Default mode network in young male adults with autism spectrum disorder: relationship with autism spectrum traits / Minyoung JUNG in Molecular Autism, (June 2014)  

Public ISBD [article]  inMolecular Autism > (June 2014) . - p.1-11 Titre : Default mode network in young male adults with autism spectrum disorder: relationship with autism spectrum traits Type de document : Texte imprimé et/ou numérique Auteurs : Minyoung JUNG, Auteur ; Hirotaka KOSAKA, Auteur ; Daisuke N. SAITO, Auteur ; Makoto ISHITOBI, Auteur ; Tomoyo MORITA, Auteur ; Keisuke INOHARA, Auteur ; Mizuki ASANO, Auteur ; Sumiyoshi ARAI, Auteur ; Toshio MUNESUE, Auteur ; Akemi TOMODA, Auteur ; Yuji WADA, Auteur ; Norihiro SADATO, Auteur ; Hidehiko OKAZAWA, Auteur ; Tetsuya IIDAKA, Auteur Article en page(s) : p.1-11 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism spectrum traits are postulated to lie on a continuum that extends between individuals with autism and individuals with typical development (TD). Social cognition properties that are deeply associated with autism spectrum traits have been linked to functional connectivity between regions within the brain’s default mode network (DMN). Previous studies have shown that the resting-state functional connectivities (rs-FCs) of DMN are low and show negative correlation with the level of autism spectrum traits in individuals with autism spectrum disorder (ASD). However, it is unclear whether individual differences of autism spectrum traits are associated with the strength of rs-FCs of DMN in participants including the general population. En ligne : http://dx.doi.org/10.1186/2040-2392-5-35 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276 [article] Default mode network in young male adults with autism spectrum disorder: relationship with autism spectrum traits [Texte imprimé et/ou numérique] / Minyoung JUNG, Auteur ; Hirotaka KOSAKA, Auteur ; Daisuke N. SAITO, Auteur ; Makoto ISHITOBI, Auteur ; Tomoyo MORITA, Auteur ; Keisuke INOHARA, Auteur ; Mizuki ASANO, Auteur ; Sumiyoshi ARAI, Auteur ; Toshio MUNESUE, Auteur ; Akemi TOMODA, Auteur ; Yuji WADA, Auteur ; Norihiro SADATO, Auteur ; Hidehiko OKAZAWA, Auteur ; Tetsuya IIDAKA, Auteur . - p.1-11. Langues : Anglais (eng) in Molecular Autism > (June 2014) . - p.1-11 Index. décimale : PER Périodiques Résumé : Autism spectrum traits are postulated to lie on a continuum that extends between individuals with autism and individuals with typical development (TD). Social cognition properties that are deeply associated with autism spectrum traits have been linked to functional connectivity between regions within the brain’s default mode network (DMN). Previous studies have shown that the resting-state functional connectivities (rs-FCs) of DMN are low and show negative correlation with the level of autism spectrum traits in individuals with autism spectrum disorder (ASD). However, it is unclear whether individual differences of autism spectrum traits are associated with the strength of rs-FCs of DMN in participants including the general population. En ligne : http://dx.doi.org/10.1186/2040-2392-5-35 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276

Differential amygdala response to lower face in patients with autistic spectrum disorders: An fMRI study / Makoto ISHITOBI in Research in Autism Spectrum Disorders, 5-2 (April-June 2011)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 5-2 (April-June 2011) . - p.910-919 Titre : Differential amygdala response to lower face in patients with autistic spectrum disorders: An fMRI study Type de document : Texte imprimé et/ou numérique Auteurs : Makoto ISHITOBI, Auteur ; Hirotaka KOSAKA, Auteur ; Masao OMORI, Auteur ; Yukiko MATSUMURA, Auteur ; Toshio MUNESUE, Auteur ; Kimiko MIZUKAMI, Auteur ; Tomohiro SHIMOYAMA, Auteur ; Tetsuhito MURATA, Auteur ; Norihiro SADATO, Auteur ; Hidehiko OKAZAWA, Auteur ; Yuji WADA, Auteur Année de publication : 2011 Article en page(s) : p.910-919 Langues : Anglais (eng) Mots-clés : Autistic spectrum disorders (ASD)  Pervasive developmental disorders (PDD)  Amygdala  Mouth  Salience  Eye gaze Index. décimale : PER Périodiques Résumé : Much functional neuroimaging evidence indicates that autistic spectrum disorders (ASD) demonstrate marked brain abnormalities in face processing. Most of these findings were obtained from studies using tasks related to whole faces. However, individuals with ASD tend to rely more on individual parts of the face for identification than on the overall configuration. Therefore, this neuroimaging evidence might reflect differential visual attention systems in face recognition. It was hypothesized that differential brain function is shown between ASD and control participants with face recognition tasks presenting parts of faces separately. Nine adults with high-functioning ASD and 24 age-matched normal comparison participants were studied using a 3T-MR scanner. We investigated brain activation when processing whole faces and parts of faces displaying positive or negative expressions. The control group showed bilateral amygdalae activation to the whole face, but not to parts of the face. The ASD group showed bilateral amygdalae activation to the lower face (mainly mouth region), but not to the whole face and upper face (mainly eye region). These findings suggest that differential amygdala function for face processing exists in ASD. This aberrant amygdala function might cause abnormalities in gaze processing or recognition of emotional expressions, shown clinically in ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2010.10.005 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=114 [article] Differential amygdala response to lower face in patients with autistic spectrum disorders: An fMRI study [Texte imprimé et/ou numérique] / Makoto ISHITOBI, Auteur ; Hirotaka KOSAKA, Auteur ; Masao OMORI, Auteur ; Yukiko MATSUMURA, Auteur ; Toshio MUNESUE, Auteur ; Kimiko MIZUKAMI, Auteur ; Tomohiro SHIMOYAMA, Auteur ; Tetsuhito MURATA, Auteur ; Norihiro SADATO, Auteur ; Hidehiko OKAZAWA, Auteur ; Yuji WADA, Auteur . - 2011 . - p.910-919. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 5-2 (April-June 2011) . - p.910-919 Mots-clés : Autistic spectrum disorders (ASD)  Pervasive developmental disorders (PDD)  Amygdala  Mouth  Salience  Eye gaze Index. décimale : PER Périodiques Résumé : Much functional neuroimaging evidence indicates that autistic spectrum disorders (ASD) demonstrate marked brain abnormalities in face processing. Most of these findings were obtained from studies using tasks related to whole faces. However, individuals with ASD tend to rely more on individual parts of the face for identification than on the overall configuration. Therefore, this neuroimaging evidence might reflect differential visual attention systems in face recognition. It was hypothesized that differential brain function is shown between ASD and control participants with face recognition tasks presenting parts of faces separately. Nine adults with high-functioning ASD and 24 age-matched normal comparison participants were studied using a 3T-MR scanner. We investigated brain activation when processing whole faces and parts of faces displaying positive or negative expressions. The control group showed bilateral amygdalae activation to the whole face, but not to parts of the face. The ASD group showed bilateral amygdalae activation to the lower face (mainly mouth region), but not to the whole face and upper face (mainly eye region). These findings suggest that differential amygdala function for face processing exists in ASD. This aberrant amygdala function might cause abnormalities in gaze processing or recognition of emotional expressions, shown clinically in ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2010.10.005 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=114

Neural correlates of emotion processing during observed self-face recognition in individuals with autism spectrum disorders / Tomoyo MORITA in Research in Autism Spectrum Disorders, 26 (June 2016)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 26 (June 2016) . - p.16-32 Titre : Neural correlates of emotion processing during observed self-face recognition in individuals with autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Tomoyo MORITA, Auteur ; Hirotaka KOSAKA, Auteur ; Daisuke N. SAITO, Auteur ; Takeshi FUJII, Auteur ; Makoto ISHITOBI, Auteur ; Toshio MUNESUE, Auteur ; Keisuke INOHARA, Auteur ; Hidehiko OKAZAWA, Auteur ; Ryusuke KAKIGI, Auteur ; Norihiro SADATO, Auteur Article en page(s) : p.16-32 Langues : Anglais (eng) Mots-clés : Anterior cingulate cortex  Anterior insula  Autism spectrum disorder (ASD)  Being observed  Embarrassment  Functional magnetic resonance imaging  Self-face Index. décimale : PER Périodiques Résumé : When exposed to self-face images, individuals often experience embarrassment, which is enhanced by being observed. This self-evaluative emotion is related to activity in the right anterior insula and the functional connectivity between the anterior cingulate and prefrontal cortices. Coupling between cognitive evaluation of self-face images and emotional response to them (cognitive–emotional coupling) is weaker in individuals with autism spectrum disorder (ASD), in parallel with reduced activity of the right insula. To determine whether self-evaluative emotions of individuals with ASD are less strongly impacted by observation, we conducted functional MRI in 14 adult men with ASD and 18 age-matched control men while the participants viewed self-face images. Increased embarrassment upon observation was positively correlated with increased activity in the right anterior insula in the control group, but not in the ASD group. In addition, awareness of being observed enhanced cognitive–emotional coupling in the controls but not in the ASD group. The coupling was correlated with the functional connectivity between the anterior cingulate and medial prefrontal cortices. These results suggest that the reduced impact of observation on embarrassment induced by self-face images in individuals with ASD is related to impairment in the right anterior insula, which is involved in creating subjective feelings, and the anterior cingulate cortex, which acts as a hub for integrating information from others during self-face evaluation. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.02.011 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=285 [article] Neural correlates of emotion processing during observed self-face recognition in individuals with autism spectrum disorders [Texte imprimé et/ou numérique] / Tomoyo MORITA, Auteur ; Hirotaka KOSAKA, Auteur ; Daisuke N. SAITO, Auteur ; Takeshi FUJII, Auteur ; Makoto ISHITOBI, Auteur ; Toshio MUNESUE, Auteur ; Keisuke INOHARA, Auteur ; Hidehiko OKAZAWA, Auteur ; Ryusuke KAKIGI, Auteur ; Norihiro SADATO, Auteur . - p.16-32. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 26 (June 2016) . - p.16-32 Mots-clés : Anterior cingulate cortex  Anterior insula  Autism spectrum disorder (ASD)  Being observed  Embarrassment  Functional magnetic resonance imaging  Self-face Index. décimale : PER Périodiques Résumé : When exposed to self-face images, individuals often experience embarrassment, which is enhanced by being observed. This self-evaluative emotion is related to activity in the right anterior insula and the functional connectivity between the anterior cingulate and prefrontal cortices. Coupling between cognitive evaluation of self-face images and emotional response to them (cognitive–emotional coupling) is weaker in individuals with autism spectrum disorder (ASD), in parallel with reduced activity of the right insula. To determine whether self-evaluative emotions of individuals with ASD are less strongly impacted by observation, we conducted functional MRI in 14 adult men with ASD and 18 age-matched control men while the participants viewed self-face images. Increased embarrassment upon observation was positively correlated with increased activity in the right anterior insula in the control group, but not in the ASD group. In addition, awareness of being observed enhanced cognitive–emotional coupling in the controls but not in the ASD group. The coupling was correlated with the functional connectivity between the anterior cingulate and medial prefrontal cortices. These results suggest that the reduced impact of observation on embarrassment induced by self-face images in individuals with ASD is related to impairment in the right anterior insula, which is involved in creating subjective feelings, and the anterior cingulate cortex, which acts as a hub for integrating information from others during self-face evaluation. En ligne : http://dx.doi.org/10.1016/j.rasd.2016.02.011 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=285

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