Brain Mechanisms for Processing Direct and Averted Gaze in Individuals with Autism / Naomi PITSKEL in Journal of Autism and Developmental Disorders, 41-12 (December 2011)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 41-12 (December 2011) . - p.1686-1693 Titre : Brain Mechanisms for Processing Direct and Averted Gaze in Individuals with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Naomi PITSKEL, Auteur ; Danielle Z. BOLLING, Auteur ; Caitlin M. HUDAC, Auteur ; Stephen LANTZ, Auteur ; Nancy J. MINSHEW, Auteur ; Brent C. VANDER WYK, Auteur ; Kevin A. PELPHREY, Auteur Année de publication : 2011 Article en page(s) : p.1686-1693 Langues : Anglais (eng) Mots-clés : Autism  Direct gaze  Averted gaze  Gaze processing  Functional magnetic resonance imaging Index. décimale : PER Périodiques Résumé : Prior studies have indicated brain abnormalities underlying social processing in autism, but no fMRI study has specifically addressed the differential processing of direct and averted gaze, a critical social cue. Fifteen adolescents and adults with autism and 14 typically developing comparison participants viewed dynamic virtual-reality videos depicting a simple but realistic social scenario, in which an approaching male figure maintained either direct or averted gaze. Significant group by condition interactions reflecting differential responses to direct versus averted gaze in people with autism relative to typically developing individuals were identified in the right temporoparietal junction, right anterior insula, left lateral occipital cortex, and left dorsolateral prefrontal cortex. Our results provide initial evidence regarding brain mechanisms underlying the processing of gaze direction during simple social encounters, providing new insight into the social deficits in individuals with autism. En ligne : http://dx.doi.org/10.1007/s10803-011-1197-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=148 [article] Brain Mechanisms for Processing Direct and Averted Gaze in Individuals with Autism [Texte imprimé et/ou numérique] / Naomi PITSKEL, Auteur ; Danielle Z. BOLLING, Auteur ; Caitlin M. HUDAC, Auteur ; Stephen LANTZ, Auteur ; Nancy J. MINSHEW, Auteur ; Brent C. VANDER WYK, Auteur ; Kevin A. PELPHREY, Auteur . - 2011 . - p.1686-1693. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 41-12 (December 2011) . - p.1686-1693 Mots-clés : Autism  Direct gaze  Averted gaze  Gaze processing  Functional magnetic resonance imaging Index. décimale : PER Périodiques Résumé : Prior studies have indicated brain abnormalities underlying social processing in autism, but no fMRI study has specifically addressed the differential processing of direct and averted gaze, a critical social cue. Fifteen adolescents and adults with autism and 14 typically developing comparison participants viewed dynamic virtual-reality videos depicting a simple but realistic social scenario, in which an approaching male figure maintained either direct or averted gaze. Significant group by condition interactions reflecting differential responses to direct versus averted gaze in people with autism relative to typically developing individuals were identified in the right temporoparietal junction, right anterior insula, left lateral occipital cortex, and left dorsolateral prefrontal cortex. Our results provide initial evidence regarding brain mechanisms underlying the processing of gaze direction during simple social encounters, providing new insight into the social deficits in individuals with autism. En ligne : http://dx.doi.org/10.1007/s10803-011-1197-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=148

Neural Mechanisms of Improvements in Social Motivation After Pivotal Response Treatment: Two Case Studies / Avery C. VOOS in Journal of Autism and Developmental Disorders, 43-1 (January 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-1 (January 2013) . - p.1-10 Titre : Neural Mechanisms of Improvements in Social Motivation After Pivotal Response Treatment: Two Case Studies Type de document : Texte imprimé et/ou numérique Auteurs : Avery C. VOOS, Auteur ; Kevin A. PELPHREY, Auteur ; Jonathan TIRRELL, Auteur ; Danielle Z. BOLLING, Auteur ; Brent C. VANDER WYK, Auteur ; Martha D. KAISER, Auteur ; James C. MCPARTLAND, Auteur ; Fred R. VOLKMAR, Auteur ; Pamela VENTOLA, Auteur Article en page(s) : p.1-10 Langues : Anglais (eng) Mots-clés : Pivotal response treatment  fMRI  Autism  Intervention  Outcome Index. décimale : PER Périodiques Résumé : Pivotal response treatment (PRT) is an empirically validated behavioral treatment that has widespread positive effects on communication, behavior, and social skills in young children with autism spectrum disorder (ASD). For the first time, functional magnetic resonance imaging was used to identify the neural correlates of successful response to PRT in two young children with ASD. Baseline measures of social communication, adaptive behavior, eye tracking and neural response to social stimuli were taken prior to treatment and after 4 months of PRT. Both children showed striking gains on behavioral measures and also showed increased activation to social stimuli in brain regions utilized by typically developing children. These results suggest that neural systems supporting social perception are malleable through implementation of PRT. En ligne : http://dx.doi.org/10.1007/s10803-012-1683-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=187 [article] Neural Mechanisms of Improvements in Social Motivation After Pivotal Response Treatment: Two Case Studies [Texte imprimé et/ou numérique] / Avery C. VOOS, Auteur ; Kevin A. PELPHREY, Auteur ; Jonathan TIRRELL, Auteur ; Danielle Z. BOLLING, Auteur ; Brent C. VANDER WYK, Auteur ; Martha D. KAISER, Auteur ; James C. MCPARTLAND, Auteur ; Fred R. VOLKMAR, Auteur ; Pamela VENTOLA, Auteur . - p.1-10. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-1 (January 2013) . - p.1-10 Mots-clés : Pivotal response treatment  fMRI  Autism  Intervention  Outcome Index. décimale : PER Périodiques Résumé : Pivotal response treatment (PRT) is an empirically validated behavioral treatment that has widespread positive effects on communication, behavior, and social skills in young children with autism spectrum disorder (ASD). For the first time, functional magnetic resonance imaging was used to identify the neural correlates of successful response to PRT in two young children with ASD. Baseline measures of social communication, adaptive behavior, eye tracking and neural response to social stimuli were taken prior to treatment and after 4 months of PRT. Both children showed striking gains on behavioral measures and also showed increased activation to social stimuli in brain regions utilized by typically developing children. These results suggest that neural systems supporting social perception are malleable through implementation of PRT. En ligne : http://dx.doi.org/10.1007/s10803-012-1683-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=187

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