Alpha modulation during working memory encoding predicts neurocognitive impairment in ADHD / Agatha LENARTOWICZ in Journal of Child Psychology and Psychiatry, 60-8 (August 2019)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 60-8 (August 2019) . - p.917-926 Titre : Alpha modulation during working memory encoding predicts neurocognitive impairment in ADHD Type de document : texte imprimé Auteurs : Agatha LENARTOWICZ, Auteur ; Holly TRUONG, Auteur ; Giulia C. SALGARI, Auteur ; Robert M. BILDER, Auteur ; James MCGOUGH, Auteur ; James T. MCCRACKEN, Auteur ; Sandra K. LOO, Auteur Article en page(s) : p.917-926 Langues : Anglais (eng) Mots-clés : Adhd  Eeg  academic achievement  alpha oscillations  maintenance  visual attention  working memory Index. décimale : PER Périodiques Résumé : BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is associated with working memory (WM) deficits. However, WM is a multiprocess construct that can be impaired through several pathways, leaving the source of WM impairments in ADHD unresolved. In this study, we aim to replicate, in an independent sample, previously reported deficits in component processes of WM deficits in ADHD and expand to consider their implications for neurocognitive outcomes. METHODS: In 119 children (7-14 years old, 85 with ADHD), we used electroencephalography measures to quantify component processes during performance of a spatial working memory task. We quantified stimulus encoding using alpha range (8-12 Hz) power; vigilance by the P2 event-related potential to cues; and WMmaintenance by occipital-alpha and frontal-theta (4-7 Hz) power. These measures were evaluated against metrics of executive function, ADHD symptoms, and academic achievement. RESULTS: Encoding alpha-power decreases and cue P2 amplitude were attenuated in ADHD, whereas occipital-alpha power during maintenance was significantly greater in ADHD, consistent with a compensatory response to weak encoding. Weak alpha modulation during encoding was associated with poorer reading comprehension and executive function, as well as enhanced ADHD symptoms. Previously reported effects in frontal-theta power failed to replicate. CONCLUSIONS: Stimulus encoding, a component process of WM coupled to alpha modulation, is impaired in ADHD, and, unlike WM maintenance or vigilance processes, has implications outside of the laboratory via a relationship with executive function, and, to a weaker extent, reading comprehension. En ligne : http://dx.doi.org/10.1111/jcpp.13042 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=404 [article] Alpha modulation during working memory encoding predicts neurocognitive impairment in ADHD [texte imprimé] / Agatha LENARTOWICZ, Auteur ; Holly TRUONG, Auteur ; Giulia C. SALGARI, Auteur ; Robert M. BILDER, Auteur ; James MCGOUGH, Auteur ; James T. MCCRACKEN, Auteur ; Sandra K. LOO, Auteur . - p.917-926. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 60-8 (August 2019) . - p.917-926 Mots-clés : Adhd  Eeg  academic achievement  alpha oscillations  maintenance  visual attention  working memory Index. décimale : PER Périodiques Résumé : BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is associated with working memory (WM) deficits. However, WM is a multiprocess construct that can be impaired through several pathways, leaving the source of WM impairments in ADHD unresolved. In this study, we aim to replicate, in an independent sample, previously reported deficits in component processes of WM deficits in ADHD and expand to consider their implications for neurocognitive outcomes. METHODS: In 119 children (7-14 years old, 85 with ADHD), we used electroencephalography measures to quantify component processes during performance of a spatial working memory task. We quantified stimulus encoding using alpha range (8-12 Hz) power; vigilance by the P2 event-related potential to cues; and WMmaintenance by occipital-alpha and frontal-theta (4-7 Hz) power. These measures were evaluated against metrics of executive function, ADHD symptoms, and academic achievement. RESULTS: Encoding alpha-power decreases and cue P2 amplitude were attenuated in ADHD, whereas occipital-alpha power during maintenance was significantly greater in ADHD, consistent with a compensatory response to weak encoding. Weak alpha modulation during encoding was associated with poorer reading comprehension and executive function, as well as enhanced ADHD symptoms. Previously reported effects in frontal-theta power failed to replicate. CONCLUSIONS: Stimulus encoding, a component process of WM coupled to alpha modulation, is impaired in ADHD, and, unlike WM maintenance or vigilance processes, has implications outside of the laboratory via a relationship with executive function, and, to a weaker extent, reading comprehension. En ligne : http://dx.doi.org/10.1111/jcpp.13042 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=404

Beware of Over-Interpreting Negative Trials / Lawrence SCAHILL in Journal of Autism and Developmental Disorders, 38-9 (October 2008)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 38-9 (October 2008) . - p.1609-1610 Titre : Beware of Over-Interpreting Negative Trials Type de document : texte imprimé Auteurs : Lawrence SCAHILL, Auteur ; Benedetto VITIELLO, Auteur ; Michael G. AMAN, Auteur ; Christopher J. MCDOUGLE, Auteur ; James T. MCCRACKEN, Auteur Année de publication : 2008 Article en page(s) : p.1609-1610 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-008-0581-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=604 [article] Beware of Over-Interpreting Negative Trials [texte imprimé] / Lawrence SCAHILL, Auteur ; Benedetto VITIELLO, Auteur ; Michael G. AMAN, Auteur ; Christopher J. MCDOUGLE, Auteur ; James T. MCCRACKEN, Auteur . - 2008 . - p.1609-1610. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 38-9 (October 2008) . - p.1609-1610 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-008-0581-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=604

Brief Report: Social Disability in Autism Spectrum Disorder: Results from Research Units on Pediatric Psychopharmacology (RUPP) Autism Network Trials / Lawrence SCAHILL in Journal of Autism and Developmental Disorders, 43-3 (March 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-3 (March 2013) . - p.739-746 Titre : Brief Report: Social Disability in Autism Spectrum Disorder: Results from Research Units on Pediatric Psychopharmacology (RUPP) Autism Network Trials Type de document : texte imprimé Auteurs : Lawrence SCAHILL, Auteur ; Victoria HALLETT, Auteur ; Michael G. AMAN, Auteur ; Christopher J. MCDOUGLE, Auteur ; L. Eugene ARNOLD, Auteur ; James T. MCCRACKEN, Auteur ; Elaine TIERNEY, Auteur ; Yanhong DENG, Auteur ; James DZIURA, Auteur ; Benedetto VITIELLO, Auteur Article en page(s) : p.739-746 Langues : Anglais (eng) Mots-clés : Social disability  Autism  Research Units on Pediatric Psychopharmacology (RUPP)  Autism Network  Social withdrawal  Risperidone  Aberrant Behavior Checklist Index. décimale : PER Périodiques Résumé : There is growing interest in measuring social disability as a core element of autism spectrum disorders in medication trials. We conducted a secondary analysis on the Aberrant Behavior Checklist Social Withdrawal subscale using data from two federally-funded, multi-site, randomized trials with risperidone. Study 1 included 52 subjects assigned to placebo and 49 subjects to risperidone under double-blind conditions. Study 2 included 49 subjects assigned to risperidone only and 75 subjects assigned to risperidone plus parent training. After 8 weeks of treatment, all active treatments were superior to placebo (effect sizes ranging from 0.42 to 0.65). The findings suggest that the Social Withdrawal subscale may be a useful measure of social disability in acute treatment trials. En ligne : http://dx.doi.org/10.1007/s10803-012-1689-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=192 [article] Brief Report: Social Disability in Autism Spectrum Disorder: Results from Research Units on Pediatric Psychopharmacology (RUPP) Autism Network Trials [texte imprimé] / Lawrence SCAHILL, Auteur ; Victoria HALLETT, Auteur ; Michael G. AMAN, Auteur ; Christopher J. MCDOUGLE, Auteur ; L. Eugene ARNOLD, Auteur ; James T. MCCRACKEN, Auteur ; Elaine TIERNEY, Auteur ; Yanhong DENG, Auteur ; James DZIURA, Auteur ; Benedetto VITIELLO, Auteur . - p.739-746. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-3 (March 2013) . - p.739-746 Mots-clés : Social disability  Autism  Research Units on Pediatric Psychopharmacology (RUPP)  Autism Network  Social withdrawal  Risperidone  Aberrant Behavior Checklist Index. décimale : PER Périodiques Résumé : There is growing interest in measuring social disability as a core element of autism spectrum disorders in medication trials. We conducted a secondary analysis on the Aberrant Behavior Checklist Social Withdrawal subscale using data from two federally-funded, multi-site, randomized trials with risperidone. Study 1 included 52 subjects assigned to placebo and 49 subjects to risperidone under double-blind conditions. Study 2 included 49 subjects assigned to risperidone only and 75 subjects assigned to risperidone plus parent training. After 8 weeks of treatment, all active treatments were superior to placebo (effect sizes ranging from 0.42 to 0.65). The findings suggest that the Social Withdrawal subscale may be a useful measure of social disability in acute treatment trials. En ligne : http://dx.doi.org/10.1007/s10803-012-1689-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=192

Clinical and Cognitive Correlates of Depressive Symptoms Among Youth with Obsessive Compulsive Disorder / Tara S. PERIS in Journal of Clinical Child & Adolescent Psychology, 39-5 (September-October 2010)  

Public ISBD [article]  inJournal of Clinical Child & Adolescent Psychology > 39-5 (September-October 2010) . - p.616-626 Titre : Clinical and Cognitive Correlates of Depressive Symptoms Among Youth with Obsessive Compulsive Disorder Type de document : texte imprimé Auteurs : Tara S. PERIS, Auteur ; Joan R. ASARNOW, Auteur ; John PIACENTINI, Auteur ; R. Lindsey BERGMAN, Auteur ; Audra K. LANGLEY, Auteur ; James T. MCCRACKEN, Auteur Année de publication : 2010 Article en page(s) : p.616-626 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Depression is the most common comorbidity among adults with obsessive compulsive disorder (OCD), yet little is known about depressive symptoms in childhood OCD. This study examined clinical and cognitive variables associated with depressive symptomatology in 71 youths (62% male, M age = 12.7 years) with primary OCD. Youths presented with a range of depressive symptoms, with 21% scoring at or above the clinical cutoff on the self-report measure of depression. Higher levels of depressive symptoms were associated with higher levels of cognitive distortions assessed on measures of insight, perceived control, competence, and contingencies. Depressive symptoms were also linked to older age and more severe OCD. Low perceived control and self-competence and high OCD severity independently predicted depression scores. En ligne : http://dx.doi.org/10.1080/15374416.2010.501285 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=108 [article] Clinical and Cognitive Correlates of Depressive Symptoms Among Youth with Obsessive Compulsive Disorder [texte imprimé] / Tara S. PERIS, Auteur ; Joan R. ASARNOW, Auteur ; John PIACENTINI, Auteur ; R. Lindsey BERGMAN, Auteur ; Audra K. LANGLEY, Auteur ; James T. MCCRACKEN, Auteur . - 2010 . - p.616-626. Langues : Anglais (eng) in Journal of Clinical Child & Adolescent Psychology > 39-5 (September-October 2010) . - p.616-626 Index. décimale : PER Périodiques Résumé : Depression is the most common comorbidity among adults with obsessive compulsive disorder (OCD), yet little is known about depressive symptoms in childhood OCD. This study examined clinical and cognitive variables associated with depressive symptomatology in 71 youths (62% male, M age = 12.7 years) with primary OCD. Youths presented with a range of depressive symptoms, with 21% scoring at or above the clinical cutoff on the self-report measure of depression. Higher levels of depressive symptoms were associated with higher levels of cognitive distortions assessed on measures of insight, perceived control, competence, and contingencies. Depressive symptoms were also linked to older age and more severe OCD. Low perceived control and self-competence and high OCD severity independently predicted depression scores. En ligne : http://dx.doi.org/10.1080/15374416.2010.501285 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=108

Cognitive control processes in behavior therapy for youth with Tourette's disorder / Joseph F. MCGUIRE in Journal of Child Psychology and Psychiatry, 63-3 (March 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-3 (March 2022) . - p.296-304 Titre : Cognitive control processes in behavior therapy for youth with Tourette's disorder Type de document : texte imprimé Auteurs : Joseph F. MCGUIRE, Auteur ; Alexandra STURM, Auteur ; Emily J. RICKETTS, Auteur ; Gabrielle E. MONTALBANO, Auteur ; Susanna CHANG, Auteur ; Sandra K. LOO, Auteur ; Douglas W. WOODS, Auteur ; James T. MCCRACKEN, Auteur ; John PIACENTINI, Auteur Article en page(s) : p.296-304 Langues : Anglais (eng) Mots-clés : Cognitive control  behavior therapy  inhibition  inhibitory control  tic suppression Index. décimale : PER Périodiques Résumé : BACKGROUND: Cognitive control processes are implicated in the behavioral treatment of Tourette's disorder (TD). However, the influence of these processes on treatment outcomes has received minimal attention. This study examined whether cognitive control processes and/or tic suppression predicted reductions in tic severity and treatment response to behavior therapy. METHOD: Fifty-three youth with TD or a pervasive tic disorder participated in a randomized wait list-controlled trial of behavior therapy. Following a baseline assessment to evaluate psychiatric diagnoses, tic severity, and cognitive control processes (e.g., response selection, inhibition, and suppression), youth were randomly assigned to receive eight sessions of behavior therapy (n = 23) or a wait list of equal duration (n = 28). Youth receiving immediate treatment completed a post-treatment assessment to determine improvement in tic severity. Meanwhile, youth in the wait list condition completed another assessment to re-evaluate tic severity and cognitive control processes, and subsequently received 8 sessions of behavior therapy followed by a post-treatment assessment to determine improvement. RESULTS: A multiple linear regression model found that pretreatment inhibition/switching on the Delis-Kaplan Executive Function System Color-Word Interference Test predicted reductions in tic severity after behavior therapy (β = -.36, t = -2.35, p = .025, Æž(2)  = .15). However, other cognitive control processes and tic suppression did not predict treatment response and/or reductions in tic severity. Small nonsignificant effects were observed in cognitive control processes after behavior therapy. CONCLUSION: Cognitive control processes may influence tic severity reductions in behavior therapy. Notably, even when other cognitive control processes are impaired and youth are initially unable to voluntarily suppress their tics, youth with TD can still benefit from behavior therapy. Findings offer implications for clinical practice and research for TD. En ligne : http://dx.doi.org/10.1111/jcpp.13470 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457 [article] Cognitive control processes in behavior therapy for youth with Tourette's disorder [texte imprimé] / Joseph F. MCGUIRE, Auteur ; Alexandra STURM, Auteur ; Emily J. RICKETTS, Auteur ; Gabrielle E. MONTALBANO, Auteur ; Susanna CHANG, Auteur ; Sandra K. LOO, Auteur ; Douglas W. WOODS, Auteur ; James T. MCCRACKEN, Auteur ; John PIACENTINI, Auteur . - p.296-304. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-3 (March 2022) . - p.296-304 Mots-clés : Cognitive control  behavior therapy  inhibition  inhibitory control  tic suppression Index. décimale : PER Périodiques Résumé : BACKGROUND: Cognitive control processes are implicated in the behavioral treatment of Tourette's disorder (TD). However, the influence of these processes on treatment outcomes has received minimal attention. This study examined whether cognitive control processes and/or tic suppression predicted reductions in tic severity and treatment response to behavior therapy. METHOD: Fifty-three youth with TD or a pervasive tic disorder participated in a randomized wait list-controlled trial of behavior therapy. Following a baseline assessment to evaluate psychiatric diagnoses, tic severity, and cognitive control processes (e.g., response selection, inhibition, and suppression), youth were randomly assigned to receive eight sessions of behavior therapy (n = 23) or a wait list of equal duration (n = 28). Youth receiving immediate treatment completed a post-treatment assessment to determine improvement in tic severity. Meanwhile, youth in the wait list condition completed another assessment to re-evaluate tic severity and cognitive control processes, and subsequently received 8 sessions of behavior therapy followed by a post-treatment assessment to determine improvement. RESULTS: A multiple linear regression model found that pretreatment inhibition/switching on the Delis-Kaplan Executive Function System Color-Word Interference Test predicted reductions in tic severity after behavior therapy (β = -.36, t = -2.35, p = .025, Æž(2)  = .15). However, other cognitive control processes and tic suppression did not predict treatment response and/or reductions in tic severity. Small nonsignificant effects were observed in cognitive control processes after behavior therapy. CONCLUSION: Cognitive control processes may influence tic severity reductions in behavior therapy. Notably, even when other cognitive control processes are impaired and youth are initially unable to voluntarily suppress their tics, youth with TD can still benefit from behavior therapy. Findings offer implications for clinical practice and research for TD. En ligne : http://dx.doi.org/10.1111/jcpp.13470 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457

Cognitive functioning in affected sibling pairs with ADHD: familial clustering and dopamine genes / Sandra K. LOO in Journal of Child Psychology and Psychiatry, 49-9 (September 2008)  

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Correction to: Exploring Social Biomarkers in HighFunctioning Adults with Autism and Asperger's Versus Healthy Controls: A CrossSectional Analysis / Marta DEL VALLE RUBIDO in Journal of Autism and Developmental Disorders, 50-12 (December 2020)  

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Correlates of insight among youth with obsessive-compulsive disorder / Adam B. LEWIN in Journal of Child Psychology and Psychiatry, 51-5 (May 2010)  

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Design and Subject Characteristics in the Federally-Funded Citalopram Trial in Children with Pervasive Developmental Disorders / Lawrence SCAHILL in Journal of Autism and Developmental Disorders, 42-3 (March 2012)  

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Development and validation of an item response theory-based Social Responsiveness Scale short form / Alexandra STURM in Journal of Child Psychology and Psychiatry, 58-9 (September 2017)  

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Exploring Social Biomarkers in High-Functioning Adults with Autism and Asperger's Versus Healthy Controls: A Cross-Sectional Analysis / Marta DEL VALLE RUBIDO in Journal of Autism and Developmental Disorders, 50-12 (December 2020)  

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Exploring the Manifestations of Anxiety in Children with Autism Spectrum Disorders / Victoria HALLETT in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

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Factor structure and psychometric properties of the revised Home Situations Questionnaire for autism spectrum disorder: The Home Situations Questionnaire-Autism Spectrum Disorder / Monali CHOWDHURY in Autism, 20-5 (July 2016)  

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Gastrointestinal Symptoms in a Sample of Children with Pervasive Developmental Disorders / Roumen N. NIKOLOV in Journal of Autism and Developmental Disorders, 39-3 (March 2009)  

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In Search of Biomarkers for Autism Spectrum Disorder / Marta DEL VALLE RUBIDO in Autism Research, 11-11 (November 2018)  

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