[article]
| Titre : |
Modeling the Phenotypic Architecture of Autism Symptoms from Time of Diagnosis to Age 6 |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Stelios GEORGIADES, Auteur ; Michael H. BOYLE, Auteur ; Peter SZATMARI, Auteur ; Steven HANNA, Auteur ; Eric DUKU, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Susan E. BRYSON, Auteur ; Eric FOMBONNE, Auteur ; Joanne VOLDEN, Auteur ; Pat MIRENDA, Auteur ; Isabel SMITH, Auteur ; Wendy ROBERTS, Auteur ; Tracy VAILLANCOURT, Auteur ; Charlotte WADDELL, Auteur ; Teresa BENNETT, Auteur ; Mayada ELSABBAGH, Auteur ; Ann THOMPSON, Auteur |
| Article en page(s) : |
p.3045-3055 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Autism symptoms Classification Phenotypic heterogeneity |
| Index. décimale : |
PER Périodiques |
| Résumé : |
The latent class structure of autism symptoms from the time of diagnosis to age 6 years was examined in a sample of 280 children with autism spectrum disorder. Factor mixture modeling was performed on 26 algorithm items from the Autism Diagnostic Interview - Revised at diagnosis (Time 1) and again at age 6 (Time 2). At Time 1, a “2-factor/3-class” model provided the best fit to the data. At Time 2, a “2-factor/2-class” model provided the best fit to the data. Longitudinal (repeated measures) analysis of variance showed that the “2-factor/3-class” model derived at the time of diagnosis allows for the identification of a subgroup of children (9 % of sample) who exhibit notable reduction in symptom severity. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-014-2167-x |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=243 |
in Journal of Autism and Developmental Disorders > 44-12 (December 2014) . - p.3045-3055
[article] Modeling the Phenotypic Architecture of Autism Symptoms from Time of Diagnosis to Age 6 [Texte imprimé et/ou numérique] / Stelios GEORGIADES, Auteur ; Michael H. BOYLE, Auteur ; Peter SZATMARI, Auteur ; Steven HANNA, Auteur ; Eric DUKU, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Susan E. BRYSON, Auteur ; Eric FOMBONNE, Auteur ; Joanne VOLDEN, Auteur ; Pat MIRENDA, Auteur ; Isabel SMITH, Auteur ; Wendy ROBERTS, Auteur ; Tracy VAILLANCOURT, Auteur ; Charlotte WADDELL, Auteur ; Teresa BENNETT, Auteur ; Mayada ELSABBAGH, Auteur ; Ann THOMPSON, Auteur . - p.3045-3055. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 44-12 (December 2014) . - p.3045-3055
| Mots-clés : |
Autism symptoms Classification Phenotypic heterogeneity |
| Index. décimale : |
PER Périodiques |
| Résumé : |
The latent class structure of autism symptoms from the time of diagnosis to age 6 years was examined in a sample of 280 children with autism spectrum disorder. Factor mixture modeling was performed on 26 algorithm items from the Autism Diagnostic Interview - Revised at diagnosis (Time 1) and again at age 6 (Time 2). At Time 1, a “2-factor/3-class” model provided the best fit to the data. At Time 2, a “2-factor/2-class” model provided the best fit to the data. Longitudinal (repeated measures) analysis of variance showed that the “2-factor/3-class” model derived at the time of diagnosis allows for the identification of a subgroup of children (9 % of sample) who exhibit notable reduction in symptom severity. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-014-2167-x |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=243 |
|
Modeling the Phenotypic Architecture of Autism Symptoms from Time of Diagnosis to Age 6 in Journal of Autism and Developmental Disorders, 44-12 (December 2014)
