Child dopamine active transporter 1 genotype and parenting: Evidence for evocative gene–environment correlations / Elizabeth P. HAYDEN in Development and Psychopathology, 25-1 (February 2013)  

Public ISBD [article]  inDevelopment and Psychopathology > 25-1 (February 2013) . - p.163-173 Titre : Child dopamine active transporter 1 genotype and parenting: Evidence for evocative gene–environment correlations Type de document : Texte imprimé et/ou numérique Auteurs : Elizabeth P. HAYDEN, Auteur ; Brigitte HANNA, Auteur ; Haroon I. SHEIKH, Auteur ; Rebecca S. LAPTOOK, Auteur ; Jiyon KIM, Auteur ; Shiva M. SINGH, Auteur ; Daniel N. KLEIN, Auteur Article en page(s) : p.163-173 Index. décimale : PER Périodiques Résumé : The dopamine active transporter 1 (DAT1) gene is implicated in psychopathology risk. Although the processes by which this gene exerts its effects on risk are poorly understood, a small body of research suggests that the DAT1 gene influences early emerging negative emotionality, a marker of children's psychopathology risk. As child negative emotionality evokes negative parenting practices, the DAT1 gene may also play a role in gene–environment correlations. To test this model, children (N = 365) were genotyped for the DAT1 gene and participated in standardized parent–child interaction tasks with their primary caregiver. The DAT1 gene 9-repeat variant was associated with child negative affect expressed toward the parent during parent–child interactions, and parents of children with a 9-repeat allele exhibited more hostility and lower guidance/engagement than parents of children without a 9-repeat allele. These gene–environment associations were partially mediated by child negative affect toward the parent. The findings implicate a specific polymorphism in eliciting negative parenting, suggesting that evocative associations play a role in elevating children's risk for emotional trajectories toward psychopathology risk. En ligne : http://dx.doi.org/10.1017/S0954579412000971 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=190 [article] Child dopamine active transporter 1 genotype and parenting: Evidence for evocative gene–environment correlations [Texte imprimé et/ou numérique] / Elizabeth P. HAYDEN, Auteur ; Brigitte HANNA, Auteur ; Haroon I. SHEIKH, Auteur ; Rebecca S. LAPTOOK, Auteur ; Jiyon KIM, Auteur ; Shiva M. SINGH, Auteur ; Daniel N. KLEIN, Auteur . - p.163-173. in Development and Psychopathology > 25-1 (February 2013) . - p.163-173 Index. décimale : PER Périodiques Résumé : The dopamine active transporter 1 (DAT1) gene is implicated in psychopathology risk. Although the processes by which this gene exerts its effects on risk are poorly understood, a small body of research suggests that the DAT1 gene influences early emerging negative emotionality, a marker of children's psychopathology risk. As child negative emotionality evokes negative parenting practices, the DAT1 gene may also play a role in gene–environment correlations. To test this model, children (N = 365) were genotyped for the DAT1 gene and participated in standardized parent–child interaction tasks with their primary caregiver. The DAT1 gene 9-repeat variant was associated with child negative affect expressed toward the parent during parent–child interactions, and parents of children with a 9-repeat allele exhibited more hostility and lower guidance/engagement than parents of children without a 9-repeat allele. These gene–environment associations were partially mediated by child negative affect toward the parent. The findings implicate a specific polymorphism in eliciting negative parenting, suggesting that evocative associations play a role in elevating children's risk for emotional trajectories toward psychopathology risk. En ligne : http://dx.doi.org/10.1017/S0954579412000971 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=190

Correlates of the CBCL-dysregulation profile in preschool-aged children / Jiyon KIM in Journal of Child Psychology and Psychiatry, 53-9 (September 2012)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 53-9 (September 2012) . - p.918-26 Titre : Correlates of the CBCL-dysregulation profile in preschool-aged children Type de document : Texte imprimé et/ou numérique Auteurs : Jiyon KIM, Auteur ; Gabrielle A. CARLSON, Auteur ; Stephanie E. MEYER, Auteur ; Sara J. BUFFERD, Auteur ; Lea R. DOUGHERTY, Auteur ; Margaret DYSON, Auteur ; Rebecca S. LAPTOOK, Auteur ; Thomas M. OLINO, Auteur ; Daniel N. KLEIN, Auteur Année de publication : 2012 Article en page(s) : p.918-26 Langues : Anglais (eng) Mots-clés : CBCL  dysregulation  preschool  children  comorbidity Index. décimale : PER Périodiques Résumé : Background:  A growing literature indicates that the Child Behavior Checklist-Dysregulation Profile (CBCL-DP) identifies youths with heightened risk for severe psychopathology, comorbidity, and impairment. However, this work has focused on school-age children and adolescents; no studies have examined whether preschool-aged children with the CBCL-DP exhibit a similar constellation of problems. Method:  Using a community sample of preschoolers, we compared children with (N = 61) and without (N = 488) the CBCL-DP on a broad range of variables assessed using multiple methods. Results:  Univariate analyses revealed numerous differences between children with the CBCL-DP and their peers on psychiatric symptomatology, temperament, parenting behavior, and parental personality, psychopathology, and marital functioning. In multivariate analyses, children with the CBCL-DP exhibited greater temperamental negative affectivity and lower effortful control. They also had more depressive and oppositional defiant symptoms, as well as greater functional impairment. Parents of CBCL-DP children reported engaging in more punitive, controlling parenting behavior than parents of non-profile children. Conclusions:  In a non-clinical sample of preschoolers, the CBCL-DP is associated with extensive emotional and behavioral dysregulation and maladaptive parenting. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2012.02546.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=179 [article] Correlates of the CBCL-dysregulation profile in preschool-aged children [Texte imprimé et/ou numérique] / Jiyon KIM, Auteur ; Gabrielle A. CARLSON, Auteur ; Stephanie E. MEYER, Auteur ; Sara J. BUFFERD, Auteur ; Lea R. DOUGHERTY, Auteur ; Margaret DYSON, Auteur ; Rebecca S. LAPTOOK, Auteur ; Thomas M. OLINO, Auteur ; Daniel N. KLEIN, Auteur . - 2012 . - p.918-26. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 53-9 (September 2012) . - p.918-26 Mots-clés : CBCL  dysregulation  preschool  children  comorbidity Index. décimale : PER Périodiques Résumé : Background:  A growing literature indicates that the Child Behavior Checklist-Dysregulation Profile (CBCL-DP) identifies youths with heightened risk for severe psychopathology, comorbidity, and impairment. However, this work has focused on school-age children and adolescents; no studies have examined whether preschool-aged children with the CBCL-DP exhibit a similar constellation of problems. Method:  Using a community sample of preschoolers, we compared children with (N = 61) and without (N = 488) the CBCL-DP on a broad range of variables assessed using multiple methods. Results:  Univariate analyses revealed numerous differences between children with the CBCL-DP and their peers on psychiatric symptomatology, temperament, parenting behavior, and parental personality, psychopathology, and marital functioning. In multivariate analyses, children with the CBCL-DP exhibited greater temperamental negative affectivity and lower effortful control. They also had more depressive and oppositional defiant symptoms, as well as greater functional impairment. Parents of CBCL-DP children reported engaging in more punitive, controlling parenting behavior than parents of non-profile children. Conclusions:  In a non-clinical sample of preschoolers, the CBCL-DP is associated with extensive emotional and behavioral dysregulation and maladaptive parenting. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2012.02546.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=179

Do positive and negative temperament traits interact in predicting risk for depression? A resting EEG study of 329 preschoolers / Stewart A. SHANKMAN in Development and Psychopathology, 23-2 (May 2011)  

Public ISBD [article]  inDevelopment and Psychopathology > 23-2 (May 2011) . - p.551-562 Titre : Do positive and negative temperament traits interact in predicting risk for depression? A resting EEG study of 329 preschoolers Type de document : Texte imprimé et/ou numérique Auteurs : Stewart A. SHANKMAN, Auteur ; Daniel N. KLEIN, Auteur ; Dana C. TORPEY, Auteur ; Thomas M. OLINO, Auteur ; Margaret DYSON, Auteur ; Jiyon KIM, Auteur ; C. Emily DURBIN, Auteur ; Brady D. NELSON, Auteur ; Craig E. TENKE, Auteur Année de publication : 2011 Article en page(s) : p.551-562 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Researchers have long been interested in whether particular temperamental traits in childhood connote risk for depressive disorders. For example, children characterized as having high negative emotionality (NE; sadness, fear, anger) and low positive emotionality (PE; anhedonia, listlessness, and lack of enthusiasm) are hypothesized to be at risk for depression. Few studies, however, have examined whether (and how) these two temperamental dimensions interact to confer risk. In a sample of 329 preschoolers, the present study addressed this question by examining the relation between PE and NE and asymmetry in resting EEG activity in frontal and posterior regions, which are putative biomarkers for depression. Using a laboratory battery to define temperament, we found an interaction of PE and NE on posterior asymmetry. Specifically, when PE was high, NE was associated with greater relative right activity. When PE was low, NE was not related to posterior asymmetry. These results were driven by differences in EEG activity in right posterior regions, an area associated with emotional processing and arousal, and were specific to girls. We found no relation between temperament and frontal asymmetry. These findings suggest that, at least for girls, PE and NE may have an interactive effect on risk for depression. En ligne : http://dx.doi.org/10.1017/S0954579411000022 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121 [article] Do positive and negative temperament traits interact in predicting risk for depression? A resting EEG study of 329 preschoolers [Texte imprimé et/ou numérique] / Stewart A. SHANKMAN, Auteur ; Daniel N. KLEIN, Auteur ; Dana C. TORPEY, Auteur ; Thomas M. OLINO, Auteur ; Margaret DYSON, Auteur ; Jiyon KIM, Auteur ; C. Emily DURBIN, Auteur ; Brady D. NELSON, Auteur ; Craig E. TENKE, Auteur . - 2011 . - p.551-562. Langues : Anglais (eng) in Development and Psychopathology > 23-2 (May 2011) . - p.551-562 Index. décimale : PER Périodiques Résumé : Researchers have long been interested in whether particular temperamental traits in childhood connote risk for depressive disorders. For example, children characterized as having high negative emotionality (NE; sadness, fear, anger) and low positive emotionality (PE; anhedonia, listlessness, and lack of enthusiasm) are hypothesized to be at risk for depression. Few studies, however, have examined whether (and how) these two temperamental dimensions interact to confer risk. In a sample of 329 preschoolers, the present study addressed this question by examining the relation between PE and NE and asymmetry in resting EEG activity in frontal and posterior regions, which are putative biomarkers for depression. Using a laboratory battery to define temperament, we found an interaction of PE and NE on posterior asymmetry. Specifically, when PE was high, NE was associated with greater relative right activity. When PE was low, NE was not related to posterior asymmetry. These results were driven by differences in EEG activity in right posterior regions, an area associated with emotional processing and arousal, and were specific to girls. We found no relation between temperament and frontal asymmetry. These findings suggest that, at least for girls, PE and NE may have an interactive effect on risk for depression. En ligne : http://dx.doi.org/10.1017/S0954579411000022 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121

Electrocortical reactivity to emotional faces in young children and associations with maternal and paternal depression / Autumn KUJAWA in Journal of Child Psychology and Psychiatry, 53-2 (February 2012)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 53-2 (February 2012) . - p.207-215 Titre : Electrocortical reactivity to emotional faces in young children and associations with maternal and paternal depression Type de document : Texte imprimé et/ou numérique Auteurs : Autumn KUJAWA, Auteur ; Greg HAJCAK, Auteur ; Dana C. TORPEY, Auteur ; Jiyon KIM, Auteur ; Daniel N. KLEIN, Auteur Année de publication : 2012 Article en page(s) : p.207-215 Langues : Anglais (eng) Mots-clés : Depression  vulnerability markers  emotion  psychophysiology Index. décimale : PER Périodiques Résumé : Background:  The late positive potential (LPP) is an event-related potential component that indexes selective attention toward motivationally salient information and is sensitive to emotional stimuli. Few studies have examined the LPP in children. Depression has been associated with reduced reactivity to negative and positive emotional stimuli, including reduced LPPs in response to emotional faces. The current study sought to identify the time course and scalp distribution of the LPP in response to emotional faces in young children and to determine whether reduced reactivity is observed among children at risk for depression. Methods:  Electrocortical reactivity to emotional faces was examined in a large sample of young children and as a function of maternal and paternal depression. Results:  In the overall sample, emotional faces were associated with increased positivities compared to neutral faces at occipital sites 200–600 ms after stimulus onset and at parietal sites 600–1,000 ms after stimulus onset. Children of mothers with a history of depressive disorders exhibited reduced differentiation in the early occipital LPP for emotional compared to neutral faces. Conclusions:  Results suggest that children as young as 6 years exhibit LPPs to emotional faces, and patterns of electrocortical reactivity to emotional stimuli may be associated with vulnerability to depressive disorders. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02461.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=150 [article] Electrocortical reactivity to emotional faces in young children and associations with maternal and paternal depression [Texte imprimé et/ou numérique] / Autumn KUJAWA, Auteur ; Greg HAJCAK, Auteur ; Dana C. TORPEY, Auteur ; Jiyon KIM, Auteur ; Daniel N. KLEIN, Auteur . - 2012 . - p.207-215. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 53-2 (February 2012) . - p.207-215 Mots-clés : Depression  vulnerability markers  emotion  psychophysiology Index. décimale : PER Périodiques Résumé : Background:  The late positive potential (LPP) is an event-related potential component that indexes selective attention toward motivationally salient information and is sensitive to emotional stimuli. Few studies have examined the LPP in children. Depression has been associated with reduced reactivity to negative and positive emotional stimuli, including reduced LPPs in response to emotional faces. The current study sought to identify the time course and scalp distribution of the LPP in response to emotional faces in young children and to determine whether reduced reactivity is observed among children at risk for depression. Methods:  Electrocortical reactivity to emotional faces was examined in a large sample of young children and as a function of maternal and paternal depression. Results:  In the overall sample, emotional faces were associated with increased positivities compared to neutral faces at occipital sites 200–600 ms after stimulus onset and at parietal sites 600–1,000 ms after stimulus onset. Children of mothers with a history of depressive disorders exhibited reduced differentiation in the early occipital LPP for emotional compared to neutral faces. Conclusions:  Results suggest that children as young as 6 years exhibit LPPs to emotional faces, and patterns of electrocortical reactivity to emotional stimuli may be associated with vulnerability to depressive disorders. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02461.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=150

Error-related brain activity in young children: associations with parental anxiety and child temperamental negative emotionality / Dana C. TORPEY in Journal of Child Psychology and Psychiatry, 54-8 (August 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-8 (August 2013) . - p.854-862 Titre : Error-related brain activity in young children: associations with parental anxiety and child temperamental negative emotionality Type de document : Texte imprimé et/ou numérique Auteurs : Dana C. TORPEY, Auteur ; Greg HAJCAK, Auteur ; Jiyon KIM, Auteur ; Autumn KUJAWA, Auteur ; Margaret DYSON, Auteur ; Thomas M. OLINO, Auteur ; Daniel N. KLEIN, Auteur Article en page(s) : p.854-862 Langues : Anglais (eng) Mots-clés : Anxiety  high risk studies  psychophysiology  temperament Index. décimale : PER Périodiques Résumé : Background: There is increasing interest in error-related brain activity in anxiety disorders. The error-related negativity (ERN) is a negative deflection in the event-related potential approximately 50 ms after errors compared to correct responses. Recent studies suggest that the ERN may be a biomarker for anxiety, as it is positively associated with anxiety disorders and traits in adults and older youth. However, it is not known if the ERN in young children is related to risk for anxiety disorders. We addressed this by examining the association of six-year olds' ERNs with two established risk factors for anxiety: parental anxiety disorder and child temperamental negative emotionality (NE). Method: The ERN was assessed using a Go/No-Go task in a community sample of 413 six-year olds. In a prior assessment at age 3, child temperament was evaluated using a laboratory observational measure and parental psychopathology was assessed using semi-structured diagnostic interviews. Results: Children of mothers with anxiety disorders and children with greater temperamental NE (particularly fearfulness) exhibited significantly smaller ERNs than their peers. Paternal psychopathology, maternal mood and substance use disorders, and child positive emotionality were not associated with children's ERNs. Conclusion: Both maternal anxiety disorders and child NE (particularly fearfulness) were significantly associated with children's ERNs. However, the direction of these associations was opposite to the relations between ERNs and anxiety in older youth and adults. These results suggest that there may be a difference between risk and disorder status in the relation of error-related brain activity to anxiety between early childhood and late childhood/ early adolescence. En ligne : http://dx.doi.org/10.1111/jcpp.12041 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=210 [article] Error-related brain activity in young children: associations with parental anxiety and child temperamental negative emotionality [Texte imprimé et/ou numérique] / Dana C. TORPEY, Auteur ; Greg HAJCAK, Auteur ; Jiyon KIM, Auteur ; Autumn KUJAWA, Auteur ; Margaret DYSON, Auteur ; Thomas M. OLINO, Auteur ; Daniel N. KLEIN, Auteur . - p.854-862. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-8 (August 2013) . - p.854-862 Mots-clés : Anxiety  high risk studies  psychophysiology  temperament Index. décimale : PER Périodiques Résumé : Background: There is increasing interest in error-related brain activity in anxiety disorders. The error-related negativity (ERN) is a negative deflection in the event-related potential approximately 50 ms after errors compared to correct responses. Recent studies suggest that the ERN may be a biomarker for anxiety, as it is positively associated with anxiety disorders and traits in adults and older youth. However, it is not known if the ERN in young children is related to risk for anxiety disorders. We addressed this by examining the association of six-year olds' ERNs with two established risk factors for anxiety: parental anxiety disorder and child temperamental negative emotionality (NE). Method: The ERN was assessed using a Go/No-Go task in a community sample of 413 six-year olds. In a prior assessment at age 3, child temperament was evaluated using a laboratory observational measure and parental psychopathology was assessed using semi-structured diagnostic interviews. Results: Children of mothers with anxiety disorders and children with greater temperamental NE (particularly fearfulness) exhibited significantly smaller ERNs than their peers. Paternal psychopathology, maternal mood and substance use disorders, and child positive emotionality were not associated with children's ERNs. Conclusion: Both maternal anxiety disorders and child NE (particularly fearfulness) were significantly associated with children's ERNs. However, the direction of these associations was opposite to the relations between ERNs and anxiety in older youth and adults. These results suggest that there may be a difference between risk and disorder status in the relation of error-related brain activity to anxiety between early childhood and late childhood/ early adolescence. En ligne : http://dx.doi.org/10.1111/jcpp.12041 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=210

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