Differential Performance of Social Communication Questionnaire Items in African American/Black vs. White Children / Ethan DAHL in Journal of Autism and Developmental Disorders, 54-5 (May 2024)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 54-5 (May 2024) . - p.1820-1833 Titre : Differential Performance of Social Communication Questionnaire Items in African American/Black vs. White Children Type de document : Texte imprimé et/ou numérique Auteurs : Ethan DAHL, Auteur ; Eric J. MOODY, Auteur ; Brian BARGER, Auteur ; Steven ROSENBERG, Auteur ; Carolyn DIGUISEPPI, Auteur ; M. Daniele FALLIN, Auteur ; Li-Ching LEE, Auteur ; Lisa WIGGINS, Auteur Article en page(s) : p.1820-1833 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Screening for autism spectrum disorder (ASD) is an essential early step in the identification process and inaccurate screening may lead to significant delays in the onset of treatment. Past research has highlighted discrepancies in the performance of ASD screening tools such as the Social Communication Questionnaire (SCQ) among certain racial and ethnic groups. The current study explored the functioning of the SCQ among African American/Black and White respondents based on item level performance on the measure. Differential Item Functioning (DIF) analyses showed that 16 (41%) items of the SCQ functioned differently for African American/Black respondents when compared to White respondents. Implications, such as the potential for delayed diagnosis and treatment, and the influence on downstream outcomes, are discussed. En ligne : https://doi.org/10.1007/s10803-023-05931-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=530 [article] Differential Performance of Social Communication Questionnaire Items in African American/Black vs. White Children [Texte imprimé et/ou numérique] / Ethan DAHL, Auteur ; Eric J. MOODY, Auteur ; Brian BARGER, Auteur ; Steven ROSENBERG, Auteur ; Carolyn DIGUISEPPI, Auteur ; M. Daniele FALLIN, Auteur ; Li-Ching LEE, Auteur ; Lisa WIGGINS, Auteur . - p.1820-1833. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 54-5 (May 2024) . - p.1820-1833 Index. décimale : PER Périodiques Résumé : Screening for autism spectrum disorder (ASD) is an essential early step in the identification process and inaccurate screening may lead to significant delays in the onset of treatment. Past research has highlighted discrepancies in the performance of ASD screening tools such as the Social Communication Questionnaire (SCQ) among certain racial and ethnic groups. The current study explored the functioning of the SCQ among African American/Black and White respondents based on item level performance on the measure. Differential Item Functioning (DIF) analyses showed that 16 (41%) items of the SCQ functioned differently for African American/Black respondents when compared to White respondents. Implications, such as the potential for delayed diagnosis and treatment, and the influence on downstream outcomes, are discussed. En ligne : https://doi.org/10.1007/s10803-023-05931-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=530

Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression / Meghan E. Carey in Journal of Autism and Developmental Disorders, 53-8 (August 2023)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 53-8 (August 2023) . - p.2975-2985 Titre : Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression Type de document : Texte imprimé et/ou numérique Auteurs : Meghan E. Carey, Auteur ; Juliette RANDO, Auteur ; Stepan MELNYK, Auteur ; S. Jill JAMES, Auteur ; Nathaniel SNYDER, Auteur ; Carolyn SALAFIA, Auteur ; Lisa A. CROEN, Auteur ; M. Daniele FALLIN, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Heather VOLK, Auteur ; Craig NEWSCHAFFER, Auteur ; Kristen LYALL, Auteur Article en page(s) : p.2975-2985 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : We examined associations between prenatal oxidative stress (OS) and child autism-related outcomes. Women with an autistic child were followed through a subsequent pregnancy and that younger sibling?s childhood. Associations between glutathione (GSH), glutathione disulfide (GSSG), 8-oxo-deoxyguanine (8-OHdG), and nitrotyrosine and younger sibling Social Responsiveness Scale (SRS) scores were examined using quantile regression. Increasing GSH:GSSG (suggesting decreasing OS) was associated with minor increases in SRS scores (50th percentile ?: 1.78, 95% CI: 0.67, 3.06); no other associations were observed. Results from this cohort with increased risk for autism do not support a strong relationship between OS in late pregnancy and autism-related outcomes. Results may be specific to those with enriched autism risk; future work should consider other timepoints and biomarkers. En ligne : https://doi.org/10.1007/s10803-022-05625-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=508 [article] Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression [Texte imprimé et/ou numérique] / Meghan E. Carey, Auteur ; Juliette RANDO, Auteur ; Stepan MELNYK, Auteur ; S. Jill JAMES, Auteur ; Nathaniel SNYDER, Auteur ; Carolyn SALAFIA, Auteur ; Lisa A. CROEN, Auteur ; M. Daniele FALLIN, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Heather VOLK, Auteur ; Craig NEWSCHAFFER, Auteur ; Kristen LYALL, Auteur . - p.2975-2985. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 53-8 (August 2023) . - p.2975-2985 Index. décimale : PER Périodiques Résumé : We examined associations between prenatal oxidative stress (OS) and child autism-related outcomes. Women with an autistic child were followed through a subsequent pregnancy and that younger sibling?s childhood. Associations between glutathione (GSH), glutathione disulfide (GSSG), 8-oxo-deoxyguanine (8-OHdG), and nitrotyrosine and younger sibling Social Responsiveness Scale (SRS) scores were examined using quantile regression. Increasing GSH:GSSG (suggesting decreasing OS) was associated with minor increases in SRS scores (50th percentile ?: 1.78, 95% CI: 0.67, 3.06); no other associations were observed. Results from this cohort with increased risk for autism do not support a strong relationship between OS in late pregnancy and autism-related outcomes. Results may be specific to those with enriched autism risk; future work should consider other timepoints and biomarkers. En ligne : https://doi.org/10.1007/s10803-022-05625-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=508

Exploring a Role for Parental Mental Health in Perception and Reports of Pain on Behalf of Children with Autism Spectrum Disorder / Luke P. GROSVENOR in Autism Research and Treatment, 2021 (2021)  

Public ISBD [article]  inAutism Research and Treatment > 2021 (2021) . - 2981383 Titre : Exploring a Role for Parental Mental Health in Perception and Reports of Pain on Behalf of Children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Luke P. GROSVENOR, Auteur ; Daniel G. WHITNEY, Auteur ; Heather E. VOLK, Auteur ; M. Daniele FALLIN, Auteur Article en page(s) : 2981383 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) have a higher prevalence of pain compared to those without ASD. Pain is a leading cause of morbidity and disability worldwide and may contribute to adverse health outcomes in people with ASD, thus warranting further research on this special population. The present study used data from 1,423 children with ASD and 46,023 children without ASD and their mothers from the combined 2016-2017 National Survey of Children’s Health. Mothers reported child pain and ASD status and their own mental health status. Mothers reporting a status of “Fair or Poor” were considered as having maternal mental health conditions (MMHCs) for the purposes of this study. Children with and without ASD who had mothers with MMHCs had higher odds of pain compared to children with mothers without MMHCs. These increased odds did not attenuate as a result of controlling for co-occurring neurological conditions, which have been associated with increased pain in children with ASD. Thus, parent mental health may alter perception and/or reports of pain on behalf of children with and without ASD. Future research should include more detailed assessments of parent mental health and clinical assessments of children in order to explore the role of parent mental health in the experiences of pain and other symptoms present in children with ASD. En ligne : https://doi.org/10.1155/2021/2981383 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=460 [article] Exploring a Role for Parental Mental Health in Perception and Reports of Pain on Behalf of Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Luke P. GROSVENOR, Auteur ; Daniel G. WHITNEY, Auteur ; Heather E. VOLK, Auteur ; M. Daniele FALLIN, Auteur . - 2981383. Langues : Anglais (eng) in Autism Research and Treatment > 2021 (2021) . - 2981383 Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) have a higher prevalence of pain compared to those without ASD. Pain is a leading cause of morbidity and disability worldwide and may contribute to adverse health outcomes in people with ASD, thus warranting further research on this special population. The present study used data from 1,423 children with ASD and 46,023 children without ASD and their mothers from the combined 2016-2017 National Survey of Children’s Health. Mothers reported child pain and ASD status and their own mental health status. Mothers reporting a status of “Fair or Poor” were considered as having maternal mental health conditions (MMHCs) for the purposes of this study. Children with and without ASD who had mothers with MMHCs had higher odds of pain compared to children with mothers without MMHCs. These increased odds did not attenuate as a result of controlling for co-occurring neurological conditions, which have been associated with increased pain in children with ASD. Thus, parent mental health may alter perception and/or reports of pain on behalf of children with and without ASD. Future research should include more detailed assessments of parent mental health and clinical assessments of children in order to explore the role of parent mental health in the experiences of pain and other symptoms present in children with ASD. En ligne : https://doi.org/10.1155/2021/2981383 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=460

Gastrointestinal symptoms in autism spectrum disorder: A review of the literature on ascertainment and prevalence / Calliope HOLINGUE in Autism Research, 11-1 (January 2018)  

Public ISBD [article]  inAutism Research > 11-1 (January 2018) . - p.24-36 Titre : Gastrointestinal symptoms in autism spectrum disorder: A review of the literature on ascertainment and prevalence Type de document : Texte imprimé et/ou numérique Auteurs : Calliope HOLINGUE, Auteur ; Carol NEWILL, Auteur ; Li-Ching LEE, Auteur ; Pankaj J. PASRICHA, Auteur ; M. Daniele FALLIN, Auteur Article en page(s) : p.24-36 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : There is no standard approach to measuring GI symptoms in individuals with ASD, despite postulated interactions. The objectives of this study were to (a) describe the range of GI symptom ascertainment approaches in studies of ASD, (b) describe the range of prevalence estimates across studies, and (c) assess associations between ascertainment approach and prevalence estimates. Studies published from 1/1/1980 to 1/31/2017 were collected via PubMed. Eligibility included studies with at least ten individuals with ASD that measured GI symptoms or conditions. We excluded review and hypothesis papers. We extracted information on study design, GI symptom ascertainment method, demographics, and ASD diagnostic criteria. From a subset of studies, we extracted GI symptom estimates. Out of a possible 386 titles, 144 were included. The prevalence range for constipation was 4.3–45.5% (median 22%), for diarrhea was 2.3–75.6% (median 13.0%), and for any or more than one symptom was 4.2–96.8% (median 46.8%). GI symptoms differed significantly by age of individuals, primary goal of study, study design, study sample, and who reported symptoms (P? En ligne : https://doi.org/10.1002/aur.1854 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=333 [article] Gastrointestinal symptoms in autism spectrum disorder: A review of the literature on ascertainment and prevalence [Texte imprimé et/ou numérique] / Calliope HOLINGUE, Auteur ; Carol NEWILL, Auteur ; Li-Ching LEE, Auteur ; Pankaj J. PASRICHA, Auteur ; M. Daniele FALLIN, Auteur . - p.24-36. Langues : Anglais (eng) in Autism Research > 11-1 (January 2018) . - p.24-36 Index. décimale : PER Périodiques Résumé : There is no standard approach to measuring GI symptoms in individuals with ASD, despite postulated interactions. The objectives of this study were to (a) describe the range of GI symptom ascertainment approaches in studies of ASD, (b) describe the range of prevalence estimates across studies, and (c) assess associations between ascertainment approach and prevalence estimates. Studies published from 1/1/1980 to 1/31/2017 were collected via PubMed. Eligibility included studies with at least ten individuals with ASD that measured GI symptoms or conditions. We excluded review and hypothesis papers. We extracted information on study design, GI symptom ascertainment method, demographics, and ASD diagnostic criteria. From a subset of studies, we extracted GI symptom estimates. Out of a possible 386 titles, 144 were included. The prevalence range for constipation was 4.3–45.5% (median 22%), for diarrhea was 2.3–75.6% (median 13.0%), and for any or more than one symptom was 4.2–96.8% (median 46.8%). GI symptoms differed significantly by age of individuals, primary goal of study, study design, study sample, and who reported symptoms (P? En ligne : https://doi.org/10.1002/aur.1854 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=333

Gestational thyroid hormones and autism-related traits in the EARLI and HOME studies / Caichen ZHONG in Autism Research, 17-4 (April 2024)  

Public ISBD [article]  inAutism Research > 17-4 (April 2024) . - p.716-727 Titre : Gestational thyroid hormones and autism-related traits in the EARLI and HOME studies Type de document : Texte imprimé et/ou numérique Auteurs : Caichen ZHONG, Auteur ; Juliette RANDO, Auteur ; Marisa A. PATTI, Auteur ; Joseph M. BRAUN, Auteur ; Aimin CHEN, Auteur ; Yingying XU, Auteur ; Bruce P. LANPHEAR, Auteur ; Kimberly YOLTON, Auteur ; Lisa A. CROEN, Auteur ; M. Daniele FALLIN, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Craig J. NEWSCHAFFER, Auteur ; Kristen LYALL, Auteur Article en page(s) : p.716-727 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Thyroid hormones are essential for neurodevelopment. Few studies have considered associations with quantitatively measured autism spectrum disorder (ASD)-related traits, which may help elucidate associations for a broader population. Participants were drawn from two prospective pregnancy cohorts: the Early Autism Risk Longitudinal Investigation (EARLI), enrolling pregnant women who already had a child with ASD, and the Health Outcomes and Measures of the Environment (HOME) Study, following pregnant women from the greater Cincinnati, OH area. Gestational thyroid-stimulating hormone (TSH) and free thyroxine (FT4) were measured in mid-pregnancy 16 (+3) weeks gestation serum samples. ASD-related traits were measured using the Social Responsiveness Scale (SRS) at ages 3-8?years. The association was examined using quantile regression, adjusting for maternal and sociodemographic factors. 278 participants (132 from EARLI, 146 from HOME) were included. TSH distributions were similar across cohorts, while FT4 levels were higher in EARLI compared to HOME. In pooled analyses, particularly for those in the highest SRS quantile (95th percentile), higher FT4 levels were associated with increasing SRS scores (? = 5.21, 95% CI = 0.93, 9.48), and higher TSH levels were associated with decreasing SRS scores (? = ?6.94, 95% CI = ?11.04, ?2.83). The association between TSH and SRS remained significant in HOME for the 95% percentile of SRS scores (? = ?6.48, 95% CI = ?12.16, ?0.80), but not EARLI. Results for FT4 were attenuated when examined in the individual cohorts. Our results add to evidence that gestational thyroid hormones may be associated with ASD-related outcomes by suggesting that relationships may differ across the distribution of ASD-related traits and by familial likelihood of ASD. En ligne : https://doi.org/10.1002/aur.3115 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=526 [article] Gestational thyroid hormones and autism-related traits in the EARLI and HOME studies [Texte imprimé et/ou numérique] / Caichen ZHONG, Auteur ; Juliette RANDO, Auteur ; Marisa A. PATTI, Auteur ; Joseph M. BRAUN, Auteur ; Aimin CHEN, Auteur ; Yingying XU, Auteur ; Bruce P. LANPHEAR, Auteur ; Kimberly YOLTON, Auteur ; Lisa A. CROEN, Auteur ; M. Daniele FALLIN, Auteur ; Irva HERTZ-PICCIOTTO, Auteur ; Craig J. NEWSCHAFFER, Auteur ; Kristen LYALL, Auteur . - p.716-727. Langues : Anglais (eng) in Autism Research > 17-4 (April 2024) . - p.716-727 Index. décimale : PER Périodiques Résumé : Abstract Thyroid hormones are essential for neurodevelopment. Few studies have considered associations with quantitatively measured autism spectrum disorder (ASD)-related traits, which may help elucidate associations for a broader population. Participants were drawn from two prospective pregnancy cohorts: the Early Autism Risk Longitudinal Investigation (EARLI), enrolling pregnant women who already had a child with ASD, and the Health Outcomes and Measures of the Environment (HOME) Study, following pregnant women from the greater Cincinnati, OH area. Gestational thyroid-stimulating hormone (TSH) and free thyroxine (FT4) were measured in mid-pregnancy 16 (+3) weeks gestation serum samples. ASD-related traits were measured using the Social Responsiveness Scale (SRS) at ages 3-8?years. The association was examined using quantile regression, adjusting for maternal and sociodemographic factors. 278 participants (132 from EARLI, 146 from HOME) were included. TSH distributions were similar across cohorts, while FT4 levels were higher in EARLI compared to HOME. In pooled analyses, particularly for those in the highest SRS quantile (95th percentile), higher FT4 levels were associated with increasing SRS scores (? = 5.21, 95% CI = 0.93, 9.48), and higher TSH levels were associated with decreasing SRS scores (? = ?6.94, 95% CI = ?11.04, ?2.83). The association between TSH and SRS remained significant in HOME for the 95% percentile of SRS scores (? = ?6.48, 95% CI = ?12.16, ?0.80), but not EARLI. Results for FT4 were attenuated when examined in the individual cohorts. Our results add to evidence that gestational thyroid hormones may be associated with ASD-related outcomes by suggesting that relationships may differ across the distribution of ASD-related traits and by familial likelihood of ASD. En ligne : https://doi.org/10.1002/aur.3115 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=526

Influence of family demographic factors on social communication questionnaire scores / A. ROSENBERG STEVEN in Autism Research, 11-5 (May 2018)  

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Maternal Exposure to Occupational Asthmagens During Pregnancy and Autism Spectrum Disorder in the Study to Explore Early Development / Alison B. SINGER in Journal of Autism and Developmental Disorders, 46-11 (November 2016)  

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Maternal tobacco smoking and offspring autism spectrum disorder or traits in ECHO cohorts / Irva HERTZ-PICCIOTTO in Autism Research, 15-3 (March 2022)  

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Prenatal exposure to fever is associated with autism spectrum disorder in the boston birth cohort / Martha BRUCATO in Autism Research, 10-11 (November 2017)  

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The Study to Explore Early Development (SEED): A Multisite Epidemiologic Study of Autism by the Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) Network / Diana SCHENDEL in Journal of Autism and Developmental Disorders, 42-10 (October 2012)  

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