Characteristics of psychiatric emergency department use among privately insured adolescents with autism spectrum disorder / Luke G. KALB in Autism, 23-3 (April 2019)  

Public ISBD [article]  inAutism > 23-3 (April 2019) . - p.566-573 Titre : Characteristics of psychiatric emergency department use among privately insured adolescents with autism spectrum disorder Type de document : texte imprimé Auteurs : Luke G. KALB, Auteur ; Elizabeth A. STUART, Auteur ; Roma A. VASA, Auteur Article en page(s) : p.566-573 Langues : Anglais (eng) Mots-clés : attention deficit hyperactivity disorder  autism spectrum disorders  crisis  emergency  health services Index. décimale : PER Périodiques Résumé : This study examined differences in the rates of psychiatric-related emergency department visits among adolescents with autism spectrum disorder, adolescents with attention deficit hyperactivity disorder, and adolescents without autism spectrum disorder or attention deficit hyperactivity disorder. Additional outcomes included emergency department recidivism, probability of psychiatric hospitalization after the emergency department visit, and receipt of outpatient mental health services before and after the emergency department visit. Data came from privately insured adolescents, aged 12-17 years, with autism spectrum disorder (N = 46,323), attention deficit hyperactivity disorder (N = 408,066), and neither diagnosis (N = 2,330,332), enrolled in the 2010-2013 MarketScan Commercial Claims Database. Adolescents with autism spectrum disorder had an increased rate of psychiatric emergency department visits compared to adolescents with attention deficit hyperactivity disorder (IRR = 2.0, 95% confidence interval: 1.9, 2.1) and adolescents with neither diagnosis (IRR = 9.9, 95% confidence interval: 9.4, 10.4). Compared to the other groups, adolescents with autism spectrum disorder also had an increased probability of emergency department recidivism, psychiatric hospitalization after the emergency department visit, and receipt of outpatient care before and after the visit (all p < 0.001). Further research is required to understand whether these findings extend to youth with other neurodevelopmental disorders, particularly those who are publicly insured. En ligne : http://dx.doi.org/10.1177/1362361317749951 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392 [article] Characteristics of psychiatric emergency department use among privately insured adolescents with autism spectrum disorder [texte imprimé] / Luke G. KALB, Auteur ; Elizabeth A. STUART, Auteur ; Roma A. VASA, Auteur . - p.566-573. Langues : Anglais (eng) in Autism > 23-3 (April 2019) . - p.566-573 Mots-clés : attention deficit hyperactivity disorder  autism spectrum disorders  crisis  emergency  health services Index. décimale : PER Périodiques Résumé : This study examined differences in the rates of psychiatric-related emergency department visits among adolescents with autism spectrum disorder, adolescents with attention deficit hyperactivity disorder, and adolescents without autism spectrum disorder or attention deficit hyperactivity disorder. Additional outcomes included emergency department recidivism, probability of psychiatric hospitalization after the emergency department visit, and receipt of outpatient mental health services before and after the emergency department visit. Data came from privately insured adolescents, aged 12-17 years, with autism spectrum disorder (N = 46,323), attention deficit hyperactivity disorder (N = 408,066), and neither diagnosis (N = 2,330,332), enrolled in the 2010-2013 MarketScan Commercial Claims Database. Adolescents with autism spectrum disorder had an increased rate of psychiatric emergency department visits compared to adolescents with attention deficit hyperactivity disorder (IRR = 2.0, 95% confidence interval: 1.9, 2.1) and adolescents with neither diagnosis (IRR = 9.9, 95% confidence interval: 9.4, 10.4). Compared to the other groups, adolescents with autism spectrum disorder also had an increased probability of emergency department recidivism, psychiatric hospitalization after the emergency department visit, and receipt of outpatient care before and after the visit (all p < 0.001). Further research is required to understand whether these findings extend to youth with other neurodevelopmental disorders, particularly those who are publicly insured. En ligne : http://dx.doi.org/10.1177/1362361317749951 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392

Cord and Early Childhood Plasma Adiponectin Levels and Autism Risk: A Prospective Birth Cohort Study / Ramkripa RAGHAVAN in Journal of Autism and Developmental Disorders, 49-1 (January 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-1 (January 2019) . - p.173-184 Titre : Cord and Early Childhood Plasma Adiponectin Levels and Autism Risk: A Prospective Birth Cohort Study Type de document : texte imprimé Auteurs : Ramkripa RAGHAVAN, Auteur ; M. Daniele FALLIN, Auteur ; Xiumei HONG, Auteur ; Guoying WANG, Auteur ; Yuelong JI, Auteur ; Elizabeth A. STUART, Auteur ; David PAIGE, Auteur ; Xiaoming WANG, Auteur Article en page(s) : p.173-184 Langues : Anglais (eng) Mots-clés : Adiponectin  Autism  Cytokines  Preterm birth Index. décimale : PER Périodiques Résumé : Emerging research suggests that adiponectin, a cytokine produced by adipose tissue, may be implicated in ASD. In this prospective birth cohort study (n = 847), we assessed the association between cord, early childhood plasma adiponectin and the risk of developing ASD. ASD was defined based on ICD codes of physician diagnosis. Cord adiponectin levels were inversely associated with ASD risk (aOR 0.50; 95% CI 0.33, 0.77), independent of preterm birth, early childhood adiponectin and other known ASD risk factors. Early childhood adiponectin, assessed prior to ASD diagnosis, was associated with lower risk of ASD, which attenuated after adjusting for cord adiponectin, indicating the relative importance of cord adiponectin in ASD risk. Further research is warranted to confirm our findings and elucidate biological mechanisms. En ligne : http://dx.doi.org/10.1007/s10803-018-3688-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=376 [article] Cord and Early Childhood Plasma Adiponectin Levels and Autism Risk: A Prospective Birth Cohort Study [texte imprimé] / Ramkripa RAGHAVAN, Auteur ; M. Daniele FALLIN, Auteur ; Xiumei HONG, Auteur ; Guoying WANG, Auteur ; Yuelong JI, Auteur ; Elizabeth A. STUART, Auteur ; David PAIGE, Auteur ; Xiaoming WANG, Auteur . - p.173-184. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-1 (January 2019) . - p.173-184 Mots-clés : Adiponectin  Autism  Cytokines  Preterm birth Index. décimale : PER Périodiques Résumé : Emerging research suggests that adiponectin, a cytokine produced by adipose tissue, may be implicated in ASD. In this prospective birth cohort study (n = 847), we assessed the association between cord, early childhood plasma adiponectin and the risk of developing ASD. ASD was defined based on ICD codes of physician diagnosis. Cord adiponectin levels were inversely associated with ASD risk (aOR 0.50; 95% CI 0.33, 0.77), independent of preterm birth, early childhood adiponectin and other known ASD risk factors. Early childhood adiponectin, assessed prior to ASD diagnosis, was associated with lower risk of ASD, which attenuated after adjusting for cord adiponectin, indicating the relative importance of cord adiponectin in ASD risk. Further research is warranted to confirm our findings and elucidate biological mechanisms. En ligne : http://dx.doi.org/10.1007/s10803-018-3688-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=376

Factors Affecting Age at Initial Autism Spectrum Disorder Diagnosis in a National Survey / Rebecca E. ROSENBERG in Autism Research and Treatment, (May 2011)  

Public ISBD [article]  inAutism Research and Treatment > (May 2011) . - 11 p. Titre : Factors Affecting Age at Initial Autism Spectrum Disorder Diagnosis in a National Survey Type de document : texte imprimé Auteurs : Rebecca E. ROSENBERG, Auteur ; Rebecca LANDA, Auteur ; J. Kiely LAW, Auteur ; Elizabeth A. STUART, Auteur ; Paul A. LAW, Auteur Année de publication : 2011 Article en page(s) : 11 p. Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Entry into early intervention depends on both age of first parent concern (AOC) and age at initial autism spectrum disorder (ASD) diagnosis (AOD). Using data collected from a national online registry from 6214 children diagnosed with an ASD between 1994 and 2010 in the US, we analyzed the effect of individual, family, and geographic covariates on AOC and AOD in a multivariate linear regression model with random effects. Overall, no single modifiable factor associated with AOC or AOD emerged but cumulative variation in certain individual- and family-based features, as well as some geographic factors, all contribute to AOC and AOD variation. A multipronged strategy is needed for targeted education and awareness campaigns to maximize outcomes and decrease disparities in ASD care. En ligne : http://dx.doi.org/10.1155/2011/874619 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=141 [article] Factors Affecting Age at Initial Autism Spectrum Disorder Diagnosis in a National Survey [texte imprimé] / Rebecca E. ROSENBERG, Auteur ; Rebecca LANDA, Auteur ; J. Kiely LAW, Auteur ; Elizabeth A. STUART, Auteur ; Paul A. LAW, Auteur . - 2011 . - 11 p. Langues : Anglais (eng) in Autism Research and Treatment > (May 2011) . - 11 p. Index. décimale : PER Périodiques Résumé : Entry into early intervention depends on both age of first parent concern (AOC) and age at initial autism spectrum disorder (ASD) diagnosis (AOD). Using data collected from a national online registry from 6214 children diagnosed with an ASD between 1994 and 2010 in the US, we analyzed the effect of individual, family, and geographic covariates on AOC and AOD in a multivariate linear regression model with random effects. Overall, no single modifiable factor associated with AOC or AOD emerged but cumulative variation in certain individual- and family-based features, as well as some geographic factors, all contribute to AOC and AOD variation. A multipronged strategy is needed for targeted education and awareness campaigns to maximize outcomes and decrease disparities in ASD care. En ligne : http://dx.doi.org/10.1155/2011/874619 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=141

Intervention targeting development of socially synchronous engagement in toddlers with autism spectrum disorder: a randomized controlled trial / Rebecca LANDA in Journal of Child Psychology and Psychiatry, 52-1 (January 2011)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 52-1 (January 2011) . - p. 13-21 Titre : Intervention targeting development of socially synchronous engagement in toddlers with autism spectrum disorder: a randomized controlled trial Type de document : texte imprimé Auteurs : Rebecca LANDA, Auteur ; Katherine C. HOLMAN, Auteur ; Allison H. O'NEILL, Auteur ; Elizabeth A. STUART, Auteur Année de publication : 2011 Article en page(s) : p. 13-21 Langues : Anglais (eng) Mots-clés : Autistic disorder  intervention Index. décimale : PER Périodiques Résumé : Background:  Social and communication impairments are core deficits and prognostic indicators of autism. We evaluated the impact of supplementing a comprehensive intervention with a curriculum targeting socially synchronous behavior on social outcomes of toddlers with autism spectrum disorders (ASD). Methods:  Fifty toddlers with ASD, ages 21 to 33 months, were randomized to one of two six-month interventions: Interpersonal Synchrony or Non-Interpersonal Synchrony. The interventions provided identical intensity (10 hours per week in classroom), student-to-teacher ratio, schedule, home-based parent training (1.5 hours per month), parent education (38 hours), and instructional strategies, except the Interpersonal Synchrony condition provided a supplementary curriculum targeting socially engaged imitation, joint attention, and affect sharing; measures of these were primary outcomes. Assessments were conducted pre-intervention, immediately post-intervention, and, to assess maintenance, at six-month follow-up. Random effects models were used to examine differences between groups over time. Secondary analyses examined gains in expressive language and nonverbal cognition, and time effects during the intervention and follow-up periods. Results:  A significant treatment effect was found for socially engaged imitation (p = .02), with more than doubling (17% to 42%) of imitated acts paired with eye contact in the Interpersonal Synchrony group after the intervention. This skill was generalized to unfamiliar contexts and maintained through follow-up. Similar gains were observed for initiation of joint attention and shared positive affect, but between-group differences did not reach statistical significance. A significant time effect was found for all outcomes (p < .001); greatest change occurred during the intervention period, particularly in the Interpersonal Synchrony group. Conclusions:  This is the first ASD randomized trial involving toddlers to identify an active ingredient for enhancing socially engaged imitation. Adding social engagement targets to intervention improves short-term outcome at no additional cost to the intervention. The social, language, and cognitive gains in our participants provide evidence for plasticity of these developmental systems in toddlers with ASD. http://www.clinicaltrials.gov/ct2/show/NCT00106210 term = landa&rank = 3. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02288.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=113 [article] Intervention targeting development of socially synchronous engagement in toddlers with autism spectrum disorder: a randomized controlled trial [texte imprimé] / Rebecca LANDA, Auteur ; Katherine C. HOLMAN, Auteur ; Allison H. O'NEILL, Auteur ; Elizabeth A. STUART, Auteur . - 2011 . - p. 13-21. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 52-1 (January 2011) . - p. 13-21 Mots-clés : Autistic disorder  intervention Index. décimale : PER Périodiques Résumé : Background:  Social and communication impairments are core deficits and prognostic indicators of autism. We evaluated the impact of supplementing a comprehensive intervention with a curriculum targeting socially synchronous behavior on social outcomes of toddlers with autism spectrum disorders (ASD). Methods:  Fifty toddlers with ASD, ages 21 to 33 months, were randomized to one of two six-month interventions: Interpersonal Synchrony or Non-Interpersonal Synchrony. The interventions provided identical intensity (10 hours per week in classroom), student-to-teacher ratio, schedule, home-based parent training (1.5 hours per month), parent education (38 hours), and instructional strategies, except the Interpersonal Synchrony condition provided a supplementary curriculum targeting socially engaged imitation, joint attention, and affect sharing; measures of these were primary outcomes. Assessments were conducted pre-intervention, immediately post-intervention, and, to assess maintenance, at six-month follow-up. Random effects models were used to examine differences between groups over time. Secondary analyses examined gains in expressive language and nonverbal cognition, and time effects during the intervention and follow-up periods. Results:  A significant treatment effect was found for socially engaged imitation (p = .02), with more than doubling (17% to 42%) of imitated acts paired with eye contact in the Interpersonal Synchrony group after the intervention. This skill was generalized to unfamiliar contexts and maintained through follow-up. Similar gains were observed for initiation of joint attention and shared positive affect, but between-group differences did not reach statistical significance. A significant time effect was found for all outcomes (p < .001); greatest change occurred during the intervention period, particularly in the Interpersonal Synchrony group. Conclusions:  This is the first ASD randomized trial involving toddlers to identify an active ingredient for enhancing socially engaged imitation. Adding social engagement targets to intervention improves short-term outcome at no additional cost to the intervention. The social, language, and cognitive gains in our participants provide evidence for plasticity of these developmental systems in toddlers with ASD. http://www.clinicaltrials.gov/ct2/show/NCT00106210 term = landa&rank = 3. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02288.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=113

Latent class analysis of early developmental trajectory in baby siblings of children with autism / Rebecca LANDA in Journal of Child Psychology and Psychiatry, 53-9 (September 2012)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 53-9 (September 2012) . - p.986-96 Titre : Latent class analysis of early developmental trajectory in baby siblings of children with autism Type de document : texte imprimé Auteurs : Rebecca LANDA, Auteur ; Alden L. GROSS, Auteur ; Elizabeth A. STUART, Auteur ; Margaret L. BAUMAN, Auteur Année de publication : 2012 Article en page(s) : p.986-96 Langues : Anglais (eng) Mots-clés : Autism  trajectories  broader autism phenotype Index. décimale : PER Périodiques Résumé : Background:  Siblings of children with autism (sibs-A) are at increased genetic risk for autism spectrum disorders (ASD) and milder impairments. To elucidate diversity and contour of early developmental trajectories exhibited by sibs-A, regardless of diagnostic classification, latent class modeling was used. Methods:  Sibs-A (N = 204) were assessed with the Mullen Scales of Early Learning from age 6 to 36 months. Mullen T scores served as dependent variables. Outcome classifications at age 36 months included: ASD (N = 52); non-ASD social/communication delay (broader autism phenotype; BAP; N = 31); and unaffected (N = 121). Child-specific patterns of performance were studied using latent class growth analysis. Latent class membership was then related to diagnostic outcome through estimation of within-class proportions of children assigned to each diagnostic classification. Results:  A 4-class model was favored. Class 1 represented accelerated development and consisted of 25.7% of the sample, primarily unaffected children. Class 2 (40.0% of the sample), was characterized by normative development with above-average nonverbal cognitive outcome. Class 3 (22.3% of the sample) was characterized by receptive language, and gross and fine motor delay. Class 4 (12.0% of the sample), was characterized by widespread delayed skill acquisition, reflected by declining trajectories. Children with an outcome diagnosis of ASD were spread across Classes 2, 3, and 4. Conclusions:  Results support a category of ASD that involves slowing in early non-social development. Receptive language and motor development is vulnerable to early delay in sibs-A with and without ASD outcomes. Non-ASD sibs-A are largely distributed across classes depicting average or accelerated development. Developmental trajectories of motor, language, and cognition appear independent of communication and social delays in non-ASD sibs-A. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2012.02558.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=179 [article] Latent class analysis of early developmental trajectory in baby siblings of children with autism [texte imprimé] / Rebecca LANDA, Auteur ; Alden L. GROSS, Auteur ; Elizabeth A. STUART, Auteur ; Margaret L. BAUMAN, Auteur . - 2012 . - p.986-96. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 53-9 (September 2012) . - p.986-96 Mots-clés : Autism  trajectories  broader autism phenotype Index. décimale : PER Périodiques Résumé : Background:  Siblings of children with autism (sibs-A) are at increased genetic risk for autism spectrum disorders (ASD) and milder impairments. To elucidate diversity and contour of early developmental trajectories exhibited by sibs-A, regardless of diagnostic classification, latent class modeling was used. Methods:  Sibs-A (N = 204) were assessed with the Mullen Scales of Early Learning from age 6 to 36 months. Mullen T scores served as dependent variables. Outcome classifications at age 36 months included: ASD (N = 52); non-ASD social/communication delay (broader autism phenotype; BAP; N = 31); and unaffected (N = 121). Child-specific patterns of performance were studied using latent class growth analysis. Latent class membership was then related to diagnostic outcome through estimation of within-class proportions of children assigned to each diagnostic classification. Results:  A 4-class model was favored. Class 1 represented accelerated development and consisted of 25.7% of the sample, primarily unaffected children. Class 2 (40.0% of the sample), was characterized by normative development with above-average nonverbal cognitive outcome. Class 3 (22.3% of the sample) was characterized by receptive language, and gross and fine motor delay. Class 4 (12.0% of the sample), was characterized by widespread delayed skill acquisition, reflected by declining trajectories. Children with an outcome diagnosis of ASD were spread across Classes 2, 3, and 4. Conclusions:  Results support a category of ASD that involves slowing in early non-social development. Receptive language and motor development is vulnerable to early delay in sibs-A with and without ASD outcomes. Non-ASD sibs-A are largely distributed across classes depicting average or accelerated development. Developmental trajectories of motor, language, and cognition appear independent of communication and social delays in non-ASD sibs-A. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2012.02558.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=179

Prenatal exposure to fever is associated with autism spectrum disorder in the boston birth cohort / Martha BRUCATO in Autism Research, 10-11 (November 2017)  

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Psychological distress among caregivers raising a child with autism spectrum disorder during the COVID-19 pandemic / Luke G. KALB in Autism Research, 14-10 (October 2021)  

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Relationship Status Among Parents of Children with Autism Spectrum Disorders: A Population-Based Study / Brian FREEDMAN in Journal of Autism and Developmental Disorders, 42-4 (April 2012)  

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The Association Between Mental Health, Stress, and Coping Supports in Mothers of Children with Autism Spectrum Disorders / Benjamin ZABLOTSKY in Journal of Autism and Developmental Disorders, 43-6 (June 2013)  

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