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Auteur Pascal P. ARP |
Documents disponibles écrits par cet auteur (1)
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Recognition of scared faces and the serotonin transporter gene in young children: the Generation R Study / Eszter SZEKELY in Journal of Child Psychology and Psychiatry, 52-12 (December 2011)
[article]
Titre : Recognition of scared faces and the serotonin transporter gene in young children: the Generation R Study Type de document : Texte imprimé et/ou numérique Auteurs : Eszter SZEKELY, Auteur ; Catherine M. HERBA, Auteur ; Pascal P. ARP, Auteur ; André G. UITTERLINDEN, Auteur ; Vincent W.V. JADDOE, Auteur ; Albert HOFMAN, Auteur ; Frank C. VERHULST, Auteur ; James J. HUDZIAK, Auteur ; Henning TIEMEIER, Auteur Année de publication : 2011 Article en page(s) : p.1279-1286 Langues : Anglais (eng) Mots-clés : Serotonin transporter gene emotion processing facial expression fear children Index. décimale : PER Périodiques Résumé : Background: Previous research highlights the significance of a functional polymorphism located in the promoter region (5-HTTLPR) of the serotonin transporter gene in emotional behaviour. This study examined the effect of the 5-HTTLPR polymorphism on emotion processing in a large number of healthy preschoolers.
Methods: The 5-HTTLPR genotype was classified in 605 children as homozygous for the short allele (SS), homozygous for the long allele (LL), or heterozygous (LS). Emotion-processing was assessed using age-appropriate computer tasks where children matched happy, sad, angry, and fearful facial expressions preceded by a shape-matching task to assess basic matching ability.
Results: We found that young children could differentiate between emotion categories (F = 12.1, p < .001). The effect of 5-HTTLPR genotype depended on the emotion category presented (F = 2.3, p = .031). This effect was explained by the finding that SS children were less accurate at recognising fearful faces than LL or LS children (F = 5.3, p = .005). We did not find any significant differences as a result of 5-HTTLPR genotype for happy, sad or angry expressions (p > .05).
Conclusions: Results indicate that 5-HTTLPR allele status selectively impacts the processing of fearful but not other facial expressions. This pattern is already apparent in very young typically developing children. Results may signal an early vulnerability for affective problems before disorders emerge.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02423.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=146
in Journal of Child Psychology and Psychiatry > 52-12 (December 2011) . - p.1279-1286[article] Recognition of scared faces and the serotonin transporter gene in young children: the Generation R Study [Texte imprimé et/ou numérique] / Eszter SZEKELY, Auteur ; Catherine M. HERBA, Auteur ; Pascal P. ARP, Auteur ; André G. UITTERLINDEN, Auteur ; Vincent W.V. JADDOE, Auteur ; Albert HOFMAN, Auteur ; Frank C. VERHULST, Auteur ; James J. HUDZIAK, Auteur ; Henning TIEMEIER, Auteur . - 2011 . - p.1279-1286.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 52-12 (December 2011) . - p.1279-1286
Mots-clés : Serotonin transporter gene emotion processing facial expression fear children Index. décimale : PER Périodiques Résumé : Background: Previous research highlights the significance of a functional polymorphism located in the promoter region (5-HTTLPR) of the serotonin transporter gene in emotional behaviour. This study examined the effect of the 5-HTTLPR polymorphism on emotion processing in a large number of healthy preschoolers.
Methods: The 5-HTTLPR genotype was classified in 605 children as homozygous for the short allele (SS), homozygous for the long allele (LL), or heterozygous (LS). Emotion-processing was assessed using age-appropriate computer tasks where children matched happy, sad, angry, and fearful facial expressions preceded by a shape-matching task to assess basic matching ability.
Results: We found that young children could differentiate between emotion categories (F = 12.1, p < .001). The effect of 5-HTTLPR genotype depended on the emotion category presented (F = 2.3, p = .031). This effect was explained by the finding that SS children were less accurate at recognising fearful faces than LL or LS children (F = 5.3, p = .005). We did not find any significant differences as a result of 5-HTTLPR genotype for happy, sad or angry expressions (p > .05).
Conclusions: Results indicate that 5-HTTLPR allele status selectively impacts the processing of fearful but not other facial expressions. This pattern is already apparent in very young typically developing children. Results may signal an early vulnerability for affective problems before disorders emerge.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02423.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=146