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[n° ou bulletin] 17-11 - November 2024 [Texte imprimé et/ou numérique] . - 2024. Langues : Anglais (eng)
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Dépouillements
Ajouter le résultat dans votre panierExpanding perspectives on figurative language processing in autism spectrum disorder: A commentary on Lampri et al.'s review / Yun TIEN in Autism Research, 17-11 (November 2024)
Titre : Expanding perspectives on figurative language processing in autism spectrum disorder: A commentary on Lampri et al.'s review Type de document : Texte imprimé et/ou numérique Auteurs : Yun TIEN, Auteur ; Lien-Chung WEI, Auteur Article en page(s) : p.2194-2195 Langues : Anglais (eng) Mots-clés : autism spectrum disorder comprehension developmental trajectory figurative language language-specific factors production theory of mind Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.3249 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2194-2195[article] Expanding perspectives on figurative language processing in autism spectrum disorder: A commentary on Lampri et al.'s review [Texte imprimé et/ou numérique] / Yun TIEN, Auteur ; Lien-Chung WEI, Auteur . - p.2194-2195.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2194-2195
Mots-clés : autism spectrum disorder comprehension developmental trajectory figurative language language-specific factors production theory of mind Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.3249 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : Resilience and strengths in the Black autism community in the United States: A scoping review Type de document : Texte imprimé et/ou numérique Auteurs : Amber M. DAVIS, Auteur ; Nicole A. TELFER, Auteur ; Jonet ARTIS, Auteur ; Oluwatobi ABUBAKARE, Auteur ; Yolanda D. KELLER-BELL, Auteur ; Carmen CARUTHERS, Auteur ; Desiree R. JONES, Auteur ; Nigel P. PIERCE, Auteur Article en page(s) : p.2198-2222 Langues : Anglais (eng) Mots-clés : Black autism community Resiliency strengths Index. décimale : PER Périodiques Résumé : Abstract Gaps in research knowledge pertaining to resiliency factors and strengths among the Black autism community, inclusive of autistic persons and their support system exist. A scoping review was conducted to further explore quantitative, qualitative, and mixed methods studies that investigate resiliency factors and related strengths in the Black autism community in the United States. A total of 436 articles were identified, with 28 studies included in the final review. Results demonstrated that (1) strengths of Black autistic persons across the life course have been disregarded in research; (2) Black caregiver advocacy, while common, is also a developmental process that can be supported by community-based interventions; (3) informal supports including family and friends play an instrumental role in supporting the well-under investigated being of Black parents of autistic children; and (4) spirituality is often endorsed by Black caregivers of autistic children, such as playing a role in acceptance of the autism diagnosis and with coping with difficult life situations. Research and practice implications are discussed. En ligne : https://doi.org/10.1002/aur.3243 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2198-2222[article] Resilience and strengths in the Black autism community in the United States: A scoping review [Texte imprimé et/ou numérique] / Amber M. DAVIS, Auteur ; Nicole A. TELFER, Auteur ; Jonet ARTIS, Auteur ; Oluwatobi ABUBAKARE, Auteur ; Yolanda D. KELLER-BELL, Auteur ; Carmen CARUTHERS, Auteur ; Desiree R. JONES, Auteur ; Nigel P. PIERCE, Auteur . - p.2198-2222.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2198-2222
Mots-clés : Black autism community Resiliency strengths Index. décimale : PER Périodiques Résumé : Abstract Gaps in research knowledge pertaining to resiliency factors and strengths among the Black autism community, inclusive of autistic persons and their support system exist. A scoping review was conducted to further explore quantitative, qualitative, and mixed methods studies that investigate resiliency factors and related strengths in the Black autism community in the United States. A total of 436 articles were identified, with 28 studies included in the final review. Results demonstrated that (1) strengths of Black autistic persons across the life course have been disregarded in research; (2) Black caregiver advocacy, while common, is also a developmental process that can be supported by community-based interventions; (3) informal supports including family and friends play an instrumental role in supporting the well-under investigated being of Black parents of autistic children; and (4) spirituality is often endorsed by Black caregivers of autistic children, such as playing a role in acceptance of the autism diagnosis and with coping with difficult life situations. Research and practice implications are discussed. En ligne : https://doi.org/10.1002/aur.3243 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : Parental age at birth, telomere length, and autism spectrum disorders in the UK Biobank cohort Type de document : Texte imprimé et/ou numérique Auteurs : Qiaofeng YE, Auteur ; Abner T. APSLEY, Auteur ; Waylon J. HASTINGS, Auteur ; Laura ETZEL, Auteur ; Craig NEWSCHAFFER, Auteur ; Idan SHALEV, Auteur Article en page(s) : p.2223-2231 Langues : Anglais (eng) Mots-clés : adults autism spectrum disorders parental age at birth telomere length UK Biobank Index. décimale : PER Périodiques Résumé : Abstract Older parental age at birth is associated with increased risk of autism spectrum disorders (ASD) in offspring. Independently, shorter telomere length (TL) has also been shown to be associated with ASD in children. However, older paternal age at birth, with or without controlling for maternal age, has been associated with longer TL, a seemingly contradictory finding. Here, we conducted a retrospective cohort study among participants in the UK Biobank to disentangle associations between leukocyte TL and ASD status in adults, and the potential moderation by parental age on adult offspring's TL. Participants with ASD diagnosis (N?=?87) with a mean age of 46.0 (SD 4.4) years were matched to participants without ASD diagnosis (N?=?870) based on age, sex, ethnicity, education, household income, and assessment center. No statistically significant differences were seen in TL between participants with and without ASD when parental age at birth was not considered. However, there was a significant interaction between ASD diagnostic status and parental age on participants' TL, such that older paternal or maternal age at birth was more strongly associated with longer TL in participants with ASD. This study suggests that the shortened TL observed in children with ASD in previous research may partially depend on parental age at birth. Future studies tracking TL attrition before ASD diagnosis are warranted to depict temporal associations and the interacting effects of parental age at birth and ASD status on TL across the lifespan. En ligne : https://doi.org/10.1002/aur.3258 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2223-2231[article] Parental age at birth, telomere length, and autism spectrum disorders in the UK Biobank cohort [Texte imprimé et/ou numérique] / Qiaofeng YE, Auteur ; Abner T. APSLEY, Auteur ; Waylon J. HASTINGS, Auteur ; Laura ETZEL, Auteur ; Craig NEWSCHAFFER, Auteur ; Idan SHALEV, Auteur . - p.2223-2231.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2223-2231
Mots-clés : adults autism spectrum disorders parental age at birth telomere length UK Biobank Index. décimale : PER Périodiques Résumé : Abstract Older parental age at birth is associated with increased risk of autism spectrum disorders (ASD) in offspring. Independently, shorter telomere length (TL) has also been shown to be associated with ASD in children. However, older paternal age at birth, with or without controlling for maternal age, has been associated with longer TL, a seemingly contradictory finding. Here, we conducted a retrospective cohort study among participants in the UK Biobank to disentangle associations between leukocyte TL and ASD status in adults, and the potential moderation by parental age on adult offspring's TL. Participants with ASD diagnosis (N?=?87) with a mean age of 46.0 (SD 4.4) years were matched to participants without ASD diagnosis (N?=?870) based on age, sex, ethnicity, education, household income, and assessment center. No statistically significant differences were seen in TL between participants with and without ASD when parental age at birth was not considered. However, there was a significant interaction between ASD diagnostic status and parental age on participants' TL, such that older paternal or maternal age at birth was more strongly associated with longer TL in participants with ASD. This study suggests that the shortened TL observed in children with ASD in previous research may partially depend on parental age at birth. Future studies tracking TL attrition before ASD diagnosis are warranted to depict temporal associations and the interacting effects of parental age at birth and ASD status on TL across the lifespan. En ligne : https://doi.org/10.1002/aur.3258 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : Fast updating of stimulus history reveals weak internal representations of faces in autism Type de document : Texte imprimé et/ou numérique Auteurs : Marissa HARTSTON, Auteur ; Tal LULAV-BASH, Auteur ; Yael GOLDSTEIN-MARCUSOHN, Auteur ; Galia AVIDAN, Auteur ; Bat-Sheva HADAD, Auteur Article en page(s) : p.2232-2243 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder serial dependance Bayesian perception contextual effects face processing other-race effects regression to the mean Index. décimale : PER Périodiques Résumé : Abstract Atypical perception has been widely reported in autism spectrum disorders, and deficits in face recognition, specifically, are argued to be closely associated with social impairment experienced by these individuals. However, it is still debated (a) whether deficits are perceptually based, and (b) what the role is of experience-based refinements of perceptual face representations in autism. We investigated the effect of short- and long-term experienced stimulus history on face processing. Autistic and non-autistic individuals performed same-different judgments in a serial discrimination task where two consecutive faces were drawn from a distribution of morphed faces. Use of stimulus statistics was measured by testing the gravitation of face representations towards, the mean of a range of morphed faces around which they were sampled (regression-to-the-mean). The results show that unlike non-autistic individuals, representations of own- and other-race faces were equally biased by stimulus statistics in autistic individuals. Moreover, autistic individuals used the most recently exposed faces without forming a strong internal representation based on the overall experienced faces, indicating a weaker internal model of the ?typical? averaged face. This accumulated history of faces may underlie typical face specialization, and thus may account for the reduced specialization for own-race faces shown in autism. The results shed light on the way autistic people process and recognize faces, and on the basic mechanisms underlying atypical face perception. En ligne : https://doi.org/10.1002/aur.3236 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2232-2243[article] Fast updating of stimulus history reveals weak internal representations of faces in autism [Texte imprimé et/ou numérique] / Marissa HARTSTON, Auteur ; Tal LULAV-BASH, Auteur ; Yael GOLDSTEIN-MARCUSOHN, Auteur ; Galia AVIDAN, Auteur ; Bat-Sheva HADAD, Auteur . - p.2232-2243.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2232-2243
Mots-clés : Autism Spectrum Disorder serial dependance Bayesian perception contextual effects face processing other-race effects regression to the mean Index. décimale : PER Périodiques Résumé : Abstract Atypical perception has been widely reported in autism spectrum disorders, and deficits in face recognition, specifically, are argued to be closely associated with social impairment experienced by these individuals. However, it is still debated (a) whether deficits are perceptually based, and (b) what the role is of experience-based refinements of perceptual face representations in autism. We investigated the effect of short- and long-term experienced stimulus history on face processing. Autistic and non-autistic individuals performed same-different judgments in a serial discrimination task where two consecutive faces were drawn from a distribution of morphed faces. Use of stimulus statistics was measured by testing the gravitation of face representations towards, the mean of a range of morphed faces around which they were sampled (regression-to-the-mean). The results show that unlike non-autistic individuals, representations of own- and other-race faces were equally biased by stimulus statistics in autistic individuals. Moreover, autistic individuals used the most recently exposed faces without forming a strong internal representation based on the overall experienced faces, indicating a weaker internal model of the ?typical? averaged face. This accumulated history of faces may underlie typical face specialization, and thus may account for the reduced specialization for own-race faces shown in autism. The results shed light on the way autistic people process and recognize faces, and on the basic mechanisms underlying atypical face perception. En ligne : https://doi.org/10.1002/aur.3236 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : Eye-tracking training improves visuospatial working memory of children with attention-deficit/hyperactivity disorder and autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Agnes S. CHAN, Auteur ; Pui-Ying LEUNG, Auteur ; Tiffany Wing-Yin PANG, Auteur ; Sophia L. SZE, Auteur Article en page(s) : p.2244-2260 Langues : Anglais (eng) Mots-clés : ADHD ASD cognitive training eye-tracking flexibility visuospatial working memory Index. décimale : PER Périodiques Résumé : Abstract Given the close connection between eye movement and frontal lobe functions and some evidence supporting the effect of eye-tracking training on enhancing cognitive performance mediated by the frontal lobe, this study aimed to explore if after-school eye-tracking training can improve the visuospatial working memory (VSWM) and cognitive flexibility performance in children with attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). This study is a non-randomized cluster trial. Forty children from eight primary schools were selected, half receiving eye-tracking training for 20 sessions over 9?months, while the other half served as a waitlist control. They were matched on demographic characteristics and baseline cognitive performance. Their VSWM and cognitive flexibility were assessed at the beginning and end of the study. Results showed that children who received eye-tracking training, but not those on a waitlist, exhibited significant improvements in the total score and working memory span of the VSWM tests, and the correct responses in cognitive flexibility tests. Specifically, VSWM performance at higher span levels (5 or above) yielded a greater improvement. The findings suggest that eye-tracking training can be a feasible and effective after-school program for improving working memory and cognitive flexibility performance in children with ADHD and ASD. This study was prospectively registered at ClinicalTrials.gov (https://clinicaltrials.gov/, trial number: NCT05428657). En ligne : https://doi.org/10.1002/aur.3238 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2244-2260[article] Eye-tracking training improves visuospatial working memory of children with attention-deficit/hyperactivity disorder and autism spectrum disorder [Texte imprimé et/ou numérique] / Agnes S. CHAN, Auteur ; Pui-Ying LEUNG, Auteur ; Tiffany Wing-Yin PANG, Auteur ; Sophia L. SZE, Auteur . - p.2244-2260.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2244-2260
Mots-clés : ADHD ASD cognitive training eye-tracking flexibility visuospatial working memory Index. décimale : PER Périodiques Résumé : Abstract Given the close connection between eye movement and frontal lobe functions and some evidence supporting the effect of eye-tracking training on enhancing cognitive performance mediated by the frontal lobe, this study aimed to explore if after-school eye-tracking training can improve the visuospatial working memory (VSWM) and cognitive flexibility performance in children with attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). This study is a non-randomized cluster trial. Forty children from eight primary schools were selected, half receiving eye-tracking training for 20 sessions over 9?months, while the other half served as a waitlist control. They were matched on demographic characteristics and baseline cognitive performance. Their VSWM and cognitive flexibility were assessed at the beginning and end of the study. Results showed that children who received eye-tracking training, but not those on a waitlist, exhibited significant improvements in the total score and working memory span of the VSWM tests, and the correct responses in cognitive flexibility tests. Specifically, VSWM performance at higher span levels (5 or above) yielded a greater improvement. The findings suggest that eye-tracking training can be a feasible and effective after-school program for improving working memory and cognitive flexibility performance in children with ADHD and ASD. This study was prospectively registered at ClinicalTrials.gov (https://clinicaltrials.gov/, trial number: NCT05428657). En ligne : https://doi.org/10.1002/aur.3238 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : Autism is associated with in vivo changes in gray matter neurite architecture Type de document : Texte imprimé et/ou numérique Auteurs : Zachary P. CHRISTENSEN, Auteur ; Edward G. FREEDMAN, Auteur ; John J. FOXE, Auteur Article en page(s) : p.2261-2277 Langues : Anglais (eng) Mots-clés : autism cerebellum children and adolescents cytoarchitecture DWI gray matter neurodevelopment Index. décimale : PER Périodiques Résumé : Abstract Postmortem investigations in autism have identified anomalies in neural cytoarchitecture across limbic, cerebellar, and neocortical networks. These anomalies include narrow cell mini-columns and variable neuron density. However, difficulty obtaining sufficient post-mortem samples has often prevented investigations from converging on reproducible measures. Recent advances in processing magnetic resonance diffusion weighted images (DWI) make in vivo characterization of neuronal cytoarchitecture a potential alternative to post-mortem studies. Using extensive DWI data from the Adolescent Brain Cognitive Developmentsm (ABCD?) study 142 individuals with an autism diagnosis were compared with 8971 controls using a restriction spectrum imaging (RSI) framework that characterized total neurite density (TND), its component restricted normalized directional diffusion (RND), and restricted normalized isotropic diffusion (RNI). A significant decrease in TND was observed in autism in the right cerebellar cortex (??=??0.005, SE =0.0015, p?=?0.0267), with significant decreases in RNI and significant increases in RND found diffusely throughout posterior and anterior aspects of the brain, respectively. Furthermore, these regions remained significant in post-hoc analysis when the autism sample was compared against a subset of 1404 individuals with other psychiatric conditions (pulled from the original 8971). These findings highlight the importance of characterizing neuron cytoarchitecture in autism and the significance of their incorporation as physiological covariates in future studies. En ligne : https://doi.org/10.1002/aur.3239 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2261-2277[article] Autism is associated with in vivo changes in gray matter neurite architecture [Texte imprimé et/ou numérique] / Zachary P. CHRISTENSEN, Auteur ; Edward G. FREEDMAN, Auteur ; John J. FOXE, Auteur . - p.2261-2277.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2261-2277
Mots-clés : autism cerebellum children and adolescents cytoarchitecture DWI gray matter neurodevelopment Index. décimale : PER Périodiques Résumé : Abstract Postmortem investigations in autism have identified anomalies in neural cytoarchitecture across limbic, cerebellar, and neocortical networks. These anomalies include narrow cell mini-columns and variable neuron density. However, difficulty obtaining sufficient post-mortem samples has often prevented investigations from converging on reproducible measures. Recent advances in processing magnetic resonance diffusion weighted images (DWI) make in vivo characterization of neuronal cytoarchitecture a potential alternative to post-mortem studies. Using extensive DWI data from the Adolescent Brain Cognitive Developmentsm (ABCD?) study 142 individuals with an autism diagnosis were compared with 8971 controls using a restriction spectrum imaging (RSI) framework that characterized total neurite density (TND), its component restricted normalized directional diffusion (RND), and restricted normalized isotropic diffusion (RNI). A significant decrease in TND was observed in autism in the right cerebellar cortex (??=??0.005, SE =0.0015, p?=?0.0267), with significant decreases in RNI and significant increases in RND found diffusely throughout posterior and anterior aspects of the brain, respectively. Furthermore, these regions remained significant in post-hoc analysis when the autism sample was compared against a subset of 1404 individuals with other psychiatric conditions (pulled from the original 8971). These findings highlight the importance of characterizing neuron cytoarchitecture in autism and the significance of their incorporation as physiological covariates in future studies. En ligne : https://doi.org/10.1002/aur.3239 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : The relationship between distress tolerance and behavioral activation on anxiety and depression symptomatology in autistic youth: Leveraging self and caregiver perspectives Type de document : Texte imprimé et/ou numérique Auteurs : Jessica M. SCHWARTZMAN, Auteur ; Ligia ANTEZANA, Auteur ; Caitlin M. CONNER, Auteur Article en page(s) : p.2278-2291 Langues : Anglais (eng) Mots-clés : adolescent anxiety autism behavioral activation depression distress tolerance Index. décimale : PER Périodiques Résumé : Abstract Anxiety and depression are prevalent among autistic adolescents and may be difficult to accurately diagnose and treat given various factors (e.g., diagnostic overshadowing, heterogeneity). Therefore, efforts to examine transdiagnostic factors (i.e., distress tolerance, behavioral activation) may afford more parsimonious means for assessment and treatment. To our knowledge, there has been little research on distress tolerance, behavioral activation, and depressive and anxiety symptoms in autistic adolescents to guide diagnostic practices and treatment planning. In the current study, we examined the interrelationships between these transdiagnostic factors and depressive and anxiety symptoms using ratings from 100 verbally fluent autistic adolescents without intellectual disability (Mage?=?13.70, SDage?=?2.23, Range: 11:00?17:11?years) and 100 of their caregivers. Many adolescents reported male sex assigned at birth (61%), cisgender (87%), not Hispanic/Latinx (90%), and White (80%) identities. A series of correlational analyses were employed to examine associations between these constructs from youth and caregiver perspectives, and multiple linear regression analyses were conducted to explore the mediating roles of distress tolerance and behavioral activation. Preliminary results show that low distress tolerance and behavioral activation were associated with more severe internalizing symptoms per self- and caregiver-report. Some differences by rater emerged, which highlight the importance of multi-informant ratings in autism. Results from mediation analyses may show that behavioral activation may be more salient to assessments and treatment planning for depression than distress tolerance, while distress tolerance may be important for both anxiety and depression; however, findings are preliminary given the cross-sectional nature of the data. Findings suggest that these transdiagnostic concepts may be important to individualizing treatment approaches, including the timing of certain approaches, for anxiety and/or depression in autistic adolescents. En ligne : https://doi.org/10.1002/aur.3208 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2278-2291[article] The relationship between distress tolerance and behavioral activation on anxiety and depression symptomatology in autistic youth: Leveraging self and caregiver perspectives [Texte imprimé et/ou numérique] / Jessica M. SCHWARTZMAN, Auteur ; Ligia ANTEZANA, Auteur ; Caitlin M. CONNER, Auteur . - p.2278-2291.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2278-2291
Mots-clés : adolescent anxiety autism behavioral activation depression distress tolerance Index. décimale : PER Périodiques Résumé : Abstract Anxiety and depression are prevalent among autistic adolescents and may be difficult to accurately diagnose and treat given various factors (e.g., diagnostic overshadowing, heterogeneity). Therefore, efforts to examine transdiagnostic factors (i.e., distress tolerance, behavioral activation) may afford more parsimonious means for assessment and treatment. To our knowledge, there has been little research on distress tolerance, behavioral activation, and depressive and anxiety symptoms in autistic adolescents to guide diagnostic practices and treatment planning. In the current study, we examined the interrelationships between these transdiagnostic factors and depressive and anxiety symptoms using ratings from 100 verbally fluent autistic adolescents without intellectual disability (Mage?=?13.70, SDage?=?2.23, Range: 11:00?17:11?years) and 100 of their caregivers. Many adolescents reported male sex assigned at birth (61%), cisgender (87%), not Hispanic/Latinx (90%), and White (80%) identities. A series of correlational analyses were employed to examine associations between these constructs from youth and caregiver perspectives, and multiple linear regression analyses were conducted to explore the mediating roles of distress tolerance and behavioral activation. Preliminary results show that low distress tolerance and behavioral activation were associated with more severe internalizing symptoms per self- and caregiver-report. Some differences by rater emerged, which highlight the importance of multi-informant ratings in autism. Results from mediation analyses may show that behavioral activation may be more salient to assessments and treatment planning for depression than distress tolerance, while distress tolerance may be important for both anxiety and depression; however, findings are preliminary given the cross-sectional nature of the data. Findings suggest that these transdiagnostic concepts may be important to individualizing treatment approaches, including the timing of certain approaches, for anxiety and/or depression in autistic adolescents. En ligne : https://doi.org/10.1002/aur.3208 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : Metaphor comprehension and production in verbally able children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Stella LAMPRI, Auteur ; Eleni PERISTERI, Auteur ; Theodoros MARINIS, Auteur ; Maria ANDREOU, Auteur Article en page(s) : p.2292-2304 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder error analysis executive functions figurative language language skills metaphor production pragmatics predicate metaphors Index. décimale : PER Périodiques Résumé : Abstract Research in the field of figurative language processing in Autism Spectrum Disorders (ASD) has demonstrated that autistic individuals experience systematic difficulties in the comprehension of different types of metaphors. However, there is scarce evidence regarding metaphor production skills in ASD. Importantly, the exact source of metaphor processing difficulties in ASD remains largely controversial. The debate has mainly focused on the mediating role of structural language skills (i.e., lexical knowledge) and cognitive abilities (i.e., Theory of Mind and executive functions) in ASD individuals' ability to comprehend and generate metaphors. The present study examines metaphor comprehension and production in 18 Greek-speaking verbally able children with ASD and 31 typically-developing (TD) controls. Participants completed two tasks, namely, a low-verbal multiple-choice sentence-picture matching task that tested their ability to comprehend conventional predicate metaphors, and a sentence continuation task that assessed their ability to generate metaphors. The study also included measures of fluid intelligence, expressive vocabulary, and working memory within the sample. The results show that the ASD group had significantly lower performance than the TD group in both metaphor comprehension and production. The findings also reveal that expressive vocabulary skills were a key factor in the metaphor comprehension and production performance of the children with ASD. Working memory capacity was also found to correlate significantly with metaphor comprehension performance in the ASD group. Conversely, no correlations were found in the TD group with neither of the above factors. Of note, children with ASD generated significantly more inappropriate responses and no-responses to the metaphor production task compared with the control group. The overall results reveal that children with ASD had difficulty with both comprehending and using metaphorical language. The findings also indicate that TD children may employ diverse cognitive strategies or rely on different underlying skills when processing metaphors compared with children with ASD. En ligne : https://doi.org/10.1002/aur.3210 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2292-2304[article] Metaphor comprehension and production in verbally able children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Stella LAMPRI, Auteur ; Eleni PERISTERI, Auteur ; Theodoros MARINIS, Auteur ; Maria ANDREOU, Auteur . - p.2292-2304.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2292-2304
Mots-clés : Autism Spectrum Disorder error analysis executive functions figurative language language skills metaphor production pragmatics predicate metaphors Index. décimale : PER Périodiques Résumé : Abstract Research in the field of figurative language processing in Autism Spectrum Disorders (ASD) has demonstrated that autistic individuals experience systematic difficulties in the comprehension of different types of metaphors. However, there is scarce evidence regarding metaphor production skills in ASD. Importantly, the exact source of metaphor processing difficulties in ASD remains largely controversial. The debate has mainly focused on the mediating role of structural language skills (i.e., lexical knowledge) and cognitive abilities (i.e., Theory of Mind and executive functions) in ASD individuals' ability to comprehend and generate metaphors. The present study examines metaphor comprehension and production in 18 Greek-speaking verbally able children with ASD and 31 typically-developing (TD) controls. Participants completed two tasks, namely, a low-verbal multiple-choice sentence-picture matching task that tested their ability to comprehend conventional predicate metaphors, and a sentence continuation task that assessed their ability to generate metaphors. The study also included measures of fluid intelligence, expressive vocabulary, and working memory within the sample. The results show that the ASD group had significantly lower performance than the TD group in both metaphor comprehension and production. The findings also reveal that expressive vocabulary skills were a key factor in the metaphor comprehension and production performance of the children with ASD. Working memory capacity was also found to correlate significantly with metaphor comprehension performance in the ASD group. Conversely, no correlations were found in the TD group with neither of the above factors. Of note, children with ASD generated significantly more inappropriate responses and no-responses to the metaphor production task compared with the control group. The overall results reveal that children with ASD had difficulty with both comprehending and using metaphorical language. The findings also indicate that TD children may employ diverse cognitive strategies or rely on different underlying skills when processing metaphors compared with children with ASD. En ligne : https://doi.org/10.1002/aur.3210 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : The effect of volatility in linguistic input on prediction behavior in autistic toddlers Type de document : Texte imprimé et/ou numérique Auteurs : Kathryn E. PRESCOTT, Auteur ; Janine MATHÉE-SCOTT, Auteur ; Daniel BOLT, Auteur ; Jenny SAFFRAN, Auteur ; Susan ELLIS WEISMER, Auteur Article en page(s) : p.2305-2318 Langues : Anglais (eng) Mots-clés : autistic disorder child language cognition individuality probability learning Index. décimale : PER Périodiques Résumé : Abstract Domain-general prediction differences have been posited as underlying many aspects of the cognitive-behavioral profile in autism. An interesting potential implication of such differences is hyperplasticity of learning?the idea that autistic individuals may privilege more recent input over the accumulation of prior learning. Because real world language input is highly variable, hyperplasticity could have serious ramifications for language learning. To investigate potential hyperplasticity during a language processing task, we administered an experimental anticipatory eye movement (AEM) task to 2- to 3-year-old autistic children and neurotypical (NT) peers. Autistic children's change in anticipation from before to after a switch in contingencies did not significantly differ from NT counterparts, failing to support claims of hyperplasticity in the linguistic domain. Analysis of individual differences among autistic children revealed that cognitive ability was associated with prediction of the initial, stable contingencies, but neither age nor receptive language related to task performance. Results are discussed in terms of clinical implications and the broader context of research investigating prediction differences in autism. En ligne : https://doi.org/10.1002/aur.3212 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2305-2318[article] The effect of volatility in linguistic input on prediction behavior in autistic toddlers [Texte imprimé et/ou numérique] / Kathryn E. PRESCOTT, Auteur ; Janine MATHÉE-SCOTT, Auteur ; Daniel BOLT, Auteur ; Jenny SAFFRAN, Auteur ; Susan ELLIS WEISMER, Auteur . - p.2305-2318.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2305-2318
Mots-clés : autistic disorder child language cognition individuality probability learning Index. décimale : PER Périodiques Résumé : Abstract Domain-general prediction differences have been posited as underlying many aspects of the cognitive-behavioral profile in autism. An interesting potential implication of such differences is hyperplasticity of learning?the idea that autistic individuals may privilege more recent input over the accumulation of prior learning. Because real world language input is highly variable, hyperplasticity could have serious ramifications for language learning. To investigate potential hyperplasticity during a language processing task, we administered an experimental anticipatory eye movement (AEM) task to 2- to 3-year-old autistic children and neurotypical (NT) peers. Autistic children's change in anticipation from before to after a switch in contingencies did not significantly differ from NT counterparts, failing to support claims of hyperplasticity in the linguistic domain. Analysis of individual differences among autistic children revealed that cognitive ability was associated with prediction of the initial, stable contingencies, but neither age nor receptive language related to task performance. Results are discussed in terms of clinical implications and the broader context of research investigating prediction differences in autism. En ligne : https://doi.org/10.1002/aur.3212 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : Motor, cognitive, and socio-cognitive mechanisms explaining social skills in autism and typical development Type de document : Texte imprimé et/ou numérique Auteurs : Yael ESTRUGO, Auteur ; Shahar BAR YEHUDA, Auteur ; Nirit BAUMINGER-ZVIELY, Auteur Article en page(s) : p.2319-2332 Langues : Anglais (eng) Mots-clés : autism executive functioning motor skills social skills theory of mind Index. décimale : PER Périodiques Résumé : Abstract Challenges in social functioning are considered a core criterion for diagnosing autism. Although motor skills, executive functioning (EF), and theory of mind (ToM) abilities independently affect social challenges and are interconnected, these abilities' shared contribution to the explanation of social functioning in autism remains under-investigated. To address this disparity, we examined the motor, EF, and ToM abilities of 148 autistic and non-autistic youth (ages 6?16?years), evaluating these variables' impact on social ability and their interconnections. Our mediation model exploring the contribution of motor, EF, and ToM skills explained 85% of the variance in social functioning (Social Responsiveness Scale?SRS-2). Analysis yielded a direct path from study group to SRS-2-social (typically developing-TD?>?autistic) and two main parallel indirect joint paths: (a) Group???motor???EF???SRS-2-social; and (b) Group???motor???ToM???SRS-2-social. In two secondary indirect paths, autistic children showed lower motor skills, which in turn explained their higher EF and/or ToM impairment, which in turn explained their higher social skills impairment. Put differently, our results suggest that better EF and TOM proficiency may compensate for poorer motor skills. Findings also indicated that the collective impact of motor, EF, and ToM skills on social functioning, along with the mediating role played by EF and ToM on the social-motor linkage, may contribute to understanding individual differences in the social functioning of autistic children. These conclusions call for the inclusion of motor, EF, and ToM activities into daily practices to facilitate social functioning. En ligne : https://doi.org/10.1002/aur.3215 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2319-2332[article] Motor, cognitive, and socio-cognitive mechanisms explaining social skills in autism and typical development [Texte imprimé et/ou numérique] / Yael ESTRUGO, Auteur ; Shahar BAR YEHUDA, Auteur ; Nirit BAUMINGER-ZVIELY, Auteur . - p.2319-2332.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2319-2332
Mots-clés : autism executive functioning motor skills social skills theory of mind Index. décimale : PER Périodiques Résumé : Abstract Challenges in social functioning are considered a core criterion for diagnosing autism. Although motor skills, executive functioning (EF), and theory of mind (ToM) abilities independently affect social challenges and are interconnected, these abilities' shared contribution to the explanation of social functioning in autism remains under-investigated. To address this disparity, we examined the motor, EF, and ToM abilities of 148 autistic and non-autistic youth (ages 6?16?years), evaluating these variables' impact on social ability and their interconnections. Our mediation model exploring the contribution of motor, EF, and ToM skills explained 85% of the variance in social functioning (Social Responsiveness Scale?SRS-2). Analysis yielded a direct path from study group to SRS-2-social (typically developing-TD?>?autistic) and two main parallel indirect joint paths: (a) Group???motor???EF???SRS-2-social; and (b) Group???motor???ToM???SRS-2-social. In two secondary indirect paths, autistic children showed lower motor skills, which in turn explained their higher EF and/or ToM impairment, which in turn explained their higher social skills impairment. Put differently, our results suggest that better EF and TOM proficiency may compensate for poorer motor skills. Findings also indicated that the collective impact of motor, EF, and ToM skills on social functioning, along with the mediating role played by EF and ToM on the social-motor linkage, may contribute to understanding individual differences in the social functioning of autistic children. These conclusions call for the inclusion of motor, EF, and ToM activities into daily practices to facilitate social functioning. En ligne : https://doi.org/10.1002/aur.3215 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : More similar than different: Characterizing special interests in autistic boys and girls based on caregiver report Type de document : Texte imprimé et/ou numérique Auteurs : Cynthia E. BROWN, Auteur ; Courtney J. BERNARDIN, Auteur ; Marshall T. BEAUCHAMP, Auteur ; Stephen M. KANNE, Auteur ; Kerri P. NOWELL, Auteur Article en page(s) : p.2333-2345 Langues : Anglais (eng) Mots-clés : gender differences gender/female autism restrictive/repetitive behaviors Index. décimale : PER Périodiques Résumé : Abstract Almost all autistic youths have special interests (SIs), which are focused, intense areas of passion and interest in a particular topic. Emerging research suggests that there are gender differences in SIs among autistic youth; however, commonly used measures that assess for the presence of SIs may not fully capture the granular nature of those differences between autistic boys and girls. Characterizing these differences is important for autism identification in girls, as SIs in autistic girls may often be overlooked by caregivers, teachers, and clinicians due to their more ?typical? and more socially oriented content areas compared to autistic boys. This study therefore aimed to more fully characterize gender differences in SIs using a newly developed caregiver-report measure of SIs (the Special Interests Survey; SIS). Caregivers of 1921 autistic youth completed the SIS. Analyses revealed many similarities between boys and girls; there were no gender differences in mean age SI onset, caregivers' perceptions of uniqueness or interferences of endorsed SIs, or duration of previous SIs. There were gender differences in endorsement of less than half (39%) of the SI categories measured, and there were minor differences in the number of endorsed current and past SIs. Categories with significant gender differences fell along typical gender lines (e.g., more boys interested in math and construction, more girls interested in animals and arts/crafts). This study extends the growing literature on SIs and gender differences in autism and has important implications for supporting autistic youth and their families. En ligne : https://doi.org/10.1002/aur.3216 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2333-2345[article] More similar than different: Characterizing special interests in autistic boys and girls based on caregiver report [Texte imprimé et/ou numérique] / Cynthia E. BROWN, Auteur ; Courtney J. BERNARDIN, Auteur ; Marshall T. BEAUCHAMP, Auteur ; Stephen M. KANNE, Auteur ; Kerri P. NOWELL, Auteur . - p.2333-2345.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2333-2345
Mots-clés : gender differences gender/female autism restrictive/repetitive behaviors Index. décimale : PER Périodiques Résumé : Abstract Almost all autistic youths have special interests (SIs), which are focused, intense areas of passion and interest in a particular topic. Emerging research suggests that there are gender differences in SIs among autistic youth; however, commonly used measures that assess for the presence of SIs may not fully capture the granular nature of those differences between autistic boys and girls. Characterizing these differences is important for autism identification in girls, as SIs in autistic girls may often be overlooked by caregivers, teachers, and clinicians due to their more ?typical? and more socially oriented content areas compared to autistic boys. This study therefore aimed to more fully characterize gender differences in SIs using a newly developed caregiver-report measure of SIs (the Special Interests Survey; SIS). Caregivers of 1921 autistic youth completed the SIS. Analyses revealed many similarities between boys and girls; there were no gender differences in mean age SI onset, caregivers' perceptions of uniqueness or interferences of endorsed SIs, or duration of previous SIs. There were gender differences in endorsement of less than half (39%) of the SI categories measured, and there were minor differences in the number of endorsed current and past SIs. Categories with significant gender differences fell along typical gender lines (e.g., more boys interested in math and construction, more girls interested in animals and arts/crafts). This study extends the growing literature on SIs and gender differences in autism and has important implications for supporting autistic youth and their families. En ligne : https://doi.org/10.1002/aur.3216 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : Parent-mediated intervention in infants with an elevated likelihood for autism reduces dwell time during a gaze-following task Type de document : Texte imprimé et/ou numérique Auteurs : Rachael BEDFORD, Auteur ; Jonathan GREEN, Auteur ; Teodora GLIGA, Auteur ; Emily H. JONES, Auteur ; Mayada ELSABBAGH, Auteur ; Greg PASCO, Auteur ; Ming Wai WAN, Auteur ; Vicky SLONIMS, Auteur ; Tony CHARMAN, Auteur ; Andrew PICKLES, Auteur ; Mark H. JOHNSON, Auteur ; Basis Team THE, Auteur Article en page(s) : p.2346-2354 Langues : Anglais (eng) Mots-clés : autism elevated likelihood for autism gaze following infant siblings intervention parent-mediated intervention RCT Index. décimale : PER Périodiques Résumé : Abstract Cognitive markers may in theory be more sensitive to the effects of intervention than overt behavioral measures. The current study tests the impact of the Intervention with the British Autism Study of Infant Siblings?Video Interaction for Promoting Positive Parenting (iBASIS-VIPP) on an eye-tracking measure of social attention: dwell time to the referred object in a gaze following task. The original two-site, two-arm, assessor-blinded randomized controlled trial (RCT) of this intervention to increase parental awareness, and responsiveness to their infant, was run with infants who have an elevated familial likelihood for autism (EL). Fifty-four EL infants (28 iBASIS-VIPP intervention, 26 no intervention) were enrolled, and the intervention took place between 9?months (baseline) and 15?months (endpoint), with gaze following behavior measured at 15?months. Secondary intention to treat (ITT) analysis showed that the intervention was associated with significantly reduced dwell time to the referent of another person's gaze (??=??0.32, SE?=?0.14, p?=?0.03) at 15-month treatment endpoint. Given the established link between gaze following and language, the results are considered in the context of a previously reported, non-significant and transient trend toward lower language scores at the treatment endpoint (Green et al. (2015) The Lancet Psychiatry, 2(2), 133?140). Future intervention trials should aim to include experimental cognitive measures, alongside behavioral measures, to investigate mechanisms associated with intervention effects. En ligne : https://doi.org/10.1002/aur.3223 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2346-2354[article] Parent-mediated intervention in infants with an elevated likelihood for autism reduces dwell time during a gaze-following task [Texte imprimé et/ou numérique] / Rachael BEDFORD, Auteur ; Jonathan GREEN, Auteur ; Teodora GLIGA, Auteur ; Emily H. JONES, Auteur ; Mayada ELSABBAGH, Auteur ; Greg PASCO, Auteur ; Ming Wai WAN, Auteur ; Vicky SLONIMS, Auteur ; Tony CHARMAN, Auteur ; Andrew PICKLES, Auteur ; Mark H. JOHNSON, Auteur ; Basis Team THE, Auteur . - p.2346-2354.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2346-2354
Mots-clés : autism elevated likelihood for autism gaze following infant siblings intervention parent-mediated intervention RCT Index. décimale : PER Périodiques Résumé : Abstract Cognitive markers may in theory be more sensitive to the effects of intervention than overt behavioral measures. The current study tests the impact of the Intervention with the British Autism Study of Infant Siblings?Video Interaction for Promoting Positive Parenting (iBASIS-VIPP) on an eye-tracking measure of social attention: dwell time to the referred object in a gaze following task. The original two-site, two-arm, assessor-blinded randomized controlled trial (RCT) of this intervention to increase parental awareness, and responsiveness to their infant, was run with infants who have an elevated familial likelihood for autism (EL). Fifty-four EL infants (28 iBASIS-VIPP intervention, 26 no intervention) were enrolled, and the intervention took place between 9?months (baseline) and 15?months (endpoint), with gaze following behavior measured at 15?months. Secondary intention to treat (ITT) analysis showed that the intervention was associated with significantly reduced dwell time to the referent of another person's gaze (??=??0.32, SE?=?0.14, p?=?0.03) at 15-month treatment endpoint. Given the established link between gaze following and language, the results are considered in the context of a previously reported, non-significant and transient trend toward lower language scores at the treatment endpoint (Green et al. (2015) The Lancet Psychiatry, 2(2), 133?140). Future intervention trials should aim to include experimental cognitive measures, alongside behavioral measures, to investigate mechanisms associated with intervention effects. En ligne : https://doi.org/10.1002/aur.3223 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : Transitive inference in a clinical childhood sample with a focus on autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Tina KAO, Auteur ; Charlotte MICHAELCHECK, Auteur ; Vincent P. FERRERA, Auteur ; Herbert S. TERRACE, Auteur ; Greg JENSEN, Auteur Article en page(s) : p.2355-2369 Langues : Anglais (eng) Mots-clés : autism spectrum disorder cognition humans learning serial learning transitive inference Index. décimale : PER Périodiques Résumé : Abstract Transitive inference (TI) has a long history in the study of human development. There have, however, few pediatric studies that report clinical diagnoses have tested trial-and-error TI learning, in which participants infer item relations, rather than evaluate them explicitly from verbal descriptions. Children aged 8?10 underwent a battery of clinical assessments and received a range of diagnoses, potentially including autism spectrum disorder (ASD), attention-deficit hyperactive disorder (ADHD), anxiety disorders (AD), specific learning disorders (SLD), and/or communication disorders (CD). Participants also performed a trial-and-error learning task that tested for TI. Response accuracy and reaction time were assessed using a statistical model that controlled for diagnostic comorbidity at the group level. Participants in all diagnostic categories showed evidence of TI. However, a model comparison analysis suggested that those diagnosed with ASD succeeded in a qualitatively different way, responding more slowly to each choice and improving faster across trials than their non-ASD counterparts. Additionally, TI performance was not associated with IQ. Overall, our data suggest that superficially similar performance levels between ASD and non-ASD participants may have resulted from a difference in the speed-accuracy tradeoff made by each group. Our work provides a preliminary profile of the impact of various clinical diagnoses on TI performance in young children. Of these, an ASD diagnosis resulted in the largest difference in task strategy. En ligne : https://doi.org/10.1002/aur.3225 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2355-2369[article] Transitive inference in a clinical childhood sample with a focus on autism spectrum disorder [Texte imprimé et/ou numérique] / Tina KAO, Auteur ; Charlotte MICHAELCHECK, Auteur ; Vincent P. FERRERA, Auteur ; Herbert S. TERRACE, Auteur ; Greg JENSEN, Auteur . - p.2355-2369.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2355-2369
Mots-clés : autism spectrum disorder cognition humans learning serial learning transitive inference Index. décimale : PER Périodiques Résumé : Abstract Transitive inference (TI) has a long history in the study of human development. There have, however, few pediatric studies that report clinical diagnoses have tested trial-and-error TI learning, in which participants infer item relations, rather than evaluate them explicitly from verbal descriptions. Children aged 8?10 underwent a battery of clinical assessments and received a range of diagnoses, potentially including autism spectrum disorder (ASD), attention-deficit hyperactive disorder (ADHD), anxiety disorders (AD), specific learning disorders (SLD), and/or communication disorders (CD). Participants also performed a trial-and-error learning task that tested for TI. Response accuracy and reaction time were assessed using a statistical model that controlled for diagnostic comorbidity at the group level. Participants in all diagnostic categories showed evidence of TI. However, a model comparison analysis suggested that those diagnosed with ASD succeeded in a qualitatively different way, responding more slowly to each choice and improving faster across trials than their non-ASD counterparts. Additionally, TI performance was not associated with IQ. Overall, our data suggest that superficially similar performance levels between ASD and non-ASD participants may have resulted from a difference in the speed-accuracy tradeoff made by each group. Our work provides a preliminary profile of the impact of various clinical diagnoses on TI performance in young children. Of these, an ASD diagnosis resulted in the largest difference in task strategy. En ligne : https://doi.org/10.1002/aur.3225 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : Profiles of nonverbal skills used by young pre-verbal children with autism on the ADOS-2: Relation to screening disposition and outcomes Type de document : Texte imprimé et/ou numérique Auteurs : Lisa R. HAMRICK, Auteur ; Rosmary ROS-DEMARIZE, Auteur ; Stephen KANNE, Auteur ; Laura Arnstein CARPENTER, Auteur Article en page(s) : p.2370-2385 Langues : Anglais (eng) Mots-clés : assessment autism diagnosis latent class analysis nonverbal communication screening Index. décimale : PER Périodiques Résumé : Abstract Autistic individuals exhibit differences in their use and understanding of nonverbal communication; however, individual patterns of nonverbal strengths and challenges vary significantly. This heterogeneity can complicate the diagnostic and screening processes and can result in delayed or missed diagnoses. In this study, we characterize various profiles of nonverbal communication skills among 215 pre-verbal children with autism (Mage?=?36.27?months, range?=?18?70) and explore how these profiles are related to screening outcomes, diagnostic certainty, and developmental and behavioral features. We conducted a latent class analysis of nine items assessing nonverbal communication skills from the Toddler Module and Module 1 of the Autism Diagnostic Observation Schedule, 2nd Edition. Five nonverbal profiles were identified that differentiated children based on the form, function, and frequency of their nonverbal communication skills. Furthermore, screening outcomes and clinician certainty in autism diagnosis varied by nonverbal profile. False negative screening outcomes based on parent report were highest for children who used a range of nonverbal skills but with limited frequency or consistency. Clinicians, on the other hand, tended to have high certainty in an autism diagnosis for children with this profile, and instead rated their lowest certainty in diagnosing children who demonstrated consistent integration of eye contact with their nonverbal communication. The profiles identified in this study could be clinically useful in helping to identify children at highest likelihood of being overlooked during the screening or diagnostic processes, providing an opportunity to improve early identification and intervention for autism. En ligne : https://doi.org/10.1002/aur.3229 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2370-2385[article] Profiles of nonverbal skills used by young pre-verbal children with autism on the ADOS-2: Relation to screening disposition and outcomes [Texte imprimé et/ou numérique] / Lisa R. HAMRICK, Auteur ; Rosmary ROS-DEMARIZE, Auteur ; Stephen KANNE, Auteur ; Laura Arnstein CARPENTER, Auteur . - p.2370-2385.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2370-2385
Mots-clés : assessment autism diagnosis latent class analysis nonverbal communication screening Index. décimale : PER Périodiques Résumé : Abstract Autistic individuals exhibit differences in their use and understanding of nonverbal communication; however, individual patterns of nonverbal strengths and challenges vary significantly. This heterogeneity can complicate the diagnostic and screening processes and can result in delayed or missed diagnoses. In this study, we characterize various profiles of nonverbal communication skills among 215 pre-verbal children with autism (Mage?=?36.27?months, range?=?18?70) and explore how these profiles are related to screening outcomes, diagnostic certainty, and developmental and behavioral features. We conducted a latent class analysis of nine items assessing nonverbal communication skills from the Toddler Module and Module 1 of the Autism Diagnostic Observation Schedule, 2nd Edition. Five nonverbal profiles were identified that differentiated children based on the form, function, and frequency of their nonverbal communication skills. Furthermore, screening outcomes and clinician certainty in autism diagnosis varied by nonverbal profile. False negative screening outcomes based on parent report were highest for children who used a range of nonverbal skills but with limited frequency or consistency. Clinicians, on the other hand, tended to have high certainty in an autism diagnosis for children with this profile, and instead rated their lowest certainty in diagnosing children who demonstrated consistent integration of eye contact with their nonverbal communication. The profiles identified in this study could be clinically useful in helping to identify children at highest likelihood of being overlooked during the screening or diagnostic processes, providing an opportunity to improve early identification and intervention for autism. En ligne : https://doi.org/10.1002/aur.3229 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : Sleep disturbance and other co-occurring conditions in autistic children: A network approach to understanding their inter-relationships Type de document : Texte imprimé et/ou numérique Auteurs : Amanda L. RICHDALE, Auteur ; Amy M. SHUI, Auteur ; Linnea A. LAMPINEN, Auteur ; Terry KATZ, Auteur Article en page(s) : p.2386-2404 Langues : Anglais (eng) Mots-clés : aggression autism network analysis sleep disturbance transdiagnostic Index. décimale : PER Périodiques Résumé : Abstract Autistic children frequently have one or more co-occurring psychological, behavioral, or medical conditions. We examined relationships between child behaviors, sleep, adaptive behavior, autistic traits, mental health conditions, and health in autistic children using network analysis. Network analysis is hypothesis generating and can inform our understanding of relationships between multiple conditions and behaviors, directing the development of transdiagnostic treatments for co-occurring conditions. Participants were two child cohorts from the Autism Treatment Network registry: ages 2?5?years (n?=?2372) and 6?17?years (n?=?1553). Least absolute-shrinkage and selection operator (LASSO) regularized partial correlation network analysis was performed in the 2?5?years cohort (35 items) and the 6?17?years cohort (36 items). The Spinglass algorithm determined communities within each network. Two-step expected influence (EI2) determined the importance of network variables. The most influential network items were sleep difficulties (2 items) and aggressive behaviors for young children and aggressive behaviors, social problems, and anxious/depressed behavior for older children. Five communities were found for younger children and seven for older children. Of the top three most important bridge variables, night-waking/parasomnias and anxious/depressed behavior were in both age-groups, and somatic complaints and sleep initiation/duration were in younger and older cohorts respectively. Despite cohort differences, sleep disturbances were prominent in all networks, indicating they are a transdiagnostic feature across many clinical conditions, and thus a target for intervention and monitoring. Aggressive behavior was influential in the partial correlation networks, indicating a potential red flag for clinical monitoring. Other items of strong network importance may also be intervention targets or screening flags. En ligne : https://doi.org/10.1002/aur.3233 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2386-2404[article] Sleep disturbance and other co-occurring conditions in autistic children: A network approach to understanding their inter-relationships [Texte imprimé et/ou numérique] / Amanda L. RICHDALE, Auteur ; Amy M. SHUI, Auteur ; Linnea A. LAMPINEN, Auteur ; Terry KATZ, Auteur . - p.2386-2404.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2386-2404
Mots-clés : aggression autism network analysis sleep disturbance transdiagnostic Index. décimale : PER Périodiques Résumé : Abstract Autistic children frequently have one or more co-occurring psychological, behavioral, or medical conditions. We examined relationships between child behaviors, sleep, adaptive behavior, autistic traits, mental health conditions, and health in autistic children using network analysis. Network analysis is hypothesis generating and can inform our understanding of relationships between multiple conditions and behaviors, directing the development of transdiagnostic treatments for co-occurring conditions. Participants were two child cohorts from the Autism Treatment Network registry: ages 2?5?years (n?=?2372) and 6?17?years (n?=?1553). Least absolute-shrinkage and selection operator (LASSO) regularized partial correlation network analysis was performed in the 2?5?years cohort (35 items) and the 6?17?years cohort (36 items). The Spinglass algorithm determined communities within each network. Two-step expected influence (EI2) determined the importance of network variables. The most influential network items were sleep difficulties (2 items) and aggressive behaviors for young children and aggressive behaviors, social problems, and anxious/depressed behavior for older children. Five communities were found for younger children and seven for older children. Of the top three most important bridge variables, night-waking/parasomnias and anxious/depressed behavior were in both age-groups, and somatic complaints and sleep initiation/duration were in younger and older cohorts respectively. Despite cohort differences, sleep disturbances were prominent in all networks, indicating they are a transdiagnostic feature across many clinical conditions, and thus a target for intervention and monitoring. Aggressive behavior was influential in the partial correlation networks, indicating a potential red flag for clinical monitoring. Other items of strong network importance may also be intervention targets or screening flags. En ligne : https://doi.org/10.1002/aur.3233 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : Longitudinal change in symptom severity in children with ASD: Results from the ELENA cohort Type de document : Texte imprimé et/ou numérique Auteurs : Florine DELLAPIAZZA, Auteur ; Cécile RATTAZ, Auteur ; Cécile MICHELON, Auteur ; Hugo PEYRE, Auteur ; Marie-Christine PICOT, Auteur ; Amaria BAGHDADLI, Auteur Article en page(s) : p.2405-2417 Langues : Anglais (eng) Mots-clés : ADOS-CSS autism Spectrum disorders cohort follow-up severity Index. décimale : PER Périodiques Résumé : Abstract Autism spectrum disorder (ASD) is a lifelong neurodevelopmental condition and understanding the changes in autism symptoms over time is crucial for tailoring support and interventions. This study therefore aimed to investigate the changes in symptom severity in a large cohort of children with ASD over a three-year follow-up period and identify factors that influence these changes. The study included 575 children diagnosed with ASD, ranging in age from 2 to 12?years, who were assessed at baseline and again 3?years later using the Autism Diagnostic Observational Schedule-2 (ADOS-2). ASD severity changes were investigated using the ADOS calibrated severity score (CSS) scores for total, social affect (SA) and restricted and repetitive behaviors (RRB). Results highlight four distinct patterns: stable high, stable low, increased, and decreased severity. The ADOS CSS total score changed for half of the sample, reflecting an increase in ASD severity for 21.9% and a decrease for 29.1% of children. For the other half, the ADOS CSS score remained stable, either high (34.4%) or low (14.6%). While the majority of previous studies reported stability in ASD severity, our findings revealed significant variability with frequent improvements in SA symptoms whereas RRBs remained stable or worsened. Our findings also showed that an improvement in SA was associated with the youngest group and early diagnosis. However, no clinical or sociodemographic factors were linked to changes in RRB, emphasizing the necessity for RRB-specific therapies. The third six-year follow-up point of the ongoing ELENA cohort study will map the long-term trajectories of the severity of ASD symptoms and their potential risk factors. En ligne : https://doi.org/10.1002/aur.3242 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2405-2417[article] Longitudinal change in symptom severity in children with ASD: Results from the ELENA cohort [Texte imprimé et/ou numérique] / Florine DELLAPIAZZA, Auteur ; Cécile RATTAZ, Auteur ; Cécile MICHELON, Auteur ; Hugo PEYRE, Auteur ; Marie-Christine PICOT, Auteur ; Amaria BAGHDADLI, Auteur . - p.2405-2417.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2405-2417
Mots-clés : ADOS-CSS autism Spectrum disorders cohort follow-up severity Index. décimale : PER Périodiques Résumé : Abstract Autism spectrum disorder (ASD) is a lifelong neurodevelopmental condition and understanding the changes in autism symptoms over time is crucial for tailoring support and interventions. This study therefore aimed to investigate the changes in symptom severity in a large cohort of children with ASD over a three-year follow-up period and identify factors that influence these changes. The study included 575 children diagnosed with ASD, ranging in age from 2 to 12?years, who were assessed at baseline and again 3?years later using the Autism Diagnostic Observational Schedule-2 (ADOS-2). ASD severity changes were investigated using the ADOS calibrated severity score (CSS) scores for total, social affect (SA) and restricted and repetitive behaviors (RRB). Results highlight four distinct patterns: stable high, stable low, increased, and decreased severity. The ADOS CSS total score changed for half of the sample, reflecting an increase in ASD severity for 21.9% and a decrease for 29.1% of children. For the other half, the ADOS CSS score remained stable, either high (34.4%) or low (14.6%). While the majority of previous studies reported stability in ASD severity, our findings revealed significant variability with frequent improvements in SA symptoms whereas RRBs remained stable or worsened. Our findings also showed that an improvement in SA was associated with the youngest group and early diagnosis. However, no clinical or sociodemographic factors were linked to changes in RRB, emphasizing the necessity for RRB-specific therapies. The third six-year follow-up point of the ongoing ELENA cohort study will map the long-term trajectories of the severity of ASD symptoms and their potential risk factors. En ligne : https://doi.org/10.1002/aur.3242 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : Regional differences in autism and intellectual disability risk associated with cesarean section delivery Type de document : Texte imprimé et/ou numérique Auteurs : Deborah A. BILDER, Auteur ; Scott SULLIVAN, Auteur ; Michelle M. HUGHES, Auteur ; Susan DALTON, Auteur ; Jennifer HALL-LANDE, Auteur ; Connor NICHOLLS, Auteur ; Amanda V. BAKIAN, Auteur Article en page(s) : p.2418-2429 Langues : Anglais (eng) Mots-clés : autism cesarean section epidemiology intellectual disability prenatal risk factors Index. décimale : PER Périodiques Résumé : Abstract Prior epidemiological studies investigating the association between delivery mode (i.e., vaginal birth and cesarean section [C-section]) and autism spectrum disorder (ASD) and intellectual disability (ID) risk have reported mixed findings. This study examined ASD and ID risks associated with primary and repeat C-section within diverse US regions. During even years 2000?2016, 8-years-olds were identified with ASD and/or ID and matched to birth records [ASD only (N?=?8566, 83.6% male), ASD?+?ID (N?=?3445, 79.5% male), ID only (N?=?6158, 60.8% male)] using the Centers for Disease Control and Prevention's Autism and Developmental Disabilities Monitoring Network methodology. The comparison birth cohort (N?=?1,456,914, 51.1% male) comprised all births recorded in the National Center for Health Statistics corresponding to birth years and counties in which surveillance occurred. C-section rates in the birth cohort demonstrated significant regional variation with lowest rates in the West. Overall models demonstrate increased odds of disability associated with primary and repeat C-section. Adjusted models, stratified by region, identified significant variability in disability likelihood associated with repeat C-section: increased odds occurred for all case groups in the Southeast, for ASD only and ID only in the Mid-Atlantic, and no case groups in the West. Regional variability in disability risk associated with repeat C-section coincides with differences in birth cohorts' C-section rates. This suggests increased likelihood of disability is not incurred by the procedure itself, but rather C-section serves as a proxy for exposures with regional variability that influence fetal development and C-section rates. En ligne : https://doi.org/10.1002/aur.3247 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2418-2429[article] Regional differences in autism and intellectual disability risk associated with cesarean section delivery [Texte imprimé et/ou numérique] / Deborah A. BILDER, Auteur ; Scott SULLIVAN, Auteur ; Michelle M. HUGHES, Auteur ; Susan DALTON, Auteur ; Jennifer HALL-LANDE, Auteur ; Connor NICHOLLS, Auteur ; Amanda V. BAKIAN, Auteur . - p.2418-2429.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2418-2429
Mots-clés : autism cesarean section epidemiology intellectual disability prenatal risk factors Index. décimale : PER Périodiques Résumé : Abstract Prior epidemiological studies investigating the association between delivery mode (i.e., vaginal birth and cesarean section [C-section]) and autism spectrum disorder (ASD) and intellectual disability (ID) risk have reported mixed findings. This study examined ASD and ID risks associated with primary and repeat C-section within diverse US regions. During even years 2000?2016, 8-years-olds were identified with ASD and/or ID and matched to birth records [ASD only (N?=?8566, 83.6% male), ASD?+?ID (N?=?3445, 79.5% male), ID only (N?=?6158, 60.8% male)] using the Centers for Disease Control and Prevention's Autism and Developmental Disabilities Monitoring Network methodology. The comparison birth cohort (N?=?1,456,914, 51.1% male) comprised all births recorded in the National Center for Health Statistics corresponding to birth years and counties in which surveillance occurred. C-section rates in the birth cohort demonstrated significant regional variation with lowest rates in the West. Overall models demonstrate increased odds of disability associated with primary and repeat C-section. Adjusted models, stratified by region, identified significant variability in disability likelihood associated with repeat C-section: increased odds occurred for all case groups in the Southeast, for ASD only and ID only in the Mid-Atlantic, and no case groups in the West. Regional variability in disability risk associated with repeat C-section coincides with differences in birth cohorts' C-section rates. This suggests increased likelihood of disability is not incurred by the procedure itself, but rather C-section serves as a proxy for exposures with regional variability that influence fetal development and C-section rates. En ligne : https://doi.org/10.1002/aur.3247 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
Titre : Comparative effectiveness trial: Modular behavior approach for young autistic children compared to comprehensive behavioral intervention Type de document : Texte imprimé et/ou numérique Auteurs : Cynthia ANDERSON, Auteur ; Samantha HOCHHEIMER, Auteur ; Zachary WARREN, Auteur ; Eric BUTTER, Auteur ; Susan L. HYMAN, Auteur ; Hongyue WANG, Auteur ; Lisa WALLACE, Auteur ; Lynne LEVATO, Auteur ; Ryan MARTIN, Auteur ; Kevin G. STEPHENSON, Auteur ; Megan NORRIS, Auteur ; Wynn JACQUELINE, Auteur ; Tristram SMITH, Auteur ; Cynthia R. JOHNSON, Auteur Article en page(s) : p.2430-2446 Langues : Anglais (eng) Mots-clés : applied behavior analysis autism behavioral intervention comprehensive behavior intervention (CBI) discrete trial training (DTT) early intensive Behavioral intervention (EIBI) naturalistic developmental Behavioral interventions (NDBIs) noninferiority design randomized clinical trial (RCT) Index. décimale : PER Périodiques Résumé : Abstract This 24-week single-blind trial tested a modular approach for young autistic children (MAYAC) that was delivered for fewer hours per week and modified based on child progress and parental input compared to comprehensive behavioral intervention treatment as usual (CBI, TAU). Participants were autistic children, ages 18?60?months of age. MAYAC was initially 5?h of intervention per week, one of which was parent training and the other four direct therapy focusing on social communication and engagement, but additional modules could be added for up to 10?h per week. Comprehensive behavior intervention was delivered for ?15?h per week. Outcome measures included the Vineland Adaptive Behavior Scales; VABS, the Ohio Autism Clinical Improvement Scale ? Autism Severity; OACIS ? AS and the Pervasive Developmental Disorder Behavior Inventory ? Parent; PDDBI-P. Implementation and parent satisfaction measures were also collected. Fifty-six children, mean age of 34?months, were randomized. Within-group analysis revealed significant improvements from baseline to week 24 for both MAYAC (p?95%) as was parent satisfaction. Findings from this small trial are promising and suggest MAYAC may be an alternative for some young autistic children and their families to CBI, TAU. En ligne : https://doi.org/10.1002/aur.3240 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
in Autism Research > 17-11 (November 2024) . - p.2430-2446[article] Comparative effectiveness trial: Modular behavior approach for young autistic children compared to comprehensive behavioral intervention [Texte imprimé et/ou numérique] / Cynthia ANDERSON, Auteur ; Samantha HOCHHEIMER, Auteur ; Zachary WARREN, Auteur ; Eric BUTTER, Auteur ; Susan L. HYMAN, Auteur ; Hongyue WANG, Auteur ; Lisa WALLACE, Auteur ; Lynne LEVATO, Auteur ; Ryan MARTIN, Auteur ; Kevin G. STEPHENSON, Auteur ; Megan NORRIS, Auteur ; Wynn JACQUELINE, Auteur ; Tristram SMITH, Auteur ; Cynthia R. JOHNSON, Auteur . - p.2430-2446.
Langues : Anglais (eng)
in Autism Research > 17-11 (November 2024) . - p.2430-2446
Mots-clés : applied behavior analysis autism behavioral intervention comprehensive behavior intervention (CBI) discrete trial training (DTT) early intensive Behavioral intervention (EIBI) naturalistic developmental Behavioral interventions (NDBIs) noninferiority design randomized clinical trial (RCT) Index. décimale : PER Périodiques Résumé : Abstract This 24-week single-blind trial tested a modular approach for young autistic children (MAYAC) that was delivered for fewer hours per week and modified based on child progress and parental input compared to comprehensive behavioral intervention treatment as usual (CBI, TAU). Participants were autistic children, ages 18?60?months of age. MAYAC was initially 5?h of intervention per week, one of which was parent training and the other four direct therapy focusing on social communication and engagement, but additional modules could be added for up to 10?h per week. Comprehensive behavior intervention was delivered for ?15?h per week. Outcome measures included the Vineland Adaptive Behavior Scales; VABS, the Ohio Autism Clinical Improvement Scale ? Autism Severity; OACIS ? AS and the Pervasive Developmental Disorder Behavior Inventory ? Parent; PDDBI-P. Implementation and parent satisfaction measures were also collected. Fifty-six children, mean age of 34?months, were randomized. Within-group analysis revealed significant improvements from baseline to week 24 for both MAYAC (p?95%) as was parent satisfaction. Findings from this small trial are promising and suggest MAYAC may be an alternative for some young autistic children and their families to CBI, TAU. En ligne : https://doi.org/10.1002/aur.3240 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542
