINE in Journal of Child Psychology and Psychiatry, 65-5 (May 2024)
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[article]
Titre : Effectiveness of nurse-home visiting in improving child and maternal outcomes prenatally to age two years: a randomised controlled trial (British Columbia Healthy Connections Project) Type de document : texte imprimé Auteurs : Nicole L.A. CATHERINE, Auteur ; Harriet L. MACMILLAN, Auteur ; Ange CULLEN, Auteur ; Yufei ZHENG, Auteur ; Hui XIE, Auteur ; Michael H. BOYLE, Auteur ; Debbie SHEEHAN, Auteur ; Rosemary LEVER, Auteur ; Susan M. JACK, Auteur ; Andrea GONZALEZ, Auteur ; Amiram GAFNI, Auteur ; Lil TONMYR, Auteur ; Ronald G. BARR, Auteur ; Lenora MARCELLUS, Auteur ; Colleen VARCOE, Auteur ; Charlotte WADDELL, Auteur Article en page(s) : p.644-655 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background We investigated the effectiveness of Nurse-Family Partnership (NFP), a prenatal-to-age-two-years home-visiting programme, in British Columbia (BC), Canada. Methods For this randomised controlled trial, we recruited participants from 26 public health settings who were: <25 years, nulliparous, <28 weeks gestation and experiencing socioeconomic disadvantage. We randomly allocated participants (one-to-one; computer-generated) to intervention (NFP plus existing services) or comparison (existing services) groups. Prespecified outcomes were prenatal substance exposure (reported previously); child injuries (primary), language, cognition and mental health (problem behaviour) by age two years; and subsequent pregnancies by 24 months postpartum. Research interviewers were masked. We used intention-to-treat analyses. (ClinicalTrials.gov, NCT01672060.) Results From 2013 to 2016 we enrolled 739 participants (368 NFP, 371 comparison) who had 737 children. Counts for child injury healthcare encounters [rate per 1,000 person-years or RPY] were similar for NFP (223 [RPY 316.17]) and comparison (223 [RPY 305.43]; rate difference 10.74, 95% CI -46.96, 68.44; rate ratio 1.03, 95% CI 0.78, 1.38). Maternal-reported language scores (mean, M [SD]) were statistically significantly higher for NFP (313.46 [195.96]) than comparison (282.77 [188.15]; mean difference [MD] 31.33, 95% CI 0.96, 61.71). Maternal-reported problem-behaviour scores (M [SD]) were statistically significantly lower for NFP (52.18 [9.19]) than comparison (54.42 [9.02]; MD -2.19, 95% CI 3.62, 0.75). Subsequent pregnancy counts were similar (NFP 115 [RPY 230.69] and comparison 117 [RPY 227.29]; rate difference 3.40, 95% CI -55.54, 62.34; hazard ratio 1.01, 95% CI 0.79, 1.29). We observed no unanticipated adverse events. Conclusions NFP did not reduce child injuries or subsequent maternal pregnancies but did improve maternal-reported child language and mental health (problem behaviour) at age two years. Follow-up of long-term outcomes is warranted given that further benefits may emerge across childhood and adolescence. En ligne : https://doi.org/10.1111/jcpp.13846 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=526
in Journal of Child Psychology and Psychiatry > 65-5 (May 2024) . - p.644-655[article] Effectiveness of nurse-home visiting in improving child and maternal outcomes prenatally to age two years: a randomised controlled trial (British Columbia Healthy Connections Project) [texte imprimé] / Nicole L.A. CATHERINE, Auteur ; Harriet L. MACMILLAN, Auteur ; Ange CULLEN, Auteur ; Yufei ZHENG, Auteur ; Hui XIE, Auteur ; Michael H. BOYLE, Auteur ; Debbie SHEEHAN, Auteur ; Rosemary LEVER, Auteur ; Susan M. JACK, Auteur ; Andrea GONZALEZ, Auteur ; Amiram GAFNI, Auteur ; Lil TONMYR, Auteur ; Ronald G. BARR, Auteur ; Lenora MARCELLUS, Auteur ; Colleen VARCOE, Auteur ; Charlotte WADDELL, Auteur . - p.644-655.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 65-5 (May 2024) . - p.644-655
Index. décimale : PER Périodiques Résumé : Background We investigated the effectiveness of Nurse-Family Partnership (NFP), a prenatal-to-age-two-years home-visiting programme, in British Columbia (BC), Canada. Methods For this randomised controlled trial, we recruited participants from 26 public health settings who were: <25 years, nulliparous, <28 weeks gestation and experiencing socioeconomic disadvantage. We randomly allocated participants (one-to-one; computer-generated) to intervention (NFP plus existing services) or comparison (existing services) groups. Prespecified outcomes were prenatal substance exposure (reported previously); child injuries (primary), language, cognition and mental health (problem behaviour) by age two years; and subsequent pregnancies by 24 months postpartum. Research interviewers were masked. We used intention-to-treat analyses. (ClinicalTrials.gov, NCT01672060.) Results From 2013 to 2016 we enrolled 739 participants (368 NFP, 371 comparison) who had 737 children. Counts for child injury healthcare encounters [rate per 1,000 person-years or RPY] were similar for NFP (223 [RPY 316.17]) and comparison (223 [RPY 305.43]; rate difference 10.74, 95% CI -46.96, 68.44; rate ratio 1.03, 95% CI 0.78, 1.38). Maternal-reported language scores (mean, M [SD]) were statistically significantly higher for NFP (313.46 [195.96]) than comparison (282.77 [188.15]; mean difference [MD] 31.33, 95% CI 0.96, 61.71). Maternal-reported problem-behaviour scores (M [SD]) were statistically significantly lower for NFP (52.18 [9.19]) than comparison (54.42 [9.02]; MD -2.19, 95% CI 3.62, 0.75). Subsequent pregnancy counts were similar (NFP 115 [RPY 230.69] and comparison 117 [RPY 227.29]; rate difference 3.40, 95% CI -55.54, 62.34; hazard ratio 1.01, 95% CI 0.79, 1.29). We observed no unanticipated adverse events. Conclusions NFP did not reduce child injuries or subsequent maternal pregnancies but did improve maternal-reported child language and mental health (problem behaviour) at age two years. Follow-up of long-term outcomes is warranted given that further benefits may emerge across childhood and adolescence. En ligne : https://doi.org/10.1111/jcpp.13846 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=526 Psychophysiological influences on personality trajectories in adolescent females exposed to child maltreatment / Raha HASSAN in Development and Psychopathology, 32-4 (October 2020)
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[article]
Titre : Psychophysiological influences on personality trajectories in adolescent females exposed to child maltreatment Type de document : texte imprimé Auteurs : Raha HASSAN, Auteur ; Harriet L. MACMILLAN, Auteur ; Masako TANAKA, Auteur ; Louis A. SCHMIDT, Auteur Article en page(s) : p.1390-1401 Langues : Anglais (eng) Mots-clés : Eeg child maltreatment extraversion neuroticism respiratory sinus arrhythmia Index. décimale : PER Périodiques Résumé : Although child maltreatment is a major public health concern, which adversely affects psychological and physical development, we know relatively little concerning psychophysiological and personality factors that may modify risk in children exposed to maltreatment. Using a three-wave, short-term prospective design, we examined the influence of individual differences in two disparate psychophysiological measures of risk (i.e., resting frontal brain electrical activity and respiratory sinus arrhythmia) on the trajectories of extraversion and neuroticism in a sample of female adolescents (N = 55; M age = 14.02 years) exposed to child maltreatment. Adolescents exposed to child maltreatment with relatively higher left frontal absolute alpha power (i.e., lower brain activity) at rest exhibited increasing trajectories of extraversion, and adolescents exposed to child maltreatment with relatively lower respiratory sinus arrhythmia at rest displayed increasing trajectories of neuroticism over 1 year. Individual differences in psychophysiological measures indexing resting central and peripheral nervous system activity may therefore differentially influence personality characteristics in adolescent females exposed to child maltreatment. En ligne : http://dx.doi.org/10.1017/s0954579419001342 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433
in Development and Psychopathology > 32-4 (October 2020) . - p.1390-1401[article] Psychophysiological influences on personality trajectories in adolescent females exposed to child maltreatment [texte imprimé] / Raha HASSAN, Auteur ; Harriet L. MACMILLAN, Auteur ; Masako TANAKA, Auteur ; Louis A. SCHMIDT, Auteur . - p.1390-1401.
Langues : Anglais (eng)
in Development and Psychopathology > 32-4 (October 2020) . - p.1390-1401
Mots-clés : Eeg child maltreatment extraversion neuroticism respiratory sinus arrhythmia Index. décimale : PER Périodiques Résumé : Although child maltreatment is a major public health concern, which adversely affects psychological and physical development, we know relatively little concerning psychophysiological and personality factors that may modify risk in children exposed to maltreatment. Using a three-wave, short-term prospective design, we examined the influence of individual differences in two disparate psychophysiological measures of risk (i.e., resting frontal brain electrical activity and respiratory sinus arrhythmia) on the trajectories of extraversion and neuroticism in a sample of female adolescents (N = 55; M age = 14.02 years) exposed to child maltreatment. Adolescents exposed to child maltreatment with relatively higher left frontal absolute alpha power (i.e., lower brain activity) at rest exhibited increasing trajectories of extraversion, and adolescents exposed to child maltreatment with relatively lower respiratory sinus arrhythmia at rest displayed increasing trajectories of neuroticism over 1 year. Individual differences in psychophysiological measures indexing resting central and peripheral nervous system activity may therefore differentially influence personality characteristics in adolescent females exposed to child maltreatment. En ligne : http://dx.doi.org/10.1017/s0954579419001342 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

