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Affective–motivational brain responses to direct gaze in children with autism spectrum disorder / Anneli KYLLIAINEN in Journal of Child Psychology and Psychiatry, 53-7 (July 2012)
[article]
Titre : Affective–motivational brain responses to direct gaze in children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Anneli KYLLIAINEN, Auteur ; Simon WALLACE, Auteur ; Marc N. COUTANCHE, Auteur ; Jukka M. LEPPANEN, Auteur ; James CUSACK, Auteur ; Anthony J. BAILEY, Auteur ; Jari K. HIETANEN, Auteur Année de publication : 2012 Article en page(s) : p.790-797 Langues : Anglais (eng) Mots-clés : Direct gaze eye contact autism spectrum disorders frontal EEG asymmetry skin conductance Index. décimale : PER Périodiques Résumé : Background: It is unclear why children with autism spectrum disorders (ASD) tend to be inattentive to, or even avoid eye contact. The goal of this study was to investigate affective–motivational brain responses to direct gaze in children with ASD. To this end, we combined two measurements: skin conductance responses (SCR), a robust arousal measure, and asymmetry in frontal electroencephalography (EEG) activity which is associated with motivational approach and avoidance tendencies. We also explored whether degree of eye openness and face familiarity modulated these responses.
Methods: Skin conductance responses and frontal EEG activity were recorded from 14 children with ASD and 15 typically developing children whilst they looked at familiar and unfamiliar faces with eyes shut, normally open or wide-open. Stimuli were presented in such a way that they appeared to be looming towards the children.
Results: In typically developing children, there were no significant differences in SCRs between the different eye conditions, whereas in the ASD group the SCRs were attenuated to faces with closed eyes and increased as a function of the degree of eye openness. In both groups, familiar faces elicited marginally greater SCRs than unfamiliar faces. In typically developing children, normally open eyes elicited greater relative left-sided frontal EEG activity (associated with motivational approach) than shut eyes and wide-open eyes. In the ASD group, there were no significant differences between the gaze conditions in frontal EEG activity.
Conclusions: Collectively, the results replicate previous finding in showing atypical modulation of arousal in response to direct gaze in children with ASD but do not support the assumption that this response is associated with an avoidant motivational tendency. Instead, children with ASD may lack normative approach-related motivational response to eye contact.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02522.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166
in Journal of Child Psychology and Psychiatry > 53-7 (July 2012) . - p.790-797[article] Affective–motivational brain responses to direct gaze in children with autism spectrum disorder [Texte imprimé et/ou numérique] / Anneli KYLLIAINEN, Auteur ; Simon WALLACE, Auteur ; Marc N. COUTANCHE, Auteur ; Jukka M. LEPPANEN, Auteur ; James CUSACK, Auteur ; Anthony J. BAILEY, Auteur ; Jari K. HIETANEN, Auteur . - 2012 . - p.790-797.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 53-7 (July 2012) . - p.790-797
Mots-clés : Direct gaze eye contact autism spectrum disorders frontal EEG asymmetry skin conductance Index. décimale : PER Périodiques Résumé : Background: It is unclear why children with autism spectrum disorders (ASD) tend to be inattentive to, or even avoid eye contact. The goal of this study was to investigate affective–motivational brain responses to direct gaze in children with ASD. To this end, we combined two measurements: skin conductance responses (SCR), a robust arousal measure, and asymmetry in frontal electroencephalography (EEG) activity which is associated with motivational approach and avoidance tendencies. We also explored whether degree of eye openness and face familiarity modulated these responses.
Methods: Skin conductance responses and frontal EEG activity were recorded from 14 children with ASD and 15 typically developing children whilst they looked at familiar and unfamiliar faces with eyes shut, normally open or wide-open. Stimuli were presented in such a way that they appeared to be looming towards the children.
Results: In typically developing children, there were no significant differences in SCRs between the different eye conditions, whereas in the ASD group the SCRs were attenuated to faces with closed eyes and increased as a function of the degree of eye openness. In both groups, familiar faces elicited marginally greater SCRs than unfamiliar faces. In typically developing children, normally open eyes elicited greater relative left-sided frontal EEG activity (associated with motivational approach) than shut eyes and wide-open eyes. In the ASD group, there were no significant differences between the gaze conditions in frontal EEG activity.
Conclusions: Collectively, the results replicate previous finding in showing atypical modulation of arousal in response to direct gaze in children with ASD but do not support the assumption that this response is associated with an avoidant motivational tendency. Instead, children with ASD may lack normative approach-related motivational response to eye contact.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02522.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166 Attentional biases to faces with direct versus averted gaze in children without and with autism spectrum disorder: A dot-probe paradigm / Wei JING in Research in Autism Spectrum Disorders, 108 (October 2023)
[article]
Titre : Attentional biases to faces with direct versus averted gaze in children without and with autism spectrum disorder: A dot-probe paradigm Type de document : Texte imprimé et/ou numérique Auteurs : Wei JING, Auteur ; Jing WANG, Auteur ; Jinxia FU, Auteur Article en page(s) : p.102233 Mots-clés : Children with ASD Dot-probe paradigms Direct gaze Averted gaze Facial attention Index. décimale : PER Périodiques Résumé : Previous research utilized a variety of paradigms to demonstrate attentional biases to faces with direct versus averted gaze in typical development (TD) and no such bias in autism spectrum disorder (ASD). However, little is known about whether the biases can be observed during automatic processing stages in TD and whether the lack of such bias in ASD is due to passive neglect or active avoidance of direct gaze. Therefore, we employed a dot-probe paradigm and manipulated stimulus onset asynchrony (SOA) to measure response times to probes replacing faces with direct gaze compared to faces with averted gaze in children without and with ASD. There was no evidence of attentional bias in either group when stimuli were presented during the automatic processing stage (200 ms SOA). However, during the controlled processing stage (1000 ms SOA), an attentional bias to faces with direct versus averted gaze was found in control children but not in those with ASD. The results indicate that the facilitation of direct gaze on facial attention occurs during controlled rather than automatic processing stages in TD individuals. In contrast, children with ASD respond indiscriminately to direct and averted gaze during both stages of cognitive processing, supporting the gaze indifference hypothesis. For TD children but not for children with ASD, direct gaze is an adaptively informative or socially salient signal. En ligne : https://doi.org/10.1016/j.rasd.2023.102233 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=514
in Research in Autism Spectrum Disorders > 108 (October 2023) . - p.102233[article] Attentional biases to faces with direct versus averted gaze in children without and with autism spectrum disorder: A dot-probe paradigm [Texte imprimé et/ou numérique] / Wei JING, Auteur ; Jing WANG, Auteur ; Jinxia FU, Auteur . - p.102233.
in Research in Autism Spectrum Disorders > 108 (October 2023) . - p.102233
Mots-clés : Children with ASD Dot-probe paradigms Direct gaze Averted gaze Facial attention Index. décimale : PER Périodiques Résumé : Previous research utilized a variety of paradigms to demonstrate attentional biases to faces with direct versus averted gaze in typical development (TD) and no such bias in autism spectrum disorder (ASD). However, little is known about whether the biases can be observed during automatic processing stages in TD and whether the lack of such bias in ASD is due to passive neglect or active avoidance of direct gaze. Therefore, we employed a dot-probe paradigm and manipulated stimulus onset asynchrony (SOA) to measure response times to probes replacing faces with direct gaze compared to faces with averted gaze in children without and with ASD. There was no evidence of attentional bias in either group when stimuli were presented during the automatic processing stage (200 ms SOA). However, during the controlled processing stage (1000 ms SOA), an attentional bias to faces with direct versus averted gaze was found in control children but not in those with ASD. The results indicate that the facilitation of direct gaze on facial attention occurs during controlled rather than automatic processing stages in TD individuals. In contrast, children with ASD respond indiscriminately to direct and averted gaze during both stages of cognitive processing, supporting the gaze indifference hypothesis. For TD children but not for children with ASD, direct gaze is an adaptively informative or socially salient signal. En ligne : https://doi.org/10.1016/j.rasd.2023.102233 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=514 Brain Mechanisms for Processing Direct and Averted Gaze in Individuals with Autism / Naomi PITSKEL in Journal of Autism and Developmental Disorders, 41-12 (December 2011)
[article]
Titre : Brain Mechanisms for Processing Direct and Averted Gaze in Individuals with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Naomi PITSKEL, Auteur ; Danielle Z. BOLLING, Auteur ; Caitlin M. HUDAC, Auteur ; Stephen LANTZ, Auteur ; Nancy J. MINSHEW, Auteur ; Brent C. VANDER WYK, Auteur ; Kevin A. PELPHREY, Auteur Année de publication : 2011 Article en page(s) : p.1686-1693 Langues : Anglais (eng) Mots-clés : Autism Direct gaze Averted gaze Gaze processing Functional magnetic resonance imaging Index. décimale : PER Périodiques Résumé : Prior studies have indicated brain abnormalities underlying social processing in autism, but no fMRI study has specifically addressed the differential processing of direct and averted gaze, a critical social cue. Fifteen adolescents and adults with autism and 14 typically developing comparison participants viewed dynamic virtual-reality videos depicting a simple but realistic social scenario, in which an approaching male figure maintained either direct or averted gaze. Significant group by condition interactions reflecting differential responses to direct versus averted gaze in people with autism relative to typically developing individuals were identified in the right temporoparietal junction, right anterior insula, left lateral occipital cortex, and left dorsolateral prefrontal cortex. Our results provide initial evidence regarding brain mechanisms underlying the processing of gaze direction during simple social encounters, providing new insight into the social deficits in individuals with autism. En ligne : http://dx.doi.org/10.1007/s10803-011-1197-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=148
in Journal of Autism and Developmental Disorders > 41-12 (December 2011) . - p.1686-1693[article] Brain Mechanisms for Processing Direct and Averted Gaze in Individuals with Autism [Texte imprimé et/ou numérique] / Naomi PITSKEL, Auteur ; Danielle Z. BOLLING, Auteur ; Caitlin M. HUDAC, Auteur ; Stephen LANTZ, Auteur ; Nancy J. MINSHEW, Auteur ; Brent C. VANDER WYK, Auteur ; Kevin A. PELPHREY, Auteur . - 2011 . - p.1686-1693.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 41-12 (December 2011) . - p.1686-1693
Mots-clés : Autism Direct gaze Averted gaze Gaze processing Functional magnetic resonance imaging Index. décimale : PER Périodiques Résumé : Prior studies have indicated brain abnormalities underlying social processing in autism, but no fMRI study has specifically addressed the differential processing of direct and averted gaze, a critical social cue. Fifteen adolescents and adults with autism and 14 typically developing comparison participants viewed dynamic virtual-reality videos depicting a simple but realistic social scenario, in which an approaching male figure maintained either direct or averted gaze. Significant group by condition interactions reflecting differential responses to direct versus averted gaze in people with autism relative to typically developing individuals were identified in the right temporoparietal junction, right anterior insula, left lateral occipital cortex, and left dorsolateral prefrontal cortex. Our results provide initial evidence regarding brain mechanisms underlying the processing of gaze direction during simple social encounters, providing new insight into the social deficits in individuals with autism. En ligne : http://dx.doi.org/10.1007/s10803-011-1197-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=148 Brief Report: Broader Autism Phenotype Predicts Spontaneous Reciprocity of Direct Gaze / Frances S. CHEN in Journal of Autism and Developmental Disorders, 41-8 (August 2011)
[article]
Titre : Brief Report: Broader Autism Phenotype Predicts Spontaneous Reciprocity of Direct Gaze Type de document : Texte imprimé et/ou numérique Auteurs : Frances S. CHEN, Auteur ; Jennifer M. D. YOON, Auteur Année de publication : 2011 Article en page(s) : p.1131-1134 Langues : Anglais (eng) Mots-clés : Eye contact Direct gaze Broader autism phenotype Autism-Spectrum Quotient Index. décimale : PER Périodiques Résumé : We report evidence for a relationship in the general population between self-reported autism-associated traits and the spontaneous reciprocation of direct gaze, a behavior that we propose may reflect a tendency to synchronize with social partners. Adults viewed videos of actors whose gaze was either directed towards or averted from them. Individuals with lower scores on four subscales of the Autism-Spectrum Quotient (AQ) scale showed a greater tendency to look at directed relative to averted eyes; individuals with higher scores on the AQ did not. This relationship was specific to autism-associated traits and to gaze towards the eyes; it did not generalize to a social anxiety measure or to gaze towards the mouth. We discuss implications for our understanding of the broader autism phenotype. En ligne : http://dx.doi.org/10.1007/s10803-010-1136-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=132
in Journal of Autism and Developmental Disorders > 41-8 (August 2011) . - p.1131-1134[article] Brief Report: Broader Autism Phenotype Predicts Spontaneous Reciprocity of Direct Gaze [Texte imprimé et/ou numérique] / Frances S. CHEN, Auteur ; Jennifer M. D. YOON, Auteur . - 2011 . - p.1131-1134.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 41-8 (August 2011) . - p.1131-1134
Mots-clés : Eye contact Direct gaze Broader autism phenotype Autism-Spectrum Quotient Index. décimale : PER Périodiques Résumé : We report evidence for a relationship in the general population between self-reported autism-associated traits and the spontaneous reciprocation of direct gaze, a behavior that we propose may reflect a tendency to synchronize with social partners. Adults viewed videos of actors whose gaze was either directed towards or averted from them. Individuals with lower scores on four subscales of the Autism-Spectrum Quotient (AQ) scale showed a greater tendency to look at directed relative to averted eyes; individuals with higher scores on the AQ did not. This relationship was specific to autism-associated traits and to gaze towards the eyes; it did not generalize to a social anxiety measure or to gaze towards the mouth. We discuss implications for our understanding of the broader autism phenotype. En ligne : http://dx.doi.org/10.1007/s10803-010-1136-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=132 Infant responses to direct gaze and associations to autism: A live eye-tracking study / Pär NYSTRÖM ; Giorgia BUSSU ; Sven BÖLTE ; Terje FALCK-YTTER in Autism, 28-7 (July 2024)
[article]
Titre : Infant responses to direct gaze and associations to autism: A live eye-tracking study Type de document : Texte imprimé et/ou numérique Auteurs : Pär NYSTRÖM, Auteur ; Giorgia BUSSU, Auteur ; Sven BÖLTE, Auteur ; Terje FALCK-YTTER, Auteur Article en page(s) : p.1677-1689 Langues : Anglais (eng) Mots-clés : autism spectrum disorder direct gaze infant development live eye tracking Index. décimale : PER Périodiques Résumé : Being looked at is an important communicative signal, and attenuated responses to such direct gaze have been suggested as an early sign of autism. Using live eye tracking, we examined whether direct gaze elicits different gaze responses in infants at ages 10, 14 and 18?months with and without later autism in real-life interaction. The sample consisted of 169 infants: 35 with elevated likelihood of autism and subsequent diagnosis, 94 without subsequent diagnosis and 40 with typical likelihood of autism. Infants in all groups tended to look more towards the adult?s face shortly after the direct gaze occurred. Neither how much nor how quickly the infants responded to the direct gaze differentiated the without elevated likelihood of autism and subsequent diagnosis and with elevated likelihood of autism and subsequent diagnosis groups. Infants in the typical likelihood group looked more at the face after the direct-gaze event than infants in the two elevated likelihood groups, but this result is tentative. In an exploratory analysis, infants in the elevated likelihood of autism and subsequent diagnosis group looked away quicker from faces with direct gaze than infants in the typical likelihood group, but this measure did not correlate with dimensional autism or differentiate between the two elevated likelihood groups. The current results suggest that attenuated behavioural responses to direct gaze in infancy are neither strong nor specific early markers of autism. Lay abstract When other people look directly towards us, we often respond by looking back at them, and such direct-gaze responses are important for establishing eye contact. Atypical eye contact is common in autism, but how and when this aspect of autism develops is not well understood. Here, we studied whether how much and how quickly infants respond to others' direct gaze is associated with autism in toddlerhood. We did this by measuring direct-gaze responses in a playful social interaction using live eye tracking. The study included 169 infants, of whom 129 had an elevated likelihood of developing autism due to having a first-degree family member with the condition, and 40 with typical likelihood of autism. In the elevated likelihood group, 35 were diagnosed with autism spectrum disorder at 3?years of age, and 94 were not. The results showed that infants in all three groups tended to increase their looking towards the adult?s face after the adult looked directly at them. However, neither how much nor how quickly the infants responded to direct gaze by looking back at the adult reliably differentiated the infants with or without subsequent autism. While infants in the elevated likelihood of autism and subsequent diagnosis group tended to look away quicker from faces with direct gaze than infants in the typical likelihood group, this measure did not differentiate between the two elevated likelihood groups. We interpret the results as supporting the view that atypical direct-gaze responses are not early markers of autism. En ligne : https://dx.doi.org/10.1177/13623613231203037 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=531
in Autism > 28-7 (July 2024) . - p.1677-1689[article] Infant responses to direct gaze and associations to autism: A live eye-tracking study [Texte imprimé et/ou numérique] / Pär NYSTRÖM, Auteur ; Giorgia BUSSU, Auteur ; Sven BÖLTE, Auteur ; Terje FALCK-YTTER, Auteur . - p.1677-1689.
Langues : Anglais (eng)
in Autism > 28-7 (July 2024) . - p.1677-1689
Mots-clés : autism spectrum disorder direct gaze infant development live eye tracking Index. décimale : PER Périodiques Résumé : Being looked at is an important communicative signal, and attenuated responses to such direct gaze have been suggested as an early sign of autism. Using live eye tracking, we examined whether direct gaze elicits different gaze responses in infants at ages 10, 14 and 18?months with and without later autism in real-life interaction. The sample consisted of 169 infants: 35 with elevated likelihood of autism and subsequent diagnosis, 94 without subsequent diagnosis and 40 with typical likelihood of autism. Infants in all groups tended to look more towards the adult?s face shortly after the direct gaze occurred. Neither how much nor how quickly the infants responded to the direct gaze differentiated the without elevated likelihood of autism and subsequent diagnosis and with elevated likelihood of autism and subsequent diagnosis groups. Infants in the typical likelihood group looked more at the face after the direct-gaze event than infants in the two elevated likelihood groups, but this result is tentative. In an exploratory analysis, infants in the elevated likelihood of autism and subsequent diagnosis group looked away quicker from faces with direct gaze than infants in the typical likelihood group, but this measure did not correlate with dimensional autism or differentiate between the two elevated likelihood groups. The current results suggest that attenuated behavioural responses to direct gaze in infancy are neither strong nor specific early markers of autism. Lay abstract When other people look directly towards us, we often respond by looking back at them, and such direct-gaze responses are important for establishing eye contact. Atypical eye contact is common in autism, but how and when this aspect of autism develops is not well understood. Here, we studied whether how much and how quickly infants respond to others' direct gaze is associated with autism in toddlerhood. We did this by measuring direct-gaze responses in a playful social interaction using live eye tracking. The study included 169 infants, of whom 129 had an elevated likelihood of developing autism due to having a first-degree family member with the condition, and 40 with typical likelihood of autism. In the elevated likelihood group, 35 were diagnosed with autism spectrum disorder at 3?years of age, and 94 were not. The results showed that infants in all three groups tended to increase their looking towards the adult?s face after the adult looked directly at them. However, neither how much nor how quickly the infants responded to direct gaze by looking back at the adult reliably differentiated the infants with or without subsequent autism. While infants in the elevated likelihood of autism and subsequent diagnosis group tended to look away quicker from faces with direct gaze than infants in the typical likelihood group, this measure did not differentiate between the two elevated likelihood groups. We interpret the results as supporting the view that atypical direct-gaze responses are not early markers of autism. En ligne : https://dx.doi.org/10.1177/13623613231203037 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=531 Altered sensitivity to social gaze in the FMR1 premutation and pragmatic language competence / J. KLUSEK in Journal of Neurodevelopmental Disorders, 9-1 (December 2017)
PermalinkGetting a Grip on Social Gaze: Control over Others? Gaze Helps Gaze Detection in High-Functioning Autism / Thomas DRATSCH in Journal of Autism and Developmental Disorders, 43-2 (February 2013)
PermalinkPropensity to Imitate in Autism Is Not Modulated by the Model's Gaze Direction: An Eye-Tracking Study / Giacomo VIVANTI in Autism Research, 7-3 (June 2014)
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