[article] 
inJournal of Autism and Developmental Disorders > 44-10 (October 2014) . - p.2558-2567

Titre :	In Utero Exposure to Selective Serotonin Reuptake Inhibitors and Risk for Autism Spectrum Disorder
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Nicole B. GIDAYA, Auteur ; Brian K. LEE, Auteur ; Igor BURSTYN, Auteur ; Michael YUDELL, Auteur ; Erik L. MORTENSEN, Auteur ; Craig J. NEWSCHAFFER, Auteur
Article en page(s) :	p.2558-2567
Langues :	Anglais (eng)
Mots-clés :	Autism spectrum disorders  Selective serotonin reuptake inhibitors  Pregnancy  Depression
Index. décimale :	PER Périodiques
Résumé :	We investigated whether there is an association between increased risk for autism spectrum disorders (ASD) and selective serotonin reuptake inhibitors (SSRIs) used during pregnancy. This study used Denmark’s health and population registers to obtain information regarding prescription drugs, ASD diagnosis, and health and socioeconomic status. There were 1.5 % of cases and 0.7 % of controls exposed to SSRIs during the pregnancy period, and higher effect estimates observed with longer use. We found evidence that in utero exposure to SSRIs increases a child’s risk associated with ASD. These results, while adding to the limited knowledge on prenatal pharmacological exposures as potential ASD risk factors, need to be balanced against the benefits of indicated medication use by pregnant mothers.
En ligne :	http://dx.doi.org/10.1007/s10803-014-2128-4
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=240

[article] In Utero Exposure to Selective Serotonin Reuptake Inhibitors and Risk for Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Nicole B. GIDAYA, Auteur ; Brian K. LEE, Auteur ; Igor BURSTYN, Auteur ; Michael YUDELL, Auteur ; Erik L. MORTENSEN, Auteur ; Craig J. NEWSCHAFFER, Auteur . - p.2558-2567.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 44-10 (October 2014) . - p.2558-2567

Mots-clés :	Autism spectrum disorders  Selective serotonin reuptake inhibitors  Pregnancy  Depression
Index. décimale :	PER Périodiques
Résumé :	We investigated whether there is an association between increased risk for autism spectrum disorders (ASD) and selective serotonin reuptake inhibitors (SSRIs) used during pregnancy. This study used Denmark’s health and population registers to obtain information regarding prescription drugs, ASD diagnosis, and health and socioeconomic status. There were 1.5 % of cases and 0.7 % of controls exposed to SSRIs during the pregnancy period, and higher effect estimates observed with longer use. We found evidence that in utero exposure to SSRIs increases a child’s risk associated with ASD. These results, while adding to the limited knowledge on prenatal pharmacological exposures as potential ASD risk factors, need to be balanced against the benefits of indicated medication use by pregnant mothers.
En ligne :	http://dx.doi.org/10.1007/s10803-014-2128-4
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=240