Autistic behavior in boys with fragile X syndrome: social approach and HPA-axis dysfunction / Jane E. ROBERTS in Journal of Neurodevelopmental Disorders, 1-4 (December 2009)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 1-4 (December 2009) . - p.283-91 Titre : Autistic behavior in boys with fragile X syndrome: social approach and HPA-axis dysfunction Type de document : texte imprimé Auteurs : Jane E. ROBERTS, Auteur ; Megan A. CLARKE, Auteur ; Kaitlyn ALCORN, Auteur ; John C. CARTER, Auteur ; Anna C. LONG, Auteur ; Walter E. KAUFMANN, Auteur Article en page(s) : p.283-91 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The primary goal of this study was to examine environmental and neuroendocrine factors that convey increased risk for elevated autistic behavior in boys with Fragile X syndrome (FXS). This study involves three related analyses: (1) examination of multiple dimensions of social approach behaviors and how they vary over time, (2) investigation of mean levels and modulation of salivary cortisol levels in response to social interaction, and (3) examination of the relationship of social approach and autistic behaviors to salivary cortisol. Poor social approach and elevated baseline and regulation cortisol are discernible traits that distinguish boys with FXS and ASD from boys with FXS only and from typically developing boys. In addition, blunted cortisol change is associated with increased severity of autistic behaviors only within the FXS and ASD group. Boys with FXS and ASD have distinct behavioral and neuroendocrine profiles that differentiate them from those with FXS alone and typically developing boys. En ligne : http://dx.doi.org/10.1007/s11689-009-9028-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=342 [article] Autistic behavior in boys with fragile X syndrome: social approach and HPA-axis dysfunction [texte imprimé] / Jane E. ROBERTS, Auteur ; Megan A. CLARKE, Auteur ; Kaitlyn ALCORN, Auteur ; John C. CARTER, Auteur ; Anna C. LONG, Auteur ; Walter E. KAUFMANN, Auteur . - p.283-91. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 1-4 (December 2009) . - p.283-91 Index. décimale : PER Périodiques Résumé : The primary goal of this study was to examine environmental and neuroendocrine factors that convey increased risk for elevated autistic behavior in boys with Fragile X syndrome (FXS). This study involves three related analyses: (1) examination of multiple dimensions of social approach behaviors and how they vary over time, (2) investigation of mean levels and modulation of salivary cortisol levels in response to social interaction, and (3) examination of the relationship of social approach and autistic behaviors to salivary cortisol. Poor social approach and elevated baseline and regulation cortisol are discernible traits that distinguish boys with FXS and ASD from boys with FXS only and from typically developing boys. In addition, blunted cortisol change is associated with increased severity of autistic behaviors only within the FXS and ASD group. Boys with FXS and ASD have distinct behavioral and neuroendocrine profiles that differentiate them from those with FXS alone and typically developing boys. En ligne : http://dx.doi.org/10.1007/s11689-009-9028-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=342

Effortful control as a moderator of the relation between contextual risk factors and growth in adjustment problems / Liliana J. LENGUA in Development and Psychopathology, 20-2 (Spring 2008)  

Public ISBD [article]  inDevelopment and Psychopathology > 20-2 (Spring 2008) . - p.509-528 Titre : Effortful control as a moderator of the relation between contextual risk factors and growth in adjustment problems Type de document : texte imprimé Auteurs : Liliana J. LENGUA, Auteur ; Anna C. LONG, Auteur ; Nicole R. BUSH, Auteur ; Erica KOVACS, Auteur ; Anika M. TRANCIK, Auteur Année de publication : 2008 Article en page(s) : p.509-528 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Effortful control was examined as a moderator of the relations of three domains of contextual risk factors to growth in internalizing and externalizing problems in a community sample (N = 189) of children (8–12 years at Time 1). Socioeconomic, maternal, and environmental risk factors were examined as predictors of initial levels and growth in children's adjustment problems across 3 years. The effects of the risk factors depended on children's level of effortful control. For children lower in effortful control, socioeconomic risk was related to significantly higher initial levels of internalizing and externalizing problems and decreases over time. However, children lower in effortful control had higher levels of problems at all three time points than children higher in effortful control. Maternal risk was associated with increases in internalizing for children lower in effortful control, and environmental risk was related to increases in internalizing and externalizing problems for children lower in effortful control, but not those higher in effortful control. Children who were lower in effortful control appeared to experience more adverse effects of contextual risk than those higher in effortful control, suggesting that interventions aimed at improving children's effortful control might serve to protect children from increased risk of adjustment problems associated with contextual risk factors. En ligne : http://dx.doi.org/10.1017/s0954579408000254 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=412 [article] Effortful control as a moderator of the relation between contextual risk factors and growth in adjustment problems [texte imprimé] / Liliana J. LENGUA, Auteur ; Anna C. LONG, Auteur ; Nicole R. BUSH, Auteur ; Erica KOVACS, Auteur ; Anika M. TRANCIK, Auteur . - 2008 . - p.509-528. Langues : Anglais (eng) in Development and Psychopathology > 20-2 (Spring 2008) . - p.509-528 Index. décimale : PER Périodiques Résumé : Effortful control was examined as a moderator of the relations of three domains of contextual risk factors to growth in internalizing and externalizing problems in a community sample (N = 189) of children (8–12 years at Time 1). Socioeconomic, maternal, and environmental risk factors were examined as predictors of initial levels and growth in children's adjustment problems across 3 years. The effects of the risk factors depended on children's level of effortful control. For children lower in effortful control, socioeconomic risk was related to significantly higher initial levels of internalizing and externalizing problems and decreases over time. However, children lower in effortful control had higher levels of problems at all three time points than children higher in effortful control. Maternal risk was associated with increases in internalizing for children lower in effortful control, and environmental risk was related to increases in internalizing and externalizing problems for children lower in effortful control, but not those higher in effortful control. Children who were lower in effortful control appeared to experience more adverse effects of contextual risk than those higher in effortful control, suggesting that interventions aimed at improving children's effortful control might serve to protect children from increased risk of adjustment problems associated with contextual risk factors. En ligne : http://dx.doi.org/10.1017/s0954579408000254 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=412

Pre-attack stress-load, appraisals, and coping in children's responses to the 9/11 terrorist attacks / Liliana J. LENGUA in Journal of Child Psychology and Psychiatry, 47-12 (December 2006)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 47-12 (December 2006) . - p.1219–1227 Titre : Pre-attack stress-load, appraisals, and coping in children's responses to the 9/11 terrorist attacks Type de document : texte imprimé Auteurs : Liliana J. LENGUA, Auteur ; Andrew N. MELTZOFF, Auteur ; Anna C. LONG, Auteur Année de publication : 2007 Article en page(s) : p.1219–1227 Langues : Anglais (eng) Mots-clés : PTS appraisal coping stress-load disaster Index. décimale : PER Périodiques Résumé : Background: Appraisal and coping following a disaster are important factors in children's post-traumatic stress (PTS) symptoms. However, little is known about predictors of disaster coping responses. This study examined stress-load, appraisals and coping styles measured prior to the September 11 terrorist attacks as predictors of 9/11-specific appraisals, coping and PTS. Methods: A community sample of children and parents (N = 143) participating in an ongoing study were interviewed by phone approximately 1 month following 9/11. Results: Pre-attack stress-load, appraisal and coping styles predicted children's 9/11-specific appraisals, coping, and PTS. 9/11-specific threat appraisals and avoidant coping predicted higher PTS and mediated the effects of pre-attack stress-load and threat appraisal. Conclusions: Pre-disaster stress-load, appraisal and coping styles predict disaster-specific appraisal and coping, which in turn, contribute to PTS. Coping interventions might mitigate PTS symptoms following a disaster. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01664.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=812 [article] Pre-attack stress-load, appraisals, and coping in children's responses to the 9/11 terrorist attacks [texte imprimé] / Liliana J. LENGUA, Auteur ; Andrew N. MELTZOFF, Auteur ; Anna C. LONG, Auteur . - 2007 . - p.1219–1227. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 47-12 (December 2006) . - p.1219–1227 Mots-clés : PTS appraisal coping stress-load disaster Index. décimale : PER Périodiques Résumé : Background: Appraisal and coping following a disaster are important factors in children's post-traumatic stress (PTS) symptoms. However, little is known about predictors of disaster coping responses. This study examined stress-load, appraisals and coping styles measured prior to the September 11 terrorist attacks as predictors of 9/11-specific appraisals, coping and PTS. Methods: A community sample of children and parents (N = 143) participating in an ongoing study were interviewed by phone approximately 1 month following 9/11. Results: Pre-attack stress-load, appraisal and coping styles predicted children's 9/11-specific appraisals, coping, and PTS. 9/11-specific threat appraisals and avoidant coping predicted higher PTS and mediated the effects of pre-attack stress-load and threat appraisal. Conclusions: Pre-disaster stress-load, appraisal and coping styles predict disaster-specific appraisal and coping, which in turn, contribute to PTS. Coping interventions might mitigate PTS symptoms following a disaster. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01664.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=812

Visual Attention and Autistic Behavior in Infants with Fragile X Syndrome / Jane E. ROBERTS in Journal of Autism and Developmental Disorders, 42-6 (June 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-6 (June 2012) . - p.937-946 Titre : Visual Attention and Autistic Behavior in Infants with Fragile X Syndrome Type de document : texte imprimé Auteurs : Jane E. ROBERTS, Auteur ; Deborah D. HATTON, Auteur ; Anna C. LONG, Auteur ; Vittoria ANELLO, Auteur ; John COLOMBO, Auteur Année de publication : 2012 Article en page(s) : p.937-946 Langues : Anglais (eng) Mots-clés : Fragile X  Autism  Early detection  Heart rate  Visual attention  High-risk infants Index. décimale : PER Périodiques Résumé : Aberrant attention is a core feature of fragile X syndrome (FXS), however, little is known regarding the developmental trajectory and underlying physiological processes of attention deficits in FXS. Atypical visual attention is an early emerging and robust indictor of autism in idiopathic (non-FXS) autism. Using a biobehavioral approach with gaze direction and heart activity, we examined visual attention in infants with FXS at 9, 12, and 18 months of age with a cross-sectional comparison to 12-month-old typically developing infants. Analyses revealed lower HR variability, shallower HR decelerations, and prolonged look durations in 12-month old infants with FXS compared to typical controls. Look duration and increased latency to disengage attention were correlated with severity of autistic behavior but not mental age. En ligne : http://dx.doi.org/10.1007/s10803-011-1316-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=156 [article] Visual Attention and Autistic Behavior in Infants with Fragile X Syndrome [texte imprimé] / Jane E. ROBERTS, Auteur ; Deborah D. HATTON, Auteur ; Anna C. LONG, Auteur ; Vittoria ANELLO, Auteur ; John COLOMBO, Auteur . - 2012 . - p.937-946. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-6 (June 2012) . - p.937-946 Mots-clés : Fragile X  Autism  Early detection  Heart rate  Visual attention  High-risk infants Index. décimale : PER Périodiques Résumé : Aberrant attention is a core feature of fragile X syndrome (FXS), however, little is known regarding the developmental trajectory and underlying physiological processes of attention deficits in FXS. Atypical visual attention is an early emerging and robust indictor of autism in idiopathic (non-FXS) autism. Using a biobehavioral approach with gaze direction and heart activity, we examined visual attention in infants with FXS at 9, 12, and 18 months of age with a cross-sectional comparison to 12-month-old typically developing infants. Analyses revealed lower HR variability, shallower HR decelerations, and prolonged look durations in 12-month old infants with FXS compared to typical controls. Look duration and increased latency to disengage attention were correlated with severity of autistic behavior but not mental age. En ligne : http://dx.doi.org/10.1007/s10803-011-1316-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=156

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