Associations among depression, perceived self-efficacy, and immune function and health in preadolescent children / Mary T. CASERTA in Development and Psychopathology, 23-4 (November 2011)  

Public ISBD [article]  inDevelopment and Psychopathology > 23-4 (November 2011) . - p.1139-1147 Titre : Associations among depression, perceived self-efficacy, and immune function and health in preadolescent children Type de document : Texte imprimé et/ou numérique Auteurs : Mary T. CASERTA, Auteur ; Peter A. WYMAN, Auteur ; Hongyue WANG, Auteur ; Jan MOYNIHAN, Auteur ; Thomas G. O'CONNOR, Auteur Année de publication : 2011 Article en page(s) : p.1139-1147 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Experimental animal studies and adult research consistently show that stress exposure and/or psychological symptoms are associated with poorer health and immune functioning. The application to children is not yet clear, however, and we lack developmental models for studies in this area. The objective of this paper was to test the hypothesis that self-reported self-efficacy and depression, two markers of psychological well-being in children, would predict immunity and rate of illnesses. The data are based on a prospective study of 141 healthy, normally developing children aged 7–13 years who were recruited from an ambulatory pediatric setting. Children completed self-efficacy and depression measures and had blood obtained for IL-6 plasma levels and natural killer cell functional assays on three occasions, 6 months apart. Parents maintained weekly child illness diaries over 1 year using a thermometer to record fever. Parent psychiatric symptoms and income were used as covariates. Results indicated that, across the three occasions of measurement collected over the 1-year period, higher perceived self-efficacy was significantly associated with lower plasma interleukin 6 concentrations. There was no overall main effect of depressive symptoms on immune measures; however, for older girls, higher depression was associated with elevated natural killer cell cytotoxicity and an increased rate of total illnesses and febrile illnesses. The findings provide some of the first evidence that psychological processes are associated with immunity and health in a normally developing sample of preadolescents. Furthermore, the pattern of results suggests a modified model of a link between psychological well-being and immunological processes in children. These results build on and expand research on the notion of allostatic load and develop a groundwork for developmental studies in this area. En ligne : http://dx.doi.org/10.1017/S0954579411000526 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=146 [article] Associations among depression, perceived self-efficacy, and immune function and health in preadolescent children [Texte imprimé et/ou numérique] / Mary T. CASERTA, Auteur ; Peter A. WYMAN, Auteur ; Hongyue WANG, Auteur ; Jan MOYNIHAN, Auteur ; Thomas G. O'CONNOR, Auteur . - 2011 . - p.1139-1147. Langues : Anglais (eng) in Development and Psychopathology > 23-4 (November 2011) . - p.1139-1147 Index. décimale : PER Périodiques Résumé : Experimental animal studies and adult research consistently show that stress exposure and/or psychological symptoms are associated with poorer health and immune functioning. The application to children is not yet clear, however, and we lack developmental models for studies in this area. The objective of this paper was to test the hypothesis that self-reported self-efficacy and depression, two markers of psychological well-being in children, would predict immunity and rate of illnesses. The data are based on a prospective study of 141 healthy, normally developing children aged 7–13 years who were recruited from an ambulatory pediatric setting. Children completed self-efficacy and depression measures and had blood obtained for IL-6 plasma levels and natural killer cell functional assays on three occasions, 6 months apart. Parents maintained weekly child illness diaries over 1 year using a thermometer to record fever. Parent psychiatric symptoms and income were used as covariates. Results indicated that, across the three occasions of measurement collected over the 1-year period, higher perceived self-efficacy was significantly associated with lower plasma interleukin 6 concentrations. There was no overall main effect of depressive symptoms on immune measures; however, for older girls, higher depression was associated with elevated natural killer cell cytotoxicity and an increased rate of total illnesses and febrile illnesses. The findings provide some of the first evidence that psychological processes are associated with immunity and health in a normally developing sample of preadolescents. Furthermore, the pattern of results suggests a modified model of a link between psychological well-being and immunological processes in children. These results build on and expand research on the notion of allostatic load and develop a groundwork for developmental studies in this area. En ligne : http://dx.doi.org/10.1017/S0954579411000526 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=146

Comparative effectiveness trial: Modular behavior approach for young autistic children compared to comprehensive behavioral intervention / Cynthia ANDERSON in Autism Research, 17-11 (November 2024)  

Public ISBD [article]  inAutism Research > 17-11 (November 2024) . - p.2430-2446 Titre : Comparative effectiveness trial: Modular behavior approach for young autistic children compared to comprehensive behavioral intervention Type de document : Texte imprimé et/ou numérique Auteurs : Cynthia ANDERSON, Auteur ; Samantha HOCHHEIMER, Auteur ; Zachary WARREN, Auteur ; Eric BUTTER, Auteur ; Susan L. HYMAN, Auteur ; Hongyue WANG, Auteur ; Lisa WALLACE, Auteur ; Lynne LEVATO, Auteur ; Ryan MARTIN, Auteur ; Kevin G. STEPHENSON, Auteur ; Megan NORRIS, Auteur ; Wynn JACQUELINE, Auteur ; Tristram SMITH, Auteur ; Cynthia R. JOHNSON, Auteur Article en page(s) : p.2430-2446 Langues : Anglais (eng) Mots-clés : applied behavior analysis  autism  behavioral intervention  comprehensive behavior intervention (CBI)  discrete trial training (DTT)  early intensive Behavioral intervention (EIBI)  naturalistic developmental Behavioral interventions (NDBIs)  noninferiority design  randomized clinical trial (RCT) Index. décimale : PER Périodiques Résumé : Abstract This 24-week single-blind trial tested a modular approach for young autistic children (MAYAC) that was delivered for fewer hours per week and modified based on child progress and parental input compared to comprehensive behavioral intervention treatment as usual (CBI, TAU). Participants were autistic children, ages 18?60?months of age. MAYAC was initially 5?h of intervention per week, one of which was parent training and the other four direct therapy focusing on social communication and engagement, but additional modules could be added for up to 10?h per week. Comprehensive behavior intervention was delivered for ?15?h per week. Outcome measures included the Vineland Adaptive Behavior Scales; VABS, the Ohio Autism Clinical Improvement Scale ? Autism Severity; OACIS ? AS and the Pervasive Developmental Disorder Behavior Inventory ? Parent; PDDBI-P. Implementation and parent satisfaction measures were also collected. Fifty-six children, mean age of 34?months, were randomized. Within-group analysis revealed significant improvements from baseline to week 24 for both MAYAC (p?95%) as was parent satisfaction. Findings from this small trial are promising and suggest MAYAC may be an alternative for some young autistic children and their families to CBI, TAU. En ligne : https://doi.org/10.1002/aur.3240 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542 [article] Comparative effectiveness trial: Modular behavior approach for young autistic children compared to comprehensive behavioral intervention [Texte imprimé et/ou numérique] / Cynthia ANDERSON, Auteur ; Samantha HOCHHEIMER, Auteur ; Zachary WARREN, Auteur ; Eric BUTTER, Auteur ; Susan L. HYMAN, Auteur ; Hongyue WANG, Auteur ; Lisa WALLACE, Auteur ; Lynne LEVATO, Auteur ; Ryan MARTIN, Auteur ; Kevin G. STEPHENSON, Auteur ; Megan NORRIS, Auteur ; Wynn JACQUELINE, Auteur ; Tristram SMITH, Auteur ; Cynthia R. JOHNSON, Auteur . - p.2430-2446. Langues : Anglais (eng) in Autism Research > 17-11 (November 2024) . - p.2430-2446 Mots-clés : applied behavior analysis  autism  behavioral intervention  comprehensive behavior intervention (CBI)  discrete trial training (DTT)  early intensive Behavioral intervention (EIBI)  naturalistic developmental Behavioral interventions (NDBIs)  noninferiority design  randomized clinical trial (RCT) Index. décimale : PER Périodiques Résumé : Abstract This 24-week single-blind trial tested a modular approach for young autistic children (MAYAC) that was delivered for fewer hours per week and modified based on child progress and parental input compared to comprehensive behavioral intervention treatment as usual (CBI, TAU). Participants were autistic children, ages 18?60?months of age. MAYAC was initially 5?h of intervention per week, one of which was parent training and the other four direct therapy focusing on social communication and engagement, but additional modules could be added for up to 10?h per week. Comprehensive behavior intervention was delivered for ?15?h per week. Outcome measures included the Vineland Adaptive Behavior Scales; VABS, the Ohio Autism Clinical Improvement Scale ? Autism Severity; OACIS ? AS and the Pervasive Developmental Disorder Behavior Inventory ? Parent; PDDBI-P. Implementation and parent satisfaction measures were also collected. Fifty-six children, mean age of 34?months, were randomized. Within-group analysis revealed significant improvements from baseline to week 24 for both MAYAC (p?95%) as was parent satisfaction. Findings from this small trial are promising and suggest MAYAC may be an alternative for some young autistic children and their families to CBI, TAU. En ligne : https://doi.org/10.1002/aur.3240 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542

Is Neonatal Jaundice Associated with Autism Spectrum Disorders: A Systematic Review / Sanjiv B. AMIN in Journal of Autism and Developmental Disorders, 41-11 (November 2011)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 41-11 (November 2011) . - p.1455-1463 Titre : Is Neonatal Jaundice Associated with Autism Spectrum Disorders: A Systematic Review Type de document : Texte imprimé et/ou numérique Auteurs : Sanjiv B. AMIN, Auteur ; Tristram SMITH, Auteur ; Hongyue WANG, Auteur Année de publication : 2011 Article en page(s) : p.1455-1463 Langues : Anglais (eng) Mots-clés : Unconjugated hyperbilirubinemia  Free bilirubin  Premature infants  Meta-analysis Index. décimale : PER Périodiques Résumé : Using guidelines of the Meta-analysis of Observational Studies in Epidemiology Group, we systematically reviewed the literature on neonatal jaundice (unconjugated hyperbilirubinemia) and Autism Spectrum Disorder (ASD) in term and preterm infants. Thirteen studies were included in a meta-analysis. Most used retrospective matched case–control designs. There was significant heterogeneity (Q = 31, p = 0.002) and no evidence of publication bias (p = 0.12). Overall, jaundice, assessed by total serum bilirubin (TSB), was associated with ASD (OR, 1.43, 95% CI 1.22–1.67, random effect model). This association was not found in preterms (OR 0.7, 95% CI 0.38–1.02) but deserves further investigation since other measures of bilirubin such as unbound unconjugated bilirubin may be better predictors of neurotoxicity than TSB in preterms. En ligne : http://dx.doi.org/10.1007/s10803-010-1169-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=147 [article] Is Neonatal Jaundice Associated with Autism Spectrum Disorders: A Systematic Review [Texte imprimé et/ou numérique] / Sanjiv B. AMIN, Auteur ; Tristram SMITH, Auteur ; Hongyue WANG, Auteur . - 2011 . - p.1455-1463. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 41-11 (November 2011) . - p.1455-1463 Mots-clés : Unconjugated hyperbilirubinemia  Free bilirubin  Premature infants  Meta-analysis Index. décimale : PER Périodiques Résumé : Using guidelines of the Meta-analysis of Observational Studies in Epidemiology Group, we systematically reviewed the literature on neonatal jaundice (unconjugated hyperbilirubinemia) and Autism Spectrum Disorder (ASD) in term and preterm infants. Thirteen studies were included in a meta-analysis. Most used retrospective matched case–control designs. There was significant heterogeneity (Q = 31, p = 0.002) and no evidence of publication bias (p = 0.12). Overall, jaundice, assessed by total serum bilirubin (TSB), was associated with ASD (OR, 1.43, 95% CI 1.22–1.67, random effect model). This association was not found in preterms (OR 0.7, 95% CI 0.38–1.02) but deserves further investigation since other measures of bilirubin such as unbound unconjugated bilirubin may be better predictors of neurotoxicity than TSB in preterms. En ligne : http://dx.doi.org/10.1007/s10803-010-1169-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=147

Parent Outcomes from a Randomized Controlled Trial Investigating a Modular Behavioral Intervention for Young Autistic Children / Lynne LEVATO in Autism Research, 18-3 (March 2025)  

Public ISBD [article]  inAutism Research > 18-3 (March 2025) . - p.675-683 Titre : Parent Outcomes from a Randomized Controlled Trial Investigating a Modular Behavioral Intervention for Young Autistic Children Type de document : Texte imprimé et/ou numérique Auteurs : Lynne LEVATO, Auteur ; Samantha HOCHHEIMER, Auteur ; Hongyue WANG, Auteur ; Lisa WALLACE, Auteur ; Susan HYMAN, Auteur ; Cynthia ANDERSON, Auteur ; Zachary WARREN, Auteur ; Eric BUTTER, Auteur ; Ryan MARTIN, Auteur ; Evon LEE, Auteur ; Tristram SMITH, Auteur ; Cynthia JOHNSON, Auteur Article en page(s) : p.675-683 Langues : Anglais (eng) Mots-clés : applied behavior analysis  autism  behavioral intervention  parent training  parental competence  parental stress  randomized clinical trial (RCT) Index. décimale : PER Périodiques Résumé : ABSTRACT We assessed parent stress and competence outcomes from participation in a randomized controlled trial of a modular behavioral intervention (Modular Approach for Young Autistic Children; MAYAC) compared to a treatment-as-usual comprehensive behavioral intervention (CBI). Throughout their participation, parents of military families were included in their child's treatment (e.g., identifying goals, learning strategies to support their child) and reported on their feelings of stress using the Parenting Stress Index?4, Short Form (PSI-4), as well as their feelings of satisfaction and efficacy as a parent on the Parenting Sense of Competence (PSOC) scale. A linear mixed model evaluated the differences in stress and competence from baseline to each assessment period through follow-up. There were no significant differences between groups in stress or competence ratings; however, there were within-group changes in both treatment arms over the course of the trial. In both groups, parent stress decreased, and competence increased over time, continuing to suggest that behavioral analytic intervention for young children with autism can promote positive parent outcomes. Trial Registration: ClinicalTrial.gov identifier: NCT04078061 En ligne : https://doi.org/10.1002/aur.70013 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=550 [article] Parent Outcomes from a Randomized Controlled Trial Investigating a Modular Behavioral Intervention for Young Autistic Children [Texte imprimé et/ou numérique] / Lynne LEVATO, Auteur ; Samantha HOCHHEIMER, Auteur ; Hongyue WANG, Auteur ; Lisa WALLACE, Auteur ; Susan HYMAN, Auteur ; Cynthia ANDERSON, Auteur ; Zachary WARREN, Auteur ; Eric BUTTER, Auteur ; Ryan MARTIN, Auteur ; Evon LEE, Auteur ; Tristram SMITH, Auteur ; Cynthia JOHNSON, Auteur . - p.675-683. Langues : Anglais (eng) in Autism Research > 18-3 (March 2025) . - p.675-683 Mots-clés : applied behavior analysis  autism  behavioral intervention  parent training  parental competence  parental stress  randomized clinical trial (RCT) Index. décimale : PER Périodiques Résumé : ABSTRACT We assessed parent stress and competence outcomes from participation in a randomized controlled trial of a modular behavioral intervention (Modular Approach for Young Autistic Children; MAYAC) compared to a treatment-as-usual comprehensive behavioral intervention (CBI). Throughout their participation, parents of military families were included in their child's treatment (e.g., identifying goals, learning strategies to support their child) and reported on their feelings of stress using the Parenting Stress Index?4, Short Form (PSI-4), as well as their feelings of satisfaction and efficacy as a parent on the Parenting Sense of Competence (PSOC) scale. A linear mixed model evaluated the differences in stress and competence from baseline to each assessment period through follow-up. There were no significant differences between groups in stress or competence ratings; however, there were within-group changes in both treatment arms over the course of the trial. In both groups, parent stress decreased, and competence increased over time, continuing to suggest that behavioral analytic intervention for young children with autism can promote positive parent outcomes. Trial Registration: ClinicalTrial.gov identifier: NCT04078061 En ligne : https://doi.org/10.1002/aur.70013 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=550

The Gluten-Free/Casein-Free Diet: A Double-Blind Challenge Trial in Children with Autism / Susan L. HYMAN in Journal of Autism and Developmental Disorders, 46-1 (January 2016)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.205-220 Titre : The Gluten-Free/Casein-Free Diet: A Double-Blind Challenge Trial in Children with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Susan L. HYMAN, Auteur ; Patricia A. STEWART, Auteur ; Jennifer FOLEY, Auteur ; Usa CAIN, Auteur ; Robin PECK, Auteur ; Danielle D. MORRIS, Auteur ; Hongyue WANG, Auteur ; Tristram SMITH, Auteur Année de publication : 2016 Article en page(s) : p.205-220 Langues : Anglais (eng) Mots-clés : Autism  Diet therapy  Gluten-free  Casein-free  Treatment outcomes Index. décimale : PER Périodiques Résumé : To obtain information on the safety and efficacy of the gluten-free/casein-free (GFCF) diet, we placed 14 children with autism, age 3–5 years, on the diet for 4–6 weeks and then conducted a double-blind, placebo-controlled challenge study for 12 weeks while continuing the diet, with a 12-week follow-up. Dietary challenges were delivered via weekly snacks that contained gluten, casein, gluten and casein, or placebo. With nutritional counseling, the diet was safe and well-tolerated. However, dietary challenges did not have statistically significant effects on measures of physiologic functioning, behavior problems, or autism symptoms. Although these findings must be interpreted with caution because of the small sample size, the study does not provide evidence to support general use of the GFCF diet. En ligne : http://dx.doi.org/10.1007/s10803-015-2564-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278 [article] The Gluten-Free/Casein-Free Diet: A Double-Blind Challenge Trial in Children with Autism [Texte imprimé et/ou numérique] / Susan L. HYMAN, Auteur ; Patricia A. STEWART, Auteur ; Jennifer FOLEY, Auteur ; Usa CAIN, Auteur ; Robin PECK, Auteur ; Danielle D. MORRIS, Auteur ; Hongyue WANG, Auteur ; Tristram SMITH, Auteur . - 2016 . - p.205-220. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.205-220 Mots-clés : Autism  Diet therapy  Gluten-free  Casein-free  Treatment outcomes Index. décimale : PER Périodiques Résumé : To obtain information on the safety and efficacy of the gluten-free/casein-free (GFCF) diet, we placed 14 children with autism, age 3–5 years, on the diet for 4–6 weeks and then conducted a double-blind, placebo-controlled challenge study for 12 weeks while continuing the diet, with a 12-week follow-up. Dietary challenges were delivered via weekly snacks that contained gluten, casein, gluten and casein, or placebo. With nutritional counseling, the diet was safe and well-tolerated. However, dietary challenges did not have statistically significant effects on measures of physiologic functioning, behavior problems, or autism symptoms. Although these findings must be interpreted with caution because of the small sample size, the study does not provide evidence to support general use of the GFCF diet. En ligne : http://dx.doi.org/10.1007/s10803-015-2564-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278

Thinking Small to Think Big: Modular Approach for Autism Programming in Schools (MAAPS) / Cynthia M ANDERSON in Journal of Autism and Developmental Disorders, 51-1 (January 2021)  

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